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Author Aguiar, P.; Rafecas, M.; Ortuño, J.E.; Kontaxakis, G.; Santos, A.; Pavia, J.; Rosetti, M.
Title Geometrical and Monte Carlo projectors in 3D PET reconstruction Type Journal Article
Year 2010 Publication Medical Physics Abbreviated Journal Med. Phys.
Volume 37 Issue 11 Pages 5691-5702
Keywords 3D PET; iterative reconstruction; list-mode reconstruction; ray-tracing techniques; Monte Carlo simulation; system response matrix
Abstract Purpose: In the present work, the authors compare geometrical and Monte Carlo projectors in detail. The geometrical projectors considered were the conventional geometrical Siddon ray-tracer (S-RT) and the orthogonal distance-based ray-tracer (OD-RT), based on computing the orthogonal distance from the center of image voxel to the line-of-response. A comparison of these geometrical projectors was performed using different point spread function (PSF) models. The Monte Carlo-based method under consideration involves an extensive model of the system response matrix based on Monte Carlo simulations and is computed off-line and stored on disk. Methods: Comparisons were performed using simulated and experimental data of the commercial small animal PET scanner rPET. Results: The results demonstrate that the orthogonal distance-based ray-tracer and Siddon ray-tracer using PSF image-space convolutions yield better images in terms of contrast and spatial resolution than those obtained after using the conventional method and the multiray-based S-RT. Furthermore, the Monte Carlo-based method yields slight improvements in terms of contrast and spatial resolution with respect to these geometrical projectors. Conclusions: The orthogonal distance-based ray-tracer and Siddon ray-tracer using PSF image-space convolutions represent satisfactory alternatives to factorizing the system matrix or to the conventional on-the-fly ray-tracing methods for list-mode reconstruction, where an extensive modeling based on Monte Carlo simulations is unfeasible.
Address [Aguiar, Pablo] Univ Santiago de Compostela, Dept Fis Particulas, Complexo Hosp Univ Santiago de Compostela, Fdn IDICHUS IDIS, Santiago De Compostela, Spain, Email: pablo.aguiar.fernandez@sergas.es
Corporate Author Thesis
Publisher Amer Assoc Physicists Medicine Amer Inst Physics Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes (up) ISI:000283747600015 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ elepoucu @ Serial 338
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Author Fernandes, L.M.P.; Freitas, E.D.C.; Ball, M.; Gomez-Cadenas, J.J.; Monteiro, C.M.B.; Yahlali, N.; Nygren, D.; dos Santos, J.M.F.
Title Primary and secondary scintillation measurements in a Xenon Gas Proportional Scintillation Counter Type Journal Article
Year 2010 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 5 Issue Pages P09006 - 15pp
Keywords Interaction of radiation with matter; Gaseous detectors; Photon detectors for UV, visible and IR photons (vacuum) (photomultipliers, HPDs, others)
Abstract NEXT is a new experiment to search for neutrinoless double beta decay using a 100 kg radio-pure high-pressure gaseous xenon TPC. The detector requires excellent energy resolution, which can be achieved in a Xe TPC with electroluminescence readout. Hamamatsu R8520-06SEL photomultipliers are good candidates for the scintillation readout. The performance of this photomultiplier, used as VUV photosensor in a gas proportional scintillation counter, was investigated. Initial results for the detection of primary and secondary scintillation produced as a result of the interaction of 5.9 keV X-rays in gaseous xenon, at room temperature and at pressures up to 3 bar, are presented. An energy resolution of 8.0% was obtained for secondary scintillation produced by 5.9 keV X-rays. No significant variation of the primary scintillation was observed for different pressures (1, 2 and 3 bar) and for electric fields up to 0.8 V cm(-1) torr(-1) in the drift region, demonstrating negligible recombination luminescence. A primary scintillation yield of 81 +/- 7 photons was obtained for 5.9 keV X-rays, corresponding to a mean energy of 72 +/- 6 eV to produce a primary scintillation photon in xenon.
Address [Fernandes, L. M. P.; Freitas, E. D. C.; Monteiro, C. M. B.; dos Santos, J. M. F.] Univ Coimbra, Dept Phys, Instrumentat Ctr, P-3004516 Coimbra, Portugal, Email: pancho@gian.fis.uc.pt
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes (up) ISI:000283796100003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 255
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Author Garonna, A.; Amaldi, U.; Bonomi, R.; Campo, D.; Degiovanni, A.; Garlasche, M.; Mondino, I.; Rizzoglio, V.; Verdu-Andres, S.
Title Cyclinac medical accelerators using pulsed C6+/H-2(+) ion sources Type Journal Article
Year 2010 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 5 Issue Pages C09004 - 19pp
Keywords Instrumentation for particle-beam therapy; Instrumentation for hadron therapy; Ion sources (positive ions, negative ions, electron cyclotron resonance (ECR), electron beam (EBIS)); Acceleration cavities and magnets superconducting (high-temperature superconductor; radiation hardened magnets; normal-conducting; permanent magnet devices; wigglers and undulators)
Abstract Charged particle therapy, or so-called hadrontherapy, is developing very rapidly. There is large pressure on the scientific community to deliver dedicated accelerators, providing the best possible treatment modalities at the lowest cost. In this context, the Italian research Foundation TERA is developing fast-cycling accelerators, dubbed 'cyclinacs'. These are a combination of a cyclotron (accelerating ions to a fixed initial energy) followed by a high gradient linac boosting the ions energy up to the maximum needed for medical therapy. The linac is powered by many independently controlled klystrons to vary the beam energy from one pulse to the next. This accelerator is best suited to treat moving organs with a 4D multipainting spot scanning technique. A dual proton/carbon ion cyclinac is here presented. It consists of an Electron Beam Ion Source, a superconducting isochronous cyclotron and a high-gradient linac. All these machines are pulsed at high repetition rate (100-400 Hz). The source should deliver both C6+ and H-2(+) ions in short pulses (1.5 μs flat-top) and with sufficient intensity (at least 10(8) fully stripped carbon ions per pulse at 300 Hz). The cyclotron accelerates the ions to 120 MeV/u. It features a compact design (with superconducting coils) and a low power consumption. The linac has a novel C-band high-gradient structure and accelerates the ions to variable energies up to 400 MeV/u. High RF frequencies lead to power consumptions which are much lower than the ones of synchrotrons for the same ion extraction energy. This work is part of a collaboration with the CLIC group, which is working at CERN on high-gradient electron-positron colliders.
Address [Garonna, A.; Amaldi, U.; Bonomi, R.; Campo, D.; Degiovanni, A.; Garlasche, M.; Mondino, I.; Rizzoglio, V.; Andres, S. Verdu] TERA Fdn, I-28100 Novara, Italy, Email: Adriano.Garonna@cern.ch
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes (up) ISI:000283796100011 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 327
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Author Blume, M.; Martinez-Moller, A.; Keil, A.; Navab, N.; Rafecas, M.
Title Joint Reconstruction of Image and Motion in Gated Positron Emission Tomography Type Journal Article
Year 2010 Publication IEEE Transactions on Medical Imaging Abbreviated Journal IEEE Trans. Med. Imaging
Volume 29 Issue 11 Pages 1892-1906
Keywords Gating; motion compensation; positron emission tomography (PET); reconstruction
Abstract We present a novel intrinsic method for joint reconstruction of both image and motion in positron emission tomography (PET). Intrinsic motion compensation methods exclusively work on the measured data, without any external motion measurements. Most of these methods separate image from motion estimation: They use deformable image registration/optical flow techniques in order to estimate the motion from individually reconstructed gates. Then, the image is estimated based on this motion information. With these methods, a main problem lies in the motion estimation step, which is based on the noisy gated frames. The more noise is present, the more inaccurate the image registration becomes. As we show both visually and quantitatively, joint reconstruction using a simple deformation field motion model can compete with state-of-the-art image registration methods which use robust multilevel B-spline motion models.
Address [Blume, Moritz; Rafecas, Magdalena] Univ Valencia, CSIC, IFIC, E-46071 Valencia, Spain, Email: moritz.blume@cs.tum.edu
Corporate Author Thesis
Publisher Ieee-Inst Electrical Electronics Engineers Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0278-0062 ISBN Medium
Area Expedition Conference
Notes (up) ISI:000283941800007 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 340
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Author NEMO-3 Collaboration (Argyriades, J. et al); Martin-Albo, J.; Novella, P.
Title Measurement of the two neutrino double beta decay half-life of Zr-96 with the NEMO-3 detector Type Journal Article
Year 2010 Publication Nuclear Physics A Abbreviated Journal Nucl. Phys. A
Volume 847 Issue 3-4 Pages 168-179
Keywords RADIOACTIVITY Zr-96(2 beta); measured E-beta,E- E-gamma, beta beta-, beta gamma-coin; deduced T-1/2 for 2 nu beta beta-decay, NEMO-3 detector
Abstract Using 9.4 g of Zr-96 isotope and 1221 days of data from the NEMO-3 detector corresponding (0 0.031 kg y, the obtained 2 nu beta beta decay half-life measurement is T-1/2(2 nu) = [2.35 +/- 0.14(stat) +/- 0.16(syst)] x 10(19) yr. Different characteristics of the final state electrons have been studied, such as the energy sum, individual electron energy, and angular distribution. The 2v nuclear matrix element is extracted using the measured 2 nu beta beta half-life and is M-2 nu = 0.049 +/- 0.002. Constraints on 0 nu beta beta decay have also been set.
Address [Basharina-Freshville, A.; Chapon, A.; Daraktchieva, Z.; Flack, R.; Kauer, M.; King, S.; Saakyan, R.; Thomas, J.; Vasiliev, V.] UCL, London WC1E 6BT, England, Email: kauer@hep.ucl.ac.uk
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0375-9474 ISBN Medium
Area Expedition Conference
Notes (up) ISI:000283955700003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 337
Permanent link to this record