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Author Oliver, S.; Gimenez-Alventosa, V.; Berumen, F.; Gimenez, V.; Beaulieu, L.; Ballester, F.; Vijande, J.
Title Benchmark of the PenRed Monte Carlo framework for HDR brachytherapy Type Journal Article
Year 2023 Publication Zeitschrift für Medizinische Physik Abbreviated Journal Z. Med. Phys.
Volume 33 Issue (down) 4 Pages 511-528
Keywords Monte Carlo; PenRed; Brachytherapy; DICOM; Medical physics
Abstract Purpose: The purpose of this study is to validate the PenRed Monte Carlo framework for clinical applications in brachytherapy. PenRed is a C++ version of Penelope Monte Carlo code with additional tallies and utilities. Methods and materials: Six benchmarking scenarios are explored to validate the use of PenRed and its improved bachytherapy-oriented capabilities for HDR brachytherapy. A new tally allowing the evaluation of collisional kerma for any material using the track length kerma estimator and the possibility to obtain the seed positions, weights and directions processing directly the DICOM file are now implemented in the PenRed distribution. The four non-clinical test cases developed by the Joint AAPM-ESTRO-ABG-ABS WG-DCAB were evaluated by comparing local and global absorbed dose differences with respect to established reference datasets. A prostate and a palliative lung cases, were also studied. For them, absorbed dose ratios, global absorbed dose differences, and cumulative dose-volume histograms were obtained and discussed. Results: The air-kerma strength and the dose rate constant corresponding to the two sources agree with the reference datatests within 0.3% (Sk) and 0.1% (K). With respect to the first three WG-DCAB test cases, more than 99.8% of the voxels present local (global) differences within +/- 1%(+/- 0.1%) of the reference datasets. For test Case 4 reference dataset, more than 94.9%(97.5%) of voxels show an agreement within +/- 1%(+/- 0.1%), better than similar benchmarking calculations in the literature. The track length kerma estimator scorer implemented increases the numerical efficiency of brachytherapy calculations two orders of magnitude, while the specific brachytherapy source allows the user to avoid the use of error-prone intermediate steps to translate the DICOM information into the simulation. In both clinical cases, only minor absorbed dose differences arise in the low-dose isodoses. 99.8% and 100% of the voxels have a global absorbed dose difference ratio within +/- 0.2%for the prostate and lung cases, respectively. The role played by the different segmentation and composition material in the bone structures was discussed, obtaining negligible absorbed dose differ-ences. Dose-volume histograms were in agreement with the reference data.Conclusions: PenRed incorporates new tallies and utilities and has been validated for its use for detailed and precise high-dose-rate brachytherapy simulations.
Address [Oliver, S.] Univ Politecn Valencia, Inst Segur Ind, Radiofis & Medioambiental ISIRYM, Camide Vera s n, Valencia 46022, Spain, Email: sanolgi@upvnet.upv.es
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0939-3889 ISBN Medium
Area Expedition Conference
Notes WOS:001137118400001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5885
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Author Etxebeste, A.; Barrio, J.; Bernabeu, J.; Lacasta, C.; Llosa, G.; Muñoz, E.; Ros, A.; Oliver, J.F.
Title Study of sensitivity and resolution for full ring PET prototypes based on continuous crystals and analytical modeling of the light distribution Type Journal Article
Year 2019 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 64 Issue (down) 3 Pages 035015 - 17pp
Keywords continuous crystals; NEMA NU 4-2008; positron emission tomography (PET); Monte Carlo simulations; image reconstruction; depth of interaction
Abstract Sensitivity and spatial resolution are the main parameters to maximize in the performance of a PET scanner. For this purpose, detectors consisting of a combination of continuous crystals optically coupled to segmented photodetectors have been employed. With the use of continuous crystals the sensitivity is increased with respect to the pixelated crystals. In addition, spatial resolution is no longer limited to the crystal size. The main drawback is the difficulty in determining the interaction position. In this work, we present the characterization of the performance of a full ring based on cuboid continuous crystals coupled to SiPMs. To this end, we have employed the simulations developed in a previous work for our experimental detector head. Sensitivity could be further enhanced by using tapered crystals. This enhancement is obtained by increasing the solid angle coverage, reducing the wedge-shaped gaps between contiguous detectors. The performance of the scanners based on both crystal geometries was characterized following NEMA NU 4-2008 standardized protocol in order to compare them. An average sensitivity gain over the entire axial field of view of 13.63% has been obtained with tapered geometry while similar performance of the spatial resolution has been proven with both scanners. The activity at which NECR and true peak occur is smaller and the peak value is greater for tapered crystals than for cuboid crystals. Moreover, a higher degree of homogeneity was obtained in the sensitivity map due to the tighter packing of the crystals, which reduces the gaps and results in a better recovery of homogeneous regions than for the cuboid configuration. Some of the results obtained, such as spatial resolution, depend on the interaction position estimation and may vary if other method is employed.
Address [Etxebeste, Ane; Barrio, John; Bernabeu, Jose; Lacasta, Carlos; Llosa, Gabriela; Munoz, Enrique; Ros, Ana; Oliver, Josef F.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: ane.etxebeste@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000457182500004 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3897
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Author Romero-Barrientos, J.; Marquez Damian, J.I.; Molina, F.; Zambra, M.; Aguilera, P.; Lopez-Usquiano, F.; Parra, B.; Ruiz, A.
Title Calculation of kinetic parameters beta eff and L with modified open source Monte Carlo code OpenMC(TD) Type Journal Article
Year 2022 Publication Nuclear Engineering and Technology Abbreviated Journal Nucl. Eng. Technol.
Volume 54 Issue (down) 3 Pages 811-816
Keywords OpenMC; Monte Carlo; Kinetic parameters; Open source; Neutron generation time; Effective delayed neutron fraction
Abstract This work presents the methodology used to expand the capabilities of the Monte Carlo code OpenMC for the calculation of reactor kinetic parameters: effective delayed neutron fraction beff and neutron generation time L. The modified code, OpenMC(Time-Dependent) or OpenMC(TD), was then used to calculate the effective delayed neutron fraction by using the prompt method, while the neutron generation time was estimated using the pulsed method, fitting L to the decay of the neutron population. OpenMC(TD) is intended to serve as an alternative for the estimation of kinetic parameters when licensed codes are not available. The results obtained are compared to experimental data and MCNP calculated values for 18 benchmark configurations.
Address [Romero-Barrientos, J.; Molina, F.; Zambra, M.; Aguilera, P.; Lopez-Usquiano, F.; Ruiz, A.] Comis Chilena Energia Nucl, Santiago 12501, Chile, Email: romeroj@uchile.cl
Corporate Author Thesis
Publisher Korean Nuclear Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1738-5733 ISBN Medium
Area Expedition Conference
Notes WOS:000766649800004 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5172
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Author Valdes-Cortez, C.; Ballester, F.; Vijande, J.; Gimenez, V.; Gimenez-Alventosa, V.; Perez-Calatayud, J.; Niatsetski, Y.; Andreo, P.
Title Depth-dose measurement corrections for the surface electronic brachytherapy beams of an Esteya(R) unit: a Monte Carlo study Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue (down) 24 Pages 245026 - 12pp
Keywords electronic brachytherapy; eBT; dosimetry; ionization chamber; Monte Carlo
Abstract Three different correction factors for measurements with the parallel-plate ionization chamber PTW T34013 on the Esteya electronic brachytherapy unit have been investigated. This chamber type is recommended by AAPM TG-253 for depth-dose measurements in the 69.5 kV x-ray beam generated by the Esteya unit. Monte Carlo simulations using the PENELOPE-2018 system were performed to determine the absorbed dose deposited in water and in the chamber sensitive volume at different depths with a Type A uncertainty smaller than 0.1%. Chamber-to-chamber differences have been explored performing measurements using three different chambers. The range of conical applicators available, from 10 to 30 mm in diameter, has been explored. Using a depth-independent global chamber perturbation correction factor without a shift of the effective point of measurement yielded differences between the absorbed dose to water and the corrected absorbed dose in the sensitive volume of the chamber of up to 1% and 0.6% for the 10 mm and 30 mm applicators, respectively. Calculations using a depth-dependent perturbation factor, including or excluding a shift of the effective point of measurement, resulted in depth-dose differences of about +/- 0.5% or less for both applicators. The smallest depth-dose differences were obtained when a shift of the effective point of measurement was implemented, being displaced 0.4 mm towards the center of the sensitive volume of the chamber. The correction factors were obtained with combined uncertainties of 0.4% (k = 2). Uncertainties due to chamber-to-chamber differences are found to be lower than 2%. The results emphasize the relevance of carrying out detailed Monte Carlo studies for each electronic brachytherapy device and ionization chamber used for its dosimetry.
Address [Valdes-Cortez, Christian; Ballester, Facundo; Vijande, Javier] Univ Valencia UV, Dept Fis Atom Mol & Nucl, Burjassot, Spain, Email: cvalcort@gmail.com
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000618031500001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 4708
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Author Borys, D. et al; Brzezinski, K.
Title ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging Type Journal Article
Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 67 Issue (down) 22 Pages 224002 - 15pp
Keywords proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging
Abstract Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022).
Address [Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000885248200001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 5416
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Author Gimenez-Alventosa, V.; Gimenez, V.; Ballester, F.; Vijande, J.; Andreo, P.
Title Monte Carlo calculation of beam quality correction factors for PTW cylindrical ionization chambers in photon beams Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue (down) 20 Pages 205005 - 11pp
Keywords TRS 398; Monte Carlo; dosimetry; ionization chambers; MV photon beams
Abstract The beam quality correction factork(Q)for megavoltage photon beams has been calculated for eight PTW (Freiburg, Germany) ionization chambers (Farmer chambers PTW30010, PTW30011, PTW30012, and PTW30013, Semiflex 3D chambers PTW31021, PTW31010, and PTW31013, and the PinPoint 3D chamber PTW31016). Simulations performed on the widely used NE-2571 ionization chamber have been used to benchmark the results. The Monte Carlo code PENELOPE/penEasy was used to calculate the absorbed dose to a point in water and the absorbed dose to the active air volume of the chambers for photon beams in the range 4 to 24 MV. Of the nine ionization chambers analysed, only five are included in the current version of the International Code of Practice for dosimetry based on standards of absorbed dose to water (IAEA TRS 398). The values reported in this work agree with those in the literature within the uncertainty estimates and are to be included in the average values of the data obtained by different working groups for the forthcoming update of TRS 398.
Address [Gimenez-Alventosa, Vicent] Univ Politecn Valencia, CSIC, Ctr Mixto, Inst Instrumentac Imagen Mol I3M, Valencia, Spain, Email: javier.vijande@uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000576070000001 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 4556
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Author ATLAS Collaboration (Adragna, P. et al); Castelo, J.; Castillo Gimenez, V.; Cuenca, C.; Ferrer, A.; Fullana, E.; Gonzalez, V.; Higon-Rodriguez, E.; Poveda, J.; Ruiz, A.; Salvachua, B.; Sanchis, E.; Solans, C.; Torres, J.; Valero, A.; Valls Ferrer, J.A.
Title Measurement of pion and proton response and longitudinal shower profiles up to 20 nuclear interaction lengths with the ATLAS Tile calorimeter Type Journal Article
Year 2010 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 615 Issue (down) 2 Pages 158-181
Keywords Calorimeter; Test-beam; ATLAS; Monte Carlo simulation; GEANT4; Hadronic shower development; Pion-proton response; Longitudinal shower profile for hadrons
Abstract The response of pions and protons in the energy range of 20-180 GeV, produced at CERN's SPS H8 test-beam line in the ATLAS iron-scintillator Tile hadron calorimeter, has been measured. The test-beam configuration allowed the measurement of the longitudinal shower development for pions and protons up to 20 nuclear interaction lengths. It was found that pions penetrate deeper in the calorimeter than protons. However, protons induce showers that are wider laterally to the direction of the impinging particle. Including the measured total energy response, the pion-to-proton energy ratio and the resolution, all observations are consistent with a higher electromagnetic energy fraction in pion-induced showers. The data are compared with GEANT4 simulations using several hadronic physics lists. The measured longitudinal shower profiles are described by an analytical shower parametrization within an accuracy of 5-10%. The amount of energy leaking out behind the calorimeter is determined and parametrized as a function of the beam energy and the calorimeter depth. This allows for a leakage correction of test-beam results in the standard projective geometry.
Address [Hakobyan, H.; Simonyan, M.] Yerevan Phys Inst, Yerevan 375036, Armenia, Email: Margar.Simonyan@cern.ch
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes ISI:000276299900002 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 252
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Author Rivard, M.J.; Granero, D.; Perez-Calatayud, J.; Ballester, F.
Title Influence of photon energy spectra from brachytherapy sources on Monte Carlo simulations of kerma and dose rates in water and air Type Journal Article
Year 2010 Publication Medical Physics Abbreviated Journal Med. Phys.
Volume 37 Issue (down) 2 Pages 869-876
Keywords biomedical materials; brachytherapy; dosimetry; iodine; iridium; Monte Carlo methods; palladium; radioisotopes
Abstract Methods: For Ir-192, I-125, and Pd-103, the authors considered from two to five published spectra. Spherical sources approximating common brachytherapy sources were assessed. Kerma and dose results from GEANT4, MCNP5, and PENELOPE-2008 were compared for water and air. The dosimetric influence of Ir-192, I-125, and Pd-103 spectral choice was determined. Results: For the spectra considered, there were no statistically significant differences between kerma or dose results based on Monte Carlo code choice when using the same spectrum. Water-kerma differences of about 2%, 2%, and 0.7% were observed due to spectrum choice for Ir-192, I-125, and Pd-103, respectively (independent of radial distance), when accounting for photon yield per Bq. Similar differences were observed for air-kerma rate. However, their ratio (as used in the dose-rate constant) did not significantly change when the various photon spectra were selected because the differences compensated each other when dividing dose rate by air-kerma strength. Conclusions: Given the standardization of radionuclide data available from the National Nuclear Data Center (NNDC) and the rigorous infrastructure for performing and maintaining the data set evaluations, NNDC spectra are suggested for brachytherapy simulations in medical physics applications.
Address [Rivard, Mark J.] Tufts Univ, Sch Med, Dept Radiat Oncol, Boston, MA 02111 USA, Email: mrivard@tuftsmedicalcenter.org
Corporate Author Thesis
Publisher Amer Assoc Physicists Medicine Amer Inst Physics Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes ISI:000274075600048 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 504
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Author Hornillos, M.B.G.; Gorlychev, V.; Caballero, R.; Cortes, G.; Poch, A.; Pretel, C.; Calvino, F.; Tain, J.L.; Algora, A.; Agramunt, J.; Cano-Ott, D.; Martinez, T.; Mendoza, E.; Rissanen, J.; Aysto, J.; Jokinen, A.; Eronen, T.; Moore, I.; Penttila, H.
Title Monte Carlo Simulations for the Study of a Moderated Neutron Detector Type Journal Article
Year 2011 Publication Journal of the Korean Physical Society Abbreviated Journal J. Korean Phys. Soc.
Volume 59 Issue (down) 2 Pages 1573-1576
Keywords Monte Carlo simulations; GEANT4; MCNPX; Beta delayed neutron emission; Neutron detector
Abstract This work presents the Monte Carlo simulations performed with the MCNPX and GEANT4 codes for the design of a BEta deLayEd Neutron detector, BELEN-20. This detector will be used for the study of beta delayed neutron emission and consists of a block of polyethylene with dimensions 90 x 90 x 80 cm(3) and 20 cylindrical (3)He gas counters. The results of these simulations have been validated experimentally with a (252)Cf source in the laboratory at UPC, Barcelona. Also the first experiment with this detector has been carried out in November 2009 in JYFL, Finland. In this experiment the neutron emission probability after beta decay of the fission products (88)Br, (94,95)Rb, and (138)I has been measured; this data is still under analysis. Simulations with MCNPX and GEANT4 have been performed in order to obtain the efficiency of the BELEN-20 detector for each of the above nuclei using the neutron energy distribution corresponding to each nucleus.
Address [Hornillos, MBG; Gorlychev, V; Caballero, R; Cortes, G; Poch, A; Pretel, C; Calvino, F] Univ Politecn Cataluna, Seccio Engn Nucl, E-08028 Barcelona, Spain, Email: belen.gomez@upc.edu
Corporate Author Thesis
Publisher Korean Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0374-4884 ISBN Medium
Area Expedition Conference
Notes WOS:000294080700028 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 733
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Author n_TOF Collaboration (Mendoza, E. et al); Giubrone, G.; Tain, J.L.
Title Improved Neutron Capture Cross Section Measurements with the n_TOF Total Absorption Calorimeter Type Journal Article
Year 2011 Publication Journal of the Korean Physical Society Abbreviated Journal J. Korean Phys. Soc.
Volume 59 Issue (down) 2 Pages 1813-1816
Keywords ND2010; Nuclear data; n_TOF; Background; Monte Carlo; Neutron; Time of flight; Cross section; Calorimeter; Shielding; Simulation; Total absorption; Gamma ray; Neutron capture
Abstract The n_TOF collaboration operates a Total Absorption Calorimeter (TAC) [1] for measuring neutron capture cross-sections of low-mass and/or radioactive samples. The results obtained with the TAC have led to a substantial improvement of the capture cross sections of (237)Np and (240)Pu [2]. The experience acquired during the first measurements has allowed us to optimize the performance of the TAC and to improve the capture signal to background ratio, thus opening the way to more complex and demanding measurements on rare radioactive materials. The new design has been reached by a series of detailed Monte Carlo simulations of complete experiments and dedicated test measurements. The new capture setup will be presented and the main achievements highlighted.
Address [Mendoza, E; Becares, V; Casado, A; Cano-Ott, D; Fernandez-Ordonez, M; Gonzalez-Romero, E; Guerrero, C; Martinez, T; Vidriales, JJ] Ctr Invest Energet Medioambientales & Tecnol, Madrid 28040, Spain, Email: emilio.mendoza@ciemat.es
Corporate Author Thesis
Publisher Korean Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0374-4884 ISBN Medium
Area Expedition Conference
Notes WOS:000294080700086 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 738
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