Abstract: Purpose: In order to facilitate a smooth transition for brachytherapy dose calculations from the American Association of Physicists in Medicine (AAPM) Task Group No. 43 (TG-43) formalism to model-based dose calculation algorithms (MBDCAs), treatment planning systems (TPSs) using a MBDCA require a set of well-defined test case plans characterized by Monte Carlo (MC) methods. This also permits direct dose comparison to TG-43 reference data. Such test case plans should be made available for use in the software commissioning process performed by clinical end users. To this end, a hypothetical, generic high-dose rate (HDR) Ir-192 source and a virtual water phantom were designed, which can be imported into a TPS. Methods: A hypothetical, generic HDR Ir-192 source was designed based on commercially available sources as well as a virtual, cubic water phantom that can be imported into any TPS in DICOM format. The dose distribution of the generic Ir-192 source when placed at the center of the cubic phantom, and away from the center under altered scatter conditions, was evaluated using two commercial MBDCAs [Oncentra (R) Brachy with advanced collapsed-cone engine (ACE) and BrachyVision AcuRos (TM)]. Dose comparisons were performed using state-of-the-art MC codes for radiation transport, including ALGEBRA, BrachyDose, GEANT4, MCNP5, MCNP6, and pENELopE2008. The methodologies adhered to recommendations in the AAPM TG-229 report on high-energy brachytherapy source dosimetry. TG-43 dosimetry parameters, an along-away dose-rate table, and primary and scatter separated (PSS) data were obtained. The virtual water phantom of (201)(3) voxels (1 mm sides) was used to evaluate the calculated dose distributions. Two test case plans involving a single position of the generic HDR Ir-192 source in this phantom were prepared: (i) source centered in the phantom and (ii) source displaced 7 cm laterally from the center. Datasets were independently produced by different investigators. MC results were then compared against dose calculated using TG-43 and MBDCA methods. Results: TG-43 and PSS datasets were generated for the generic source, the PSS data for use with the ACE algorithm. The dose-rate constant values obtained from seven MC simulations, performed independently using different codes, were in excellent agreement, yielding an average of 1.1109 +/- 0.0004 cGy/(h U) (k = 1, Type A uncertainty). MC calculated dose-rate distributions for the two plans were also found to be in excellent agreement, with differences within type A uncertainties. Differences between commercial MBDCA and MC results were test, position, and calculation parameter dependent. On average, however, these differences were within 1% for ACUROS and 2% for ACE at clinically relevant distances. Conclusions: A hypothetical, generic HDR Ir-192 source was designed and implemented in two commercially available TPSs employing different MBDCAs. Reference dose distributions for this source were benchmarked and used for the evaluation of MBDCA calculations employing a virtual, cubic water phantom in the form of a CT DICOM image series. The implementation of a generic source of identical design in all TPSs using MBDCAs is an important step toward supporting univocal commissioning procedures and direct comparisons between TPSs.

Abstract: We make use of a self-consistent quark-model based study of four-quark charmonium-like states to interpret recent charmonium experimental data. We conclude that there exists a D*(D) over bar* meson-meson molecule with quantum numbers (I-G) J(PC) = (1(-))2(++). Our study confirms the presence of charged charmonium-like resonances on the excited charmonium spectrum. We find support from recent experimental data by the Belle Collaboration [R. Mizuk et al. (Belle Collaboration), Phys. Rev. D 78, 072004 (2008)]. Confirmation of the experimental data by the Belle Collaboration and the determination of the quantum numbers of the new structures would help in discriminating among different theoretical models and would give further support to the theoretical analysis of T. Fernandez-Carames, A. Valcarce, and J. Vijande [Phys. Rev. Lett. 103, 222001 (2009)].

Abstract: This paper provides results for the spectra of triply charmed and bottom baryons based on a constituent-quark model approach. We take advantage of the assumption that potential models are expected to describe triply heavy baryons to a similar degree of accuracy as the successful results obtained in the charmonium and bottomonium sectors. The high precision calculation of the ground state and positive and negative parity excited states recently reported by nonperturbative lattice QCD provides us with a unique opportunity to confront model predictions with the data. This comparison may also help to build a bridge between two difficult to reconcile lattice QCD results, namely, the lattice SU(3) QCD static three-quark potential and the recent results of nonperturbative lattice QCD for the triply heavy baryon spectra.