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Beaulieu, L., Ballester, F., Granero, D., Tedgren, A. C., Haworth, A., Lowenstein, J. R., et al. (2023). AAPM WGDCAB Report 372: A joint AAPM, ESTRO, ABG, and ABS report on commissioning of model-based dose calculation algorithms in brachytherapy. Med. Phys., 50(8), e946–e960.
Abstract: The introduction of model-based dose calculation algorithms (MBDCAs) in brachytherapy provides an opportunity for a more accurate dose calculation and opens the possibility for novel, innovative treatment modalities. The joint AAPM, ESTRO, and ABG Task Group 186 (TG-186) report provided guidance to early adopters. However, the commissioning aspect of these algorithms was described only in general terms with no quantitative goals. This report, from the Working Group on Model-Based Dose Calculation Algorithms in Brachytherapy, introduced a field-tested approach to MBDCA commissioning. It is based on a set of well-characterized test cases for which reference Monte Carlo (MC) and vendor-specific MBDCA dose distributions are available in a Digital Imaging and Communications in Medicine-Radiotherapy (DICOM-RT) format to the clinical users. The key elements of the TG-186 commissioning workflow are now described in detail, and quantitative goals are provided. This approach leverages the well-known Brachytherapy Source Registry jointly managed by the AAPM and the Imaging and Radiation Oncology Core (IROC) Houston Quality Assurance Center (with associated links at ESTRO) to provide open access to test cases as well as step-by-step user guides. While the current report is limited to the two most widely commercially available MBDCAs and only for Ir-192-based afterloading brachytherapy at this time, this report establishes a general framework that can easily be extended to other brachytherapy MBDCAs and brachytherapy sources. The AAPM, ESTRO, ABG, and ABS recommend that clinical medical physicists implement the workflow presented in this report to validate both the basic and the advanced dose calculation features of their commercial MBDCAs. Recommendations are also given to vendors to integrate advanced analysis tools into their brachytherapy treatment planning system to facilitate extensive dose comparisons. The use of the test cases for research and educational purposes is further encouraged.
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Nadal-Gisbert, S., Navarro-Salas, J., & Pla, S. (2023). Low-energy states and CPT invariance at the big bang. Phys. Rev. D, 107(8), 085018–16pp.
Abstract: In this paper, we analyze the quantum vacuum in a radiation-dominated and CPT -invariant universe by further imposing the quantum states to be ultraviolet regular i.e., satisfying the Hadamard/adiabatic condition. For scalar fields, this is enforced by constructing the vacuum via the states of low-energy proposal. For spin -12 fields, we extend this proposal for a FLRW spacetime and apply it for the radiation-dominated and CPT -invariant universe. We focus on minimizing the smeared energy density around the big bang and give strong evidence that the resulting states satisfy the Hadamard/adiabatic condition. These states are then self -consistent candidates as effective big bang quantum vacuum from the field theory perspective.
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Coloma, P., Gonzalez-Garcia, M. C., Maltoni, M., Pinheiro, J. P., & Urrea, S. (2023). Global constraints on non-standard neutrino interactions with quarks and electrons. J. High Energy Phys., 08(8), 032–42pp.
Abstract: We derive new constraints on effective four-fermion neutrino non-standard interactions with both quarks and electrons. This is done through the global analysis of neutrino oscillation data and measurements of coherent elastic neutrino-nucleus scattering (CE & nu;NS) obtained with different nuclei. In doing so, we include not only the effects of new physics on neutrino propagation but also on the detection cross section in neutrino experiments which are sensitive to the new physics. We consider both vector and axial-vector neutral-current neutrino interactions and, for each case, we include simultaneously all allowed effective operators in flavour space. To this end, we use the most general parametrization for their Wilson coefficients under the assumption that their neutrino flavour structure is independent of the charged fermion participating in the interaction. The status of the LMA-D solution is assessed for the first time in the case of new interactions taking place simultaneously with up quarks, down quarks, and electrons. One of the main results of our work are the presently allowed regions for the effective combinations of non-standard neutrino couplings, relevant for long-baseline and atmospheric neutrino oscillation experiments.
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Blennow, M., Fernandez-Martinez, E., Hernandez-Garcia, J., Lopez-Pavon, J., Marcano, X., & Naredo-Tuero, D. (2023). Bounds on lepton non-unitarity and heavy neutrino mixing. J. High Energy Phys., 08(8), 030–41pp.
Abstract: We present an updated and improved global fit analysis of current flavour and electroweak precision observables to derive bounds on unitarity deviations of the leptonic mixing matrix and on the mixing of heavy neutrinos with the active flavours. This new analysis is motivated by new and updated experimental results on key observables such as V-ud, the invisible decay width of the Z boson and the W boson mass. It also improves upon previous studies by considering the full correlations among the different observables and explicitly calibrating the test statistic, which may present significant deviations from a & chi;(2) distribution. The results are provided for three different Type-I seesaw scenarios: the minimal scenario with only two additional right-handed neutrinos, the next to minimal one with three extra neutrinos, and the most general one with an arbitrary number of heavy neutrinos that we parametrise via a generic deviation from a unitary leptonic mixing matrix. Additionally, we also analyze the case of generic deviations from unitarity of the leptonic mixing matrix, not necessarily induced by the presence of additional neutrinos. This last case relaxes some correlations among the parameters and is able to provide a better fit to the data. Nevertheless, inducing only leptonic unitarity deviations avoiding both the correlations implied by the right-handed neutrino extension as well as more strongly constrained operators is challenging and would imply significantly more complex UV completions.
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Sandner, S., Escudero, M., & Witte, S. J. (2023). Precision CMB constraints on eV-scale bosons coupled to neutrinos. Eur. Phys. J. C, 83(8), 709–12pp.
Abstract: The cosmic microwave background (CMB) has proven to be an invaluable tool for studying the properties and interactions of neutrinos, providing insight not only into the sum of neutrino masses but also the free streaming nature of neutrinos prior to recombination. The CMB is a particularly powerful probe of new eV-scale bosons interacting with neutrinos, as these particles can thermalizewith neutrinos via the inverse decay process, v (v) over bar -> X, and suppress neutrino free streaming near recombination – even for couplings as small as lambda(v) similar to O(10(-13)). Here, we revisit CMB constraints on such bosons, improving upon a number of approximations previously adopted in the literature and generalizing the constraints to a broader class of models. This includes scenarios in which the boson is either spin-0 or spin-1, the number of interacting neutrinos is either N-int = 1, 2 or 3, and the case in which a primordial abundance of the species is present. We apply these bounds to well-motivatedmodels, such as the singlet majoron model or a light U(1) L-mu- L-t gauge boson, and find that they represent the leading constraints for masses m(X) similar to 1 eV. Finally, we revisit the extent to which neutrinophilic bosons can ameliorate the Hubble tension, and find that recent improvements in the understanding of how such bosons damp neutrino free streaming reduces the previously found success of this proposal.
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