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Author |
Granero, D.; Candela-Juan, C.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Jacob, D.; Mourtada, F. |
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Title |
Technical Note: Dosimetry of Leipzig and Valencia applicators without the plastic cap |
Type |
Journal Article |
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Year |
2016 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
43 |
Issue |
5 |
Pages |
2087 - 4pp |
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Keywords |
Leipzig applicators; Valencia applicators; skin brachytherapy; Monte Carlo; dosimetry |
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Abstract |
Purpose: High dose rate (HDR) brachytherapy for treatment of small skin lesions using the Leipzig and Valencia applicators is a widely used technique. These applicators are equipped with an attachable plastic cap to be placed during fraction delivery to ensure electronic equilibrium and to prevent secondary electrons from reaching the skin surface. The purpose of this study is to report on the dosimetric impact of the cap being absent during HDR fraction delivery, which has not been explored previously in the literature. Methods: GEANT4 Monte Carlo simulations (version 10.0) have been performed for the Leipzig and Valencia applicators with and without the plastic cap. In order to validate the Monte Carlo simulations, experimental measurements using radiochromic films have been done. Results: Dose absorbed within 1 mm of the skin surface increases by a factor of 1500% for the Leipzig applicators and of 180% for the Valencia applicators. Deeper than 1 mm, the overdosage flattens up to a 10% increase. Conclusions: Differences of treating with or without the plastic cap are significant. Users must check always that the plastic cap is in place before any treatment in order to avoid overdosage of the skin. Prior to skin HDR fraction delivery, the timeout checklist should include verification of the cap placement. (C) 2016 American Association of Physicists in Medicine. |
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Address |
[Granero, D.] Hosp Gen Univ, Dept Radiat Phys, ERESA, Valencia 46014, Spain, Email: dgranero@eresa.com |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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ISSN |
0094-2405 |
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Notes |
WOS:000378924200010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2753 |
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Permanent link to this record |
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Author |
de Salas, P.F.; Pastor, S. |
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Title |
Relic neutrino decoupling with flavour oscillations revisited |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
07 |
Issue |
7 |
Pages |
051 - 18pp |
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Keywords |
cosmological neutrinos; particle physics – cosmology connection; physics of the; early universe; neutrino properties |
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Abstract |
We study the decoupling process of neutrinos in the early universe in the presence of three-flavour oscillations. The evolution of the neutrino spectra is found by solving the corresponding momentum-dependent kinetic equations for the neutrino density matrix, including for the first time the proper collision integrals for both diagonal and off-diagonal elements. This improved calculation modifies the evolution of the off-diagonal elements of the neutrino density matrix and changes the deviation from equilibrium of the frozen neutrino spectra. However, it does not vary the contribution of neutrinos to the cosmological energy density in the form of radiation, usually expressed in terms of the effective number of neutrinos, N-eff. We find a value of N-eff = 3.045, in agreement with previous theoretical calculations and consistent with the latest analysis of Planck data. This result does not depend on the ordering of neutrino masses. We also consider the effect of non-standard neutrino-electron interactions (NSI), predicted in many theoretical models where neutrinos acquire mass. For two sets of NSI parameters allowed by present data, we find that Neff can be reduced down to 3.040 or enhanced up to 3.059. |
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Address |
[de Salas, Pablo F.; Pastor, Sergio] Univ Valencia, CSIC, Inst Fis Corpuscular, Parc Cient UV,C Catedrat Jose Beltran 2, E-46980 Paterna, Valencia, Spain, Email: pabrerde@ific.uv.es; |
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Publisher |
Iop Publishing Ltd |
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English |
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ISSN |
1475-7516 |
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Notes |
WOS:000381830000052 |
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no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2784 |
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Permanent link to this record |
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Author |
Llosa, G.; Trovato, M.; Barrio, J.; Etxebeste, A.; Muñoz, E.; Lacasta, C.; Oliver, J.F.; Rafecas, M.; Solaz, C.; Solevi, P. |
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Title |
First Images of a Three-layer compton Telescope prototype for Treatment Monitoring in hadron Therapy |
Type |
Journal Article |
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Year |
2016 |
Publication |
Frontiers in Oncology |
Abbreviated Journal |
Front. Oncol. |
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Volume |
6 |
Issue |
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Pages |
14 - 6pp |
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Keywords |
Compton camera; Compton telescope; hadron therapy; treatment monitoring; LaBr3 |
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Abstract |
A Compton telescope for dose monitoring in hadron therapy is under development at IFIC. The system consists of three layers of LaBr3 crystals coupled to silicon photomulti-plier arrays. Na-22 sources have been successfully imaged reconstructing the data with an ML-EM code. Calibration and temperature stabilization are necessary for the prototype operation at low coincidence rates. A spatial resolution of 7.8 mm FWHM has been obtained in the first imaging tests. |
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Address |
[Llosa, Gabriela; Trovato, Marco; Barrio, John; Etxebeste, Ane; Munoz, Enrique; Lacasta, Carlos; Oliver, Josep F.; Rafecas, Magdalena; Solaz, Carles; Solevi, Paola] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: gabriela.llosa@ific.uv.es |
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Publisher |
Frontiers Media Sa |
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English |
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Edition |
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ISSN |
2234-943x |
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Notes |
WOS:000369799800001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ elepoucu @ |
Serial |
2785 |
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Permanent link to this record |
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Author |
Hernandez, P.; Kekic, M.; Lopez-Pavon, J.; Racker, J.; Salvado, J. |
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Title |
Testable baryogenesis is in seesaw models |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of High Energy Physics |
Abbreviated Journal |
J. High Energy Phys. |
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Volume |
08 |
Issue |
8 |
Pages |
157 - 29pp |
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Keywords |
Cosmology of Theories beyond the SM; CP violation; Neutrino Physics; Beyond Standard Model |
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Abstract |
We revisit the production of baryon asymmetries in the minimal type I seesaw model with heavy Majorana singlets in the GeV range. In particular we include “washout” effects from scattering processes with gauge bosons, Higgs decays and inverse decays, besides the dominant top scatterings. We show that in the minimal model with two singlets, and for an inverted light neutrino ordering, future measurements from SHiP and neutrinoless double beta decay could in principle provide sufficient information to predict the matter-antimatter asymmetry in the universe. We also show that SHiP measurements could provide very valuable information on the PMNS CP phases. |
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Address |
[Hernandez, P.; Kekic, M.; Racker, J.; Salvado, J.] Univ Valencia, Inst Fis Corpuscular, Edificio Inst Invest,Catedrat Jose Beltran 2, Valencia 46980, Spain, Email: m.pilar.hernandez@uv.es; |
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Publisher |
Springer |
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Language |
English |
Summary Language |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1029-8479 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000382398000004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2787 |
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Permanent link to this record |
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Author |
Oset, E.; Chen, H.X.; Feijoo, A.; Geng, L.S.; Liang, W.H.; Li, D.M.; Lu, J.X.; Magas, V.K.; Nieves, J.; Ramos, A.; Roca, L.; Wang, E.; Xie, J.J. |
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Title |
Study of reactions disclosing hidden charm pentaquarks with or without strangeness |
Type |
Journal Article |
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Year |
2016 |
Publication |
Nuclear Physics A |
Abbreviated Journal |
Nucl. Phys. A |
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Volume |
954 |
Issue |
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Pages |
371-392 |
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Keywords |
Pentaquark reactions; Molecular states with hidden charm |
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Abstract |
We present results for five reactions, Lambda(b) -> J/psi K(-)p, Lambda(b) -> J/psi eta Lambda, Lambda(b) -> J/psi pi(-)p, Lambda(b) -> J/psi K-0 Lambda and Xi(-)(b) -> J/psi K-Lambda, where combining information from the meson baryon interaction, using the chiral unitary approach, and predictions made for molecular states of hidden charm, with or without strangeness, we can evaluate invariant mass distributions for the light meson baryon states, and for those of J/psi p or J/psi Lambda. We show that with the present available information, in all of these reactions one finds peaks where the pentaquark states show up. In the Lambda(b) -> J/psi K(-)p, and Lambda(b) -> J/psi pi(-)p reactions we show that the results obtained from our study are compatible with present experimental observations. |
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Address |
[Oset, Eulogio] Univ Valencia, Ctr Mixto, CSIC, Inst Invest Paterna,Dept Fis Teor, Aptdo 22085, E-46071 Valencia, Spain, Email: oset@ific.uv.es |
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Publisher |
Elsevier Science Bv |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0375-9474 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000381331200025 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2791 |
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Permanent link to this record |
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Author |
n_TOF Collaboration (Cosentino, L. et al); Domingo-Pardo, C.; Tain, J.L.; Tarifeño-Saldivia, A. |
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Title |
Experimental setup and procedure for the measurement of the Be-7(n,alpha)alpha reaction at n_TOF |
Type |
Journal Article |
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Year |
2016 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
830 |
Issue |
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Pages |
197-205 |
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Keywords |
Cosmological lithium problem; Big bang nucleosynthesis; Be-7(n,alpha)alpha reaction; n_TOF spallation neutron source |
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Abstract |
The newly built second experimental area EAR2 of then n_ToF spallation neutron source at CERN allows to perform (n, charged particles) experiments on short-lived highly radioactive targets. This paper describes a detection apparatus and the experimental procedure for the determination of the cross-section of the Be-7(n,alpha)alpha reaction, which represents one of the focal points toward the solution of the cosmological Lithium abundance problem, and whose only measurement, at thermal energy, dates back to 1963. The apparently unsurmountable experimental difficulties stemming from the huge Be-7 gamma-activity, along with the lack of a suitable neutron beam facility, had so far prevented further measurements. The detection system is subject to considerable radiation damage, but is capable of disentangling the rare reaction signals from the very high background. This newly developed setup could likely be useful also to study other challenging reactions requiring the detectors to be installed directly in the neutron beam. |
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Address |
[Cosentino, L.; Musumarra, A.; Pappalardo, A.; Piscopo, M.; Finocchiaro, P.; Cardella, R.; Heyse, J.; Jenkins, D. G.; Kaeppeler, F.; Katabuchi, T.; Kokkoris, M.; Lederer, C.; Lonsdale, S.; Massimi, C.; Mastinu, P.; Matteucci, F.; Mazzone, A.; Milazzo, P. M.; Nolte, R.; Patronis, N.; Pavlik, A.; Rauscher, T.; Schillebeeckx, P.; Stamatopoulos, A.; Tsinganis, A.; Vannini, G.; Vlastou, R.; Wallner, A.; Woods, P. J.] INFN Lab Nazl Sud, Catania, Italy, Email: FINOCCHIARO@LNS.INFN.IT |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000381530300027 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2792 |
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Permanent link to this record |
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Author |
Ancilotto, F.; Barranco, M.; Navarro, J.; Pi, M. |
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Title |
A Density Functional Approach to Para-hydrogen at Zero Temperature |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Low Temperature Physics |
Abbreviated Journal |
J. Low Temp. Phys. |
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Volume |
185 |
Issue |
1-2 |
Pages |
26-38 |
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Keywords |
Solid and liquid bulk para-hydrogen; Small para-hydrogen clusters; Density functional theory |
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Abstract |
We have developed a density functional (DF) built so as to reproduce either the metastable liquid or the solid equation of state of bulk para-hydrogen, as derived from quantum Monte Carlo zero temperature calculations. As an application, we have used it to study the structure and energetics of small para-hydrogen clusters made of up to molecules. We compare our results for liquid clusters with diffusion Monte Carlo (DMC) calculations and find a fair agreement between them. In particular, the transition found within DMC between hollow-core structures for small N values and center-filled structures at higher N values is reproduced. The present DF approach yields results for (pH) clusters indicating that for small N values a liquid-like character of the clusters prevails, while solid-like clusters are instead energetically favored for . |
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Address |
[Ancilotto, Francesco] Dipartimento Fis & Astron Galileo Galilei, Padua, Italy, Email: manuel@ecm.ub.edu |
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Publisher |
Springer/Plenum Publishers |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0022-2291 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000382142000003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2814 |
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Permanent link to this record |
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Author |
Gimenez-Alventosa, V.; Vijande, J.; Ballester, F.; Perez-Calatayud, J. |
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Title |
Transit dose comparisons for Co-60 and Ir-192 HDR sources |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Radiological Protection |
Abbreviated Journal |
J. Radiol. Prot. |
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Volume |
36 |
Issue |
4 |
Pages |
858-864 |
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Keywords |
Monte Carlo; dosimetry; HDR brachytherapy; transit dose |
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Abstract |
The goal of this study is to evaluate the ambient dose due to the transit of high dose rate (HDR) Co-60 sources along a transfer tube as compared to Ir-192 ones in a realistic clinical scenario. This goal is accomplished by evaluating air-kerma differences with Monte Carlo calculations using PENELOPE2011. Scatter from both the afterloader and the patient was not taken into account. Two sources, mHDR-v2 and Flexisource Co-60, (Elekta Brachytherapy, Veenendaal, the Netherlands) have been considered. These sources were simulated within a standard transfer tube located in an infinite air phantom. The movement of the source was included by displacing their positions along the connecting tube from z = – 75 cm to z = + 75 cm and combining them. Since modern afterloaders like Flexitron (Elekta) or Saginova (BEBIG GmbH) are able to use equally 192Ir and 60Co sources, it was assumed that both sources are displaced with equal speed. Typical HDR source activity content values were provided by the manufacturer. 2D distributions were obtained with type-A uncertainties (k = 2) less than 0.01%. From those, the air-kerma ratio Co-60/Ir-192 was evaluated weighted by their corresponding typical activities. It was found that it varies slowly with distance (less than 10% variation at 75 cm) but strongly in time due to the shorter half-life of the 192Ir (73.83 d). The maximum ratio is located close to the tube. It reaches a value of 0.57 when the typical activity of the sources at the time when they were installed by the vendor was used. Such ratio increases up to 1.28 at the end of the recommended working life (90 d) of the Ir-192 source. Co-60/Ir-192 air-kerma ratios are almost constant (0.51-0.57) in the vicinity of the source-tube with recent installed sources. Nevertheless, air-kerma ratios increase rapidly (1.15-1.29) whenever the Ir-192 is approaching the end of its life. In case of a medical event requiring the medical staff to access the treatment room, these ratios indicate that the dosimetric impact on the medical team will be lower, with a few exceptions, in the case of Co-60-based HDR brachytherapy as compared to Ir-192-based one when typical air-kerma strength values are considered. |
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Address |
[Gimenez-Alventosa, Vicent; Vijande, Javier; Ballester, Facundo] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: javier.vijande@uv.es |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Issue |
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Edition |
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ISSN |
0952-4746 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000386436100002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2839 |
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Permanent link to this record |
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Author |
Trbojevich, R.A.; Fernandez, A.; Watanabe, F.; Mustafa, T.; Bryant, M.S. |
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Title |
Comparative study of silver nanoparticle permeation using Side-Bi-Side and Franz diffusion cells |
Type |
Journal Article |
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Year |
2016 |
Publication |
Journal of Nanoparticle Research |
Abbreviated Journal |
J. Nanopart. Res. |
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Volume |
18 |
Issue |
3 |
Pages |
55 - 12pp |
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Keywords |
Membranes; Silver nanoparticles; Diffusion cells; Food packaging; Permeation; Environmental and health effects |
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Abstract |
Better understanding the mechanisms of nanoparticle permeation through membranes and packaging polymers has important implications for the evaluation of drug transdermal uptake, in food safety and the environmental implications of nanotechnology. In this study, permeation of 21 nm diameter silver nanoparticles (AgNPs) was tested using Side-Bi-Side and Franz static diffusion cells through hydrophilic 0.1 and 0.05 lm pore diameter 125 μm thick synthetic cellulose membranes, and 16 and 120 μm thick low-density polyethylene (LDPE) films. Experiments performed with LDPE films discarded permeation of AgNPs or Ag ions over the investigated time-frame in both diffusion systems. But controlled release of AgNPs has been quantified using semipermeable hydrophilic membranes. The permeation followed a quasi-linear time-dependent model during the experimental time-frame, which represents surface reaction-limited permeation. Diffusive flux, diffusion coefficients, and membrane permeability were determined as a function of pore size and diffusion model. Concentration gradient and pore size were key to understand mass transfer phenomena in the diffusion systems. |
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Address |
[Trbojevich, Raul A.; Bryant, Matthew S.] US FDA, Div Biochem Toxicol, Natl Ctr Toxicol Res, 3900 NCTR Rd, Jefferson, AR 72079 USA, Email: velifdez@ific.uv.es |
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Publisher |
Springer |
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Language |
English |
Summary Language |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1388-0764 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000387044400002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2849 |
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Permanent link to this record |
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Author |
Alekhin, S. et al; Hernandez, P. |
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Title |
A facility to search for hidden particles at the CERN SPS: the SHiP physics case |
Type |
Journal Article |
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Year |
2016 |
Publication |
Reports on Progress in Physics |
Abbreviated Journal |
Rep. Prog. Phys. |
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Volume |
79 |
Issue |
12 |
Pages |
124201 - 137pp |
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Keywords |
beyond the standard model physics; intensity frontier experiment; hidden sectors; heavy neutral leptons; dark photons |
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Abstract |
This paper describes the physics case for a new fixed target facility at CERN SPS. The SHiP (search for hidden particles) experiment is intended to hunt for new physics in the largely unexplored domain of very weakly interacting particles with masses below the Fermi scale, inaccessible to the LHC experiments, and to study tau neutrino physics. The same proton beam setup can be used later to look for decays of tau-leptons with lepton flavour number non-conservation, tau -> 3 μand to search for weakly-interacting sub-GeV dark matter candidates. We discuss the evidence for physics beyond the standard model and describe interactions between new particles and four different portals-scalars, vectors, fermions or axion-like particles. We discuss motivations for different models, manifesting themselves via these interactions, and how they can be probed with the SHiP experiment and present several case studies. The prospects to search for relatively light SUSY and composite particles at SHiP are also discussed. We demonstrate that the SHiP experiment has a unique potential to discover new physics and can directly probe a number of solutions of beyond the standard model puzzles, such as neutrino masses, baryon asymmetry of the Universe, dark matter, and inflation. |
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Address |
[Alekhin, Sergey] DESY, Platanenallee 6, D-15738 Zeuthen, Germany, Email: oleg.ruchayskiy@cern.ch |
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Publisher |
Iop Publishing Ltd |
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English |
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Series Issue |
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Edition |
|
|
|
ISSN |
0034-4885 |
ISBN |
|
Medium |
|
|
|
Area |
|
Expedition |
|
Conference |
|
|
|
Notes |
WOS:000387025400001 |
Approved |
no |
|
|
Is ISI |
yes |
International Collaboration |
yes |
|
|
Call Number |
IFIC @ pastor @ |
Serial |
2852 |
|
Permanent link to this record |