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Author |
Oliver, S.; Gimenez-Alventosa, V.; Berumen, F.; Gimenez, V.; Beaulieu, L.; Ballester, F.; Vijande, J. |
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Title |
Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy |
Type |
Journal Article |
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Year |
2023 |
Publication |
Zeitschrift für Medizinische Physik |
Abbreviated Journal |
Z. Med. Phys. |
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Volume |
33 |
Issue |
4 |
Pages |
511-528 |
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Keywords  |
Monte Carlo; PenRed; Brachytherapy; DICOM; Medical physics |
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Abstract |
Purpose: The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Methods and materials: Six benchmarking scenarios are explored to validate the use of PenRed and its improved bachytherapy-oriented capabilities for HDR brachytherapy. A new tally allowing the evaluation of collisional kerma for any material using the track length kerma estimator and the possibility to obtain the seed positions, weights and directions processing directly the DICOM file are now implemented in the PenRed distribution. The four non-clinical test cases developed by the Joint AAPM-ESTRO-ABG-ABS WG-DCAB were evaluated by comparing local and global absorbed dose differences with respect to established reference datasets. A prostate and a palliative lung cases, were also studied. For them, absorbed dose ratios, global absorbed dose differences, and cumulative dose-volume histograms were obtained and discussed. Results: The air-kerma strength and the dose rate constant corresponding to the two sources agree with the reference datatests within 0.3% (Sk) and 0.1% (K). With respect to the first three WG-DCAB test cases, more than 99.8% of the voxels present local (global) differences within +/- 1%(+/- 0.1%) of the reference datasets. For test Case 4 reference dataset, more than 94.9%(97.5%) of voxels show an agreement within +/- 1%(+/- 0.1%), better than similar benchmarking calculations in the literature. The track length kerma estimator scorer implemented increases the numerical efficiency of brachytherapy calculations two orders of magnitude, while the specific brachytherapy source allows the user to avoid the use of error-prone intermediate steps to translate the DICOM information into the simulation. In both clinical cases, only minor absorbed dose differences arise in the low-dose isodoses. 99.8% and 100% of the voxels have a global absorbed dose difference ratio within +/- 0.2%for the prostate and lung cases, respectively. The role played by the different segmentation and composition material in the bone structures was discussed, obtaining negligible absorbed dose differ-ences. Dose-volume histograms were in agreement with the reference data.Conclusions: PenRed incorporates new tallies and utilities and has been validated for its use for detailed and precise high-dose-rate brachytherapy simulations. |
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Address |
[Oliver, S.] Univ Politecn Valencia, Inst Segur Ind, Radiofis & Medioambiental ISIRYM, Camide Vera s n, Valencia 46022, Spain, Email: sanolgi@upvnet.upv.es |
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Elsevier |
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English |
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ISSN |
0939-3889 |
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Conference |
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Notes |
WOS:001137118400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5885 |
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Author |
Fletcher, E.M.; Ballester, F.; Beaulieu, L.; Morrison, H.; Poher, A.; Rivard, M.J.; Sloboda, R.S.; Vijande, J.; Thomson, R.M. |
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Title |
Generation and comparison of 3D dosimetric reference datasets for COMS eye plaque brachytherapy using model-based dose calculations |
Type |
Journal Article |
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Year |
2024 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
51 |
Issue |
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Pages |
694-706 |
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Keywords |
Monte Carlo; ocular brachytherapy; treatment planning |
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Abstract |
PurposeA joint Working Group of the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) was created to aid in the transition from the AAPM TG-43 dose calculation formalism, the current standard, to model-based dose calculations. This work establishes the first test cases for low-energy photon-emitting brachytherapy using model-based dose calculation algorithms (MBDCAs).Acquisition and Validation MethodsFive test cases are developed: (1) a single model 6711 125I brachytherapy seed in water, 13 seeds (2) individually and (3) in combination in water, (4) the full Collaborative Ocular Melanoma Study (COMS) 16-mm eye plaque in water, and (5) the full plaque in a realistic eye phantom. Calculations are done with four Monte Carlo (MC) codes and a research version of a commercial treatment planning system (TPS). For all test cases, local agreement of MC codes was within & SIM;2.5% and global agreement was & SIM;2% (4% for test case 5). MC agreement was within expected uncertainties. Local agreement of TPS with MC was within 5% for test case 1 and & SIM;20% for test cases 4 and 5, and global agreement was within 0.4% for test case 1 and 10% for test cases 4 and 5.Data Format and Usage NotesDose distributions for each set of MC and TPS calculations are available online () along with input files and all other information necessary to repeat the calculations.Potential ApplicationsThese data can be used to support commissioning of MBDCAs for low-energy brachytherapy as recommended by TGs 186 and 221 and AAPM Report 372. This work additionally lays out a sample framework for the development of test cases that can be extended to other applications beyond eye plaque brachytherapy. |
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Address |
[Fletcher, Elizabeth M.; Thomson, Rowan M.] Carleton Univ, Phys Dept, Carleton Lab Radiotherapy Phys, Ottawa, ON, Canada, Email: rthomson@physics.carleton.ca |
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Publisher |
Wiley |
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English |
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Series Issue |
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Edition |
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ISSN |
0094-2405 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001058112300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5632 |
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Author |
Valdes-Cortez, C.; Mansour, I.; Rivard, M.J.; Ballester, F.; Mainegra-Hing, E.; Thomson, R.M.; Vijande, J. |
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Title |
A study of Type B uncertainties associated with the photoelectric effect in low-energy Monte Carlo simulations |
Type |
Journal Article |
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Year |
2021 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
66 |
Issue |
10 |
Pages |
105014 - 14pp |
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Keywords |
Monte Carlo simulations; brachytherapy; low energy physics; photoelectric effect |
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Abstract |
Purpose. To estimate Type B uncertainties in absorbed-dose calculations arising from the different implementations in current state-of-the-art Monte Carlo (MC) codes of low-energy photon cross-sections (<200 keV). Methods. MC simulations are carried out using three codes widely used in the low-energy domain: PENELOPE-2018, EGSnrc, and MCNP. Three dosimetry-relevant quantities are considered: mass energy-absorption coefficients for water, air, graphite, and their respective ratios; absorbed dose; and photon-fluence spectra. The absorbed dose and the photon-fluence spectra are scored in a spherical water phantom of 15 cm radius. Benchmark simulations using similar cross-sections have been performed. The differences observed between these quantities when different cross-sections are considered are taken to be a good estimator for the corresponding Type B uncertainties. Results. A conservative Type B uncertainty for the absorbed dose (k = 2) of 1.2%-1.7% (<50 keV), 0.6%-1.2% (50-100 keV), and 0.3% (100-200 keV) is estimated. The photon-fluence spectrum does not present clinically relevant differences that merit considering additional Type B uncertainties except for energies below 25 keV, where a Type B uncertainty of 0.5% is obtained. Below 30 keV, mass energy-absorption coefficients show Type B uncertainties (k = 2) of about 1.5% (water and air), and 2% (graphite), diminishing in all materials for larger energies and reaching values about 1% (40-50 keV) and 0.5% (50-75 keV). With respect to their ratios, the only significant Type B uncertainties are observed in the case of the water-to-graphite ratio for energies below 30 keV, being about 0.7% (k = 2). Conclusions. In contrast with the intermediate (about 500 keV) or high (about 1 MeV) energy domains, Type B uncertainties due to the different cross-sections implementation cannot be considered subdominant with respect to Type A uncertainties or even to other sources of Type B uncertainties (tally volume averaging, manufacturing tolerances, etc). Therefore, the values reported here should be accommodated within the uncertainty budget in low-energy photon dosimetry studies. |
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Address |
[Valdes-Cortez, Christian; Ballester, Facundo; Vijande, Javier] Univ Valencia UV, Dept Fis Atom Mol & Nucl, Burjassot, Spain, Email: javier.vijande@uv.es |
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Publisher |
Iop Publishing Ltd |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9155 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000655291500001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4847 |
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Author |
Etxebeste, A.; Barrio, J.; Muñoz, E.; Oliver, J.F.; Solaz, C.; Llosa, G. |
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Title |
3D position determination in monolithic crystals coupled to SiPMs for PET |
Type |
Journal Article |
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Year |
2016 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
61 |
Issue |
10 |
Pages |
3914-3934 |
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Keywords |
monolithic crystal; silicon photomultiplier; depth of interaction |
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Abstract |
The interest in using continuous monolithic crystals in positron emission tomography (PET) has grown in the last years. Coupled to silicon photomultipliers (SiPMs), the detector can combine high sensitivity and high resolution, the two main factors to be maximized in a positron emission tomograph. In this work, the position determination capability of a detector comprised of a 12 x 12 x 10 mm(3) LYSO crystal coupled to an 8 x 8-pixel array of SiPMs is evaluated. The 3D interaction position of.-rays is estimated using an analytical model of the light distribution including reflections on the facets of the crystal. Monte Carlo simulations have been performed to evaluate different crystal reflectors and geometries. The method has been characterized and applied to different cases. Intrinsic resolution obtained with the position estimation method used in this work, applied to experimental data, achieves sub-millimetre resolution values. Average resolution over the detector surface for 5 mm thick crystal is similar to 0.9 mm FWHM and similar to 1.2 mm FWHM for 10 mm thick crystal. Depth of interaction resolution is close to 2 mm FWHM in both cases, while the FWTM is similar to 5.3 mm for 5 mm thick crystal and similar to 9.6 mm for 10 mm thick crystal. |
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Address |
[Etxebeste, Ane; Barrio, John; Munoz, Enrique; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: ane.etxebeste@ific.uv.es |
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Iop Publishing Ltd |
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English |
Summary Language |
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Series Issue |
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ISSN |
0031-9155 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000376792800014 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2708 |
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Author |
Azevedo, C.D.R.; Baeza, A.; Chauveau, E.; Corbacho, J.A.; Diaz, J.; Domange, J.; Marquet, C.; Martinez-Roig, M.; Piquemal, F.; Roldan, C.; Vasco, J.; Veloso, J.F.C.A.; Yahlali, N. |
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Title |
Design, setup and routine operation of a water treatment system for the monitoring of low activities of tritium in water |
Type |
Journal Article |
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Year |
2023 |
Publication |
Nuclear Engineering and Technology |
Abbreviated Journal |
Nucl. Eng. Technol. |
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Volume |
55 |
Issue |
7 |
Pages |
2349-2355 |
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Keywords |
Monitoring radioactive discharges; Remote management; Tritium; Small size water treatment plant |
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Abstract |
In the TRITIUM project, an on-site monitoring system is being developed to measure tritium (3H) levels in water near nuclear power plants. The quite low-energy betas emitted by 3H have a very short average path in water (5 mm as shown by simulations for 18 keV electrons). This path would be further reduced by impurities present in the water, resulting in a significant reduction of the detection efficiency. Therefore, one of the essential requirements of the project is the elimination of these impurities through a filtration process and the removal of salts in solution. This paper describes a water treatment system developed for the project that meets the following requirements: the water produced should be of nearpure water quality according to ISO 3696 grade 3 standard (conductivity < 10 mS/cm); the system should operate autonomously and be remotely monitored. |
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Address |
[Azevedo, C. D. R.; Veloso, J. F. C. A.] Univ Aveiro, Dept Fis I3N, Aveiro, Portugal, Email: corbamer@unex.es |
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Korean Nuclear Soc |
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English |
Summary Language |
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Edition |
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ISSN |
1738-5733 |
ISBN |
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Conference |
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Notes |
WOS:001015455100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5569 |
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Author |
MoEDAL Collaboration (Acharya, B. et al); Bernabeu, J.; Garcia, C.; King, M.; Mitsou, V.A.; Vento, V.; Vives, O. |
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Title |
The physics programme of the MoEDAL experiment at the LHC |
Type |
Journal Article |
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Year |
2014 |
Publication |
International Journal of Modern Physics A |
Abbreviated Journal |
Int. J. Mod. Phys. A |
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Volume |
29 |
Issue |
23 |
Pages |
1430050 - 91pp |
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Keywords |
MoEDAL; LHC magnetic monopole; monopolium; dyons; (pseudo-)stable massive charged particle; supersymmetry; technicolor; extra dimensions; dark matter; doubly charged particles; highly ionizing particles; physics beyond the Standard Model |
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Abstract |
The MoEDAL experiment at Point 8 of the LHC ring is the seventh and newest LHC experiment. It is dedicated to the search for highly-ionizing particle avatars of physics beyond the Standard Model, extending significantly the discovery horizon of the LHC. A MoEDAL discovery would have revolutionary implications for our fundamental understanding of the Microcosm. MoEDAL is an unconventional and largely passive LHC detector comprised of the largest array of Nuclear Track Detector stacks ever deployed at an accelerator, surrounding the intersection region at Point 8 on the LHC ring. Another novel feature is the use of paramagnetic trapping volumes to capture both electrically and magnetically charged highly-ionizing particles predicted in new physics scenarios. It includes an array of TimePix pixel devices for monitoring highly-ionizing particle backgrounds. The main passive elements of the MoEDAL detector do not require a trigger system, electronic readout, or online computerized data acquisition. The aim of this paper is to give an overview of the MoEDAL physics reach, which is largely complementary to the programs of the large multipurpose LHC detectors ATLAS and CMS. |
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Address |
[Acharya, B.; Alexandre, J.; Ellis, J. R.; Fairbairn, M.; Mavromatos, N. E.; Sakellariadou, M.; Sarkar, S.] Kings Coll London, Dept Phys, Theoret Particle Phys & Cosmol Grp, London WC2R 2LS, England, Email: jpinfold@ualberta.ca |
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Publisher |
World Scientific Publ Co Pte Ltd |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0217-751x |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000342220300004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1950 |
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Author |
ATLAS Collaboration (Aad, G. et al); Aparisi Pozo, J.A.; Bailey, A.J.; Cabrera Urban, S.; Cardillo, F.; Castillo Gimenez, V.; Costa, M.J.; Escobar, C.; Estrada Pastor, O.; Ferrer, A.; Fiorini, L.; Fullana Torregrosa, E.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Gonzalvo Rodriguez, G.R.; Guerrero Rojas, J.G.R.; Higon-Rodriguez, E.; Lacasta, C.; Lozano Bahilo, J.J.; Mamuzic, J.; Marti-Garcia, S.; Martinez Agullo, P.; Mitsou, V.A.; Moreno Llacer, M.; Navarro-Gonzalez, J.; Poveda, J.; Prades Ibañez, A.; Ruiz-Martinez, A.; Sabatini, P.; Salt, J.; Sayago Galvan, I.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valls Ferrer, J.A.; Villaplana Perez, M.; Vos, M. |
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Title |
The ATLAS Fast TracKer system |
Type |
Journal Article |
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Year |
2021 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
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Volume |
16 |
Issue |
7 |
Pages |
P07006 - 61pp |
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Keywords |
Modular electronics; Online farms and online filtering; Pattern recognition, cluster finding, calibration and fitting methods; Trigger concepts and systems (hardware and software) |
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Abstract |
The ATLAS Fast TracKer (FTK) was designed to provide full tracking for the ATLAS high-level trigger by using pattern recognition based on Associative Memory (AM) chips and fitting in high-speed field programmable gate arrays. The tracks found by the FTK are based on inputs from all modules of the pixel and silicon microstrip trackers. The as-built FTK system and components are described, as is the online software used to control them while running in the ATLAS data acquisition system. Also described is the simulation of the FTK hardware and the optimization of the AM pattern banks. An optimization for long-lived particles with large impact parameter values is included. A test of the FTK system with the data playback facility that allowed the FTK to be commissioned during the shutdown between Run 2 and Run 3 of the LHC is reported. The resulting tracks from part of the FTK system covering a limited eta-phi region of the detector are compared with the output from the FTK simulation. It is shown that FTK performance is in good agreement with the simulation. |
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Address |
[Duvnjak, D.; Jackson, P.; Kong, A. X. Y.; Oliver, J. L.; Ruggeri, T. A.; Sharma, A. S.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia |
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Publisher |
IOP Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1748-0221 |
ISBN |
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Conference |
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Notes |
WOS:000791152800006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5225 |
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Author |
Guerrero, M.; Olmo, G.J.; Rubiera-Garcia, D. |
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Title |
Double shadows of reflection-asymmetric wormholes supported by positive energy thin-shells |
Type |
Journal Article |
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Year |
2021 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
04 |
Issue |
4 |
Pages |
066 - 26pp |
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Keywords |
modified gravity; Wormholes; gravity |
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Abstract |
We consider reflection-asymmetric thin-shell wormholes within Palatini f(R) gravity using a matching procedure of two patches of electrovacuum space-times at a hypersurface (the shell) via suitable junction conditions. The conditions for having (linearly) stable wormholes supported by positive-energy matter sources are determined. We also identify some subsets of parameters able to locate the shell radius above the event horizon (when present) but below the photon sphere (on both sides). We illustrate with an specific example that such two photon spheres allow an observer on one of the sides of the wormhole to see another (circular) shadow in addition to the one generated by its own photon sphere, which is due to the photons passing above the maximum of the effective potential on its side and bouncing back across the throat due to a higher effective potential on the other side. We finally comment on the capability of these double shadows to seek for traces of new gravitational physics beyond that described by General Relativity. |
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Address |
[Guerrero, Merce; Rubiera-Garcia, Diego] Univ Complutense Madrid, Dept Fis Teor, E-28040 Madrid, Spain, Email: merguerr@ucm.es; |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000644501000029 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4823 |
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Author |
Afonso, V.I.; Olmo, G.J.; Rubiera-Garcia, D. |
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Title |
Scalar geons in Born-Infeld gravity |
Type |
Journal Article |
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Year |
2017 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
08 |
Issue |
8 |
Pages |
031 - 35pp |
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Keywords |
modified gravity; Wormholes |
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Abstract |
The existence of static, spherically symmetric, self-gravitating scalar field solutions in the context of Born-Infeld gravity is explored. Upon a combination of analytical approximations and numerical methods, the equations for a free scalar field (without a potential term) are solved, verifying that the solutions recover the predictions of General Relativity far from the center but finding important new effects in the central regions. We find two classes of objects depending on the ratio between the Schwarzschild radius and a length scale associated to the Born-Infeld theory: massive solutions have a wormhole structure, with their throat at r = 2 M, while for the lighter configurations the topology is Euclidean. The total energy density of these solutions exhibits a solitonic profile with a maximum peaked away from the center, and located at the throat whenever a wormhole exists. The geodesic structure and curvature invariants are analyzed for the various configurations considered. |
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Address |
[Afonso, V. I.] Univ Fed Campina Grande, Unidade Acad Fis, BR-58109970 Campina Grande, PB, Brazil, Email: viafonso@df.ufcg.edu.br; |
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Iop Publishing Ltd |
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English |
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1475-7516 |
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WOS:000408311900031 |
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3285 |
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Author |
Maso-Ferrando, A.; Sanchis-Gual, N.; Font, J.A.; Olmo, G.J. |
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Title |
Birth of baby universes from gravitational collapse in a modified-gravity scenario |
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Journal Article |
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2023 |
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Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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06 |
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6 |
Pages |
028 - 19pp |
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Keywords |
modified gravity; Wormholes |
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Abstract |
We consider equilibrium models of spherical boson stars in Palatini f (R) = R + CR2 gravity and study their collapse when perturbed. The Einstein-Klein-Gordon system is solved using a recently established correspondence in an Einstein frame representation. We find that, in that frame, the endpoint is a nonrotating black hole surrounded by a quasi -stationary cloud of scalar field. However, the dynamics in the f (R) frame is dramatically different. The innermost region of the collapsing object exhibits the formation of a finite -size, exponentially-expanding baby universe connected with the outer (parent) universe via a minimal area surface (a throat or umbilical cord). Our simulations indicate that this surface is at all times hidden inside a horizon, causally disconnecting the baby universe from observers above the horizon. The implications of our findings in other areas of gravitational physics are also discussed. |
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[Maso-Ferrando, Andreu; Olmo, Gonzalo J.] Univ Valencia, Ctr Mixto, CSIC, Dept Fis Teor, Valencia 46100, Spain, Email: andreu.maso@uv.es; |
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IOP Publishing Ltd |
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English |
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1475-7516 |
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WOS:001025474200010 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5577 |
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