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Author Etxebeste, A.; Dauvergne, D.; Fontana, M.; Letang, J.M.; Llosa, G.; Muñoz, E.; Oliver, J.F.; Testa, E.; Sarrut, D.
Title CCMod: a GATE module for Compton camera imaging simulation Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue 5 Pages 055004 - 17pp
Keywords (down) Monte Carlo; simulation; gamma imaging; Compton camera
Abstract Compton cameras are gamma-ray imaging systems which have been proposed for a wide variety of applications such as medical imaging, nuclear decommissioning or homeland security. In the design and optimization of such a system Monte Carlo simulations play an essential role. In this work, we propose a generic module to perform Monte Carlo simulations and analyses of Compton Camera imaging which is included in the open-source GATE/Geant4 platform. Several digitization stages have been implemented within the module to mimic the performance of the most commonly employed detectors (e.g. monolithic blocks, pixelated scintillator crystals, strip detectors...). Time coincidence sorter and sequence coincidence reconstruction are also available in order to aim at providing modules to facilitate the comparison and reproduction of the data taken with different prototypes. All processing steps may be performed during the simulation (on-the-fly mode) or as a post-process of the output files (offline mode). The predictions of the module have been compared with experimental data in terms of energy spectra, angular resolution, efficiency and back-projection image reconstruction. Consistent results within a 3-sigma interval were obtained for the energy spectra except for low energies where small differences arise. The angular resolution measure for incident photons of 1275 keV was also in good agreement between both data sets with a value close to 13 degrees. Moreover, with the aim of demonstrating the versatility of such a tool the performance of two different Compton camera designs was evaluated and compared.
Address [Etxebeste, A.; Letang, J. M.; Sarrut, D.] Univ Lyon 1, Univ Lyon, CREATIS, CNRS UMR5220,Inserm U1044,INSA Lyon, Lyon, France, Email: ane.etxebeste@creatis.insa-lyon.fr
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000519034800001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4321
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Author Valdes-Cortez, C.; Niatsetski, Y.; Perez-Calatayud, J.; Ballester, F.; Vijande, J.
Title A Monte Carlo study of the relative biological effectiveness in surface brachytherapy Type Journal Article
Year 2022 Publication Medical Physics Abbreviated Journal Med. Phys.
Volume 49 Issue Pages 5576-5588
Keywords (down) Monte Carlo; relative biological effectiveness; surface HDR brachytherapy
Abstract Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value.
Address [Valdes-Cortez, Christian] Hosp Reg Antofagasta, Nucl Med Dept, Antofagasta, Chile, Email: cvalcort@gmail.com
Corporate Author Thesis
Publisher Wiley Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes WOS:000811709400001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5262
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Author Oliver, S.; Gimenez-Alventosa, V.; Berumen, F.; Gimenez, V.; Beaulieu, L.; Ballester, F.; Vijande, J.
Title Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy Type Journal Article
Year 2023 Publication Zeitschrift für Medizinische Physik Abbreviated Journal Z. Med. Phys.
Volume 33 Issue 4 Pages 511-528
Keywords (down) Monte Carlo; PenRed; Brachytherapy; DICOM; Medical physics
Abstract Purpose: The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Methods and materials: Six benchmarking scenarios are explored to validate the use of PenRed and its improved bachytherapy-oriented capabilities for HDR brachytherapy. A new tally allowing the evaluation of collisional kerma for any material using the track length kerma estimator and the possibility to obtain the seed positions, weights and directions processing directly the DICOM file are now implemented in the PenRed distribution. The four non-clinical test cases developed by the Joint AAPM-ESTRO-ABG-ABS WG-DCAB were evaluated by comparing local and global absorbed dose differences with respect to established reference datasets. A prostate and a palliative lung cases, were also studied. For them, absorbed dose ratios, global absorbed dose differences, and cumulative dose-volume histograms were obtained and discussed. Results: The air-kerma strength and the dose rate constant corresponding to the two sources agree with the reference datatests within 0.3% (Sk) and 0.1% (K). With respect to the first three WG-DCAB test cases, more than 99.8% of the voxels present local (global) differences within +/- 1%(+/- 0.1%) of the reference datasets. For test Case 4 reference dataset, more than 94.9%(97.5%) of voxels show an agreement within +/- 1%(+/- 0.1%), better than similar benchmarking calculations in the literature. The track length kerma estimator scorer implemented increases the numerical efficiency of brachytherapy calculations two orders of magnitude, while the specific brachytherapy source allows the user to avoid the use of error-prone intermediate steps to translate the DICOM information into the simulation. In both clinical cases, only minor absorbed dose differences arise in the low-dose isodoses. 99.8% and 100% of the voxels have a global absorbed dose difference ratio within +/- 0.2%for the prostate and lung cases, respectively. The role played by the different segmentation and composition material in the bone structures was discussed, obtaining negligible absorbed dose differ-ences. Dose-volume histograms were in agreement with the reference data.Conclusions: PenRed incorporates new tallies and utilities and has been validated for its use for detailed and precise high-dose-rate brachytherapy simulations.
Address [Oliver, S.] Univ Politecn Valencia, Inst Segur Ind, Radiofis & Medioambiental ISIRYM, Camide Vera s n, Valencia 46022, Spain, Email: sanolgi@upvnet.upv.es
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0939-3889 ISBN Medium
Area Expedition Conference
Notes WOS:001137118400001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5885
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Author Fletcher, E.M.; Ballester, F.; Beaulieu, L.; Morrison, H.; Poher, A.; Rivard, M.J.; Sloboda, R.S.; Vijande, J.; Thomson, R.M.
Title Generation and comparison of 3D dosimetric reference datasets for COMS eye plaque brachytherapy using model-based dose calculations Type Journal Article
Year 2024 Publication Medical Physics Abbreviated Journal Med. Phys.
Volume 51 Issue Pages 694-706
Keywords (down) Monte Carlo; ocular brachytherapy; treatment planning
Abstract PurposeA joint Working Group of the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) was created to aid in the transition from the AAPM TG-43 dose calculation formalism, the current standard, to model-based dose calculations. This work establishes the first test cases for low-energy photon-emitting brachytherapy using model-based dose calculation algorithms (MBDCAs).Acquisition and Validation MethodsFive test cases are developed: (1) a single model 6711 125I brachytherapy seed in water, 13 seeds (2) individually and (3) in combination in water, (4) the full Collaborative Ocular Melanoma Study (COMS) 16-mm eye plaque in water, and (5) the full plaque in a realistic eye phantom. Calculations are done with four Monte Carlo (MC) codes and a research version of a commercial treatment planning system (TPS). For all test cases, local agreement of MC codes was within & SIM;2.5% and global agreement was & SIM;2% (4% for test case 5). MC agreement was within expected uncertainties. Local agreement of TPS with MC was within 5% for test case 1 and & SIM;20% for test cases 4 and 5, and global agreement was within 0.4% for test case 1 and 10% for test cases 4 and 5.Data Format and Usage NotesDose distributions for each set of MC and TPS calculations are available online () along with input files and all other information necessary to repeat the calculations.Potential ApplicationsThese data can be used to support commissioning of MBDCAs for low-energy brachytherapy as recommended by TGs 186 and 221 and AAPM Report 372. This work additionally lays out a sample framework for the development of test cases that can be extended to other applications beyond eye plaque brachytherapy.
Address [Fletcher, Elizabeth M.; Thomson, Rowan M.] Carleton Univ, Phys Dept, Carleton Lab Radiotherapy Phys, Ottawa, ON, Canada, Email: rthomson@physics.carleton.ca
Corporate Author Thesis
Publisher Wiley Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes WOS:001058112300001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5632
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Author Valdes-Cortez, C.; Mansour, I.; Rivard, M.J.; Ballester, F.; Mainegra-Hing, E.; Thomson, R.M.; Vijande, J.
Title A study of Type B uncertainties associated with the photoelectric effect in low-energy Monte Carlo simulations Type Journal Article
Year 2021 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 66 Issue 10 Pages 105014 - 14pp
Keywords (down) Monte Carlo simulations; brachytherapy; low energy physics; photoelectric effect
Abstract Purpose. To estimate Type B uncertainties in absorbed-dose calculations arising from the different implementations in current state-of-the-art Monte Carlo (MC) codes of low-energy photon cross-sections (<200 keV). Methods. MC simulations are carried out using three codes widely used in the low-energy domain: PENELOPE-2018, EGSnrc, and MCNP. Three dosimetry-relevant quantities are considered: mass energy-absorption coefficients for water, air, graphite, and their respective ratios; absorbed dose; and photon-fluence spectra. The absorbed dose and the photon-fluence spectra are scored in a spherical water phantom of 15 cm radius. Benchmark simulations using similar cross-sections have been performed. The differences observed between these quantities when different cross-sections are considered are taken to be a good estimator for the corresponding Type B uncertainties. Results. A conservative Type B uncertainty for the absorbed dose (k = 2) of 1.2%-1.7% (<50 keV), 0.6%-1.2% (50-100 keV), and 0.3% (100-200 keV) is estimated. The photon-fluence spectrum does not present clinically relevant differences that merit considering additional Type B uncertainties except for energies below 25 keV, where a Type B uncertainty of 0.5% is obtained. Below 30 keV, mass energy-absorption coefficients show Type B uncertainties (k = 2) of about 1.5% (water and air), and 2% (graphite), diminishing in all materials for larger energies and reaching values about 1% (40-50 keV) and 0.5% (50-75 keV). With respect to their ratios, the only significant Type B uncertainties are observed in the case of the water-to-graphite ratio for energies below 30 keV, being about 0.7% (k = 2). Conclusions. In contrast with the intermediate (about 500 keV) or high (about 1 MeV) energy domains, Type B uncertainties due to the different cross-sections implementation cannot be considered subdominant with respect to Type A uncertainties or even to other sources of Type B uncertainties (tally volume averaging, manufacturing tolerances, etc). Therefore, the values reported here should be accommodated within the uncertainty budget in low-energy photon dosimetry studies.
Address [Valdes-Cortez, Christian; Ballester, Facundo; Vijande, Javier] Univ Valencia UV, Dept Fis Atom Mol & Nucl, Burjassot, Spain, Email: javier.vijande@uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000655291500001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4847
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Author Etxebeste, A.; Barrio, J.; Muñoz, E.; Oliver, J.F.; Solaz, C.; Llosa, G.
Title 3D position determination in monolithic crystals coupled to SiPMs for PET Type Journal Article
Year 2016 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 61 Issue 10 Pages 3914-3934
Keywords (down) monolithic crystal; silicon photomultiplier; depth of interaction
Abstract The interest in using continuous monolithic crystals in positron emission tomography (PET) has grown in the last years. Coupled to silicon photomultipliers (SiPMs), the detector can combine high sensitivity and high resolution, the two main factors to be maximized in a positron emission tomograph. In this work, the position determination capability of a detector comprised of a 12 x 12 x 10 mm(3) LYSO crystal coupled to an 8 x 8-pixel array of SiPMs is evaluated. The 3D interaction position of.-rays is estimated using an analytical model of the light distribution including reflections on the facets of the crystal. Monte Carlo simulations have been performed to evaluate different crystal reflectors and geometries. The method has been characterized and applied to different cases. Intrinsic resolution obtained with the position estimation method used in this work, applied to experimental data, achieves sub-millimetre resolution values. Average resolution over the detector surface for 5 mm thick crystal is similar to 0.9 mm FWHM and similar to 1.2 mm FWHM for 10 mm thick crystal. Depth of interaction resolution is close to 2 mm FWHM in both cases, while the FWTM is similar to 5.3 mm for 5 mm thick crystal and similar to 9.6 mm for 10 mm thick crystal.
Address [Etxebeste, Ane; Barrio, John; Munoz, Enrique; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: ane.etxebeste@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000376792800014 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 2708
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Author Azevedo, C.D.R.; Baeza, A.; Chauveau, E.; Corbacho, J.A.; Diaz, J.; Domange, J.; Marquet, C.; Martinez-Roig, M.; Piquemal, F.; Roldan, C.; Vasco, J.; Veloso, J.F.C.A.; Yahlali, N.
Title Design, setup and routine operation of a water treatment system for the monitoring of low activities of tritium in water Type Journal Article
Year 2023 Publication Nuclear Engineering and Technology Abbreviated Journal Nucl. Eng. Technol.
Volume 55 Issue 7 Pages 2349-2355
Keywords (down) Monitoring radioactive discharges; Remote management; Tritium; Small size water treatment plant
Abstract In the TRITIUM project, an on-site monitoring system is being developed to measure tritium (3H) levels in water near nuclear power plants. The quite low-energy betas emitted by 3H have a very short average path in water (5 mm as shown by simulations for 18 keV electrons). This path would be further reduced by impurities present in the water, resulting in a significant reduction of the detection efficiency. Therefore, one of the essential requirements of the project is the elimination of these impurities through a filtration process and the removal of salts in solution. This paper describes a water treatment system developed for the project that meets the following requirements: the water produced should be of nearpure water quality according to ISO 3696 grade 3 standard (conductivity < 10 mS/cm); the system should operate autonomously and be remotely monitored.
Address [Azevedo, C. D. R.; Veloso, J. F. C. A.] Univ Aveiro, Dept Fis I3N, Aveiro, Portugal, Email: corbamer@unex.es
Corporate Author Thesis
Publisher Korean Nuclear Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1738-5733 ISBN Medium
Area Expedition Conference
Notes WOS:001015455100001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5569
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Author ATLAS Collaboration (Aad, G. et al); Aparisi Pozo, J.A.; Bailey, A.J.; Cabrera Urban, S.; Cardillo, F.; Castillo Gimenez, V.; Costa, M.J.; Escobar, C.; Estrada Pastor, O.; Ferrer, A.; Fiorini, L.; Fullana Torregrosa, E.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Gonzalvo Rodriguez, G.R.; Guerrero Rojas, J.G.R.; Higon-Rodriguez, E.; Lacasta, C.; Lozano Bahilo, J.J.; Mamuzic, J.; Marti-Garcia, S.; Martinez Agullo, P.; Mitsou, V.A.; Moreno Llacer, M.; Navarro-Gonzalez, J.; Poveda, J.; Prades Ibañez, A.; Ruiz-Martinez, A.; Sabatini, P.; Salt, J.; Sayago Galvan, I.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valls Ferrer, J.A.; Villaplana Perez, M.; Vos, M.
Title The ATLAS Fast TracKer system Type Journal Article
Year 2021 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 16 Issue 7 Pages P07006 - 61pp
Keywords (down) Modular electronics; Online farms and online filtering; Pattern recognition, cluster finding, calibration and fitting methods; Trigger concepts and systems (hardware and software)
Abstract The ATLAS Fast TracKer (FTK) was designed to provide full tracking for the ATLAS high-level trigger by using pattern recognition based on Associative Memory (AM) chips and fitting in high-speed field programmable gate arrays. The tracks found by the FTK are based on inputs from all modules of the pixel and silicon microstrip trackers. The as-built FTK system and components are described, as is the online software used to control them while running in the ATLAS data acquisition system. Also described is the simulation of the FTK hardware and the optimization of the AM pattern banks. An optimization for long-lived particles with large impact parameter values is included. A test of the FTK system with the data playback facility that allowed the FTK to be commissioned during the shutdown between Run 2 and Run 3 of the LHC is reported. The resulting tracks from part of the FTK system covering a limited eta-phi region of the detector are compared with the output from the FTK simulation. It is shown that FTK performance is in good agreement with the simulation.
Address [Duvnjak, D.; Jackson, P.; Kong, A. X. Y.; Oliver, J. L.; Ruggeri, T. A.; Sharma, A. S.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000791152800006 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5225
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Author Guerrero, M.; Olmo, G.J.; Rubiera-Garcia, D.
Title Double shadows of reflection-asymmetric wormholes supported by positive energy thin-shells Type Journal Article
Year 2021 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 04 Issue 4 Pages 066 - 26pp
Keywords (down) modified gravity; Wormholes; gravity
Abstract We consider reflection-asymmetric thin-shell wormholes within Palatini f(R) gravity using a matching procedure of two patches of electrovacuum space-times at a hypersurface (the shell) via suitable junction conditions. The conditions for having (linearly) stable wormholes supported by positive-energy matter sources are determined. We also identify some subsets of parameters able to locate the shell radius above the event horizon (when present) but below the photon sphere (on both sides). We illustrate with an specific example that such two photon spheres allow an observer on one of the sides of the wormhole to see another (circular) shadow in addition to the one generated by its own photon sphere, which is due to the photons passing above the maximum of the effective potential on its side and bouncing back across the throat due to a higher effective potential on the other side. We finally comment on the capability of these double shadows to seek for traces of new gravitational physics beyond that described by General Relativity.
Address [Guerrero, Merce; Rubiera-Garcia, Diego] Univ Complutense Madrid, Dept Fis Teor, E-28040 Madrid, Spain, Email: merguerr@ucm.es;
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:000644501000029 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4823
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Author Maso-Ferrando, A.; Sanchis-Gual, N.; Font, J.A.; Olmo, G.J.
Title Birth of baby universes from gravitational collapse in a modified-gravity scenario Type Journal Article
Year 2023 Publication Journal of Cosmology and Astroparticle Physics Abbreviated Journal J. Cosmol. Astropart. Phys.
Volume 06 Issue 6 Pages 028 - 19pp
Keywords (down) modified gravity; Wormholes
Abstract We consider equilibrium models of spherical boson stars in Palatini f (R) = R + CR2 gravity and study their collapse when perturbed. The Einstein-Klein-Gordon system is solved using a recently established correspondence in an Einstein frame representation. We find that, in that frame, the endpoint is a nonrotating black hole surrounded by a quasi -stationary cloud of scalar field. However, the dynamics in the f (R) frame is dramatically different. The innermost region of the collapsing object exhibits the formation of a finite -size, exponentially-expanding baby universe connected with the outer (parent) universe via a minimal area surface (a throat or umbilical cord). Our simulations indicate that this surface is at all times hidden inside a horizon, causally disconnecting the baby universe from observers above the horizon. The implications of our findings in other areas of gravitational physics are also discussed.
Address [Maso-Ferrando, Andreu; Olmo, Gonzalo J.] Univ Valencia, Ctr Mixto, CSIC, Dept Fis Teor, Valencia 46100, Spain, Email: andreu.maso@uv.es;
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1475-7516 ISBN Medium
Area Expedition Conference
Notes WOS:001025474200010 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5577
Permanent link to this record