Abstract: The large distances travelled by neutrinos emitted from the Sun and core -collapse supernovae together with the characteristic energy of such neutrinos provide ideal conditions to probe their lifetime, when the decay products evade detection. We investigate the prospects of probing invisible neutrino decay capitalising on the detection of solar and supernova neutrinos as well as the diffuse supernova neutrino background (DSNB) in the next -generation neutrino observatories Hyper-Kamiokande, DUNE, JUNO, DARWIN, and RES-NOVA. We find that future solar neutrino data will be sensitive to values of the lifetime -to -mass ratio tau 1 /m 1 and tau 2 /m 2 of O(10 – 1 -10 – 2 ) s/eV. From a core -collapse supernova explosion at 10 kpc, lifetime -to -mass ratios of the three mass eigenstates of O(10 5 ) s/eV could be tested. After 20 years of data taking, the DSNB would extend the sensitivity reach of tau 1 /m 1 to 10 8 s/eV. These results promise an improvement of about 6-15 orders of magnitude on the values of the decay parameters with respect to existing limits.