Carles, M., Lerche, C. W., Sanchez, F., Mora, F., & Benlloch, J. M. (2011). Position correction with depth of interaction information for a small animal PET system. Nucl. Instrum. Methods Phys. Res. A, 648, S176–S180.
Abstract: In this work we study the effects on the spatial resolution when depth of interaction (001) information is included in the parameterization of the line of response (LOR) for a small animal positron emission tomography (PET) system. One of the most important degrading factors for PET is the parallax error introduced in systems that do not provide DOI information of the recorded gamma-rays. Our group has designed a simple and inexpensive method for DOI determination in continuous scintillation crystals. This method is based, on one hand, in the correlation between the scintillation light distribution width in monolithic crystals and the DOI, and, on the other hand, on a small modification of the widely applied charge dividing circuits (CDR). In this work we present a new system calibration that includes the DOI information, and also the development of the correction equations that relates the LOR without and with DOI information. We report the results obtained for different measurements along the transaxial field of view (FOV) and the image quality enhancement achieved specially at the edge of the FOV.
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Llosa, G., Barrio, J., Lacasta, C., Callier, S., Raux, L., & de La Taille, C. (2011). First tests in the application of silicon photomultiplier arrays to dose monitoring in hadron therapy. Nucl. Instrum. Methods Phys. Res. A, 648, S96–S99.
Abstract: A detector head composed of a continuous LaBr3 crystal coupled to a silicon photomultiplier array has been mounted and tested, for its use in a Compton telescope for dose monitoring in hadron therapy. The LaBr3 crystal has 16 mm x 18 mm x 5 mm size, and it is surrounded with reflecting material in five faces. The SiPM array has 16 (4 x 4) elements of 3 mm x 3 mm size. The SPIROC1 ASIC has been employed as readout electronics. The detector shows a linear behavior up to 1275 keV. The energy resolution obtained at 511 keV is 7% FWHM, and it varies as one over the square root of the energy up to the energies tested. The variations among the detector channels are within 12%. A preliminary measurement of the timing resolution gives 7 ns FWHM. The spatial resolution obtained with the center of gravity method is 1.2 mm FWHM. The tests performed confirm the correct functioning of the detector.
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Soriano, A., Gonzalez, A., Orero, A., Moliner, L., Carles, M., Sanchez, F., et al. (2011). Attenuation correction without transmission scan for the MAMMI breast PET. Nucl. Instrum. Methods Phys. Res. A, 648, S75–S78.
Abstract: Whole-body Positron Emission Tomography (PET) scanners are required in order to span large Fields of View (FOV). Therefore, reaching the sensitivity and spatial resolution required for early stage breast tumor detection is not straightforward. MAMMI is a dedicated breast PET scanner with a ring geometry designed to provide PET images with a spatial resolution as high as 1.5 mm, being able to detect small breast tumors ( < 1 cm). The patient lays down in prone position during the scan, thus making possible to image the whole breast, up to regions close to the base of the pectoral without the requirement of breast compression. Attenuation correction (AC) for PET data improves the image quality and the quantitative accuracy of radioactivity distribution determination. In dedicated, high resolution breast cancer scanners, this correction would enhance the proper diagnosis in early disease stages. In whole-body PET scanners, AC is usually taken into account with the use of transmission scans, either by external radioactive rod sources or by Computed Tomography (CT). This considerably increases the radiation dose administered to the patient and time needed for the exploration. In this work we propose a method for breast shape identification by means of PET image segmentation. The breast shape identification will be used for the determination of the AC. For the case of a specific breast PET scanner the procedure we propose should provide AC similar to that obtained by transmission scans as we take advantage of the breast anatomical simplicity. Experimental validation of the proposed approach with a dedicated breast PET prototype is also presented. The main advantage of this method is an important dose reduction since the transmission scan is not required.
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Studen, A., Chesi, E., Cindro, V., Clinthorne, N. H., Cochran, E., Grosicar, B., et al. (2011). A silicon PET probe. Nucl. Instrum. Methods Phys. Res. A, 648, S255–S258.
Abstract: PET scanners with high spatial resolution offer a great potential in improving diagnosis, therapy monitoring and treatment validation for several severe diseases. One way to improve resolution of a PET scanner is to extend a conventional PET ring with a small probe with excellent spatial resolution. The probe is intended to be placed close to the area of interest. The coincidences of interactions within the probe and the external ring provide a subset of data which combined with data from external ring, greatly improve resolution in the area viewed by the probe. Our collaboration is developing a prototype of a PET probe, composed of high-resolution silicon pad detectors. The detectors are 1 mm thick, measuring 40 by 26 mm(2), and several such sensors are envisaged to either compensate for low stopping power of silicon or increase the area covered by the probe. The sensors are segmented into 1 mm(3) cubic voxels, giving 1040 readout pads per sensor. A module is composed of two sensors placed in a back-to-back configuration, allowing for stacking fraction of up to 70% within a module. The pads are coupled to a set of 16 ASICs (VaTaGP7.1 by IDEAS) per module and read out through a custom designed data acquisition board, allowing for trigger and data interfacing with the external ring. This paper presents an overview of probe requirements and expected performance parameters. It will focus on the characteristics of the silicon modules and their impact on overall probe performance, including spatial resolution, energy resolution and timing resolution. We will show that 1 mm(3) voxels will significantly extend the spatial resolution of conventional PET rings, and that broadening of timing resolution related to varying depth of photon interactions can be compensated to match the timing resolution of the external ring. The initial test results of the probe will also be presented.
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AGATA Collaboration, Doncel, M., Quintana, B., Gadea, A., Recchia, F., & Farnea, E. (2011). Background rejection capabilities of a Compton imaging telescope setup with a DSSD Ge planar detector and AGATA. Nucl. Instrum. Methods Phys. Res. A, 648, S131–S134.
Abstract: In this work, we show the first Monte Carlo results about the performance of the Ge array which we propose for the DESPEC experiment at FAIR, when the background algorithm developed for AGATA is applied. The main objective of our study is to characterize the capabilities of the gamma-spectroscopy system, made up of AGATA detectors in a semi-spherical distribution covering a 1 pi solid angle and a set of planar Ge detectors in a daisy configuration, to discriminate between gamma sources placed at different locations.
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Mayoral, C., Recati, A., Fabbri, A., Parentani, R., Balbinot, R., & Carusotto, I. (2011). Acoustic white holes in flowing atomic Bose-Einstein condensates. New J. Phys., 13, 025007–29pp.
Abstract: We study acoustic white holes in a steadily flowing atomic Bose-Einstein condensate. A white hole configuration is obtained when the flow velocity goes from a super-sonic value in the upstream region to a sub-sonic one in the downstream region. The scattering of phonon wavepackets on a white hole horizon is numerically studied in terms of the Gross-Pitaevskii equation of mean-field theory: dynamical stability of the acoustic white hole is found, as well as a signature of a nonlinear back-action of the incident phonon wavepacket onto the horizon. The correlation pattern of density fluctuations is numerically studied by means of the truncated-Wigner method, which includes quantum fluctuations. Signatures of the white hole radiation of correlated phonon pairs by the horizon are characterized; analogies and differences with Hawking radiation from acoustic black holes are discussed. In particular, a short wavelength feature is identified in the density correlation function, whose amplitude steadily grows in time since the formation of the horizon. The numerical observations are quantitatively interpreted by means of an analytical Bogoliubov theory of quantum fluctuations for a white hole configuration within the step-like horizon approximation.
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Schwetz, T., Tortola, M., & Valle, J. W. F. (2011). Global neutrino data and recent reactor fluxes: the status of three-flavour oscillation parameters. New J. Phys., 13, 063004–15pp.
Abstract: We present the results of a global neutrino oscillation data analysis within the three-flavour framework. We include the latest results from the MINOS long-baseline experiment (including electron neutrino appearance and anti-neutrino data), updating all relevant solar (Super-Kamiokande (SK) II + III), atmospheric (SK I + II + III) and reactor (KamLAND) data. Furthermore, we include a recent re-calculation of the anti-neutrino fluxes emitted from nuclear reactors. These results have important consequences for the analysis of reactor experiments and in particular for the status of the mixing angle theta(13). In our recommended default analysis, we find from the global fit that the hint for nonzero theta(13) remains weak, at 1.8 sigma for both neutrino mass hierarchy schemes. However, we discuss in detail the dependence of these results on assumptions regarding the reactor neutrino analysis.
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ATLAS Collaboration(Aad, G. et al), Amoros, G., Cabrera Urban, S., Castillo Gimenez, V., Costa, M. J., Escobar, C., et al. (2011). Charged-particle multiplicities in pp interactions measured with the ATLAS detector at the LHC. New J. Phys., 13, 053033–68pp.
Abstract: Measurements are presented from proton-proton collisions at centre-of-mass energies of root s = 0.9, 2.36 and 7 TeV recorded with the ATLAS detector at the LHC. Events were collected using a single-arm minimum-bias trigger. The charged-particle multiplicity, its dependence on transverse momentum and pseudorapidity and the relationship between the mean transverse momentum and charged-particle multiplicity are measured. Measurements in different regions of phase space are shown, providing diffraction-reduced measurements as well as more inclusive ones. The observed distributions are corrected to well-defined phase-space regions, using model-independent corrections. The results are compared to each other and to various Monte Carlo (MC) models, including a new AMBT1 pythia6 tune. In all the kinematic regions considered, the particle multiplicities are higher than predicted by the MC models. The central charged-particle multiplicity per event and unit of pseudorapidity, for tracks with p(T) > 100 MeV, is measured to be 3.483 +/- 0.009 (stat) +/- 0.106 (syst) at root s = 0.9 TeV and 5.630 +/- 0.003 (stat) +/- 0.169 (syst) at root s = 7 TeV.
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ATLAS Collaboration(Aad, G. et al), Amoros, G., Cabrera Urban, S., Castillo Gimenez, V., Costa, M. J., Escobar, C., et al. (2011). A search for new physics in dijet mass and angular distributions in pp collisions at sqrt(s)=7 TeV measured with the ATLAS detector. New J. Phys., 13, 053044–44pp.
Abstract: A search for new interactions and resonances produced in LHC proton-proton (pp) collisions at a centre-of-mass energy root s = 7 TeV was performed with the ATLAS detector. Using a dataset with an integrated luminosity of 36 pb(-1), dijet mass and angular distributions were measured up to dijet masses of similar to 3.5 TeV and were found to be in good agreement with Standard Model predictions. This analysis sets limits at 95% CL on various models for new physics: an excited quark is excluded for mass between 0.60 and 2.64 TeV, an axigluon hypothesis is excluded for axigluon masses between 0.60 and 2.10 TeV and quantum black holes are excluded in models with six extra space-time dimensions for quantum gravity scales between 0.75 and 3.67 TeV. Production cross section limits as a function of dijet mass are set using a simplified Gaussian signal model to facilitate comparisons with other hypotheses. Analysis of the dijet angular distribution using a novel technique simultaneously employing the dijet mass excludes quark contact interactions with a compositeness scale 3 below 9.5 TeV.
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Schwetz, T., Tortola, M., & Valle, J. W. F. (2011). Where we are on theta(13): addendum to 'Global neutrino data and recent reactor fluxes: status of three-flavor oscillation parameters'. New J. Phys., 13, 109401–5pp.
Abstract: In this addendum to Schwetz et al (2011 New J. Phys. 13 063004), we consider the recent results from long-baseline nu(mu) -> nu(e) searches at the Tokai to Kamioka (T2K) and Main Injector Neutrino Oscillation Search (MINOS) experiments and investigate their implications for the mixing angle theta(13) and the leptonic Dirac CP phase delta. By combining the 2.5 sigma indication for a nonzero value of theta(13) coming from the T2K data with global neutrino oscillation data, we obtain a significance for theta(13) > 0 of about 3 sigma with best fit points sin(2) theta(13) = 0.013 (0.016) for normal (inverted) neutrino mass ordering. These results depend somewhat on assumptions concerning the analysis of reactor neutrino data.
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