Abstract: The use of Compton cameras for medical imaging and its interest as a hadron therapy treatment monitoring has increased in the last decade with the development of silicon photomultipliers. MACACOp is a Compton camera prototype designed and assembled at the IRIS group of IFIC-Valencia. This Compton camera is based on monolithic Lanthanum (III) Bromide crystals and silicon photomultipliers, and employs the novel TOFPET2 ASIC as readout electronics. This system emerged as an alternative to MACACO II prototype, with the aim of improving its limited time resolution. To test the performance of the ASIC in a Compton camera setup, the prototype was characterized, both in laboratory and in-beam. A time resolution of 1.5 ns was obtained after time corrections, which improves greatly the performance of the MACACO II. Moreover, the results obtained at high photon energies demonstrate the ability of the system to obtain 1 mm displacements of the reconstructed spots. The results reinforce the potential of the system as a monitoring device for hadron therapy.

Abstract: The exploration of the universe has recently entered a new era thanks to the multi-messenger paradigm, characterized by a continuous increase in the quantity and quality of experimental data that is obtained by the detection of the various cosmic messengers (photons, neutrinos, cosmic rays and gravitational waves) from numerous origins. They give us information about their sources in the universe and the properties of the intergalactic medium. Moreover, multi-messenger astronomy opens up the possibility to search for phenomenological signatures of quantum gravity. On the one hand, the most energetic events allow us to test our physical theories at energy regimes which are not directly accessible in accelerators; on the other hand, tiny effects in the propagation of very high energy particles could be amplified by cosmological distances. After decades of merely theoretical investigations, the possibility of obtaining phenomenological indications of Planck-scale effects is a revolutionary step in the quest for a quantum theory of gravity, but it requires cooperation between different communities of physicists (both theoretical and experimental). This review, prepared within the COST Action CA18108 “Quantum gravity phenomenology in the multi-messenger approach”, is aimed at promoting this cooperation by giving a state-of-the art account of the interdisciplinary expertise that is needed in the effective search of quantum gravity footprints in the production, propagation and detection of cosmic messengers.

Abstract: A data sample collected with the LHCb detector corresponding to an integrated luminosity of 9 fb(-1) is used to measure eleven CP violation observables in B-+/- -> Dh(+/-) decays, where h is either a kaon or a pion. The neutral D meson decay is reconstructed in the three-body final states: K-+/-pi(-/+)pi(0); pi(+)pi(-)pi(0); K+ K- pi(0) and the suppressed pi K-+(-/+)pi(0) combination. The mode where a large CP asymmetry is expected, B-+/- -> [K-+/-pi(-/+)pi(0)] K-D(+/-), is observed with a significance greater than seven standard deviations. The ratio of the partial width of this mode relative to that of the favoured mode, B-+/- -> [K-+/-pi(-/+)pi(0)] K-D(+/-), is R-ADS(K) = (1.27 +/- 0.16 +/- 0.02) x 10(-2). Evidence for a large CP asymmetry is also seen: A(ADS(K)) = – 0.38 +/- 0.12 +/- 0.02. Constraints on the CKM angle gamma are calculated from the eleven reported observables.