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Author |
Trbojevich, R.A.; Fernandez, A.; Watanabe, F.; Mustafa, T.; Bryant, M.S. |
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Title |
Comparative study of silver nanoparticle permeation using Side-Bi-Side and Franz diffusion cells |
Type |
Journal Article |
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Year |
2016 |
Publication  |
Journal of Nanoparticle Research |
Abbreviated Journal |
J. Nanopart. Res. |
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Volume |
18 |
Issue |
3 |
Pages |
55 - 12pp |
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Keywords |
Membranes; Silver nanoparticles; Diffusion cells; Food packaging; Permeation; Environmental and health effects |
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Abstract |
Better understanding the mechanisms of nanoparticle permeation through membranes and packaging polymers has important implications for the evaluation of drug transdermal uptake, in food safety and the environmental implications of nanotechnology. In this study, permeation of 21 nm diameter silver nanoparticles (AgNPs) was tested using Side-Bi-Side and Franz static diffusion cells through hydrophilic 0.1 and 0.05 lm pore diameter 125 μm thick synthetic cellulose membranes, and 16 and 120 μm thick low-density polyethylene (LDPE) films. Experiments performed with LDPE films discarded permeation of AgNPs or Ag ions over the investigated time-frame in both diffusion systems. But controlled release of AgNPs has been quantified using semipermeable hydrophilic membranes. The permeation followed a quasi-linear time-dependent model during the experimental time-frame, which represents surface reaction-limited permeation. Diffusive flux, diffusion coefficients, and membrane permeability were determined as a function of pore size and diffusion model. Concentration gradient and pore size were key to understand mass transfer phenomena in the diffusion systems. |
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Address |
[Trbojevich, Raul A.; Bryant, Matthew S.] US FDA, Div Biochem Toxicol, Natl Ctr Toxicol Res, 3900 NCTR Rd, Jefferson, AR 72079 USA, Email: velifdez@ific.uv.es |
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Springer |
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English |
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ISSN |
1388-0764 |
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Notes |
WOS:000387044400002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2849 |
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Author |
Bonilla, C.; Sokolowska, D.; Darvishi, N.; Diaz-Cruz, J.L.; Krawczyk, M. |
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Title |
IDMS: inert dark matter model with a complex singlet |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Physics G |
Abbreviated Journal |
J. Phys. G |
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Volume |
43 |
Issue |
6 |
Pages |
065001 - 39pp |
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Keywords |
CP violation; inert doublet model; complex singlet |
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Abstract |
We study an extension of the inert doublet model (IDM) that includes an extra complex singlet of the scalars fields, which we call the IDMS. In this model there are three Higgs particles, among them a SM-like Higgs particle, and the lightest neutral scalar, from the inert sector, remains a viable dark matter (DM) candidate. We assume a non-zero complex vacuum expectation value for the singlet, so that the visible sector can introduce extra sources of CP violation. We construct the scalar potential of IDMS, assuming an exact Z(2) symmetry, with the new singlet being Z(2)-even, as well as a softly broken U(1) symmetry, which allows a reduced number of free parameters in the potential. In this paper we explore the foundations of the model, in particular the masses and interactions of scalar particles for a few benchmark scenarios. Constraints from collider physics, in particular from the Higgs signal observed at the Large Hadron Collider with M-h approximate to 125 GeV, as well as constraints from the DM experiments, such as relic density measurements and direct detection limits, are included in the analysis. We observe significant differences with respect to the IDM in relic density values from additional annihilation channels, interference and resonance effects due to the extended Higgs sector. |
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Address |
[Bonilla, Cesar] Univ Valencia, CSIC, Inst Fis Corpuscular, Apdo 22085, E-46071 Valencia, Spain, Email: cesar.bonilla@ific.uv.es; |
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Publisher |
Iop Publishing Ltd |
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English |
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ISSN |
0954-3899 |
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Conference |
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Notes |
WOS:000376276900002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2687 |
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Author |
KM3NeT Collaboration (Adrian-Martinez, S. et al); Barrios-Marti, J.; Calvo Diaz-Aldagalan, D.; Hernandez-Rey, J.J.; Illuminati, G.; Lotze, M.; Olcina, I.; Real, D.; Sanchez Garcia, A.; Tönnis, C.; Zornoza, J.D.; Zuñiga, J. |
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Title |
Letter of intent for KM3NeT 2.0 |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Physics G |
Abbreviated Journal |
J. Phys. G |
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Volume |
43 |
Issue |
8 |
Pages |
084001 - 130pp |
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Keywords |
neutrino astronomy; neutrino physics; deep sea neutrino telescope; neutrino mass hierarchy |
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Abstract |
The main objectives of the KM3NeT Collaboration are (i) the discovery and subsequent observation of high-energy neutrino sources in the Universe and (ii) the determination of the mass hierarchy of neutrinos. These objectives are strongly motivated by two recent important discoveries, namely: (1) the high-energy astrophysical neutrino signal reported by IceCube and (2) the sizable contribution of electron neutrinos to the third neutrino mass eigenstate as reported by Daya Bay, Reno and others. To meet these objectives, the KM3NeT Collaboration plans to build a new Research Infrastructure consisting of a network of deep-sea neutrino telescopes in the Mediterranean Sea. A phased and distributed implementation is pursued which maximises the access to regional funds, the availability of human resources and the synergistic opportunities for the Earth and sea sciences community. Three suitable deep-sea sites are selected, namely off-shore Toulon (France), Capo Passero (Sicily, Italy) and Pylos (Peloponnese, Greece). The infrastructure will consist of three so-called building blocks. A building block comprises 115 strings, each string comprises 18 optical modules and each optical module comprises 31 photo-multiplier tubes. Each building block thus constitutes a three-dimensional array of photo sensors that can be used to detect the Cherenkov light produced by relativistic particles emerging from neutrino interactions. Two building blocks will be sparsely configured to fully explore the IceCube signal with similar instrumented volume, different methodology, improved resolution and complementary field of view, including the galactic plane. One building block will be densely configured to precisely measure atmospheric neutrino oscillations. |
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Address |
[Adrian-Martinez, S.; Ardid, M.; Llorens Alvarez, C. D.; Martinez-Mora, J. A.; Saldana, M.] Univ Politecn Valencia, Inst Invest Gest Integrada Zonas Costeras, C Paranimf 1, E-46730 Gandia, Spain, Email: brunner@cppm.in2p3.fr; |
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Iop Publishing Ltd |
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English |
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ISSN |
0954-3899 |
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Conference |
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Notes |
WOS:000381686700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2773 |
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Author |
Ayala, C.; Gonzalez, P.; Vento, V. |
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Title |
Heavy quark potential from QCD-related effective coupling |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Physics G |
Abbreviated Journal |
J. Phys. G |
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Volume |
43 |
Issue |
12 |
Pages |
125002 - 12pp |
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Keywords |
general properties of QCD; potential models; other non-perturbative calculations; heavy quarkonia |
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Abstract |
We implement our past investigations of quark-antiquark interaction through a non-perturbative running coupling defined in terms of a gluon mass function, similar to that used in some Schwinger-Dyson approaches. This coupling leads to a quark-antiquark potential, which satisfies not only asymptotic freedom but also describes linear confinement correctly. From this potential, we calculate the bottomonium and charmonium spectra below the first open flavor meson-meson thresholds and show that for a small range of values of the free parameter determining the gluon mass function an excellent agreement with data is attained. |
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Address |
[Gonzalez, Pedro] Univ Valencia, Dept Theoret Phys, E-46100 Valencia, Spain, Email: Pedro.Gonzalez@uv.es |
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Publisher |
Iop Publishing Ltd |
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English |
Summary Language |
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Series Volume |
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ISSN |
0954-3899 |
ISBN |
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Conference |
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Notes |
WOS:000388219700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2870 |
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Author |
Gimenez-Alventosa, V.; Vijande, J.; Ballester, F.; Perez-Calatayud, J. |
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Title |
Transit dose comparisons for Co-60 and Ir-192 HDR sources |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Radiological Protection |
Abbreviated Journal |
J. Radiol. Prot. |
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Volume |
36 |
Issue |
4 |
Pages |
858-864 |
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Keywords |
Monte Carlo; dosimetry; HDR brachytherapy; transit dose |
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Abstract |
The goal of this study is to evaluate the ambient dose due to the transit of high dose rate (HDR) Co-60 sources along a transfer tube as compared to Ir-192 ones in a realistic clinical scenario. This goal is accomplished by evaluating air-kerma differences with Monte Carlo calculations using PENELOPE2011. Scatter from both the afterloader and the patient was not taken into account. Two sources, mHDR-v2 and Flexisource Co-60, (Elekta Brachytherapy, Veenendaal, the Netherlands) have been considered. These sources were simulated within a standard transfer tube located in an infinite air phantom. The movement of the source was included by displacing their positions along the connecting tube from z = – 75 cm to z = + 75 cm and combining them. Since modern afterloaders like Flexitron (Elekta) or Saginova (BEBIG GmbH) are able to use equally 192Ir and 60Co sources, it was assumed that both sources are displaced with equal speed. Typical HDR source activity content values were provided by the manufacturer. 2D distributions were obtained with type-A uncertainties (k = 2) less than 0.01%. From those, the air-kerma ratio Co-60/Ir-192 was evaluated weighted by their corresponding typical activities. It was found that it varies slowly with distance (less than 10% variation at 75 cm) but strongly in time due to the shorter half-life of the 192Ir (73.83 d). The maximum ratio is located close to the tube. It reaches a value of 0.57 when the typical activity of the sources at the time when they were installed by the vendor was used. Such ratio increases up to 1.28 at the end of the recommended working life (90 d) of the Ir-192 source. Co-60/Ir-192 air-kerma ratios are almost constant (0.51-0.57) in the vicinity of the source-tube with recent installed sources. Nevertheless, air-kerma ratios increase rapidly (1.15-1.29) whenever the Ir-192 is approaching the end of its life. In case of a medical event requiring the medical staff to access the treatment room, these ratios indicate that the dosimetric impact on the medical team will be lower, with a few exceptions, in the case of Co-60-based HDR brachytherapy as compared to Ir-192-based one when typical air-kerma strength values are considered. |
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Address |
[Gimenez-Alventosa, Vicent; Vijande, Javier; Ballester, Facundo] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: javier.vijande@uv.es |
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Publisher |
Iop Publishing Ltd |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0952-4746 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000386436100002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2839 |
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Author |
Lloret, E.; Picouet, P.A.; Trbojevich, R.; Fernandez, A. |
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Title |
Colour stability of cooked ham packed under modified atmospheres in polyamide nanocomposite blends |
Type |
Journal Article |
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Year |
2016 |
Publication |
Lwt-Food Science And Technology |
Abbreviated Journal |
LWT-Food Sci. Technol. |
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Volume |
66 |
Issue |
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Pages |
582-589 |
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Keywords |
Nylon; Cooked ham; Nanoclays; Oxygen permeation; Colour; Exfoliation; MAP |
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Abstract |
Two novel blends containing a low-density polyethylene (LDPE) and a neat polyamide (PA) or a polyamide nanocomposite (PAN) layers were fabricated and their technological potential was evaluated during the refrigeration of cooked ham in modified atmospheres (MAP). Nanoclays were homogeneously distributed and nearly exfoliated, and they lowered significantly the oxygen transmission rate (OTR) of the PAN films. Due to the lower OTR, the headspace oxygen level in PAN pouches do not rise above 0.26% but it approached 2% in PA pouches at day 20. The residual oxygen levels were key for colour change during MAP storage of cooked ham. Cooked ham redness and reflectivity were stable during 27 days in PAN pouches while a strong colour deterioration took place after day 7 in PA pouches. Other parameters such as moisture content and water activity remained unaltered, and pH development was related to microbial growth and independent of the packaging polymer. The evolution of cooked ham colour in PAN was comparable to a high-barrier commercial polymer, and was acceptable for commercial sale for 27 days, showing excellent perspectives for polyamide nanocomposites in the storage of cooked ham. |
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Address |
[Lloret, Elsa; Picouet, Pierre A.] IRTA, Dept Tecnol Dels Aliments, Monells, Girona, Spain, Email: velifdez@ific.uv.es |
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Publisher |
Elsevier Science Bv |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0023-6438 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000367413200079 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2510 |
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Author |
Lloret, E.; Fernandez, A.; Trbojevich, R.; Arnau, J.; Picouet, P.A. |
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Title |
Relevance of nanocomposite packaging on the stability of vacuum-packed dry cured ham |
Type |
Journal Article |
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Year |
2016 |
Publication |
Meat Science |
Abbreviated Journal |
Meat Sci. |
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Volume |
118 |
Issue |
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Pages |
8-14 |
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Keywords |
Clay; Nanocomposite; Polyamide; Skin; TBARS; Vacuum; Meat; Ham |
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Abstract |
In this study effects of a novel high barrier multilayer polyamide film containing dispersed nanoclays (PAN) on the stability of vacuum packed dry-cured ham were investigated during 90 days refrigerated storage in comparison with non-modified multilayer polyamide (PA) and a commercial high barrier film. Characteristic bands of the mineral in FT-IR spectra confirmed the presence of nanoclays in PAN, enhancing oxygen transmission barrier properties and UV protection. Packaging in PAN films did not originate significant changes on colour or lipid oxidation during prolonged storage of vacuum-packed dry-cured ham. Larger oxygen transmission rates in PA films caused changes in CIE b* during refrigerated storage. Ham quality was not affected by light exposition during 90 days and only curing had a significant benefit on colour and TBARS, being cured samples more stable during storage in all the packages used. Packaging of dry-cured ham in PAN was equivalent to commercial high barrier films. |
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Address |
[Lloret, Elsa; Arnau, Jacint; Picouet, Pierre A.] IRTA, Dept Tecnol Aliments, Monells, Girona, Spain, Email: pierre.picouet@irta.cat |
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Publisher |
Elsevier Sci Ltd |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0309-1740 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000380581100002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2774 |
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Author |
Candela-Juan, C.; Niatsetski, Y.; van der Laarse, R.; Granero, D.; Ballester, F.; Perez-Calatayud, J.; Vijande, J. |
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Title |
Design and characterization of a new high-dose-rate brachytherapy Valencia applicator for larger skin lesions |
Type |
Journal Article |
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Year |
2016 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
43 |
Issue |
4 |
Pages |
1639-1648 |
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Keywords |
skin applicator; Valencia applicator; HDR brachytherapy; dosimetry; Monte Carlo |
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Abstract |
Purpose: The aims of this study were (i) to design a new high-dose-rate (HDR) brachytherapy applicator for treating surface lesions with planning target volumes larger than 3 cm in diameter and up to 5 cm in size, using the microSelectron-HDR or Flexitron afterloader (Elekta Brachytherapy) with a Ir-192 source; (ii) to calculate by means of the Monte Carlo (MC) method the dose distribution for the new applicator when it is placed against a water phantom; and (iii) to validate experimentally the dose distributions in water. Methods: The PENELOPE2008 MC code was used to optimize dwell positions and dwell times. Next, the dose distribution in a water phantom and the leakage dose distribution around the applicator were calculated. Finally, MC data were validated experimentally for a 192Ir mHDR-v2 source by measuring (i) dose distributions with radiochromic EBT3 films (ISP); (ii) percentage depth-dose (PDD) curve with the parallel-plate ionization chamber Advanced Markus (PTW); and (iii) absolute dose rate with EBT3 films and the PinPoint T31016 (PTW) ionization chamber. Results: The new applicator is made of tungsten alloy (Densimet) and consists of a set of interchangeable collimators. Three catheters are used to allocate the source at prefixed dwell positions with preset weights to produce a homogenous dose distribution at the typical prescription depth of 3 mm in water. The same plan is used for all available collimators. PDD, absolute dose rate per unit of air kerma strength, and off-axis profiles in a cylindrical water phantom are reported. These data can be used for treatment planning. Leakage around the applicator was also scored. The dose distributions, PDD, and absolute dose rate calculated agree within experimental uncertainties with the doses measured: differences of MC data with chamber measurements are up to 0.8% and with radiochromic films are up to 3.5%. Conclusions: The new applicator and the dosimetric data provided here will be a valuable tool in clinical practice, making treatment of large skin lesions simpler, faster, and safer. Also the dose to surrounding healthy tissues is minimal. |
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Address |
[Candela-Juan, C.; Perez-Calatayud, J.] La Fe Univ & Polytech Hosp, Dept Radiat Oncol, Valencia 46026, Spain, Email: ccanjuan@gmail.com |
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Publisher |
Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0094-2405 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000373711000007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2620 |
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Author |
Granero, D.; Candela-Juan, C.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Jacob, D.; Mourtada, F. |
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Title |
Technical Note: Dosimetry of Leipzig and Valencia applicators without the plastic cap |
Type |
Journal Article |
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Year |
2016 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
43 |
Issue |
5 |
Pages |
2087 - 4pp |
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Keywords |
Leipzig applicators; Valencia applicators; skin brachytherapy; Monte Carlo; dosimetry |
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Abstract |
Purpose: High dose rate (HDR) brachytherapy for treatment of small skin lesions using the Leipzig and Valencia applicators is a widely used technique. These applicators are equipped with an attachable plastic cap to be placed during fraction delivery to ensure electronic equilibrium and to prevent secondary electrons from reaching the skin surface. The purpose of this study is to report on the dosimetric impact of the cap being absent during HDR fraction delivery, which has not been explored previously in the literature. Methods: GEANT4 Monte Carlo simulations (version 10.0) have been performed for the Leipzig and Valencia applicators with and without the plastic cap. In order to validate the Monte Carlo simulations, experimental measurements using radiochromic films have been done. Results: Dose absorbed within 1 mm of the skin surface increases by a factor of 1500% for the Leipzig applicators and of 180% for the Valencia applicators. Deeper than 1 mm, the overdosage flattens up to a 10% increase. Conclusions: Differences of treating with or without the plastic cap are significant. Users must check always that the plastic cap is in place before any treatment in order to avoid overdosage of the skin. Prior to skin HDR fraction delivery, the timeout checklist should include verification of the cap placement. (C) 2016 American Association of Physicists in Medicine. |
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Address |
[Granero, D.] Hosp Gen Univ, Dept Radiat Phys, ERESA, Valencia 46014, Spain, Email: dgranero@eresa.com |
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Publisher |
Amer Assoc Physicists Medicine Amer Inst Physics |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0094-2405 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000378924200010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2753 |
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Author |
Abbas, G. |
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Title |
Right-right-left extension of the Standard Model |
Type |
Journal Article |
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Year |
2016 |
Publication |
Modern Physics Letters A |
Abbreviated Journal |
Mod. Phys. Lett. A |
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Volume |
31 |
Issue |
19 |
Pages |
1650117 - 10pp |
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Keywords |
Extension of the gauge sector; parity |
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Abstract |
A right-right-left extension of the Standard Model is proposed. In this model, SM gauge group SU(2)(L) circle times U(1)(Y) is extended to SU(2)(L) circle times SU(2)(R) circle times SU(2)'(R) circle times SU(2)'(L) circle times U(1)(Y). The gauge symmetries SU(2)'(R), SU(2)'(L) are the mirror counterparts of the SU(2)(L) and SU(2)(R), respectively. Parity is spontaneously broken when the scalar Higgs fields acquire vacuum expectation values (VEVs) in a certain pattern. Parity is restored at the scale of SU(2)'(L). The gauge sector has a unique pattern. The scalar sector of the model is optimum, elegant and unique. |
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Address |
[Abbas, Gauhar] Univ Valencia, CSIC, IFIC, Apt Correus 22085, E-46071 Valencia, Spain, Email: Gauhar.Abbas@ific.uv.es |
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Publisher |
World Scientific Publ Co Pte Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Edition |
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ISSN |
0217-7323 |
ISBN |
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Conference |
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Notes |
WOS:000379143800006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2751 |
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