Ma, Y. Z., Vijande, J., Ballester, F., Tedgren, A. C., Granero, D., Haworth, A., et al. (2017). A generic TG-186 shielded applicator for commissioning model-based dose calculation algorithms for high-dose-rate Ir-192 brachytherapy. Med. Phys., 44(11), 5961–5976.
Abstract: PurposeA joint working group was created by the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) with the charge, among others, to develop a set of well-defined test case plans and perform calculations and comparisons with model-based dose calculation algorithms (MBDCAs). Its main goal is to facilitate a smooth transition from the AAPM Task Group No. 43 (TG-43) dose calculation formalism, widely being used in clinical practice for brachytherapy, to the one proposed by Task Group No. 186 (TG-186) for MBDCAs. To do so, in this work a hypothetical, generic high-dose rate (HDR) Ir-192 shielded applicator has been designed and benchmarked. MethodsA generic HDR Ir-192 shielded applicator was designed based on three commercially available gynecological applicators as well as a virtual cubic water phantom that can be imported into any DICOM-RT compatible treatment planning system (TPS). The absorbed dose distribution around the applicator with the TG-186 Ir-192 source located at one dwell position at its center was computed using two commercial TPSs incorporating MBDCAs (Oncentra((R)) Brachy with Advanced Collapsed-cone Engine, ACE, and BrachyVision ACUROS) and state-of-the-art Monte Carlo (MC) codes, including ALGEBRA, BrachyDose, egs_brachy, Geant4, MCNP6, and Penelope2008. TPS-based volumetric dose distributions for the previously reported source centered in water and source displaced test cases, and the new source centered in applicator test case, were analyzed here using the MCNP6 dose distribution as a reference. Volumetric dose comparisons of TPS results against results for the other MC codes were also performed. Distributions of local and global dose difference ratios are reported. ResultsThe local dose differences among MC codes are comparable to the statistical uncertainties of the reference datasets for the source centered in water and source displaced test cases and for the clinically relevant part of the unshielded volume in the source centered in applicator case. Larger local differences appear in the shielded volume or at large distances. Considering clinically relevant regions, global dose differences are smaller than the local ones. The most disadvantageous case for the MBDCAs is the one including the shielded applicator. In this case, ACUROS agrees with MC within [-4.2%, +4.2%] for the majority of voxels (95%) while presenting dose differences within [-0.12%, +0.12%] of the dose at a clinically relevant reference point. For ACE, 95% of the total volume presents differences with respect to MC in the range [-1.7%, +0.4%] of the dose at the reference point. ConclusionsThe combination of the generic source and generic shielded applicator, together with the previously developed test cases and reference datasets (available in the Brachytherapy Source Registry), lay a solid foundation in supporting uniform commissioning procedures and direct comparisons among treatment planning systems for HDR Ir-192 brachytherapy.
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NEXT Collaboration(Azevedo, C. D. R. et al), Gomez-Cadenas, J. J., Alvarez, V., Benlloch-Rodriguez, J. M., Botas, A., Carcel, S., et al. (2018). Microscopic simulation of xenon-based optical TPCs in the presence of molecular additives. Nucl. Instrum. Methods Phys. Res. A, 877, 157–172.
Abstract: We introduce a simulation framework for the transport of high and low energy electrons in xenon-based optical time projection chambers (OTPCs). The simulation relies on elementary cross sections (electron-atom and electron-molecule) and incorporates, in order to compute the gas scintillation, the reaction/quenching rates (atom-atom and atom-molecule) of the first 41 excited states of xenon and the relevant associated excimers, together with their radiative cascade. The results compare positively with observations made in pure xenon and its mixtures with CO2 and CF4 in a range of pressures from 0.1 to 10 bar. This work sheds some light on the elementary processes responsible for the primary and secondary xenon-scintillation mechanisms in the presence of additives, that are of interest to the OTPC technology.
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Bejarano, C., Lobo, F. S. N., Olmo, G. J., & Rubiera-Garcia, D. (2017). Palatini wormholes and energy conditions from the prism of general relativity. Eur. Phys. J. C, 77(11), 776–13pp.
Abstract: Wormholes are hypothetical shortcuts in space-time that in general relativity unavoidably violate all of the pointwise energy conditions. In this paper, we consider several wormhole spacetimes that, as opposed to the standard designer procedure frequently employed in the literature, arise directly from gravitational actions including additional terms resulting from contractions of the Ricci tensor with the metric, and which are formulated assuming independence between metric and connection (Palatini approach). We reinterpret such wormhole solutions under the prism of General Relativity and study the matter sources that thread them. We discuss the size of violation of the energy conditions in different cases and how this is related to the same spacetimes when viewed from the modified gravity side.
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T2K Collaboration(Abe, K. et al), Cervera-Villanueva, A., Izmaylov, A., & Novella, P. (2017). Measurement of neutrino and antineutrino oscillations by the T2K experiment including a new additional sample of nu(e) interactions at the far detector. Phys. Rev. D, 96(9), 092006–49pp.
Abstract: The T2K experiment reports an updated analysis of neutrino and antineutrino oscillations in appearance and disappearance channels. A sample of electron neutrino candidates at Super-Kamiokande in which a pion decay has been tagged is added to the four single-ring samples used in previous T2K oscillation analyses. Through combined analyses of these five samples, simultaneous measurements of four oscillation parameters, vertical bar Delta m(32)(2)vertical bar, sin(2) theta(23), sin(2) theta(13), and delta(CP) and of the mass ordering are made. A set of studies of simulated data indicates that the sensitivity to the oscillation parameters is not limited by neutrino interaction model uncertainty. Multiple oscillation analyses are performed, and frequentist and Bayesian intervals are presented for combinations of the oscillation parameters with and without the inclusion of reactor constraints on sin(2) theta(13). When combined with reactor measurements, the hypothesis of CP conservation (delta(CP) = 0 or pi) is excluded at 90% confidence level. The 90% confidence region for delta(CP) is [-2.95, -0.44] ([-1.47, -1.27]) for normal (inverted) ordering. The central values and 68% confidence intervals for the other oscillation parameters for normal (inverted) ordering are Delta m(32)(2) = 2.54 +/- 0.08(2.51 +/- 0.08) x 10(-3) eV(2)/c(4) and sin(2) theta(23) = 0.55(-0.09)(+0.005) (0.55(-0.08)(+0.05)), compatible with maximal mixing. In the Bayesian analysis, the data weakly prefer normal ordering (Bayes factor 3.7) and the upper octant for sin(2) theta(23) (Bayes factor 2.4).
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Hiller Blin, A. N. (2017). Systematic study of octet-baryon electromagnetic form factors in covariant chiral perturbation theory. Phys. Rev. D, 96(9), 093008–19pp.
Abstract: We perform a complete and systematic calculation of the octet-baryon form factors within the fully covariant approach of SU(3) chiral perturbation theory at O(p(3)). We use the extended on-mass shell renormalization scheme and include explicitly the vector mesons and the spin-3/2 decuplet intermediate states. Comparing these predictions with data including magnetic moments, charges, and magnetic radii, we determine the unknown low-energy constants and give predictions for yet unmeasured observables, such as the magnetic moment of the Sigma(0) and the charge and magnetic radii of the hyperons.
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