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Author Coppola, M.; Gomez Dumm, D.; Noguera, S.; Scoccola, N.N.
Title Magnetic field driven enhancement of the weak decay width of charged pions Type Journal Article
Year 2020 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 09 Issue 9 Pages 058 - 19pp
Keywords (down) QCD Phenomenology
Abstract We study the effect of a uniform magnetic field B on the decays pi- > l- nu_l bar, where l(-)=e(-), μ(-), carrying out a general analysis that includes four pi (-) decay constants. Taking the values of these constants from a chiral effective Nambu-Jona-Lasinio (NJL) model, it is seen that the total decay rate gets strongly increased with respect to the B = 0 case, with an enhancement factor ranging from similar to 10 for eB = 0.1 GeV2 up to similar to 10(3) for eB = 1 GeV2. The ratio between electronic and muonic decays gets also enhanced, reaching a value of about 1 : 2 for eB = 1 GeV2. In addition, we find that for large B the angular distribution of outgoing antineutrinos shows a significant suppression in the direction of the magnetic field.
Address [Coppola, Maximo; Scoccola, Norberto N.] Consejo Nacl Invest Cient & Tecn, Rivadavia 1917, RA-1033 Buenos Aires, DF, Argentina, Email: coppola@tandar.cnea.gov.ar;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:000570908100001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4534
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Author PTOLEMY Collaboration (Betti, M.G. et al); de Salas, P.F.; Gariazzo, S.; Pastor, S.
Title A design for an electromagnetic filter for precision energy measurements at the tritium endpoint Type Journal Article
Year 2019 Publication Progress in Particle and Nuclear Physics Abbreviated Journal Prog. Part. Nucl. Phys.
Volume 106 Issue Pages 120-131
Keywords (down) PTOLEMY; Relic neutrino; Cosmic Neutrino Background; CNB; Neutrino mass; Transverse drift filter
Abstract We present a detailed description of the electromagnetic filter for the PTOLEMY project to directly detect the Cosmic Neutrino Background (CNB). Starting with an initial estimate for the orbital magnetic moment, the higher-order drift process of E x B is configured to balance the gradient-B drift motion of the electron in such a way as to guide the trajectory into the standing voltage potential along the mid-plane of the filter. As a function of drift distance along the length of the filter, the filter zooms in with exponentially increasing precision on the transverse velocity component of the electron kinetic energy. This yields a linear dimension for the total filter length that is exceptionally compact compared to previous techniques for electromagnetic filtering. The parallel velocity component of the electron kinetic energy oscillates in an electrostatic harmonic trap as the electron drifts along the length of the filter. An analysis of the phase-space volume conservation validates the expected behavior of the filter from the adiabatic invariance of the orbital magnetic moment and energy conservation following Liouville's theorem for Hamiltonian systems. (C) 2019 Elsevier B.V. All rights reserved.
Address [Hochberg, Y.] Hebrew Univ Jerusalem, Racah Inst Phys, Jerusalem, Israel, Email: cgtully@Princeton.EDU
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0146-6410 ISBN Medium
Area Expedition Conference
Notes WOS:000464490900003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3978
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Author Brzezinski, K. et al
Title Detection of range shifts in proton beam therapy using the J-PET scanner: a patient simulation study Type Journal Article
Year 2023 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 68 Issue 14 Pages 145016 - 17pp
Keywords (down) proton therapy; positron emission tomography; in vivo range verification; J-PET; Monte Carlo
Abstract Objective. The Jagiellonian positron emission tomography (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasibility of using J-PET for range monitoring by means of a detailed Monte Carlo simulation study of 95 patients who underwent proton therapy at the Cyclotron Centre Bronowice (CCB) in Krakow, Poland. Approach. Discrepancies between prescribed and delivered treatments were artificially introduced in the simulations by means of shifts in patient positioning and in the Hounsfield unit to the relative proton stopping power calibration curve. A dual-layer, cylindrical J-PET geometry was simulated in an in-room monitoring scenario and a triple-layer, dual-head geometry in an in-beam protocol. The distribution of range shifts in reconstructed PET activity was visualized in the beam's eye view. Linear prediction models were constructed from all patients in the cohort, using the mean shift in reconstructed PET activity as a predictor of the mean proton range deviation. Main results. Maps of deviations in the range of reconstructed PET distributions showed agreement with those of deviations in dose range in most patients. The linear prediction model showed a good fit, with coefficient of determination r (2) = 0.84 (in-room) and 0.75 (in-beam). Residual standard error was below 1 mm: 0.33 mm (in-room) and 0.23 mm (in-beam). Significance. The precision of the proposed prediction models shows the sensitivity of the proposed J-PET scanners to shifts in proton range for a wide range of clinical treatment plans. Furthermore, it motivates the use of such models as a tool for predicting proton range deviations and opens up new prospects for investigations into the use of intra-treatment PET images for predicting clinical metrics that aid in the assessment of the quality of delivered treatment.
Address [Brzezinski, Karol; Gajewski, Jan; Kopec, Renata; Olko, Pawel; Stasica, Paulina; Rucinski, Antoni] Polish Acad Sci, Inst Nucl Phys, Krakow, Poland, Email: karol.brzezinski@ific.uv.es
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:001026535700001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5616
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Author Borys, D. et al; Brzezinski, K.
Title ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging Type Journal Article
Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 67 Issue 22 Pages 224002 - 15pp
Keywords (down) proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging
Abstract Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022).
Address [Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000885248200001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 5416
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Author Di Gregorio, E.; Staelens, M.; Hosseinkhah, N.; Karimpoor, M.; Liburd, J.; Lim, L.; Shankar, K.; Tuszynski, J.A.
Title Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer's and Other Neurodegenerative Diseases Type Journal Article
Year 2024 Publication Nanomaterials Abbreviated Journal Nanomaterials
Volume 14 Issue 13 Pages 1093 - 21pp
Keywords (down) proteins; protein dynamics; protein structure; non-invasive therapies; low-level laser therapy; spectroscopy; amide bands; amide I; spectral decomposition
Abstract In small clinical studies, the application of transcranial photobiomodulation (PBM), which typically delivers low-intensity near-infrared (NIR) to treat the brain, has led to some remarkable results in the treatment of dementia and several neurodegenerative diseases. However, despite the extensive literature detailing the mechanisms of action underlying PBM outcomes, the specific mechanisms affecting neurodegenerative diseases are not entirely clear. While large clinical trials are warranted to validate these findings, evidence of the mechanisms can explain and thus provide credible support for PBM as a potential treatment for these diseases. Tubulin and its polymerized state of microtubules have been known to play important roles in the pathology of Alzheimer's and other neurodegenerative diseases. Thus, we investigated the effects of PBM on these cellular structures in the quest for insights into the underlying therapeutic mechanisms. In this study, we employed a Raman spectroscopic analysis of the amide I band of polymerized samples of tubulin exposed to pulsed low-intensity NIR radiation (810 nm, 10 Hz, 22.5 J/cm2 dose). Peaks in the Raman fingerprint region (300-1900 cm-1)-in particular, in the amide I band (1600-1700 cm-1)-were used to quantify the percentage of protein secondary structures. Under this band, hidden signals of C=O stretching, belonging to different structures, are superimposed, producing a complex signal as a result. An accurate decomposition of the amide I band is therefore required for the reliable analysis of the conformation of proteins, which we achieved through a straightforward method employing a Voigt profile. This approach was validated through secondary structure analyses of unexposed control samples, for which comparisons with other values available in the literature could be conducted. Subsequently, using this validated method, we present novel findings of statistically significant alterations in the secondary structures of polymerized NIR-exposed tubulin, characterized by a notable decrease in alpha-helix content and a concurrent increase in beta-sheets compared to the control samples. This PBM-induced alpha-helix to beta-sheet transition connects to reduced microtubule stability and the introduction of dynamism to allow for the remodeling and, consequently, refreshing of microtubule structures. This newly discovered mechanism could have implications for reducing the risks associated with brain aging, including neurodegenerative diseases like Alzheimer's disease, through the introduction of an intervention following this transition.
Address [Di Gregorio, Elisabetta; Staelens, Michael; Tuszynski, Jack A.] Univ Alberta, Fac Sci, Dept Phys, Edmonton, AB T6G 2E1, Canada, Email: michael.staelens@ific.uv.es
Corporate Author Thesis
Publisher Mdpi Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN ISBN Medium
Area Expedition Conference
Notes WOS:001269841000001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 6204
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Author Bruschini, R.; Gonzalez, P.
Title chi(c1)(2p): an overshadowed charmoniumlike resonance Type Journal Article
Year 2023 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 02 Issue 2 Pages 216 - 23pp
Keywords (down) Properties of Hadrons; Quarkonium
Abstract A thorough study of the J(PC )= 1(++) elastic D0 & macr;D*(0) and D+D*(-) scattering, where the form of the meson-meson interaction is inferred from lattice QCD calculations of string breaking, is carried out for center-of-mass energies up to 4 GeV. We show that the presence of chi c1(3872), which can be naturally assigned to either a bound or virtual charmoniumlike state close below the D0 & macr;D*0 threshold, can overshadow a quasiconventional charmoniumlike resonance lying above threshold. This makes difficult the experimental detection of this resonance through the D0 & macr;D*(0) and D+D*(-) channels, despite being its expected main decay modes. We analyze alternative strong and electromagnetic decay modes. Comparison with existing data shows that this resonance may have already been observed through its decay to omega J/psi.
Address [Bruschini, R.] Ohio State Univ, Dept Phys, 191 West Woodruff Ave, Columbus, OH 43210 USA, Email: bruschini.1@osu.edu;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:000938122900008 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5490
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Author Consiglio, R.; de Salas, P.F.; Mangano, G.; Miele, G.; Pastor, S.; Pisanti, O.
Title PArthENoPE reloaded Type Journal Article
Year 2018 Publication Computer Physics Communications Abbreviated Journal Comput. Phys. Commun.
Volume 233 Issue Pages 237-242
Keywords (down) Primordial nucleosynthesis; Cosmology; Neutrino physics
Abstract We describe the main features of a new and updated version of the program PArthENoPE, which computes the abundances of light elements produced during Big Bang Nucleosynthesis. As the previous first release in 2008, the new one, PArthENoPE2.0, is publicly available and distributed from the code site, http://parthenope.na.infn.it . Apart from minor changes, which will be also detailed, the main improvements are as follows. The powerful, but not freely accessible, NAG routines have been substituted by ODEPACK libraries, without any significant loss in precision. Moreover, we have developed a Graphical User Interface (GUI) which allows a friendly use of the code and a simpler implementation of running for grids of input parameters. New Version program summary Program Title: PArthENoPE2.0 Program Files doi : http://dx.doi.org/10.17632/wvgr7d8yt9.1 Licensing provisions: GPLv3 Programming language: Fortran 77 and Python Supplementary material: User Manual available on the web page http://parthenope.na.infn.it Journal reference of previous version: Comput. Phys. Commun. 178 (2008) 956 971 Does the new version supersede the previous version?: Yes Reasons for the new version: Make the code more versatile and user friendly Summary of revisions: (1) Publicly available libraries (2) GUI for configuration Nature of problem: Computation of yields of light elements synthesized in the primordial universe Solution method: Livermore Solver for Ordinary Differential Equations (LSODE) for stiff and nonstiff systems
Address [Consiglio, R.; Miele, G.; Pisanti, O.] Univ Napoli Federico II, Dipartimento Fis E Pancini, Via Cintia, I-80126 Naples, Italy, Email: pisanti@na.infn.it
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0010-4655 ISBN Medium
Area Expedition Conference
Notes WOS:000444667100020 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3729
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Author Gariazzo, S.; de Salas, P.F.; Pisanti, O.; Consiglio, R.
Title PArthENoPE revolutions Type Journal Article
Year 2022 Publication Computer Physics Communications Abbreviated Journal Comput. Phys. Commun.
Volume 271 Issue Pages 108205 - 13pp
Keywords (down) Primordial nucleosynthesis; Cosmology; Neutrino physics
Abstract This paper presents the main features of a new and updated version of the program PArthENoPE, which the community has been using for many years for computing the abundances of light elements produced during Big Bang Nucleosynthesis. This is the third release of the PArthENoPE code, after the 2008 and the 2018 ones, and will be distributed from the code's website, http://parthenope.na.infn.it. Apart from minor changes, the main improvements in this new version include a revisited implementation of the nuclear rates for the most important reactions of deuterium destruction, H-2(p,gamma) He-3, H-2(d, n)He-3 and H-2(d, p)H-3, and a re-designed GUI, which extends the functionality of the previous one. The new GUI, in particular, supersedes the previous tools for running over grids of parameters with a better management of parallel runs, and it offers a brand-new set of functions for plotting the results. Program summary Program title: PArthENoPE 3.0 CPC Library link to program files: https://doi.org/10.17632/wygr7d8yt9.2 Developer's repository link: http://parthenope.na.infn.it Licensing provisions: GPLv3 Programming language: Fortran 77 and Python Nature of problem: Computation of yields of light elements synthesized in the primordial universe Solution method: Livermore Solver for Ordinary Differential Equations (LSODE) for stiff and nonstiff systems, Python GUI for running and plotting Journal reference of previous version: Comput. Phys. Commun. 233 (2018) 237-242 Does the new version supersede the previous version?: Yes Reasons for the new version: Update of the physics and improvements in the GUI Summary of revisions: Update of the physics implemented in the Fortran code and improvements in the GUI functionalities, in particular new plotting functions.
Address [Gariazzo, S.] INFN, Sez Torino, Via P Giuria 1, I-10125 Turin, Italy, Email: pisanti@na.infn.it
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0010-4655 ISBN Medium
Area Expedition Conference
Notes WOS:000720461800020 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5027
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Author Villanueva-Domingo, P.; Mena, O.; Palomares-Ruiz, S.
Title A Brief Review on Primordial Black Holes as Dark Matter Type Journal Article
Year 2021 Publication Frontiers in Astronomy and Space Sciences Abbreviated Journal Front. Astron. Space Sci.
Volume 8 Issue Pages 681084 - 10pp
Keywords (down) primordial black holes; dark matter; cosmology; accretion; 21 cm cosmology; gravitational waves; cosmic microwave background; microlensing
Abstract Primordial black holes (PBHs) represent a natural candidate for one of the components of the dark matter (DM) in the Universe. In this review, we shall discuss the basics of their formation, abundance and signatures. Some of their characteristic signals are examined, such as the emission of particles due to Hawking evaporation and the accretion of the surrounding matter, effects which could leave an impact in the evolution of the Universe and the formation of structures. The most relevant probes capable of constraining their masses and population are discussed.
Address [Villanueva-Domingo, Pablo; Mena, Olga; Palomares-Ruiz, Sergio] CSIC Univ Valencia, Inst Fis Corpuscular IFIC, Paterna, Spain, Email: pablo.villanueva.domingo@gmail.com
Corporate Author Thesis
Publisher Frontiers Media Sa Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 2296-987x ISBN Medium
Area Expedition Conference
Notes WOS:000660081700001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4852
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Author Han, C.; Lopez-Ibañez, M.L.; Melis, A.; Vives, O.; Wu, L.; Yang, J.M.
Title LFV and (g-2) in non-universal SUSY models with light higgsinos Type Journal Article
Year 2020 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 05 Issue 5 Pages 102 - 32pp
Keywords (down) Precision QED; Supersymmetric Standard Model; GUT; Neutrino Physics
Abstract We consider a supersymmetric type-I seesaw framework with non-universal scalar masses at the GUT scale to explain the long-standing discrepancy of the anomalous magnetic moment of the muon. We find that it is difficult to accommodate the muon g-2 while keeping charged-lepton flavor violating processes under control for the conventional SO(10)-based relation between the up sector and neutrino sector. However, such tension can be relaxed by adding a Georgi-Jarlskog factor for the Yukawa matrices, which requires a non-trivial GUT-based model. In this model, we find that both observables are compatible for small mixings, CKM-like, in the neutrino Dirac Yukawa matrix.
Address [Han, C.] KIAS, Sch Phys, 85 Hoegiro, Seoul 02455, South Korea, Email: hancheng@itp.ac.cn;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:000537114700003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4421
Permanent link to this record