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Author |
Torres-Espallardo, I.; Diblen, F.; Rohling, H.; Solevi, P.; Gillam, J.; Watts, D.; Espana, S.; Vandenberghe, S.; Fiedler, F.; Rafecas, M. |
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Title |
Evaluation of resistive-plate-chamber-based TOF-PET applied to in-beam particle therapy monitoring |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
9 |
Pages |
N187-N208 |
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Keywords |
PET; in-beam; RPC; particle therapy; TOF; range deviation; partial-ring |
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Abstract |
Particle therapy is a highly conformal radiotherapy technique which reduces the dose deposited to the surrounding normal tissues. In order to fully exploit its advantages, treatment monitoring is necessary to minimize uncertainties related to the dose delivery. Up to now, the only clinically feasible technique for the monitoring of therapeutic irradiation with particle beams is Positron Emission Tomography (PET). In this work we have compared a Resistive Plate Chamber (RPC)-based PET scanner with a scintillation-crystal-based PET scanner for this application. In general, the main advantages of the RPC-PET system are its excellent timing resolution, low cost, and the possibility of building large area systems. We simulated a partial-ring scannerbeam monitoring, which has an intrinsically low positron yield compared to diagnostic PET. In addition, for in-beam PET there is a further data loss due to the partial ring configuration. In order to improve the performance of the RPC-based scanner, an improved version of the RPC detector (modifying the thickness of the gas and glass layers), providing a larger sensitivity, has been simulated and compared with an axially extended version of the crystal-based device. The improved version of the RPC shows better performance than the prototype, but the extended version of the crystal-based PET outperforms all other options. based on an RPC prototype under construction within the Fondazione per Adroterapia Oncologica (TERA). For comparison with the crystal-based PET scanner we have chosen the geometry of a commercially available PET scanner, the Philips Gemini TF. The coincidence time resolution used in the simulations takes into account the current achievable values as well as expected improvements of both technologies. Several scenarios (including patient data) have been simulated to evaluate the performance of different scanners. Initial results have shown that the low sensitivity of the RPC hampers its application to hadron |
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Address |
[Torres-Espallardo, I.; Solevi, P.; Gillam, J.; Rafecas, M.] UV, CSIC, Inst Fis Corpuscular IFIC, E-46071 Valencia, Spain, Email: irene.torres@uv.es |
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Publisher |
Iop Publishing Ltd |
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English |
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ISSN |
0031-9155 |
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Notes  |
WOS:000354104700003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2227 |
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Author |
Cabello, J.; Etxebeste, A.; Llosa, G.; Ziegler, S.I. |
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Title |
Simulation study of PET detector limitations using continuous crystals |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
60 |
Issue |
9 |
Pages |
3673-3694 |
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Keywords |
continuous crystals; parallax effects; depth of interaction; high resolution; small animal PET |
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Abstract |
Continuous crystals can potentially obtain better intrinsic detector spatial resolution compared to pixelated crystals, additionally providing depth of interaction (DoI) information from the light distribution. To achieve high performance sophisticated interaction position estimation algorithms are required. There are a number of algorithms in the literature applied to different crystal dimensions and different photodetectors. However, the different crystal properties and photodetector array geometries have an impact on the algorithm performance. In this work we analysed, through Monte Carlo simulations, different combinations of realistic crystals and photodetector parameters to better understand their influence on the interaction position estimation accuracy, with special emphasis on the DoI. We used an interaction position estimation based on an analytical model for the present work. Different photodetector granulation schemes were investigated. The impact of the number of crystal faces readout by photodetectors was studied by simulating scenarios with one and two photodetectors. In addition, crystals with different levels of reflection and aspect ratios (AR) were analysed. Results showed that the impact of photodetector granularity is mainly shown near the edges and specially in the corners of the crystal. The resulting intrinsic spatial resolution near the centre with a 12 x 12 x 10 mm(3) LYSO crystal was 0.7-0.9 mm, while the average spatial resolution calculated on the entire crystal was 0.77 +/- 0.18 mm for all the simulated geometries with one and two photodetectors. Having front and back photodetectors reduced the DoI bias (Euclidean distance between estimated DoI and real DoI) and improved the transversal resolution near the corners. In scenarios with one photodetector, small AR resulted in DoI inaccuracies for absorbed events at the entrance of the crystal. These inaccuracies were slightly reduced either by increasing the AR or reducing the amount of reflected light, and highly mitigated using two photodetectors. Using one photodetector, we obtained a piecewise DoI error model with a DoI resolution of 0.4-0.9 mm for a 1.2 AR crystal, and we observed that including a second photodetector or reducing the amount of reflections reduced the DoI bias but did not significantly improve the DoI resolution. Translating the piecewise DoI error model obtained in this study to image reconstruction we obtained a spatial resolution variability of 0.39 mm using 85% of the FoV, compared to 2.59 mm and 1.87 mm without DoI correction or with a dual layer system, respectively. |
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Address |
[Cabello, Jorge; Ziegler, Sibylle I.] Tech Univ Munich, Klinikum Rechts Isar, Nukl Med Klin & Poliklin, D-80290 Munich, Germany, Email: jorge.cabello@tum.de |
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Iop Publishing Ltd |
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English |
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ISSN |
0031-9155 |
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Notes |
WOS:000354104700019 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2226 |
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Author |
Lorusso, G. et al; Montaner-Piza, A. |
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Title |
beta-Decay Half-Lives of 110 Neutron-Rich Nuclei across the N=82 Shell Gap: Implications for the Mechanism and Universality of the Astrophysical r Process |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
114 |
Issue |
19 |
Pages |
192501 - 7pp |
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Keywords |
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Abstract |
The beta-decay half-lives of 110 neutron-rich isotopes of the elements from 37 Rb to 50 Sn were measured at the Radioactive Isotope Beam Factory. The 40 new half-lives follow robust systematics and highlight the persistence of shell effects. The new data have direct implications for r-process calculations and reinforce the notion that the second (A approximate to 130) and the rare-earth-element (A approximate to 160) abundance peaks may result from the freeze-out of an (n, gamma) reversible arrow (gamma, n) equilibrium. In such an equilibrium, the new half-lives are important factors determining the abundance of rare-earth elements, and allow for a more reliable discussion of the r process universality. It is anticipated that universality may not extend to the elements Sn, Sb, I, and Cs, making the detection of these elements in metal-poor stars of the utmost importance to determine the exact conditions of individual r-process events. |
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Address |
[Lorusso, G.; Nishimura, S.; Xu, Z. Y.; Shimizu, Y.; Soederstroem, P. -A.; Watanabe, H.; Browne, F.; Doornenbal, P.; Gey, G.; Taprogge, J.; Vajta, Zs.; Wu, J.; Baba, H.; Fukuda, N.; Inabe, N.; Isobe, T.; Kameda, D.; Kubo, T.; Sakurai, H.; Schury, P.; Suzuki, H.; Takeda, H.] RIKEN, Nishina Ctr, Wako, Saitama 3510198, Japan |
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Publisher |
Amer Physical Soc |
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English |
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ISSN |
0031-9007 |
ISBN |
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Conference |
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Notes |
WOS:000354347300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2224 |
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Author |
Dai, L.R.; Xie, J.J.; Oset, E. |
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Title |
Study of the f(2)(1270), f '(2)(1525), and (K)over-bar(2)*(1430), f(0)(1370) and f(0)(1710) production from psi(nS) and Upsilon(nS) decays |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
91 |
Issue |
9 |
Pages |
094013 - 6pp |
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Keywords |
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Abstract |
Based on previous studies that support the important role of the f(2)(1270), f'(2)(1525), and (K) over bar (2)*(1430) resonances in the J/psi[psi(2S)] -> phi(omega)VV decays, we make an analysis of the analogous decays of Upsilon(1S) and Upsilon(2S), taking into account recent experimental data. In addition, we study the J/psi and psi(2S) radiative decays and we also made predictions for the radiative decay of Upsilon(1S) and Upsilon(2S) into gamma f(2)(1270), gamma f(2)'(1525), gamma f(0)(1370) and gamma f(0)(1710) comparing with the recent results of a CLEO experiment. We can compare our results for ratios of decay rates with eight experimental ratios and find agreement in all but one case, where experimental problems are discussed. |
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Address |
[Dai, Lian-Rong] Liaoning Normal Univ, Dept Phys, Dalian 116029, Peoples R China, Email: xiejujun@impcas.ac.cn |
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Publisher |
Amer Physical Soc |
Place of Publication |
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English |
Summary Language |
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Series Volume |
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ISSN |
1550-7998 |
ISBN |
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Notes |
WOS:000354367900003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2223 |
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Author |
Bambi, C.; Olmo, G.J.; Rubiera-Garcia, D. |
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Title |
Melvin universe in Born-Infeld gravity |
Type |
Journal Article |
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Year |
2015 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
91 |
Issue |
10 |
Pages |
104010 - 6pp |
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Keywords |
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Abstract |
We consider a magnetic flux pointing in the z direction of an axially symmetric space-time (Melvin universe) in a Born-Infeld-type extension of general relativity (GR) formulated in the Palatini approach. Large magnetic fields could have been produced in the early Universe, and given rise to interesting phenomenology regarding wormholes and black hole remnants. We find a formal analytic solution to this problem that recovers the GR result in the appropriate limits. Our results set the basis for further extensions that could allow the embedding of pairs of black hole remnants in geometries with intense magnetic fields. |
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Address |
[Bambi, Cosimo; Rubiera-Garcia, D.] Fudan Univ, Ctr Field Theory & Particle Phys, Shanghai 200433, Peoples R China, Email: bambi@fudan.edu.cn; |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Conference |
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Notes |
WOS:000354368000004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2222 |
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