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Botella, F. J., Cornet-Gomez, F., & Nebot, M. (2020). Electron and muon g-2 anomalies in general flavor conserving two-Higgs-doublet models. Phys. Rev. D, 102(3), 035023–19pp.
Abstract: In general two-Higgs-doublet models (2HDMs) without scalar flavor changing neutral couplings (SFCNC) in the lepton sector, the electron, muon, and tau interactions can be decoupled in a robust framework, stable under renormalization group evolution. In this framework, the breaking of lepton flavor universality (LFU) goes beyond the mass proportionality, opening the possibility to accommodate in a simple manner a different behavior among charged leptons. We analyze simultaneously the electron and muon (g – 2) anomalies in the context of these general flavor conserving models in the leptonic sector (gtlFC). We consider two different models, I-gtlFC and II-gelFC, in which the quark Yukawa couplings coincide, respectively, with the ones in type I and in type II 2HDMs. We find two types of solutions that fully reproduce both (g – 2) anomalies, and which are compatible with experimental constraints from LEP and LHC, from LFU, from flavor and electroweak physics, and with theoretical constraints in the scalar sector. In the first type of solution, all the new scalars have masses in the 1-2.5 TeV range, the vacuum expectation values (vevs) of both doublets are quite similar in magnitude, and both anomalies are dominated by two loop Barr-Zee contributions. This solution appears in both models. There is a second type of solution, where one loop contributions are dominant in the muon anomaly, all new scalars have masses below 1 TeV, and the ratio of vevs is in the range 10-100. The second neutral scalar H is the lighter among the new scalars, with a mass in the 210-390 GeV range while the pseudoscalar A is the heavier, with a mass in the range 400-900 GeV. The new charged scalar H-+/- is almost degenerate either with the scalar or with the pseudoscalar. This second type of solution only appears in the I-gelFC model. Both solutions require the soft breaking of the Z(2) symmetry of the Higgs potential.
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Sanjuan, R., Nebot, M., Peris, J. B., & Alcami, J. (2013). Immune Activation Promotes Evolutionary Conservation of T-Cell Epitopes in HIV-1. PLoS. Biol., 11(4), e1001523–10pp.
Abstract: The immune system should constitute a strong selective pressure promoting viral genetic diversity and evolution. However, HIV shows lower sequence variability at T-cell epitopes than elsewhere in the genome, in contrast with other human RNA viruses. Here, we propose that epitope conservation is a consequence of the particular interactions established between HIV and the immune system. On one hand, epitope recognition triggers an anti-HIV response mediated by cytotoxic T-lymphocytes (CTLs), but on the other hand, activation of CD4(+) helper T lymphocytes (T-H cells) promotes HIV replication. Mathematical modeling of these opposite selective forces revealed that selection at the intrapatient level can promote either T-cell epitope conservation or escape. We predict greater conservation for epitopes contributing significantly to total immune activation levels (immunodominance), and when T-H cell infection is concomitant to epitope recognition (transinfection). We suggest that HIV-driven immune activation in the lymph nodes during the chronic stage of the disease may offer a favorable scenario for epitope conservation. Our results also support the view that some pathogens draw benefits from the immune response and suggest that vaccination strategies based on conserved T-H epitopes may be counterproductive.
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Bernabeu, J., Botella, F. J., Nebot, M., & Segarra, A. (2022). B-0 – (B)over-bar(0) entanglement for an ideal experiment for the direct CP violation phi(3)/gamma phase. Phys. Rev. D, 106(5), 054026–7pp.
Abstract: B-0-(B) over bar0 entanglement offers a conceptual alternative to the single charged B-decay asymmetry for the measurement of the direct CP-violating gamma/phi(3) phase. With f = J/Psi(L); J/Psi K-S and g = (pi pi)(0); (rho(L)rho(L))(0), the 16 time-ordered double-decay rate intensities to (f, g) depend on the relative phase between the f- and g-decay amplitudes given by gamma at tree level. Several constraining consistencies appear. An intrinsic accuracy of the method at the level of +/- 1 degrees could be achievable at Belle-II with an improved determination of the penguin amplitude to g channels from existing facilities.
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Bernabeu, J., Botella, F. J., & Nebot, M. (2016). Genuine T, CP, CPT asymmetry parameters for the entangled B-d system. J. High Energy Phys., 06(6), 100–24pp.
Abstract: The precise connection between the theoretical T, CP, CPT asymmetries, in terms of transition probabilities between the filtered neutral meson B-d states, and the experimental asymmetries, in terms of the double decay rate intensities for Flavour-CP eigenstate decay products in a B-d-factory of entangled states, is established. This allows the identification of genuine Asymmetry Parameters in the time distribution of the asymmetries and their measurability by disentangling genuine and possible fake terms. We express the nine asymmetry parameters three different observables for each one of the three symmetries in terms of the ingredients of the Weisskopf-Wigner dynamical description of the entangled B-d-meson states and we obtain a global fit to their values from the BaBar collaboration experimental results. The possible fake terms are all compatible with zero and the information content of the nine asymmetry parameters is indeed different. The non -vanishing Delta l(c)(T) = 0.687 +/- 0.020 and Delta l(c)(CP) = 0.680 +/- 0.021 are impressive separate direct evidence of Time -Reversal -violation and CP-violation in these transitions and compatible with Standard Model expectations. An intriguing 2 sigma effect for the Re(theta) parameter responsible of CPT -violation appears which, interpreted as an upper limit, leads to vertical bar M (B) over baro (B) over baro vertical bar MBoBo < 4.0 x 10(-5) eV at 95% C.L. for the diagonal flavour terms of the mass matrix. It contributes to the CP-violating Delta l(c)(CP) asymmetry parameter in an unorthodox manner – in its cos(Delta M t) time dependence-, and it is accessible in facilities with non-entangled B-d's, like the LHCb experiment.
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Botella, F. J., Branco, G. C., Nebot, M., Rebelo, M. N., & Silva-Marcos, J. I. (2017). Vector-like quarks at the origin of light quark masses and mixing. Eur. Phys. J. C, 77(6), 408–14pp.
Abstract: We show how a novel fine-tuning problem present in the Standard Model can be solved through the introduction of a Z(6) flavour symmetry, together with three Q = -1/3 quarks, three Q = 2/3 quarks, as well as a complex singlet scalar. The Z(6) symmetry is extended to the additional fields and it is an exact symmetry of the Lagrangian, only softly broken in the scalar potential, in order to avoid the domain-wall problem. Specific examples are given and a phenomenological analysis of the main features of the model is presented. It is shown that even for vector-like quarks with masses accessible at the LHC, one can have realistic quark masses and mixing, while respecting the strict constraints on processes arising from flavour changing neutral currents. The vector-like quark decay channels are also described.
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