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Author |
Piersanti, L.; Bellini, F.; Bini, F.; Collamati, F.; De Lucia, E.; Durante, M.; Faccini, R.; Ferroni, F.; Fiore, S.; Iarocci, E.; La Tessa, C.; Marafini, M.; Mattei, I.; Patera, V.; Ortega, P.G.; Sarti, A.; Schuy, C.; Sciubba, A.; Vanstalle, M.; Voena, C. |
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Title |
Measurement of charged particle yields from PMMA irradiated by a 220 MeV/u C-12 beam |
Type |
Journal Article |
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Year |
2014 |
Publication  |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
59 |
Issue |
7 |
Pages |
1857-1872 |
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Keywords |
drift chamber; LYSO; hadrontherapy; carbon ion beam; dose monitoring |
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Abstract |
The radiation used in hadrontherapy treatments interacts with the patient body producing secondary particles, either neutral or charged, that can be used for dose and Bragg peak monitoring and to provide a fast feedback on the treatment plans. Recent results obtained from the authors on simplified setups (mono-energetic primary beams interacting with homogeneous tissue like target) have already indicated the correlation that exists between the flux of these secondaries coming from the target (e.g. protons and photons) and the position of the primary beam Bragg peak. In this paper, the measurements of charged particle fluxes produced by the interaction of a 220 MeV/u carbon ion beam at GSI, Darmstadt, with a polymethyl methacrylate target are reported. The emission region of protons (p), deuterons (d) and tritons (t) has been characterized using a drift chamber while the particle time-of-flight, used to compute the kinetic energy spectra, was measured with a LYSO scintillator.The energy released in the LYSO crystal was used for particle identification purposes. The measurements were repeated with the setup at 60 degrees and 90 degrees with respect to the primary beam direction. The accuracy on the fragments emission profile reconstruction and its relationship with the Bragg peak position have been studied. Based on the acquired experimental evidence, a method to monitor the dose profile and the position of the Bragg peak inside the target is proposed. |
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Address |
[Piersanti, L.; De Lucia, E.; Iarocci, E.; Mattei, I.; Sarti, A.] Ist Nazl Fis Nucl, Lab Nazl Frascati, I-00044 Frascati, Italy, Email: vincenzo.patera@lnf.infn.it |
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Publisher |
Iop Publishing Ltd |
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English |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000333186200020 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1735 |
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Author |
Muñoz, E.; Barrio, J.; Etxebeste, A.; Ortega, P.G.; Lacasta, C.; Oliver, J.F.; Solaz, C.; Llosa, G. |
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Title |
Performance evaluation of MACACO: a multilayer Compton camera |
Type |
Journal Article |
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Year |
2017 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
62 |
Issue |
18 |
Pages |
7321-7341 |
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Keywords |
Compton imaging; Compton camera; continuous LaBr3 crystal; silicon photomultiplier; hadron therapy |
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Abstract |
Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm. |
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Address |
[Munoz, Enrique; Barrio, John; Etxebeste, Ane; Ortega, Pablo G.; Lacasta, Carlos; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es |
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Publisher |
Iop Publishing Ltd |
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English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000408229900003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3253 |
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Author |
Muñoz, E.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F. |
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Title |
A spectral reconstruction algorithm for two-plane Compton cameras |
Type |
Journal Article |
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Year |
2020 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
65 |
Issue |
2 |
Pages |
025011 - 17pp |
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Keywords |
Compton imaging; Compton camera; hadron therapy; image reconstruction |
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Abstract |
One factor limiting the current applicability extent of hadron therapy is the lack of a reliable method for real time treatment monitoring. The use of Compton imaging systems as monitors requires the correct reconstruction of the distribution of prompt gamma productions during patient irradiation. In order to extract the maximum information from all the measurable events, we implemented a spectral reconstruction method that assigns to all events a probability of being either partial or total energy depositions. The method, implemented in a list-mode maximum likelihood expectation maximization algorithm, generates a four dimensional image in the joint spatial-spectral domain, in which the voxels containing the emission positions and energies are obtained. The analytical model used for the system response function is also employed to derive an analytical expression for the sensitivity, which is calculated via Monte Carlo integration. The performance of the method is evaluated through reconstruction of various experimental and simulated sources with different spatial and energy distributions. The results show that the proposed method can recover the spectral and spatial information simultaneously, but only under the assumption of ideal measurements. The analysis of the Monte Carlo simulations has led to the identification of two important degradation sources: the mispositioning of the gamma interaction point and the missing energy recorded in the interaction. Both factors are related to the high energy transferred to the recoil electrons, which can travel far from the interaction point and even escape the detector. These effects prevent the direct application of the current method in more realistic scenarios. Nevertheless, experimental point-like sources have been accurately reconstructed and the spatial distributions and spectral emission of complex simulated phantoms can be identified. |
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Address |
[Munoz, Enrique; Barrientos, Luis; Bernabeu, Jose; Borja-Lloret, Marina; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es |
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Corporate Author |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000520111400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
4332 |
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| Permanent link to this record |
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Author |
Roser, J.; Muñoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J.F. |
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Title |
Image reconstruction for a multi-layer Compton telescope: an analytical model for three interaction events |
Type |
Journal Article |
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Year |
2020 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
65 |
Issue |
14 |
Pages |
145005 - 17pp |
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Keywords |
Compton camera; Compton imaging; hadron therapy; image reconstruction; lm-mlem; monte carlo simulations; multi-layer Compton telescope |
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Abstract |
Compton Cameras are electronically collimated photon imagers suitable for sub-MeV to few MeV gamma-ray detection. Such features are desirable to enablein vivorange verification in hadron therapy, through the detection of secondary Prompt Gammas. A major concern with this technique is the poor image quality obtained when the incoming gamma-ray energy is unknown. Compton Cameras with more than two detector planes (multi-layer Compton Cameras) have been proposed as a solution, given that these devices incorporate more signal sequences of interactions to the conventional two interaction events. In particular, three interaction events convey more spectral information as they allow inferring directly the incident gamma-ray energy. A three-layer Compton Telescope based on continuous Lanthanum (III) Bromide crystals coupled to Silicon Photomultipliers is being developed at the IRIS group of IFIC-Valencia. In a previous work we proposed a spectral reconstruction algorithm for two interaction events based on an analytical model for the formation of the signal. To fully exploit the capabilities of our prototype, we present here an extension of the model for three interaction events. Analytical expressions of the sensitivity and the System Matrix are derived and validated against Monte Carlo simulations. Implemented in a List Mode Maximum Likelihood Expectation Maximization algorithm, the proposed model allows us to obtain four-dimensional (energy and position) images by using exclusively three interaction events. We are able to recover the correct spectrum and spatial distribution of gamma-ray sources when ideal data are employed. However, the uncertainties associated to experimental measurements result in a degradation when real data from complex structures are employed. Incorrect estimation of the incident gamma-ray interaction positions, and missing deposited energy associated with escaping secondaries, have been identified as the causes of such degradation by means of a detailed Monte Carlo study. As expected, our current experimental resolution and efficiency to three interaction events prevents us from correctly recovering complex structures of radioactive sources. However, given the better spectral information conveyed by three interaction events, we expect an improvement of the image quality of conventional Compton imaging when including such events. In this regard, future development includes the incorporation of the model assessed in this work to the two interaction events model in order to allow using simultaneously two and three interaction events in the image reconstruction. |
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Address |
[Roser, J.; Munoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J. F.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: Jorge.Roser@ific.uv.es |
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Corporate Author |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000552701600001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
4481 |
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| Permanent link to this record |
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Author |
Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Muñoz, E.; Ros, A.; Viegas, R.; Llosa, G. |
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Title |
Joint image reconstruction algorithm in Compton cameras |
Type |
Journal Article |
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Year |
2022 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
67 |
Issue |
15 |
Pages |
155009 - 15pp |
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Keywords |
Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope |
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Abstract |
Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging. |
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Address |
[Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Munoz, E.; Ros, A.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Jorge.Roser@ific.uv.es |
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Corporate Author |
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Thesis |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000827830200001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5298 |
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| Permanent link to this record |
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Author |
Barrientos, L.; Borja-Lloret, M.; Casaña, J.V.; Dendooven, P.; Garcia Lopez, J.G.; Hueso-Gonzalez, F.; Jiméeez-Ramos, M.C.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G. |
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Title |
Gamma-ray sources imaging and test-beam results with MACACO III Compton camera |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physica Medica |
Abbreviated Journal |
Phys. Medica |
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Volume |
117 |
Issue |
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Pages |
103199 - 10pp |
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Keywords |
Hadron therapy; Compton camera; Scintillator crystals; Silicon photomultipliers |
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Abstract |
Hadron therapy is a radiotherapy modality which offers a precise energy deposition to the tumors and a dose reduction to healthy tissue as compared to conventional methods. However, methods for real-time monitoring are required to ensure that the radiation dose is deposited on the target. The IRIS group of IFIC-Valencia developed a Compton camera prototype for this purpose, intending to image the Prompt Gammas emitted by the tissue during irradiation. The system detectors are composed of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. After an initial characterization in the laboratory, in order to assess the system capabilities for future experiments in proton therapy centers, different tests were carried out in two facilities: PARTREC (Groningen, The Netherlands) and the CNA cyclotron (Sevilla, Spain). Characterization studies performed at PARTREC indicated that the detectors linearity was improved with respect to the previous version and an energy resolution of 5.2 % FWHM at 511 keV was achieved. Moreover, the imaging capabilities of the system were evaluated with a line source of 68Ge and a point-like source of 241Am-9Be. Images at 4.439 MeV were obtained from irradiation of a graphite target with an 18 MeV proton beam at CNA, to perform a study of the system potential to detect shifts at different intensities. In this sense, the system was able to distinguish 1 mm variations in the target position at different beam current intensities for measurement times of 1800 and 600 s. |
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Address |
[Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Perez-Curbelo, J.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es |
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Corporate Author |
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Thesis |
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Publisher |
Elsevier Sci Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1120-1797 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001145147400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5892 |
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| Permanent link to this record |
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Author |
Ferreira, M.N.; Papavassiliou, J. |
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Title |
Gauge Sector Dynamics in QCD |
Type |
Journal Article |
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Year |
2023 |
Publication |
Particles |
Abbreviated Journal |
Particles |
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Volume |
6 |
Issue |
1 |
Pages |
312-363 |
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Keywords |
continuum Schwinger function methods; emergence of hadron mass; gluon mass generation; lattice QCD; non-perturbative quantum field theory; quantum chromodynamics; Schwinger-Dyson equations; Schwinger mechanism |
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Abstract |
The dynamics of the QCD gauge sector give rise to non-perturbative phenomena that are crucial for the internal consistency of the theory; most notably, they account for the generation of a gluon mass through the action of the Schwinger mechanism, the taming of the Landau pole, the ensuing stabilization of the gauge coupling, and the infrared suppression of the three-gluon vertex. In the present work, we review some key advances in the ongoing investigation of this sector within the framework of the continuum Schwinger function methods, supplemented by results obtained from lattice simulations. |
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Address |
[Ferreira, Mauricio Narciso; Papavassiliou, Joannis] Univ Valencia, Dept Theoret Phys, E-46100 Valencia, Spain, Email: ansonar@uv.es; |
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Corporate Author |
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Thesis |
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Publisher |
Mdpi |
Place of Publication |
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Language |
English |
Summary Language |
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Expedition |
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Conference |
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Notes |
WOS:000959126400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5504 |
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| Permanent link to this record |
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Author |
Vijande, J.; Valcarce, A.; Carames, T.F.; Garcilazo, H. |
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Title |
Heavy hadron spectroscopy: A quark model perspective |
Type |
Journal Article |
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Year |
2013 |
Publication |
Nuclear Physics A |
Abbreviated Journal |
Nucl. Phys. A |
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Volume |
914 |
Issue |
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Pages |
472-481 |
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Keywords |
Heavy hadrons; Constituent quark model; Many-quark systems |
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Abstract |
We present recent results of hadron spectroscopy and hadron-hadron interaction from the perspective of constituent quark models. We pay special attention to the role played by higher order Fock space components in the hadron spectra and the connection of this extension with the hadron-hadron interaction. The main goal of our description is to obtain a coherent understanding of the low-energy hadron phenomenology without enforcing any particular model, to constrain its characteristics and learn about low-energy realization of the theory. |
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Address |
[Vijande, J.] UV, Dept Fis Atom Mol & Nucl, Valencia, Spain, Email: javier.vijande@uv.es |
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Corporate Author |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0375-9474 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000324847700067 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1599 |
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| Permanent link to this record |
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Author |
Lutz, M.F.M. et al; Nieves, J. |
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Title |
Resonances in QCD |
Type |
Journal Article |
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Year |
2016 |
Publication |
Nuclear Physics A |
Abbreviated Journal |
Nucl. Phys. A |
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Volume |
948 |
Issue |
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Pages |
93-105 |
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Keywords |
Mini review; Resonances; Hadrons; QCD |
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Abstract |
We report on the EMMI Rapid Reaction Task Force meeting 'Resonances in QCD', which took place at GSI October 12-14,2015. A group of 26 people met to discuss the physics of resonances in QCD. The aim of the meeting was defined by the following three key questions: What is needed to understand the physics of resonances in QCD? Where does QCD lead us to expect resonances with exotic quantum numbers? What experimental efforts are required to arrive at a coherent picture? For light mesons and baryons only those with up, down and strange quark content were considered. For heavy-light and heavy-heavy meson systems, those with charm quarks were the focus. This document summarizes the discussions by the participants, which in turn led to the coherent conclusions we present here. |
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Address |
[Lutz, Matthias F. M.] GSI Helmholtzzentrum Schwerionenforsch GmbH, D-64291 Darmstadt, Germany, Email: m.lutz@gsi.de; |
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Publisher |
Elsevier Science Bv |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0375-9474 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000372943100007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2599 |
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| Permanent link to this record |
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Author |
ATLAS Collaboration (Aaboud, M. et al); Alvarez Piqueras, D.; Barranco Navarro, L.; Cabrera Urban, S.; Castillo Gimenez, V.; Cerda Alberich, L.; Costa, M.J.; Escobar, C.; Estrada Pastor, O.; Fernandez Martinez, P.; Ferrer, A.; Fiorini, L.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Higon-Rodriguez, E.; Jimenez Pena, J.; Lacasta, C.; Mamuzic, J.; Marti-Garcia, S.; Melini, D.; Mitsou, V.A.; Pedraza Lopez, S.; Rodriguez Bosca, S.; Rodriguez Rodriguez, D.; Romero Adam, E.; Salt, J.; Sanchez Martinez, V.; Soldevila, U.; Sanchez, J.; Valero, A.; Valls Ferrer, J.A.; Vos, M. |
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Title |
Measurement of jet fragmentation in 5.02 TeV proton-lead and proton-proton collisions with the ATLAS detector |
Type |
Journal Article |
| |
Year |
2018 |
Publication |
Nuclear Physics A |
Abbreviated Journal |
Nucl. Phys. A |
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Volume |
978 |
Issue |
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Pages |
65-106 |
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Keywords |
Relativistic heavy-ion collisions; Jets; Fragmentation into hadrons |
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Abstract |
A measurement of the fragmentation functions of jets into charged particles in p Pb collisions and pp collisions is presented. The analysis utilizes 28 nb(-1) of p Pb data and 26 pb(-1) of pp data, both at root(TN)-T-s= 5.02 TeV, collected in 2013 and 2015, respectively, with the ATLAS detector at the LHC. The measurement is reported in the centre-of-mass frame of the nucleon-nucleon system for jets in the rapidity range vertical bar y*vertical bar <1.6 and with transverse momentum 45 < p(T) < 260 GeV. Results are presented both as a function of the charged-particle transverse momentum and as a function of the longitudinal momentum fraction of the particle with respect to the jet. The pp fragmentation functions are compared with results from Monte Carlo event generators and two theoretical models. The ratios of the p +Pb to pp fragmentation functions are found to be consistent with unity. (C) 2018 CERN for the benefit of the ATLAS Collaboration. |
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Address |
[Jackson, P.; Petridis, A.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia |
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Elsevier Science Bv |
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Language |
English |
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ISSN |
0375-9474 |
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Notes |
WOS:000446948800005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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IFIC @ pastor @ |
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3761 |
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