Renner, J., Cervera-Villanueva, A., Hernando, J. A., Izmaylov, A., Monrabal, F., Muñoz, J., et al. (2015). Improved background rejection in neutrinoless double beta decay experiments using a magnetic field in a high pressure xenon TPC. J. Instrum., 10, P12020–19pp.
Abstract: We demonstrate that the application of an external magnetic field could lead to an improved background rejection in neutrinoless double-beta (0 nu beta beta) decay experiments using a high-pressure xenon (HPXe) TPC. HPXe chambers are capable of imaging electron tracks, a feature that enhances the separation between signal events (the two electrons emitted in the 0 nu beta beta decay of Xe-136) and background events, arising chiefly from single electrons of kinetic energy compatible with the end-point of the 0 nu beta beta decay (Q(beta beta)). Applying an external magnetic field of sufficiently high intensity (in the range of 0.5-1 Tesla for operating pressures in the range of 5-15 atmospheres) causes the electrons to produce helical tracks. Assuming the tracks can be properly reconstructed, the sign of the curvature can be determined at several points along these tracks, and such information can be used to separate signal (0 nu beta beta) events containing two electrons producing a track with two different directions of curvature from background (single-electron) events producing a track that should spiral in a single direction. Due to electron multiple scattering, this strategy is not perfectly efficient on an event-by-event basis, but a statistical estimator can be constructed which can be used to reject background events by one order of magnitude at a moderate cost (about 30%) in signal efficiency. Combining this estimator with the excellent energy resolution and topological signature identification characteristic of the HPXe TPC, it is possible to reach a background rate of less than one count per ton-year of exposure. Such a low background rate is an essential feature of the next generation of 0 nu beta beta experiments, aiming to fully explore the inverse hierarchy of neutrino masses.
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NEXT Collaboration(Alvarez, V. et al), Carcel, S., Cervera-Villanueva, A., Diaz, J., Ferrario, P., Gil, A., et al. (2013). Operation and first results of the NEXT-DEMO prototype using a silicon photomultiplier tracking array. J. Instrum., 8, P09011–20pp.
Abstract: NEXT-DEMO is a high-pressure xenon gas TPC which acts as a technological test-bed and demonstrator for the NEXT-100 neutrinoless double beta decay experiment. In its current configuration the apparatus fully implements the NEXT-100 design concept. This is an asymmetric TPC, with an energy plane made of photomultipliers and a tracking plane made of silicon photomultipliers (SiPM) coated with TPB. The detector in this new configuration has been used to reconstruct the characteristic signature of electrons in dense gas, demonstrating the ability to identify the MIP and “blob” regions. Moreover, the SiPM tracking plane allows for the definition of a large fiducial region in which an excellent energy resolution of 1.82% FWHM at 511 keV has been measured (a value which extrapolates to 0.83% at the xenon Q(beta beta)).
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Carrasco-Ribelles, L. A., Pardo-Mas, J. R., Tortajada, S., Saez, C., Valdivieso, B., & Garcia-Gomez, J. M. (2021). Predicting morbidity by local similarities in multi-scale patient trajectories. J. Biomed. Inform., 120, 103837–9pp.
Abstract: Patient Trajectories (PTs) are a method of representing the temporal evolution of patients. They can include information from different sources and be used in socio-medical or clinical domains. PTs have generally been used to generate and study the most common trajectories in, for instance, the development of a disease. On the other hand, healthcare predictive models generally rely on static snapshots of patient information. Only a few works about prediction in healthcare have been found that use PTs, and therefore benefit from their temporal dimension. All of them, however, have used PTs created from single-source information. Therefore, the use of longitudinal multi-scale data to build PTs and use them to obtain predictions about health conditions is yet to be explored. Our hypothesis is that local similarities on small chunks of PTs can identify similar patients concerning their future morbidities. The objectives of this work are (1) to develop a methodology to identify local similarities between PTs before the occurrence of morbidities to predict these on new query individuals; and (2) to validate this methodology on risk prediction of cardiovascular diseases (CVD) occurrence in patients with diabetes. We have proposed a novel formal definition of PTs based on sequences of longitudinal multi-scale data. Moreover, a dynamic programming methodology to identify local alignments on PTs for predicting future morbidities is proposed. Both the proposed methodology for PT definition and the alignment algorithm are generic to be applied on any clinical domain. We validated this solution for predicting CVD in patients with diabetes and we achieved a precision of 0.33, a recall of 0.72 and a specificity of 0.38. Therefore, the proposed solution in the diabetes use case can result of utmost utility to secondary screening.
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Ruhr, F. et al, Escobar, C., & Miñano, M. (2020). Testbeam studies of barrel and end-cap modules for the ATLAS ITk strip detector before and after irradiation. Nucl. Instrum. Methods Phys. Res. A, 979, 164430–6pp.
Abstract: In order to cope with the occupancy and radiation doses expected at the High-Luminosity LHC, the ATLAS experiment will replace its Inner Detector with an all-silicon Inner Tracker (ITk), consisting of pixel and strip subsystems. In the last two years, several prototype ITk strip modules have been tested using beams of high energy electrons produced at the DESY-II testbeam facility. Tracking was provided by EUDET telescopes. The modules tested are built from two sensor types: the rectangular ATLAS17LS, which will be used in the outer layers of the central barrel region of the detector, and the annular ATLAS12EC, which will be used in the innermost ring (R0) of the forward region. Additionally, a structure with two RO modules positioned back-to-back has been measured, demonstrating space point reconstruction using the stereo angle of the strips. Finally, one barrel and one RO module have been measured after irradiation to 40% beyond the expected end-of-lifetime fluence. The data obtained allow for thorough tests of the module performance, including charge collection, noise occupancy, detection efficiency, and tracking performance. The results give confidence that the ITk strip detector will meet the requirements of the ATLAS experiment.
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Zhao, X., McLain, M. A., Vijande, J., Ferrando, A., Carr, L. D., & Garcia-March, M. A. (2019). Nonequilibrium quantum dynamics of partial symmetry breaking for ultracold bosons in an optical lattice ring trap. New J. Phys., 21, 043042–13pp.
Abstract: A vortex in a Bose-Einstein condensate on a ring undergoes quantum dynamics in response to a quantum quench in terms of partial symmetry breaking from a uniform lattice to a biperiodic one. Neither the current, a macroscopic measure, nor fidelity, a microscopic measure, exhibit critical behavior. Instead, the symmetry memory succeeds in identifying the critical symmetry breaking at which the system begins to forget its initial symmetry state. We further identify a symmetry energy difference in the low lying excited states which trends with the symmetry memory.
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