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Koolen, B. B., Vidal-Sicart, S., Benlloch, J. M., & Olmos, R. A. V. (2014). Evaluating heterogeneity of primary tumor 18 F-FDG uptake in breast cancer with a dedicated breast PET ( MAMMI): a feasibility study based on correlation with PET/CT. Nucl. Med. Commun., 35(5), 446–452.
Abstract: PurposeThe aim of the study was to evaluate the heterogeneity of primary tumor F-18-fluorodeoxyglucose (F-18-FDG) uptake in breast cancer patients using a dedicated breast PET.Patients and methodsA positron emission tomography/computed tomography (PET/CT) of the thorax was performed 60 min after administration of 180-240 MBq of F-18-FDG in patients with breast cancer. Subsequently, 110 min after injection, a scan was taken with a dedicated high-resolution breast PET [MAMmography with Molecular Imaging (MAMMI)]. Both procedures were performed with the patients in the prone position. Four-point scores were used to compare the intensity (0: none; 1: mild; 2: moderate; 3: high) and heterogeneity (0: none; 1: mild; 2: moderate; 3: high) of F-18-FDG uptake between PET/CT and MAMMI images.ResultsThirty-five patients in whom the primary tumor was visualized on both scans were included in this analysis. The mean primary tumor size was 35.1 mm (range 10-108 mm). The mean intensity score was similar on both devices (2.4 for PET/CT and 2.3 for MAMMI; P=0.439), but the mean heterogeneity score on MAMMI images was significantly higher (PET/CT 1.9 vs. MAMMI 2.3; P=0.005). MAMMI showed a higher heterogeneity score in 11 (31%) of 35 patients, especially in tumors with moderate or high intensity. Significantly higher heterogeneity scores on both PET/CT and MAMMI were seen in large tumors (P=0.005 and 0.014, respectively) and in tumors with high intensity scores (P=0.012 and P<0.001, respectively).ConclusionHeterogeneous tumor F-18-FDG uptake in breast cancer is frequently observed, particularly in large tumors with intense F-18-FDG uptake. It is more often seen on MAMMI PET than on conventional PET/CT. Although the observed heterogeneity should be proven histopathologically, this finding offers a rationale for F-18-FDG-guided biopsies.
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Campanario, F., Rauch, M., & Sapeta, S. (2014). W+W- production at high transverse momenta beyond NLO. Nucl. Phys. B, 879, 65–79.
Abstract: Pair production of W gauge bosons is an important process at the LHC entering many experimental analyses, both as background in new-physics searches or Higgs measurements and as signal in precision studies and tests of the Standard Model. Therefore, accurate predictions for this class of processes are of great interest in order to exploit the full potential of LHC measurements. We use the LoopSim method to combine NLO QCD results for WW and WW + jet, as well as the loop-squared gluon-fusion contribution, to obtain approximate NNLO predictions for WW production. The cross sections are calculated with VBFNLO and include leptonic decays of the W bosons as well as finite-width and off-shell effects. We find that the size of the additional corrections beyond NLO can be significant and well outside of the NLO error bands given by renormalization and factorization scale variation. Applying a jet veto, we observe further negative corrections at NNLO. which we relate to the presence of large Sudakov logarithms.
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de Azcarraga, J. A., & Izquierdo, J. M. (2014). Minimal D=4 supergravity from the superMaxwell algebra. Nucl. Phys. B, 885, 34–45.
Abstract: We show that the first-order D = 4, N = 1 pure supergravity lagrangian four-form can be obtained geometrically as a quadratic expression in the curvatures of the Maxwell superalgebra. This is achieved by noticing that the relative coefficient between the two terms of the lagrangian that makes the action locally supersymmetric also determines trivial field equations for the gauge fields associated with the extra generators of the Maxwell superalgebra. Along the way, a convenient geometric procedure to check the local supersymmetry of a class of lagrangians is developed.
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Herrero-Garcia, J., Nebot, M., Rius, N., & Santamaria, A. (2014). The Zee-Babu model revisited in the light of new data. Nucl. Phys. B, 885, 542–570.
Abstract: We update previous analyses of the Zee-Babu model in the light of new data, e.g., the mixing angle On, the rare decay μ-> e gamma and the LHC results. We also analyze the possibility of accommodating the deviations in Gamma (H -> gamma gamma) hinted by the LHC experiments, and the stability of the scalar potential. We find that neutrino oscillation data and low energy constraints are still compatible with masses of the extra charged scalars accessible to LHC. Moreover, if any of them is discovered, the model can be falsified by combining the information on the singly and doubly charged scalar decay modes with neutrino data. Conversely, if the neutrino spectrum is found to be inverted and the CP phase delta is quite different from pi, the masses of the charged scalars will be well outside the LHC reach.
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Gonzalez Felipe, R., & Serodio, H. (2014). Abelian realization of phenomenological two-zero neutrino textures. Nucl. Phys. B, 886, 75–92.
Abstract: In an attempt at explaining the observed neutrino mass-squared differences and leptonic mixing, lepton mass matrices with zero textures have been widely studied. In the weak basis where the charged lepton mass matrix is diagonal, various neutrino mass matrices with two zeros have been shown to be consistent with the current experimental data. Using the canonical and Smith normal form methods, we construct the minimal Abelian symmetry realizations of these phenomenological two-zero neutrino textures. The implementation of these symmetries in the context of the seesaw mechanism for Majorana neutrino masses is also discussed.
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