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Author |
Sanjuan, R.; Nebot, M.; Chirico, N.; Mansky, L.M.; Belshaw, R. |
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Title |
Viral Mutation Rates |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of Virology |
Abbreviated Journal |
J. Virol. |
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Volume |
84 |
Issue |
19 |
Pages |
9733-9748 |
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Keywords  |
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Abstract |
Accurate estimates of virus mutation rates are important to understand the evolution of the viruses and to combat them. However, methods of estimation are varied and often complex. Here, we critically review over 40 original studies and establish criteria to facilitate comparative analyses. The mutation rates of 23 viruses are presented as substitutions per nucleotide per cell infection (s/n/c) and corrected for selection bias where necessary, using a new statistical method. The resulting rates range from 10(-8) to 10(-6) s/n/c for DNA viruses and from 10(-6) to 10(-4) s/n/c for RNA viruses. Similar to what has been shown previously for DNA viruses, there appears to be a negative correlation between mutation rate and genome size among RNA viruses, but this result requires further experimental testing. Contrary to some suggestions, the mutation rate of retroviruses is not lower than that of other RNA viruses. We also show that nucleotide substitutions are on average four times more common than insertions/deletions (indels). Finally, we provide estimates of the mutation rate per nucleotide per strand copying, which tends to be lower than that per cell infection because some viruses undergo several rounds of copying per cell, particularly double-stranded DNA viruses. A regularly updated virus mutation rate data set will be available at www.uv.es/rsanjuan/virmut. |
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Address |
[Sanjuan, Rafael] Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolutiva, Dept Genet, Valencia 46980, Spain, Email: rafael.sanjuan@uv.es |
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Publisher |
Amer Soc Microbiology |
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English |
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ISSN |
0022-538x |
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Conference |
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Notes |
ISI:000282641800008 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
371 |
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Author |
Doring, M.; Jido, D.; Oset, E. |
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Title |
Helicity amplitudes of the Lambda(1670) and two Lambda(1405) as dynamically generated resonances |
Type |
Journal Article |
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Year |
2010 |
Publication |
European Physical Journal A |
Abbreviated Journal |
Eur. Phys. J. A |
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Volume |
45 |
Issue |
3 |
Pages |
319-333 |
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Keywords |
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Abstract |
We determine the helicity amplitudes A(1/2) and radiative decay widths in the transition Lambda(1670) -> gamma Y (Y = Lambda or Sigma(0)). The Lambda(1670) is treated as a dynamically generated resonance in meson-baryon chiral dynamics. We obtain the radiative decay widths of the Lambda(1670) to gamma Lambda as 2 +/- 1 keV and to -gamma Sigma(0) as 120 +/- 50 keV. Also, the Q(2)-dependence of the helicity amplitudes A(1/2) is calculated. We find that the K Xi component in the Lambda(1670) structure, mainly responsible for the dynamical generation of this resonance, is also responsible for the significant suppression of the decay ratio Gamma(gamma A)/Gamma(gamma Sigma 0). A measurement of the ratio would, thus, provide direct access to the nature of the Lambda(1670). To compare the result for the Lambda(1670), we calculate the helicity amplitudes Lambda(1/2) for the two states of the Lambda(1405). Also, the analytic continuation of Feynman parameterized integrals of more complicated loop amplitudes to the complex plane is developed which allows for an internally consistent evaluation of A(1/2). |
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Address |
[Doering, M.] Forschungszentrum Julich, Inst Kernphys, D-52425 Julich, Germany, Email: m.doering@fz-jueiich.de |
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Publisher |
Springer |
Place of Publication |
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English |
Summary Language |
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Original Title |
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Edition |
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ISSN |
1434-6001 |
ISBN |
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Conference |
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Notes |
ISI:000281972900006 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
372 |
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Author |
CDF Collaboration (Aaltonen, T. et al); Cabrera, S. |
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Title |
Measurements of branching fraction ratios and CP asymmetries in B-+/- -> DCPK +/- decays in hadron collisions |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
81 |
Issue |
3 |
Pages |
031105 - 9pp |
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Keywords |
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Abstract |
We reconstruct B-+/- -> DK +/- decays in a data sample collected by the CDF II detector at the Tevatron collider corresponding to 1 fb(-1) of integrated luminosity. We select decay modes where the D meson decays to either K-pi(+) (flavor eigenstate) or K-K+, pi(-)pi(+) (CP-even eigenstates), and measure the direct CP asymmetry A(CP+) = 0.39 +/- 0.17(stat) +/- 0.04(syst), and the double ratio of CP-even to flavor eigenstate branching fractions RCP+ = 1.30 +/- 0.24(stat) +/- 0.12(syst). These measurements will improve the determination of the Cabibbo-Kobayashi-Maskawa angle gamma. They are performed here for the first time using data from hadron collisions. |
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Address |
[Aaltonen, T.; Mehtala, P.; Orava, R.; Osterberg, K.; Saarikko, H.; van Remortel, N.] Univ Helsinki, Div High Energy Phys, Dept Phys, FIN-00014 Helsinki, Finland |
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Corporate Author |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000275069000005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
297 |
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Author |
ATLAS Collaboration (Aad, G. et al); Cabrera Urban, S.; Castillo Gimenez, V.; Costa, M.J.; Ferrer, A.; Fiorini, L.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Hernandez Jimenez, Y.; Higon-Rodriguez, E.; Irles Quiles, A.; Kaci, M.; Lacasta, C.; Lacuesta, V.R.; Marti-Garcia, S.; Miñano, M.; Mitsou, V.A.; Moles-Valls, R.; Moreno Llacer, M.; Oliver Garcia, E.; Perez Garcia-Estañ, M.T.; Romero Adam, E.; Ros, E.; Salt, J.; Sanchez Martinez, V.; Solans, C.A.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valladolid Gallego, E.; Valls Ferrer, J.A.; Villaplana Perez, M.; Vos, M.; Wildauer, A. |
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Title |
Underlying event characteristics and their dependence on jet size of charged-particle jet events in pp collisions at root(s)=7 TeV with the ATLAS detector |
Type |
Journal Article |
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Year |
2012 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
86 |
Issue |
7 |
Pages |
072004 - 34pp |
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Keywords |
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Abstract |
Distributions sensitive to the underlying event are studied in events containing one or more chargedparticle jets produced in pp collisions at root s = 7 TeV with the ATLAS detector at the Large Hadron Collider (LHC). These measurements reflect 800 μb(-1) of data taken during 2010. Jets are reconstructed using the anti-k(t) algorithm with radius parameter R varying between 0.2 and 1.0. Distributions of the charged-particle multiplicity, the scalar sum of the transverse momentum of charged particles, and the average charged-particle p(T) are measured as functions of p(T)(jet) in regions transverse to and opposite the leading jet for 4 GeV < p(T)(jet) < 100 GeV. In addition, the R dependence of the mean values of these observables is studied. In the transverse region, both the multiplicity and the scalar sum of the transverse momentum at fixed p(T)(jet) vary significantly with R, while the average charged- particle transverse momentum has a minimal dependence on R. Predictions from several Monte Carlo tunes have been compared to the data; the predictions from Pythia 6, based on tunes that have been determined using LHC data, show reasonable agreement with the data, including the dependence on R. Comparisons with other generators indicate that additional tuning of soft-QCD parameters is necessary for these generators. The measurements presented here provide a testing ground for further development of the Monte Carlo models. |
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Address |
[Aad, G.; Ahles, F.; Barber, T.; Bernhard, R.; Bitenc, U.; Bruneliere, R.; Christov, A.; Consorti, V.; Fehling-Kaschek, M.; Flechl, M.; Glatzer, J.; Hartert, J.; Herten, G.; Horner, S.; Jakobs, K.; Janus, M.; Kollefrath, M.; Kononov, A. I.; Kuehn, S.; Lai, S.; Landgraf, U.; Lohwasser, K.; Ludwig, I.; Ludwig, J.; Lumb, D.; Mahboubi, K.; Mohr, W.; Nilsen, H.; Parzefall, U.; Rammensee, M.; Rave, T. C.; Runge, K.; Rurikova, Z.; Schmidt, E.; Schumacher, M.; Siegert, F.; Stoerig, K.; Sundermann, J. E.; Temming, K. K.; Thoma, S.; Tsiskaridze, V.; Venturi, M.; Vivarelli, I.; von Radziewski, H.; Anh, T. Vu; Warsinsky, M.; Weiser, C.; Werner, M.; Wiik-Fuchs, L. A. M.; Winkelmann, S.; Xie, S.; Zimmermann, S.] Univ Freiburg, Fak Math & Phys, D-79106 Freiburg, Germany |
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Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1550-7998 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000309585500002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1181 |
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Author |
CDF Collaboration (Aaltonen, T. et al); Cabrera, S. |
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Title |
Improved Search for a Higgs Boson Produced in Association with Z -> l(+)l(-) in p(p)over-bar Collisions at root s=1.96 TeV |
Type |
Journal Article |
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Year |
2010 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
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Volume |
105 |
Issue |
25 |
Pages |
251802 - 7pp |
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Keywords |
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Abstract |
We search for the standard model Higgs boson produced with a Z boson in 4: 1 fb(-1) of integrated luminosity collected with the CDF II detector at the Tevatron. In events consistent with the decay of the Higgs boson to a bottom-quark pair and the Z boson to electrons or muons, we set 95% credibility level upper limits on the ZH production cross section multiplied by the H -> b (b) over bar branching ratio. Improved analysis methods enhance signal sensitivity by 20% relative to previous searches. At a Higgs boson mass of 115 GeV/c(2) we set a limit of 5.9 times the standard model cross section. |
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Address |
[Aaltonen, T.; Brucken, E.; Devoto, F.; Mehtala, P.; Orava, R.] Univ Helsinki, Dept Phys, Div High Energy Phys, FIN-00014 Helsinki, Finland |
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Corporate Author |
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Thesis |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-9007 |
ISBN |
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Expedition |
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Conference |
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Notes |
ISI:000286750400004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
513 |
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