Abstract: Nowadays, the options available to perform external dosimetric audits of the high dose rate (HDR) brachytherapy treatment process are limited. In this work, we present a methodology that allows for performing dosimetric audits in this field. A phantom was designed and manufactured for this purpose. The criteria for its design, together with the in-house measurements for its characterization, are presented. The result is a user-friendly system that can be mailed to perform dosimetric audits in HDR brachytherapy on-site for systems using either Iridium-192 (Ir-192) or Cobalt-60 (Co-60) sources. Objectives: The main goal of this work is to design and characterize a user-friendly methodology to perform mailed dosimetric audits in high dose rate (HDR) brachytherapy for systems using either Iridium-192 (Ir-192) or Cobalt-60 (Co-60) sources. Methods: A solid phantom was designed and manufactured with four catheters and a central slot to place one dosimeter. Irradiations with an Elekta MicroSelectron V2 for Ir-192, and with a BEBIG Multisource for Co-60 were performed for its characterization. For the dose measurements, nanoDots, a type of optically stimulated luminescent dosimeters (OSLDs), were characterized. Monte Carlo (MC) simulations were performed to evaluate the scatter conditions of the irradiation set-up and to study differences in the photon spectra of different Ir-192 sources (Microselectron V2, Flexisource, BEBIG Ir2.A85-2 and Varisource VS2000) reaching the dosimeter in the irradiation set-up. Results: MC simulations indicate that the surface material on which the phantom is supported during the irradiations does not affect the absorbed dose in the nanoDot. Generally, differences below 5% were found in the photon spectra reaching the detector when comparing the Microselectron V2, the Flexisource and the BEBIG models. However, differences up to 20% are observed between the V2 and the Varisource VS2000 models. The calibration coefficients and the uncertainty in the dose measurement were evaluated. Conclusions: The system described here is able to perform dosimetric audits in HDR brachytherapy for systems using either Ir-192 or Co-60 sources. No significant differences are observed between the photon spectra reaching the detector for the MicroSelectron V2, the Flexisource and the BEBIG Ir-192 sources. For the Varisource VS2000, a higher uncertainty is considered in the dose measurement to allow for the nanoDot response.

Abstract: We have used a density functional approach to investigate thermal homogeneous nucleation and cavitation in parahydrogen. The effect of electrons as seeds of heterogeneous cavitation in liquid parahydrogen is also discussed within the capillary model.

Abstract: The product of the A(b)(0) ((B) over bar (0)) differential production cross-section and the branching fraction of the decay A(b)(0)-> J/psi pK(-) ((B) over bar (0)-> J/psi p (K) over bar*(892)(0)) is measured as a function of the beauty hadron transverse momentum, p(T), and rapidity, y. The kinematic region of the measurements is p(T) <20 GeV/c and 2.0 < y < 4.5. The measurements use a data sample corresponding to an integrated luminosity of 3fb(-1) collected by the LHCb detector in pp collisions at centre-of-mass energies root s=7 TeV in 2011 and root s=8 TeV in 2012. Based on previous LHCb results of the fragmentation fraction ratio, f(Ab0)/f(d), the branching fraction of the decay A(b)(0)-> J/psi pK(-) is measured to be B(A(b)(0)-> J/psi pK(-))=(3.17 +/- 0.04 +/- 0.07 +/- 0.34(-0.28)(+0.45))x10(-4) where the first uncertainty is statistical, the second is systematic, the third is due to the uncertainty on the branching fraction of the decay (B) over bar (0)-> J/psi p (K) over bar*(892)(0), and the fourth is due to the knowledge of f(Ab0)/f(d). The sum of the asymmetries in the production and decay between A(b)(0) and (A) over bar (0)(b) is also measured as a function of p(T) and y. The previously published branching fraction of A(b)(0)-> J/psi p pi(-), relative to that of A(b)(0)-> J/psi pK(-), is updated. The branching fractions of A(b)(0)-> P-c(+)(-> J/psi p)K- are determined.