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Cabello, J., Etxebeste, A., Llosa, G., & Ziegler, S. I. (2015). Simulation study of PET detector limitations using continuous crystals. Phys. Med. Biol., 60(9), 3673–3694.
Abstract: Continuous crystals can potentially obtain better intrinsic detector spatial resolution compared to pixelated crystals, additionally providing depth of interaction (DoI) information from the light distribution. To achieve high performance sophisticated interaction position estimation algorithms are required. There are a number of algorithms in the literature applied to different crystal dimensions and different photodetectors. However, the different crystal properties and photodetector array geometries have an impact on the algorithm performance. In this work we analysed, through Monte Carlo simulations, different combinations of realistic crystals and photodetector parameters to better understand their influence on the interaction position estimation accuracy, with special emphasis on the DoI. We used an interaction position estimation based on an analytical model for the present work. Different photodetector granulation schemes were investigated. The impact of the number of crystal faces readout by photodetectors was studied by simulating scenarios with one and two photodetectors. In addition, crystals with different levels of reflection and aspect ratios (AR) were analysed. Results showed that the impact of photodetector granularity is mainly shown near the edges and specially in the corners of the crystal. The resulting intrinsic spatial resolution near the centre with a 12 x 12 x 10 mm(3) LYSO crystal was 0.7-0.9 mm, while the average spatial resolution calculated on the entire crystal was 0.77 +/- 0.18 mm for all the simulated geometries with one and two photodetectors. Having front and back photodetectors reduced the DoI bias (Euclidean distance between estimated DoI and real DoI) and improved the transversal resolution near the corners. In scenarios with one photodetector, small AR resulted in DoI inaccuracies for absorbed events at the entrance of the crystal. These inaccuracies were slightly reduced either by increasing the AR or reducing the amount of reflected light, and highly mitigated using two photodetectors. Using one photodetector, we obtained a piecewise DoI error model with a DoI resolution of 0.4-0.9 mm for a 1.2 AR crystal, and we observed that including a second photodetector or reducing the amount of reflections reduced the DoI bias but did not significantly improve the DoI resolution. Translating the piecewise DoI error model obtained in this study to image reconstruction we obtained a spatial resolution variability of 0.39 mm using 85% of the FoV, compared to 2.59 mm and 1.87 mm without DoI correction or with a dual layer system, respectively.
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Ferreira, M. N., & Papavassiliou, J. (2023). Gauge Sector Dynamics in QCD. Particles, 6(1), 312–363.
Abstract: The dynamics of the QCD gauge sector give rise to non-perturbative phenomena that are crucial for the internal consistency of the theory; most notably, they account for the generation of a gluon mass through the action of the Schwinger mechanism, the taming of the Landau pole, the ensuing stabilization of the gauge coupling, and the infrared suppression of the three-gluon vertex. In the present work, we review some key advances in the ongoing investigation of this sector within the framework of the continuum Schwinger function methods, supplemented by results obtained from lattice simulations.
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Aguilar, A. C., De Soto, F., Ferreira, M. N., Papavassiliou, J., Pinto-Gomez, F., Roberts, C. D., et al. (2023). Schwinger mechanism for gluons from lattice QCD. Phys. Lett. B, 841, 137906–8pp.
Abstract: Continuum and lattice analyses have revealed the existence of a mass-scale in the gluon two-point Schwinger function. It has long been conjectured that this expresses the action of a Schwinger mechanism for gauge boson mass generation in quantum chromodynamics (QCD). For such to be true, it is necessary and sufficient that a dynamically-generated, massless, colour-carrying, scalar gluon+gluon correlation emerges as a feature of the dressed three-gluon vertex. Working with results on elementary Schwinger functions obtained via the numerical simulation of lattice-regularised QCD, we establish with an extremely high level of confidence that just such a feature appears; hence, confirm the conjectured origin of the gluon mass scale.
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Albiol, A., Corbi, A., & Albiol, F. (2017). Automatic intensity windowing of mammographic images based on a perceptual metric. Med. Phys., 44(4), 1369–1378.
Abstract: Purpose: Initial auto-adjustment of the window level WL and width WW applied to mammographic images. The proposed intensity windowing (IW) method is based on the maximization of the mutual information (MI) between a perceptual decomposition of the original 12-bit sources and their screen displayed 8-bit version. Besides zoom, color inversion and panning operations, IW is the most commonly performed task in daily screening and has a direct impact on diagnosis and the time involved in the process. Methods: The authors present a human visual system and perception-based algorithm named GRAIL (Gabor-relying adjustment of image levels). GRAIL initially measures a mammogram's quality based on the MI between the original instance and its Gabor-filtered derivations. From this point on, the algorithm performs an automatic intensity windowing process that outputs the WL/WW that best displays each mammogram for screening. GRAIL starts with the default, high contrast, wide dynamic range 12-bit data, and then maximizes the graphical information presented in ordinary 8-bit displays. Tests have been carried out with several mammogram databases. They comprise correlations and an ANOVA analysis with the manual IW levels established by a group of radiologists. A complete MATLAB implementation of GRAIL is available at . Results: Auto-leveled images show superior quality both perceptually and objectively compared to their full intensity range and compared to the application of other common methods like global contrast stretching (GCS). The correlations between the human determined intensity values and the ones estimated by our method surpass that of GCS. The ANOVA analysis with the upper intensity thresholds also reveals a similar outcome. GRAIL has also proven to specially perform better with images that contain micro-calcifications and/or foreign X-ray-opaque elements and with healthy BI-RADS A-type mammograms. It can also speed up the initial screening time by a mean of 4.5 s per image. Conclusions: A novel methodology is introduced that enables a quality-driven balancing of the WL/WW of mammographic images. This correction seeks the representation that maximizes the amount of graphical information contained in each image. The presented technique can contribute to the diagnosis and the overall efficiency of the breast screening session by suggesting, at the beginning, an optimal and customized windowing setting for each mammogram.
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Gololo, M. G. D., Carrio Argos, F., & Mellado, B. (2022). Tile Computer-on-Module for the ATLAS Tile Calorimeter Phase-II upgrades. J. Instrum., 17(6), P06020–14pp.
Abstract: The Tile PreProcessor (TilePPr) is the core element of the Tile Calorimeter (TileCal) off-detector electronics for High-luminosity Large Hadron Collider (HL-LHC). The TilePPr comprises FPGA-based boards to operate and read out the TileCal on-detector electronics. The Tile Computer on Module (TileCoM) mezzanine is embedded within TilePPr to carry out three main functionalities. These include remote configuration of on-detector electronics and TilePPr FPGAs, interface the TilePPr with the ATLAS Trigger and Data Acquisition (TDAQ) system, and interfacing the TilePPr with the ATLAS Detector Control System (DCS) by providing monitoring data. The TileCoM is a 10-layer board with a Zynq UltraScale+ ZU2CG for processing data, interface components to integrate with TilePPr and the power supply to be connected to the Advanced Telecommunication Computing Architecture carrier. A CentOS embedded Linux is deployed on the TileCoM to implement the required functionalities for the HL-LHC. In this paper we present the hardware and firmware developments of the TileCoM system in terms of remote programming, interface with ATLAS TDAQ system and DCS system.
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Albiol, F., Corbi, A., & Albiol, A. (2017). Evaluation of modern camera calibration techniques for conventional diagnostic X-ray imaging settings. Radiol. Phys. Technol., 10(1), 68–81.
Abstract: We explore three different alternatives for obtaining intrinsic and extrinsic parameters in conventional diagnostic X-ray frameworks: the direct linear transform (DLT), the Zhang method, and the Tsai approach. We analyze and describe the computational, operational, and mathematical background differences for these algorithms when they are applied to ordinary radiograph acquisition. For our study, we developed an initial 3D calibration frame with tin cross-shaped fiducials at specific locations. The three studied methods enable the derivation of projection matrices from 3D to 2D point correlations. We propose a set of metrics to compare the efficiency of each technique. One of these metrics consists of the calculation of the detector pixel density, which can be also included as part of the quality control sequence in general X-ray settings. The results show a clear superiority of the DLT approach, both in accuracy and operational suitability. We paid special attention to the Zhang calibration method. Although this technique has been extensively implemented in the field of computer vision, it has rarely been tested in depth in common radiograph production scenarios. Zhang's approach can operate on much simpler and more affordable 2D calibration frames, which were also tested in our research. We experimentally confirm that even three or four plane-image correspondences achieve accurate focal lengths.
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Albiol, F., Corbi, A., & Albiol, A. (2019). Densitometric Radiographic Imaging With Contour Sensors. IEEE Access, 7, 18902–18914.
Abstract: We present the technical/physical foundations of a new imaging technique that combines ordinary radiographic information (generated by conventional X-ray settings) with the patient's volume to derive densitometric images. Traditionally, these images provide quantitative information about tissues densities. In our approach, they graphically enhance either soft or bony regions. After measuring the patient's volume with contour recognition devices, the physical traversed lengths within it (as the Roentgen beam intersects the patient) are calculated and pixel-wise associated with the original radiograph (X). In order to derive this map of lengths (L), the camera equations of the X-ray system and the contour sensor are determined. The patient's surface is also translated to the point-of-view of the X-ray beam and all its entrance/exit points are sought with the help of ray-casting methods. The derived L is applied to X as a physical operation (subtraction), obtaining soft tissue-(D-S) or bone-enhanced (D'(B)) figures. In the D-S type, the contained graphical information can be linearly mapped to the average electronic density (traversed by the X-ray beam). This feature represents an interesting proof-of-concept of associating density data to radiographs, but most important, their intensity histogram is objectively compressed, i.e., the dynamic range is more shrunk (compared against the corresponding X). This leads to other advantages: improvement in the visibility of border/edge areas (high gradient), extended manual window level/width manipulations during screening, and immediate correction of underexposed X instances. In the D-B' type, high-density elements are highlighted and easier to discern. All these results can be achieved with low-energy beam exposures, saving costs and dose. Future work will deepen this clinical side of our research. In contrast with other image-based modifiers, the proposed method is grounded on the measurement of a physical entity: the span of the X-ray beam within a body while undertaking a radiographic examination.
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Davier, M., Diaz-Calderon, D., Malaescu, B., Pich, A., Rodriguez-Sanchez, A., & Zhang, Z. (2023). The Euclidean Adler function and its interplay with Delta alpha(had)(QED) and alpha(s). J. High Energy Phys., 04(4), 067–57pp.
Abstract: Three different approaches to precisely describe the Adler function in the Euclidean regime at around 2 GeVs are available: dispersion relations based on the hadronic production data in e(+)e(-) annihilation, lattice simulations and perturbative QCD (pQCD). We make a comprehensive study of the perturbative approach, supplemented with the leading power corrections in the operator product expansion. All known contributions are included, with a careful assessment of uncertainties. The pQCD predictions are compared with the Adler functions extracted from ?a( QED)(had)(Q(2)), using both the DHMZ compilation of e(+)e(-) data and published lattice results. Taking as input the FLAG value of a(s), the pQCD Adler function turns out to be in good agreement with the lattice data, while the dispersive results lie systematically below them. Finally, we explore the sensitivity to a(s) of the direct comparison between the data-driven, lattice and QCD Euclidean Adler functions. The precision with which the renormalisation group equation can be tested is also evaluated.
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Sanchis-Lozano, M. A. (2022). Stringy Signals from Large-Angle Correlations in the Cosmic Microwave Background? Universe, 8(8), 396–13pp.
Abstract: We interpret the lack of large-angle temperature correlations and the even-odd parity imbalance observed in the cosmic microwave background (CMB) by COBE, WMAP and Planck satellite missions as a possible stringy signal ultimately stemming from a composite inflaton field (e.g., a fermionic condensate). Based on causality arguments and a Fourier analysis of the angular two-point correlation function, two infrared cutoffs k(min)(even,odd) (satisfying k(min)(even) similar or equal to 2k(min)(odd)) are introduced to the CMB power spectrum associated, respectively, with periodic and antiperiodic boundary conditions of the fermionic constituents (echoing the Neveu-Schwarz-Ramond model in superstring theory), without resorting to any particular model.
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Jueid, A., Kip, J., Ruiz de Austri, R., & Skands, P. (2023). Impact of QCD uncertainties on antiproton spectra from dark-matter annihilation. J. Cosmol. Astropart. Phys., 04(4), 068–15pp.
Abstract: Dark-matter particles that annihilate or decay can undergo complex sequences of processes, including strong and electromagnetic radiation, hadronisation, and hadron de-cays, before particles that are stable on astrophysical time scales are produced. Antiprotons produced in this way may leave footprints in experiments such as AMS-02. Several groups have reported an excess of events in the antiproton flux in the rigidity range of 10-20 GV. However, the theoretical modeling of baryon production is not straightforward and relies in part on phenomenological models in Monte Carlo event generators. In this work, we assess the impact of QCD uncertainties on the spectra of antiprotons from dark-matter annihila-tion. As a proof-of-principle, we show that for a two-parameter model that depends only on the thermally-averaged annihilation cross section ((o -v)) and the dark-matter mass (Mx), QCD uncertainties can affect the best-fit mass by up to ti 14% (with large uncertainties for large DM masses), depending on the choice of Mx and the annihilation channel (bb over bar or W+W-), and (o -v) by up to ti 10%. For comparison, changes to the underlying diffusion parameters are found to be within 1%-5%, and the results are also quite resilient to the choice of cosmic-ray propagation model. These findings indicate that QCD uncertainties need to be included in future DM analyses. To facilitate full-fledged analyses, we provide the spectra in tabulated form including QCD uncertainties and code snippets to perform mass interpolations and quick DM fits. The code can be found in this GitHub [1] repository.
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