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Author Viegas, R.; Roser, J.; Barrientos, L.; Borja-Lloret, M.; Casaña, J.V.; Lopez, J.G.; Jimenez-Ramos, M.C.; Hueso-Gonzalez, F.; Ros, A.; Llosa, G.
Title Characterization of a Compton camera based on the TOFPET2 ASIC Type Journal Article
Year 2023 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.
Volume 202 Issue Pages 110507 - 11pp
Keywords (up) Compton camera; Hadron therapy; LaBr3; PETsys TOFPET2; Silicon photomultipliers
Abstract The use of Compton cameras for medical imaging and its interest as a hadron therapy treatment monitoring has increased in the last decade with the development of silicon photomultipliers. MACACOp is a Compton camera prototype designed and assembled at the IRIS group of IFIC-Valencia. This Compton camera is based on monolithic Lanthanum (III) Bromide crystals and silicon photomultipliers, and employs the novel TOFPET2 ASIC as readout electronics. This system emerged as an alternative to MACACO II prototype, with the aim of improving its limited time resolution. To test the performance of the ASIC in a Compton camera setup, the prototype was characterized, both in laboratory and in-beam. A time resolution of 1.5 ns was obtained after time corrections, which improves greatly the performance of the MACACO II. Moreover, the results obtained at high photon energies demonstrate the ability of the system to obtain 1 mm displacements of the reconstructed spots. The results reinforce the potential of the system as a monitoring device for hadron therapy.
Address [Viegas, R.; Roser, J.; Barrientos, L.; Borja-Lloret, M.; Casana, J., V; Hueso-Gonzalez, F.; Ros, A.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Rita.Viegas@ific.uv.es
Corporate Author Thesis
Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0969-806x ISBN Medium
Area Expedition Conference
Notes WOS:000870840600006 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 5392
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Author Barrientos, L.; Borja-Lloret, M.; Etxebeste, A.; Muñoz, E.; Oliver, J.F.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.
Title Performance evaluation of MACACO II Compton camera Type Journal Article
Year 2021 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 1014 Issue Pages 165702 - 7pp
Keywords (up) Compton camera; Hadron therapy; LaBr3; Silicon photomultipliers
Abstract The IRIS group at IFIC-Valencia has developed a second version of a Compton camera prototype for hadron therapy treatment monitoring, with the aim of improving the performance with respect to its predecessor. The system is composed of three Lanthanum (III) bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs). The detector energy resolution has been improved to 5.6% FWHM at 511 keV and an angular resolution of 8.0 degrees has been obtained. Images of a Na-22 point-like source have been reconstructed selecting two and three interaction events. Moreover, the experimental data have been reproduced with Monte Carlo simulations using a Compton camera module (CCMod) in GATE v8.2 obtaining a good correlation.
Address [Barrientos, L.; Borja-Lloret, M.; Munoz, E.; Oliver, J. F.; Ros, A.; Roser, J.; Senra, C.; Viegas, R.; Llosa, G.] Univ Valencia, Inst Fis Corpuscular, CSIC, Valencia, Spain, Email: lbarrien@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000701263400010 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4976
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Author Barrientos, L.; Borja-Lloret, M.; Casana, J.V.; Hueso-Gonzalez, F.; Ros, A.; Roser, J.; Senra, C.; Solaz, C.; Viegas, R.; Llosa, G.
Title System characterization and performance studies with MACACO III Compton camera Type Journal Article
Year 2023 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.
Volume 208 Issue Pages 110922 - 13pp
Keywords (up) Compton camera; Scintillator crystals; Silicon photomultipliers
Abstract The IRIS group of IFIC-Valencia has developed a Compton camera prototype. The system detectors are made of Lanthanum (III) bromide scintillator crystals coupled to silicon photomultipliers. Two models of silicon photomultipliers arrays with different micro pixel pitch (25 and 50 μm) have been chosen as possible candidates to improve the response of the new system. Characterization studies with a 22Na point-like source have indicated that the 25 μm photodetector provided better performance in terms of energy resolution (5.2% FWHM at 511 keV) and angular resolution (6.9 degrees FWHM at 1275 keV), and more stability with temperature variations. In addition, MACACO III imaging capabilities have been assessed using a structure composed of thirty-seven 22Na point-like sources. Furthermore, in order to evaluate possible ways of improving the system performance, several studies have been carried out by means of simulations both in realistic and performance improved conditions. In this work, the system performance is evaluated for its future application in different areas.
Address [Barrientos, L.; Borja-Lloret, M.; Casana, J. V.; Hueso-Gonzalez, F.; Ros, A.; Roser, J.; Senra, C.; Solaz, C.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IF, Valencia, Spain, Email: Luis.Barrientos@ific.uv.es;
Corporate Author Thesis
Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0969-806x ISBN Medium
Area Expedition Conference
Notes WOS:000962800400001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 5511
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Author Llosa, G.
Title SiPM-based Compton cameras Type Journal Article
Year 2019 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 926 Issue Pages 148-152
Keywords (up) Compton camera; Silicon photomultiplier (SiPM)
Abstract Compton cameras have been developed for almost fifty years in various fields (astronomy, medical imaging, safety and industrial inspections, etc.), employing different types of detectors. Their potential use has gained renewed interest with the emergence of high light yield scintillator crystals and silicon photomultipliers (SiPMs). This combination provides good performance and operation simplicity at an affordable cost, raising again the interest in this type of systems. SiPM-based Compton cameras are being assessed for diverse applications with promising results.
Address [Llosa, G.] UVEG, CSIC, Inst Fis Corpuscular IFIC, C Catedrat Beltran 2, E-46980 Valencia, Spain, Email: llosa@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000461775500011 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 3951
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Author Muñoz, E.; Barrio, J.; Etxebeste, A.; Ortega, P.G.; Lacasta, C.; Oliver, J.F.; Solaz, C.; Llosa, G.
Title Performance evaluation of MACACO: a multilayer Compton camera Type Journal Article
Year 2017 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 62 Issue 18 Pages 7321-7341
Keywords (up) Compton imaging; Compton camera; continuous LaBr3 crystal; silicon photomultiplier; hadron therapy
Abstract Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm.
Address [Munoz, Enrique; Barrio, John; Etxebeste, Ane; Ortega, Pablo G.; Lacasta, Carlos; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000408229900003 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3253
Permanent link to this record