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Peppa, V., Thomson, R. M., Enger, S. A., Fonseca, G. P., Lee, C. N., Lucero, J. N. E., et al. (2023). A MC-based anthropomorphic test case for commissioning model-based dose calculation in interstitial breast 192-Ir HDR brachytherapy. Med. Phys., 50(7), 4675–4687.
Abstract: PurposeTo provide the first clinical test case for commissioning of Ir-192 brachytherapy model-based dose calculation algorithms (MBDCAs) according to the AAPM TG-186 report workflow. Acquisition and Validation MethodsA computational patient phantom model was generated from a clinical multi-catheter Ir-192 HDR breast brachytherapy case. Regions of interest (ROIs) were contoured and digitized on the patient CT images and the model was written to a series of DICOM CT images using MATLAB. The model was imported into two commercial treatment planning systems (TPSs) currently incorporating an MBDCA. Identical treatment plans were prepared using a generic Ir-192 HDR source and the TG-43-based algorithm of each TPS. This was followed by dose to medium in medium calculations using the MBDCA option of each TPS. Monte Carlo (MC) simulation was performed in the model using three different codes and information parsed from the treatment plan exported in DICOM radiation therapy (RT) format. Results were found to agree within statistical uncertainty and the dataset with the lowest uncertainty was assigned as the reference MC dose distribution. Data Format and Usage NotesThe dataset is available online at ,. Files include the treatment plan for each TPS in DICOM RT format, reference MC dose data in RT Dose format, as well as a guide for database users and all files necessary to repeat the MC simulations. Potential ApplicationsThe dataset facilitates the commissioning of brachytherapy MBDCAs using TPS embedded tools and establishes a methodology for the development of future clinical test cases. It is also useful to non-MBDCA adopters for intercomparing MBDCAs and exploring their benefits and limitations, as well as to brachytherapy researchers in need of a dosimetric and/or a DICOM RT information parsing benchmark. Limitations include specificity in terms of radionuclide, source model, clinical scenario, and MBDCA version used for its preparation.
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Gimenez-Alventosa, V., Ballester, F., & Vijande, J. (2016). VoxelMages: a general-purpose graphical interface for designing geometries and processing DICOM images for PENELOPE. Appl. Radiat. Isot., 118, 251–257.
Abstract: The design and construction of geometries for Monte Carlo calculations is an error-prone, time-consuming, and complex step in simulations describing particle interactions and transport in the field of medical physics. The software VoxelMages has been developed to help the user in this task. It allows to design complex geometries and to process DICOM image files for simulations with the general-purpose Monte Carlo code PENELOPE in an easy and straightforward way. VoxelMages also allows to import DICOM-RT structure contour information as delivered by a treatment planning system. Its main characteristics, usage and performance benchmarking are described in detail.
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Fernandez-Carames, T., Valcarce, A., & Vijande, J. (2010). Charged charmonium molecules. Phys. Rev. D, 82(5), 054032–5pp.
Abstract: We make use of a self-consistent quark-model based study of four-quark charmonium-like states to interpret recent charmonium experimental data. We conclude that there exists a D*(D) over bar* meson-meson molecule with quantum numbers (I-G) J(PC) = (1(-))2(++). Our study confirms the presence of charged charmonium-like resonances on the excited charmonium spectrum. We find support from recent experimental data by the Belle Collaboration [R. Mizuk et al. (Belle Collaboration), Phys. Rev. D 78, 072004 (2008)]. Confirmation of the experimental data by the Belle Collaboration and the determination of the quantum numbers of the new structures would help in discriminating among different theoretical models and would give further support to the theoretical analysis of T. Fernandez-Carames, A. Valcarce, and J. Vijande [Phys. Rev. Lett. 103, 222001 (2009)].
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Vijande, J., Valcarce, A., & Richard, J. M. (2012). Stability of hexaquarks in the string limit of confinement. Phys. Rev. D, 85(1), 014019–6pp.
Abstract: The stability of systems containing six quarks or antiquarks is studied within a simple string model inspired by the strong-coupling regime of quantum chromodynamics and used previously for tetraquarks and pentaquarks. We discuss both six-quark (q(6)) and three-quark-three-antiquark (q(3)($) over bar (3)) states. The quarks are assumed to be distinguishable and thus not submitted to antisymmetrization. It is found that the ground state of (q(6)) is stable against dissociation into two isolated baryons. For the case of (q(3)($) over bar (3)), our results indicate the existence of a bound state very close to the threshold. The investigations are extended to (q(3)Q(3)) and (Q(3) ($) over bar (3)) systems with two different constituent masses, and their stability is discussed as a function of the mass ratio.
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Carames, T. F., Valcarce, A., & Vijande, J. (2012). Too many X's, Y's and Z's? Phys. Lett. B, 709(4-5), 358–361.
Abstract: A large number of new states have been reported during the last few years in charmonium spectroscopy above the charmed meson production threshold. They have been called X's, Y's, and Z's. We reflect on the influence of thresholds on heavy meson spectroscopy comparing different flavor sectors and quantum numbers. The validity of a quark-model picture above open-flavor thresholds would severely restrict the number of channels that may lodge meson-meson molecules.
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