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Author Garonna, A.; Amaldi, U.; Bonomi, R.; Campo, D.; Degiovanni, A.; Garlasche, M.; Mondino, I.; Rizzoglio, V.; Verdu-Andres, S.
Title Cyclinac medical accelerators using pulsed C6+/H-2(+) ion sources Type Journal Article
Year 2010 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 5 Issue (up) Pages C09004 - 19pp
Keywords Instrumentation for particle-beam therapy; Instrumentation for hadron therapy; Ion sources (positive ions, negative ions, electron cyclotron resonance (ECR), electron beam (EBIS)); Acceleration cavities and magnets superconducting (high-temperature superconductor; radiation hardened magnets; normal-conducting; permanent magnet devices; wigglers and undulators)
Abstract Charged particle therapy, or so-called hadrontherapy, is developing very rapidly. There is large pressure on the scientific community to deliver dedicated accelerators, providing the best possible treatment modalities at the lowest cost. In this context, the Italian research Foundation TERA is developing fast-cycling accelerators, dubbed 'cyclinacs'. These are a combination of a cyclotron (accelerating ions to a fixed initial energy) followed by a high gradient linac boosting the ions energy up to the maximum needed for medical therapy. The linac is powered by many independently controlled klystrons to vary the beam energy from one pulse to the next. This accelerator is best suited to treat moving organs with a 4D multipainting spot scanning technique. A dual proton/carbon ion cyclinac is here presented. It consists of an Electron Beam Ion Source, a superconducting isochronous cyclotron and a high-gradient linac. All these machines are pulsed at high repetition rate (100-400 Hz). The source should deliver both C6+ and H-2(+) ions in short pulses (1.5 μs flat-top) and with sufficient intensity (at least 10(8) fully stripped carbon ions per pulse at 300 Hz). The cyclotron accelerates the ions to 120 MeV/u. It features a compact design (with superconducting coils) and a low power consumption. The linac has a novel C-band high-gradient structure and accelerates the ions to variable energies up to 400 MeV/u. High RF frequencies lead to power consumptions which are much lower than the ones of synchrotrons for the same ion extraction energy. This work is part of a collaboration with the CLIC group, which is working at CERN on high-gradient electron-positron colliders.
Address [Garonna, A.; Amaldi, U.; Bonomi, R.; Campo, D.; Degiovanni, A.; Garlasche, M.; Mondino, I.; Rizzoglio, V.; Andres, S. Verdu] TERA Fdn, I-28100 Novara, Italy, Email: Adriano.Garonna@cern.ch
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes ISI:000283796100011 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 327
Permanent link to this record
 
 
Author ATLAS Collaboration (Abat, E. et al); Bernabeu Verdu, J.; Castillo Gimenez, V.; Costa, M.J.; Escobar, C.; Ferrer, A.; Garcia, C.; Gonzalez-Sevilla, S.; Higon-Rodriguez, E.; Lacasta, C.; Marti-Garcia, S.; Mitsou, V.A.; Ruiz, A.; Solans, C.; Valero, A.; Valls Ferrer, J.A.
Title A layer correlation technique for pion energy calibration at the 2004 ATLAS Combined Beam Test Type Journal Article
Year 2011 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 6 Issue (up) Pages P06001 - 35pp
Keywords Calorimeter methods; Pattern recognition, cluster finding, calibration and fitting methods; Calorimeters; Detector modelling and simulations I (interaction of radiation with matter, interaction of photons with matter, interaction of hadrons with matter, etc)
Abstract A new method for calibrating the hadron response of a segmented calorimeter is developed and successfully applied to beam test data. It is based on a principal component analysis of energy deposits in the calorimeter layers, exploiting longitudinal shower development information to improve the measured energy resolution. Corrections for invisible hadronic energy and energy lost in dead material in front of and between the calorimeters of the ATLAS experiment were calculated with simulated Geant4 Monte Carlo events and used to reconstruct the energy of pions impinging on the calorimeters during the 2004 Barrel Combined Beam Test at the CERN H8 area. For pion beams with energies between 20 GeV and 180 GeV, the particle energy is reconstructed within 3% and the energy resolution is improved by between 11% and 25% compared to the resolution at the electromagnetic scale.
Address [Wheeler, S] Univ Alberta, Dept Phys, Ctr Particle Phys, Edmonton, AB T6G 2G7, Canada[Bernabeu, J; Castillo, MV; Costa, MJ; Escobar, C; Ferrer, A; Garcia, C; Gonzalez-Sevilla, S; Higon, E; Lacasta, C; Garcia, SMI; Mitsou, VA; Ruiz, A; Solans, C; Valero, A; Valls, JA] Ctr Mixto UVEG CSIC, Inst Fis Corpuscular IFIC, ES-46071 Valencia, Spain, Email: kjg@particle.kth.se
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000294492600001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ elepoucu @ Serial 744
Permanent link to this record
 
 
Author Llosa, G.; Barrio, J.; Cabello, J.; Crespo, A.; Lacasta, C.; Rafecas, M.; Callier, S.; de la Taille, C.; Raux, L.
Title Detector characterization and first coincidence tests of a Compton telescope based on LaBr3 crystals and SiPMs Type Journal Article
Year 2012 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 695 Issue (up) Pages 105-108
Keywords Hadron therapy; Compton imaging; LaBr3; Continuous crystal; SiPM; MPPC; G-APD
Abstract A Compton telescope for dose monitoring in hadron therapy consisting of several layers of continuous LaBr3 crystals coupled to silicon photomultiplier (SiPM) arrays is under development within the ENVISION project. In order to test the possibility of employing such detectors for the telescope, a detector head consisting of a continuous 16 mm x 18 mm x 5 mm LaBr3 crystal coupled to a SiPM array has been assembled and characterized, employing the SPIROC1 ASIC as readout electronics. The best energy resolution obtained at 511 key is 6.5% FWHM and the timing resolution is 3.1 ns FWHM. A position determination method for continuous crystals is being tested, with promising results. In addition, the detector has been operated in time coincidence with a second detector layer, to determine the coincidence capabilities of the system. The first tests are satisfactory, and encourage the development of larger detectors that will compose the telescope prototype.
Address [Llosa, G.; Barrio, J.; Cabello, J.; Crespo, A.; Lacasta, C.; Rafecas, M.] UVEG, CSIC, IFIC, Inst Fis Corpuscular, Valencia, Spain, Email: gabriela.llosa@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000311469900020 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1235
Permanent link to this record
 
 
Author ATLAS Collaboration (Aad, G. et al); Amoros, G.; Cabrera Urban, S.; Castillo Gimenez, V.; Costa, M.J.; Ferrer, A.; Fiorini, L.; Fuster, J.; Garcia, C.; Gonzalez de la Hoz, S.; Hernandez Jimenez, Y.; Higon-Rodriguez, E.; Irles Quiles, A.; Kaci, M.; Lacasta, C.; Lacuesta, V.R.; Marti-Garcia, S.; Miñano, M.; Mitsou, V.A.; Moles-Valls, R.; Moreno Llacer, M.; Oliver Garcia, E.; Perez Garcia-Estañ, M.T.; Ros, E.; Salt, J.; Solans, C.A.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valladolid Gallego, E.; Valls Ferrer, J.A.; Villaplana Perez, M.; Vos, M.; Wildauer, A.
Title A study of the material in the ATLAS inner detector using secondary hadronic interactions Type Journal Article
Year 2012 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 7 Issue (up) Pages P01013 - 40pp
Keywords Detector modelling and simulations I (interaction of radiation with matter, interaction; of photons with matter, interaction of hadrons with matter, etc); Particle tracking detectors (Solid-state detectors); Si microstrip and pad detectors; Large detector systems for particle and astroparticle physics
Abstract The ATLAS inner detector is used to reconstruct secondary vertices due to hadronic interactions of primary collision products, so probing the location and amount of material in the inner region of ATLAS. Data collected in 7 TeV pp collisions at the LHC, with a minimum bias trigger, are used for comparisons with simulated events. The reconstructed secondary vertices have spatial resolutions ranging from similar to 200 μm to 1 mm. The overall material description in the simulation is validated to within an experimental uncertainty of about 7%. This will lead to a better understanding of the reconstruction of various objects such as tracks, leptons, jets, and missing transverse momentum.
Address [Aad, G.; Ahles, F.; Bernhard, R.; Bitenc, U.; Bruneliere, R.; Caron, S.; Christov, A.; Consorti, V.; Eckert, S.; Fehling-Kaschek, M.; Flechl, M.; Glatzer, J.; Hartert, J.; Herten, G.; Horner, S.; Jakobs, K.; Ketterer, C.; Kollefrath, M.; Kononov, A. I.; Kuehn, S.; Lai, S.; Landgraf, U.; Lohwasser, K.; Ludwig, I.; Ludwig, J.; Lumb, D.; Mahboubi, K.; Meinhardt, J.; Mohr, W.; Nilsen, H.; Parzefall, U.; Rammensee, M.; Runge, K.; Rurikova, Z.; Schmidt, E.; Schumacher, M.; Siegert, F.; Stoerig, K.; Sundermann, J. E.; Temming, K. K.; Thoma, S.; Tobias, J.; Tsiskaridze, V.; Venturi, M.; Vivarelli, I.; von Radziewski, H.; Warsinsky, M.; Weiser, C.; Werner, M.; Wiik, L. A. M.; Winkelmann, S.; Xie, S.; Zimmermann, S.] Univ Freiburg, Fak Math & Phys, D-79106 Freiburg, Germany
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000303806200127 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1040
Permanent link to this record
 
 
Author Llosa, G.; Barrio, J.; Lacasta, C.; Callier, S.; Raux, L.; de La Taille, C.
Title First tests in the application of silicon photomultiplier arrays to dose monitoring in hadron therapy Type Journal Article
Year 2011 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 648 Issue (up) Pages S96-S99
Keywords Hadron therapy; Compton imaging; LaBr3; Continuous crystal; SiPM; MPPC; G-APD
Abstract A detector head composed of a continuous LaBr3 crystal coupled to a silicon photomultiplier array has been mounted and tested, for its use in a Compton telescope for dose monitoring in hadron therapy. The LaBr3 crystal has 16 mm x 18 mm x 5 mm size, and it is surrounded with reflecting material in five faces. The SiPM array has 16 (4 x 4) elements of 3 mm x 3 mm size. The SPIROC1 ASIC has been employed as readout electronics. The detector shows a linear behavior up to 1275 keV. The energy resolution obtained at 511 keV is 7% FWHM, and it varies as one over the square root of the energy up to the energies tested. The variations among the detector channels are within 12%. A preliminary measurement of the timing resolution gives 7 ns FWHM. The spatial resolution obtained with the center of gravity method is 1.2 mm FWHM. The tests performed confirm the correct functioning of the detector.
Address [Llosa, G.; Barrio, J.; Lacasta, C.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: gabriela.llosa@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000305376900026 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1068
Permanent link to this record
 
 
Author Verdu-Andres, S.; Amaldi, U.; Faus-Golfe, A.
Title CABOTO, a high-gradient linac for hadrontherapy Type Journal Article
Year 2013 Publication Journal of Radiation Research Abbreviated Journal J. Radiat. Res.
Volume 54 Issue (up) Pages 155-161
Keywords hadrontherapy; high-gradient linac; cyclinac; carbon ion therapy; multipainting
Abstract The field of hadrontherapy has grown rapidly in recent years. At present the therapeutic beam is provided by a cyclotron or a synchrotron, but neither cyclotrons nor synchrotrons present the best performances for hadrontherapy. The new generation of accelerators for hadrontherapy should allow fast active energy modulation and have a high repetition rate, so that moving organs can be appropriately treated in a reasonable time. In addition, a reduction of the dimensions and cost of the accelerators for hadrontherapy would make the acquisition and operation of a hadrontherapy facility more affordable, which would translate into great benefits for the potential hadrontherapy patients. The 'cyclinac', an accelerator concept that combines a cyclotron with a high-frequency linear accelerator (linac), is a fast-cycling machine specifically conceived to allow for fast active energy modulation. The present paper focuses on CABOTO (CArbon BOoster for Therapy in Oncology), a compact, efficient high-frequency linac that can accelerate C6+ ions and H-2 molecules from 150-410 MeV/u in similar to 24 m. The paper presents the latest design of CABOTO and discusses its performances.
Address [Verdu-Andres, Silvia; Amaldi, Ugo] Fdn Tera, I-28100 Novara, Italy, Email: sverdu@bnl.gov
Corporate Author Thesis
Publisher Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3060 ISBN Medium
Area Expedition Conference
Notes WOS:000321463900021 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1506
Permanent link to this record
 
 
Author Roman, F.L.; Abler, D.; Kanellopoulos, V.; Amoros, G.; Davies, J.; Dosanjh, M.; Jena, R.; Kirkby, N.; Peach, K.; Salt, J.
Title Hadron therapy information sharing prototype Type Journal Article
Year 2013 Publication Journal of Radiation Research Abbreviated Journal J. Radiat. Res.
Volume 54 Issue (up) Pages 56-60
Keywords hadron therapy; proton therapy; data federation; web portal; eHealth; cancer informatics
Abstract The European PARTNER project developed a prototypical system for sharing hadron therapy data. This system allows doctors and patients to record and report treatment-related events during and after hadron therapy. It presents doctors and statisticians with an integrated view of adverse events across institutions, using open-source components for data federation, semantics, and analysis. There is a particular emphasis upon semantic consistency, achieved through intelligent, annotated form designs. The system as presented is ready for use in a clinical setting, and amenable to further customization. The essential contribution of the work reported here lies in the novel data integration and reporting methods, as well as the approach to software sustainability achieved through the use of community-supported open-source components.
Address [Roman, Faustin Laurentiu; Abler, Daniel; Kanellopoulos, Vassiliki; Dosanjh, Manjit] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland, Email: faustin.roman@medaustron.at
Corporate Author Thesis
Publisher Oxford Univ Press Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0449-3060 ISBN Medium
Area Expedition Conference
Notes WOS:000321463900008 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1519
Permanent link to this record
 
 
Author Vijande, J.; Valcarce, A.; Carames, T.F.; Garcilazo, H.
Title Heavy hadron spectroscopy: A quark model perspective Type Journal Article
Year 2013 Publication Nuclear Physics A Abbreviated Journal Nucl. Phys. A
Volume 914 Issue (up) Pages 472-481
Keywords Heavy hadrons; Constituent quark model; Many-quark systems
Abstract We present recent results of hadron spectroscopy and hadron-hadron interaction from the perspective of constituent quark models. We pay special attention to the role played by higher order Fock space components in the hadron spectra and the connection of this extension with the hadron-hadron interaction. The main goal of our description is to obtain a coherent understanding of the low-energy hadron phenomenology without enforcing any particular model, to constrain its characteristics and learn about low-energy realization of the theory.
Address [Vijande, J.] UV, Dept Fis Atom Mol & Nucl, Valencia, Spain, Email: javier.vijande@uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0375-9474 ISBN Medium
Area Expedition Conference
Notes WOS:000324847700067 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1599
Permanent link to this record
 
 
Author Alvarez-Ruso, L.; Hayato, Y.; Nieves, J.
Title Progress and open questions in the physics of neutrino cross sections at intermediate energies Type Journal Article
Year 2014 Publication New Journal of Physics Abbreviated Journal New J. Phys.
Volume 16 Issue (up) Pages 075015 - 62pp
Keywords neutrino cross sections; oscillation experiments; electroweak hadronic form factors; nuclear effects
Abstract New and more precise measurements of neutrino cross sections have renewed interest in a better understanding of electroweak interactions on nucleons and nuclei. This effort is crucial to achieving the precision goals of the neutrino oscillation program, making new discoveries, like the CP violation in the leptonic sector, possible. We review the recent progress in the physics of neutrino cross sections, putting emphasis on the open questions that arise in the comparison with new experimental data. Following an overview of recent neutrino experiments and future plans, we present some details about the theoretical development in the description of (anti) neutrino-induced quasielastic (QE) scattering and the role of multi-nucleon QE-like mechanisms. We cover not only pion production in nucleons and nuclei but also other inelastic channels including strangeness production and photon emission. Coherent reaction channels on nuclear targets are also discussed. Finally, we briefly describe some of the Monte Carlo event generators, which are at the core of all neutrino oscillation and cross-section measurements.
Address [Alvarez-Ruso, L.; Nieves, J.] Univ Valencia, Ctr Mixto CSIC, Inst Fis Corpuscular IFIC, E-46071 Valencia, Spain, Email: luis.alvarez@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1367-2630 ISBN Medium
Area Expedition Conference
Notes WOS:000341829000001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1927
Permanent link to this record
 
 
Author ATLAS Collaboration (Aad, G. et al); Bernabeu Verdu, J.; Cabrera Urban, S.; Castillo Gimenez, V.; Costa, M.J.; Fassi, F.; Ferrer, A.; Fiorini, L.; Fuster, J.; Garcia, C.; Garcia-Argos, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Hernandez Jimenez, Y.; Higon-Rodriguez, E.; Irles Quiles, A.; Kaci, M.; King, M.; Lacasta, C.; Lacuesta, V.R.; March, L.; Marti-Garcia, S.; Miñano, M.; Mitsou, V.A.; Moles-Valls, R.; Oliver Garcia, E.; Pedraza Lopez, S.; Perez Garcia-Estañ, M.T.; Romero Adam, E.; Ros, E.; Salt, J.; Sanchez Martinez, V.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valladolid Gallego, E.; Valls Ferrer, J.A.; Villaplana Perez, M.; Vos, M.
Title Operation and performance of the ATLAS semiconductor tracker Type Journal Article
Year 2014 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.
Volume 9 Issue (up) Pages P08009 - 73pp
Keywords Solid state detectors; Charge transport and multiplication in solid media; Particle tracking detectors (Solid-state detectors); Detector modelling and simulations I (interaction of radiation with matter, interaction of photons with matter, interaction of hadrons with matter, etc)
Abstract The semiconductor tracker is a silicon microstrip detector forming part of the inner tracking system of the ATLAS experiment at the LHC. The operation and performance of the semiconductor tracker during the first years of LHC running are described. More than 99% of the detector modules were operational during this period, with an average intrinsic hit efficiency of (99.74 +/- 0.04)%. The evolution of the noise occupancy is discussed, and measurements of the Lorentz angle, delta-ray production and energy loss presented. The alignment of the detector is found to be stable at the few-micron level over long periods of time. Radiation damage measurements, which include the evolution of detector leakage currents, are found to be consistent with predictions and are used in the verification of radiation background simulations.
Address [Jackson, P.; Soni, N.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1748-0221 ISBN Medium
Area Expedition Conference
Notes WOS:000341927600037 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 1945
Permanent link to this record