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Author |
Candela-Juan, C.; Niatsetski, Y.; van der Laarse, R.; Granero, D.; Ballester, F.; Perez-Calatayud, J.; Vijande, J. |
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Title |
Design and characterization of a new high-dose-rate brachytherapy Valencia applicator for larger skin lesions |
Type |
Journal Article |
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Year |
2016 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
43 |
Issue |
4 |
Pages |
1639-1648 |
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Keywords  |
skin applicator; Valencia applicator; HDR brachytherapy; dosimetry; Monte Carlo |
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Abstract |
Purpose: The aims of this study were (i) to design a new high-dose-rate (HDR) brachytherapy applicator for treating surface lesions with planning target volumes larger than 3 cm in diameter and up to 5 cm in size, using the microSelectron-HDR or Flexitron afterloader (Elekta Brachytherapy) with a Ir-192 source; (ii) to calculate by means of the Monte Carlo (MC) method the dose distribution for the new applicator when it is placed against a water phantom; and (iii) to validate experimentally the dose distributions in water. Methods: The PENELOPE2008 MC code was used to optimize dwell positions and dwell times. Next, the dose distribution in a water phantom and the leakage dose distribution around the applicator were calculated. Finally, MC data were validated experimentally for a 192Ir mHDR-v2 source by measuring (i) dose distributions with radiochromic EBT3 films (ISP); (ii) percentage depth-dose (PDD) curve with the parallel-plate ionization chamber Advanced Markus (PTW); and (iii) absolute dose rate with EBT3 films and the PinPoint T31016 (PTW) ionization chamber. Results: The new applicator is made of tungsten alloy (Densimet) and consists of a set of interchangeable collimators. Three catheters are used to allocate the source at prefixed dwell positions with preset weights to produce a homogenous dose distribution at the typical prescription depth of 3 mm in water. The same plan is used for all available collimators. PDD, absolute dose rate per unit of air kerma strength, and off-axis profiles in a cylindrical water phantom are reported. These data can be used for treatment planning. Leakage around the applicator was also scored. The dose distributions, PDD, and absolute dose rate calculated agree within experimental uncertainties with the doses measured: differences of MC data with chamber measurements are up to 0.8% and with radiochromic films are up to 3.5%. Conclusions: The new applicator and the dosimetric data provided here will be a valuable tool in clinical practice, making treatment of large skin lesions simpler, faster, and safer. Also the dose to surrounding healthy tissues is minimal. |
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Address |
[Candela-Juan, C.; Perez-Calatayud, J.] La Fe Univ & Polytech Hosp, Dept Radiat Oncol, Valencia 46026, Spain, Email: ccanjuan@gmail.com |
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Publisher |
Amer Assoc Physicists Medicine Amer Inst Physics |
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English |
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ISSN |
0094-2405 |
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Conference |
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Notes |
WOS:000373711000007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2620 |
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Author |
Olmo, G.J.; Rubiera-Garcia, D.; Sanchez-Puente, A. |
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Title |
Impact of curvature divergences on physical observers in a wormhole space-time with horizons |
Type |
Journal Article |
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Year |
2016 |
Publication |
Classical and Quantum Gravity |
Abbreviated Journal |
Class. Quantum Gravity |
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Volume |
33 |
Issue |
11 |
Pages |
115007 - 12pp |
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Keywords |
Singularities; black holes; metric-affine geometry |
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Abstract |
The impact of curvature divergences on physical observers in a black hole space-time, which, nonetheless, is geodesically complete is investigated. This space-time is an exact solution of certain extensions of general relativity coupled to Maxwell's electrodynamics and, roughly speaking, consists of two Reissner-Nordstrom (or Schwarzschild or Minkowski) geometries connected by a spherical wormhole near the center. We find that, despite the existence of infinite tidal forces, causal contact is never lost among the elements making up the observer. This suggests that curvature divergences may not be as pathological as traditionally thought. |
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Address |
[Olmo, Gonzalo J.; Sanchez-Puente, A.] Univ Valencia, CSIC, Ctr Mixto, Dept Fis Teor, E-46100 Valencia, Spain, Email: gonzalo.olmo@csic.es; |
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Publisher |
Iop Publishing Ltd |
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English |
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ISSN |
0264-9381 |
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Notes |
WOS:000377442000010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2728 |
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Author |
Benitez, V. et al; Bernabeu, J.; Garcia, C.; Lacasta, C.; Marco, R.; Rodriguez, D.; Santoyo, D.; Solaz, C.; Soldevila, U. |
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Title |
Sensors for the End-cap prototype of the Inner Tracker in the ATLAS Detector Upgrade |
Type |
Journal Article |
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Year |
2016 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
833 |
Issue |
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Pages |
226-232 |
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Keywords |
Silicon radiation detectors; Strip sensors; HL-LHC; ATLAS Upgrade; Inner Tracker (ITk); End-cap |
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Abstract |
The new silicon microstrip sensors of the End-cap part of the HL-LHC ATLAS Inner Tracker (ITk) present a number of challenges due to their complex design features such as the multiple different sensor shapes, the varying strip pitch, or the built-In stereo angle. In order to investigate these specific problems, the “petalet” prototype was defined as a small End-cap prototype. The sensors for the petalet prototype include several new layout and technological solutions to investigate the issues, they have been tested in detail by the collaboration. The sensor description and detailed test results are presented in this paper. New software tools have been developed for the automatic layout generation of the complex designs. The sensors have been fabricated, characterized and delivered to the institutes in the collaboration for their assembly on petalet prototypes. This paper describes the lessons learnt from the design and tests of the new solutions implemented on these sensors, which are being used for the full petal sensor development. This has resulted in the ITIc strip, community acquiring the necessary expertise to develop the full End-cap structure, the petal. |
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Address |
[Benitez, V.; Ullan, M.; Quirion, D.; Pellegrini, G.; Fleta, C.; Lozano, M.] CSIC, CNM, IMB, Campus Univ Bellaterra, Barcelona 08193, Spain, Email: miguel.ullan@imb-cnm.csic.es |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Expedition |
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Conference |
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Notes |
WOS:000383818200032 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2816 |
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Author |
Casals, M.; Fabbri, A.; Martinez, C.; Zanelli, J. |
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Title |
Quantum dress for a naked singularity |
Type |
Journal Article |
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Year |
2016 |
Publication |
Physics Letters B |
Abbreviated Journal |
Phys. Lett. B |
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Volume |
760 |
Issue |
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Pages |
244-248 |
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Keywords |
Semiclassical gravity; Quantum backreaction; Cosmic censorship; Black holes; Naked singularities; BTZ |
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Abstract |
We investigate semiclassical backreaction on a conical naked singularity space-time with a negative cosmological constant in (2 + 1)-dimensions. In particular, we calculate the renormalized quantum stress-energy tensor for a conformally coupled scalar field on such naked singularity space-time. We then obtain the backreacted metric via the semiclassical Einstein equations. We show that, in the regime where the semiclassical approximation can be trusted, backreaction dresses the naked singularity with an event horizon, thus enforcing (weak) cosmic censorship. |
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Address |
[Casals, Marc] Ctr Brasileiro Pesquisas Fis, BR-22290180 Rio De Janeiro, Brazil, Email: mcasals@cbpf.br; |
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Publisher |
Elsevier Science Bv |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0370-2693 |
ISBN |
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Conference |
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Notes |
WOS:000382890500037 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2804 |
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Author |
Lauritsen, T. et al; Perez-Vidal, R.M. |
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Title |
Characterization of a gamma-ray tracking array: A comparison of GRETINA and Gammasphere using a Co-60 source |
Type |
Journal Article |
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Year |
2016 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
836 |
Issue |
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Pages |
46-56 |
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Keywords |
Segmented germanium detectors; Efficiency measurements; gamma-Ray tracking; Gammasphere; GRETINA; GRETA; gamma-Ray spectroscopy; Nuclear structure |
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Abstract |
In this paper; we provide a formalism for the characterization of tracking arrays with emphasis on the proper corrections required to extract their photopeak efficiencies and peak-to-total ratios. The methods are first applied to Gammasphere, a well characterized 4 pi array based on the principle of Compton suppression, and subsequently to GRETINA. The tracking efficiencies are then discussed and some guidelines as to what clustering angle to use in the tracking algorithm are presented. It was possible, using GEANT4 simulations, to scale the measured efficiencies up to the expected values for the full 4 pi implementation of GRETA. |
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Address |
[Lauritsen, T.; Zhu, S.; Ayangeakaa, A. D.; Carpenter, M. P.; Greene, J. P.; Janssens, R. V. F.; Khoo, T. L.; Seweryniak, D.] Argonne Natl Lab, 9700 S Cass Ave, Argonne, IL 60439 USA, Email: torben@anl.gov |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000385601400007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2830 |
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