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Penas, J., Alejo, A., Bembibre, A., Apiñaniz, J. I., Garcia-Garcia, E., Guerrero, C., et al. (2024). Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source. Sci Rep, 14(1), 11448–12pp.
Abstract: Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.
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Bout, R., Busto, J., Cecchini, V., Charpentier, P., Chapellier, M., Dastgheibi-Fard, A., et al. (2024). Perspectives of a single-anode cylindrical chamber operating in ionization mode and high gas pressure. Eur. Phys. J. C, 84(5), 512–14pp.
Abstract: As part of the R2D2 (Rare Decays with Radial Detector) R &D, the use of a gas detector with a spherical or cylindrical cathode, equipped with a single anode and operating at high pressure, was studied for the search of rare phenomena such as neutrinoless double-beta decay. The presented measurements were obtained with a cylindrical detector, covering gas pressures ranging from 1 to 10 bar in argon and 1 to 6 bar in xenon, using both a point-like source of 210 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{210} $$\end{document} Po (5.3 MeV alpha \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha $$\end{document} ) and a diffuse source of 222 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{222}$$\end{document} Rn (5.5 MeV alpha \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\alpha $$\end{document} ). Analysis and interpretation of the data were developed using the anodic current waveform. Similar detection performances were achieved with both gases, and comparable energy resolutions were measured with both sources. As long as the purity of the gas was sufficient, no significant degradation of the measured energy was observed by increasing the pressure. At the highest operating pressure, an energy resolution better than 1.5% full-width at half-maximum (FWHM) was obtained for both gaseous media, although optimal noise conditions were not reached.
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Wang, D., & Mena, O. (2024). Robust analysis of the growth of structure. Phys. Rev. D, 109(8), 083539–18pp.
Abstract: Current cosmological tensions show that it is crucial to test the predictions from the canonical ACDM paradigm at different cosmic times. One very appealing test of structure formation in the Universe is the growth rate of structure in our universe f, usually parametrized via the growth index gamma, with f equivalent to Omega(m)(a)gamma and gamma similar or equal to 0.55 in the standard ACDM case. Recent studies have claimed a suppression of the growth of structure from a variety of cosmological observations, characterized by gamma > 0.55. By employing different self-consistent growth parametrizations schemes, we show here that gamma < 0.55, obtaining instead an enhanced growth of structure today. This preference reaches the 3 sigma significance using cosmic microwave background observations, supernova Ia and baryon acoustic oscillation measurements. The addition of cosmic microwave background lensing data relaxes such a preference to the 2 sigma level, since a larger lensing effect can always be compensated with a smaller structure growth, or, equivalently, with gamma > 0.55. We have also included the lensing amplitude AL as a free parameter in our data analysis, showing that the preference for AL > 1 still remains, except for some particular parametrizations when lensing observations are included. We also do not find any significant preference for an oscillatory dependence of AL, AL + Am sin l. To further reassess the effects of a nonstandard growth, we have computed by means of N-body simulations the dark matter density fields, the dark matter halo mass functions and the halo density profiles for different values of gamma. Future observations from the Square Kilometer Array, reducing by a factor of 3 the current errors on the gamma parameter, further confirm or refute with a strong statistical significance the deviation of the growth index from its standard value.
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Gil-Dominguez, F., & Molina, R. (2024). Quark mass dependence of the D*s0 (2317) and D s1 (2460) resonances. Phys. Rev. D, 109(9), 096002–17pp.
Abstract: We determine the quark mass dependence-light and heavy-of the D*s0(2317) and Ds1(2460) properties, such as, mass, coupling to D(*)K, scattering lengths and compositeness, from a global analysis I = 0 for different boosts and two pion masses. The formalism is based in the local hidden-gauge interaction of Weinberg-Tomozawa type which respects both chiral and heavy quark spin symmetries, supplemented by a term that takes into account the D(*)K coupling to a bare cs<overline> component. The isospin violating decay of the D*s0(2317) -> D+s pi 0 is also evaluated.
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Roca, L., Song, J., & Oset, E. (2024). Molecular pentaquarks with hidden charm and double strangeness. Phys. Rev. D, 109(9), 094005–8pp.
Abstract: We analyze theoretically the coupled-channel meson-baryon interaction with global flavor c<overline>cssn and c<overline>csss, where mesons are pseudoscalars or vectors, and baryons have JP = 1/2+ or 3/2+. The aim is to explore whether the nonlinear dynamics inherent in the unitarization process within coupled channels can dynamically generate double- and triple-strange pentaquark-type states (Pcss and Pcsss, respectively), for which there is no experimental evidence to date. We evaluate the s-wave scattering matrix by implementing unitarity in coupled channels, using potential kernels obtained from t-channel vector meson exchange. The required PPV and VVV vertices are obtained from Lagrangians derived through appropriate extensions of the local hidden gauge symmetry approach to the charm sector, while capitalizing on the symmetry of the spin and flavor wave function to evaluate the BBV vertex. We find four different poles in the double strange sector, some of them degenerate in spin. For the triple-strange channel, we find the meson-baryon interaction insufficient to generate a bound or resonance state through the unitary coupled-channel dynamics.
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