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KM3NeT Collaboration(Aiello, S. et al), Alves Garre, S., Calvo, D., Carretero, V., Colomer, M., Corredoira, I., et al. (2021). Architecture and performance of the KM3NeT front-end firmware. J. Astron. Telesc. Instrum. Syst., 7(1), 016001–24pp.
Abstract: The KM3NeT infrastructure consists of two deep-sea neutrino telescopes being deployed in the Mediterranean Sea. The telescopes will detect extraterrestrial and atmospheric neutrinos by means of the incident photons induced by the passage of relativistic charged particles through the seawater as a consequence of a neutrino interaction. The telescopes are configured in a three-dimensional grid of digital optical modules, each hosting 31 photomultipliers. The photomultiplier signals produced by the incident Cherenkov photons are converted into digital information consisting of the integrated pulse duration and the time at which it surpasses a chosen threshold. The digitization is done by means of time to digital converters (TDCs) embedded in the field programmable gate array of the central logic board. Subsequently, a state machine formats the acquired data for its transmission to shore. We present the architecture and performance of the front-end firmware consisting of the TDCs and the state machine.
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Carrasco-Ribelles, L. A., Pardo-Mas, J. R., Tortajada, S., Saez, C., Valdivieso, B., & Garcia-Gomez, J. M. (2021). Predicting morbidity by local similarities in multi-scale patient trajectories. J. Biomed. Inform., 120, 103837–9pp.
Abstract: Patient Trajectories (PTs) are a method of representing the temporal evolution of patients. They can include information from different sources and be used in socio-medical or clinical domains. PTs have generally been used to generate and study the most common trajectories in, for instance, the development of a disease. On the other hand, healthcare predictive models generally rely on static snapshots of patient information. Only a few works about prediction in healthcare have been found that use PTs, and therefore benefit from their temporal dimension. All of them, however, have used PTs created from single-source information. Therefore, the use of longitudinal multi-scale data to build PTs and use them to obtain predictions about health conditions is yet to be explored. Our hypothesis is that local similarities on small chunks of PTs can identify similar patients concerning their future morbidities. The objectives of this work are (1) to develop a methodology to identify local similarities between PTs before the occurrence of morbidities to predict these on new query individuals; and (2) to validate this methodology on risk prediction of cardiovascular diseases (CVD) occurrence in patients with diabetes. We have proposed a novel formal definition of PTs based on sequences of longitudinal multi-scale data. Moreover, a dynamic programming methodology to identify local alignments on PTs for predicting future morbidities is proposed. Both the proposed methodology for PT definition and the alignment algorithm are generic to be applied on any clinical domain. We validated this solution for predicting CVD in patients with diabetes and we achieved a precision of 0.33, a recall of 0.72 and a specificity of 0.38. Therefore, the proposed solution in the diabetes use case can result of utmost utility to secondary screening.
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ANTARES Collaboration(Albert, A. et al), Colomer, M., Gozzini, R., Hernandez-Rey, J. J., Illuminati, G., Khan-Chowdhury, N. R., et al. (2021). Monte Carlo simulations for the ANTARES underwater neutrino telescope. J. Cosmol. Astropart. Phys., 01(1), 064–20pp.
Abstract: Monte Carlo simulations are a unique tool to check the response of a detector and to monitor its performance. For a deep-sea neutrino telescope, the variability of the environmental conditions that can affect the behaviour of the data acquisition system must be considered, in addition to a reliable description of the active parts of the detector and of the features of physics events, in order to produce a realistic set of simulated events. In this paper, the software tools used to produce neutrino and cosmic ray signatures in the telescope and the strategy developed to represent the time evolution of the natural environment and of the detector efficiency are described.
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ANTARES Collaboration(Albert, A. et al), Carretero, V., Colomer, M., Gozzini, R., Hernandez-Rey, J. J., Illuminati, G., et al. (2021). ANTARES upper limits on the multi-TeV neutrino emission from the GRBs detected by IACTs. J. Cosmol. Astropart. Phys., 03(3), 092–17pp.
Abstract: The first gamma-ray burst detections by Imaging Atmospheric Cherenkov Telescopes have been recently announced: GRB 190114C, detected by MAGIC, GRB 180720B and GRB 190829A, observed by H.E.S.S. A dedicated search for neutrinos in space and time coincidence with the gamma-ray emission observed by IACTs has been performed using ANTARES data. The search covers both the prompt and afterglow phases, yielding no neutrinos in coincidence with the three GRBs studied. Upper limits on the energetics of the neutrino emission are inferred. The resulting upper limits are several orders of magnitude above the observed gamma-ray emission, and they do not allow to constrain the available models.
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Barenboim, G., Chen, J. Z., Hannestad, S., Oldengott, I. M., Tram, T., & Wong, Y. Y. Y. (2021). Invisible neutrino decay in precision cosmology. J. Cosmol. Astropart. Phys., 03(3), 087–53pp.
Abstract: We revisit the topic of invisible neutrino decay in the precision cosmological context, via a first-principles approach to understanding the cosmic microwave background and large-scale structure phenomenology of such a non-standard physics scenario. Assuming an effective Lagrangian in which a heavier standard-model neutrino nu(H) couples to a lighter one nu(l) and a massless scalar particle phi via a Yukawa interaction, we derive from first principles the complete set of Boltzmann equations, at both the spatially homogeneous and the firstorder inhomogeneous levels, for the phase space densities of nu(H), nu(l), and phi in the presence of the relevant decay and inverse decay processes. With this set of equations in hand, we perform a critical survey of recent works on cosmological invisible neutrino decay in both limits of decay while nu(H) is ultra-relativistic and non-relativistic. Our two main findings are: (i) in the non-relativistic limit, the effective equations of motion used to describe perturbations in the neutrino-scalar system in the existing literature formally violate momentum conservation and gauge invariance, and (ii) in the ultra-relativistic limit, exponential damping of the anisotropic stress does not occur at the commonly-used rate Gamma(T) = (1/tau(0))( m(nu H)/E-nu H)(3), but at a rate similar to (1/ tau(0))(m(nu H)/E-nu H)(5). Both results are model-independent. The impact of the former finding on the cosmology of invisible neutrino decay is likely small. The latter, however, implies a significant revision of the cosmological limit on the neutrino lifetime tau(0) from tau(old)(0) greater than or similar to 1.2 x 10(9) s (m(nu H)/50 meV)(3) to tau(0) greater than or similar to (4 x 10(5) -> 4 x 10(6)) s (m(nu H)/50 meV)(5).
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