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Author |
Candela-Juan, C.; Vijande, J.; Garcia-Martinez, T.; Niatsetski, Y.; Nauta, G.; Schuurman, J.; Ouhib, Z.; Ballester, F.; Perez-Calatayud, J. |
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Title |
Comparison and uncertainty evaluation of different calibration protocols and ionization chambers for low-energy surface brachytherapy dosimetry |
Type |
Journal Article |
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Year |
2015 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
42 |
Issue |
8 |
Pages |
4954-4964 |
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Keywords |
x-ray beams; electronic brachytherapy; surface applicators; dosimetry; uncertainty |
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Abstract |
Purpose: A surface electronic brachytherapy (EBT) device is in fact an x-ray source collimated with specific applicators. Low-energy (<100 kVp) x-ray beam dosimetry faces several challenges that need to be addressed. A number of calibration protocols have been published for x-ray beam dosimetry. The media in which measurements are performed are the fundamental difference between them. The aim of this study was to evaluate the surface dose rate of a low-energy x-ray source with small field applicators using different calibration standards and different small-volume ionization chambers, comparing the values and uncertainties of each methodology. Methods: The surface dose rate of the EBT unit Esteya (Elekta Brachytherapy, The Netherlands), a 69.5 kVp x-ray source with applicators of 10, 15, 20, 25, and 30 mm diameter, was evaluated using the AAPM TG-61 (based on air kerma) and International Atomic Energy Agency (IAEA) TRS-398 (based on absorbed dose to water) dosimetry protocols for low-energy photon beams. A plane parallel T34013 ionization chamber (PTW Freiburg, Germany) calibrated in terms of both absorbed dose to water and air kerma was used to compare the two dosimetry protocols. Another PTW chamber of the same model was used to evaluate the reproducibility between these chambers. Measurements were also performed with two different Exradin A20 (Standard Imaging, Inc., Middleton, WI) chambers calibrated in terms of air kerma. Results: Differences between surface dose rates measured in air and in water using the T34013 chamber range from 1.6% to 3.3%. No field size dependence has been observed. Differences are below 3.7% when measurements with the A20 and the T34013 chambers calibrated in air are compared. Estimated uncertainty (with coverage factor k = 1) for the T34013 chamber calibrated in water is 2.2%-2.4%, whereas it increases to 2.5% and 2.7% for the A20 and T34013 chambers calibrated in air, respectively. The output factors, measured with the PTW chambers, differ by less than 1.1% for any applicator size when compared to the output factors that were measured with the A20 chamber. Conclusions: Measurements using both dosimetric protocols are consistent, once the overall uncertainties are considered. There is also consistency between measurements performed with both chambers calibrated in air. Both the T34013 and A20 chambers have negligible stem effect. Any x-ray surface brachytherapy system, including Esteya, can be characterized using either one of these calibration protocols and ionization chambers. Having less correction factors, lower uncertainty, and based on measurements, performed in closer to clinical conditions, the TRS-398 protocol seems to be the preferred option. |
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Address |
[Candela-Juan, C.; Perez-Calatayud, J.] La Fe Univ, Dept Radiat Oncol, Valencia 46026, Spain, Email: ccanjuan@gmail.com |
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Amer Assoc Physicists Medicine Amer Inst Physics |
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0094-2405 |
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WOS:000358933000051 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
2323 |
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Author |
Valdes-Cortez, C.; Niatsetski, Y.; Perez-Calatayud, J.; Ballester, F.; Vijande, J. |
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Title |
A Monte Carlo study of the relative biological effectiveness in surface brachytherapy |
Type |
Journal Article |
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Year |
2022 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
49 |
Issue |
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Pages |
5576-5588 |
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Keywords |
Monte Carlo; relative biological effectiveness; surface HDR brachytherapy |
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Abstract |
Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value. |
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[Valdes-Cortez, Christian] Hosp Reg Antofagasta, Nucl Med Dept, Antofagasta, Chile, Email: cvalcort@gmail.com |
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Wiley |
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English |
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0094-2405 |
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Notes |
WOS:000811709400001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5262 |
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Author |
Assam, I.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Poppe, B.; Siebert, F.A. |
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Title |
Evaluation of dosimetric effects of metallic artifact reduction and tissue assignment on Monte Carlo dose calculations for I-125 prostate implants |
Type |
Journal Article |
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Year |
2022 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
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Volume |
49 |
Issue |
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Pages |
6195-6208 |
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Keywords |
metallic artifact reduction; Monte Carlo dosimetry; post-implant CT; prostate brachytherapy; tissue assignment schemes; voxelized virtual patient model |
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Abstract |
Purpose Monte Carlo (MC) simulation studies, aimed at evaluating the magnitude of tissue heterogeneity in I-125 prostate permanent seed implant brachytherapy (BT), customarily use clinical post-implant CT images to generate a virtual representation of a realistic patient model (virtual patient model). Metallic artifact reduction (MAR) techniques and tissue assignment schemes (TAS) are implemented on the post-implant CT images to mollify metallic artifacts due to BT seeds and to assign tissue types to the voxels corresponding to the bright seed spots and streaking artifacts, respectively. The objective of this study is to assess the combined influence of MAR and TAS on MC absorbed dose calculations in post-implant CT-based phantoms. The virtual patient models used for I-125 prostate implant MC absorbed dose calculations in this study are derived from the CT images of an external radiotherapy prostate patient without BT seeds and prostatic calcifications, thus averting the need to implement MAR and TAS. Methods The geometry of the IsoSeed I25.S17plus source is validated by comparing the MC calculated results of the TG-43 parameters for the line source approximation with the TG-43U1S2 consensus data. Four MC absorbed dose calculations are performed in two virtual patient models using the egs_brachy MC code: (1) TG-43-based D-w,w-TG(43), (2) D-w,D-w-MBDC that accounts for interseed scattering and attenuation (ISA), (3) D-m,D-m that examines ISA and tissue heterogeneity by scoring absorbed dose in tissue, and (4) D-w,D-m that unlike D-m,D-m scores absorbed dose in water. The MC absorbed doses (1) and (2) are simulated in a TG-43 patient phantom derived by assigning the densities of every voxel to 1.00 g cm(-3) (water), whereas MC absorbed doses (3) and (4) are scored in the TG-186 patient phantom generated by mapping the mass density of each voxel to tissue according to a CT calibration curve. The MC absorbed doses calculated in this study are compared with VariSeed v8.0 calculated absorbed doses. To evaluate the dosimetric effect of MAR and TAS, the MC absorbed doses of this work (independent of MAR and TAS) are compared to the MC absorbed doses of different I-125 source models from previous studies that were calculated with different MC codes using post-implant CT-based phantoms generated by implementing MAR and TAS on post-implant CT images. Results The very good agreement of TG-43 parameters of this study and the published consensus data within 3% validates the geometry of the IsoSeed I25.S17plus source. For the clinical studies, the TG-43-based calculations show a D-90 overestimation of more than 4% compared to the more realistic MC methods due to ISA and tissue composition. The results of this work generally show few discrepancies with the post-implant CT-based dosimetry studies with respect to the D-90 absorbed dose metric parameter. These discrepancies are mainly Type B uncertainties due to the different I-125 source models and MC codes. Conclusions The implementation of MAR and TAS on post-implant CT images have no dosimetric effect on the I-125 prostate MC absorbed dose calculation in post-implant CT-based phantoms. |
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Address |
[Assam, Isong; Siebert, Frank-Andre] UKSH, Clin Radiotherapy Radiooncol, Campus Kiel, Kiel, Germany, Email: Isong.Assam@uksh.de |
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Wiley |
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English |
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0094-2405 |
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Notes |
WOS:000835807200001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5321 |
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Permanent link to this record |
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Author |
Garcia Canal, C.A.; Tarutina, T.; Vento, V. |
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Title |
Analysis of Nuclear Effects in Structure Functions and Their Connection with the Binding Energy of Nuclei |
Type |
Journal Article |
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Year |
2023 |
Publication |
Brazilian Journal of Physics |
Abbreviated Journal |
Braz. J. Phys. |
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Volume |
53 |
Issue |
6 |
Pages |
161 - 8pp |
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Keywords |
Structure functions; Deep inelastic scattering; EMC effect; Nuclear dynamics |
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Abstract |
We describe nuclear effects in structure functions of nuclei in DIS by means of a multiplicative factor beta(A)(x) which differentiates the structure function of the bound nucleons from that of the free nucleons. Our analysis determines that beta(A)(x) establishes a relation between the quark-gluon dynamics expressed by the bound nucleon structure functions and the nuclear dynamics as described by the well-known semi-empirical Bethe-Weizsacker mass formula. This relation corroborates a connection between the underlying quark-gluon dynamics and the phenomenological nuclear dynamics. |
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[Canal, C. A. Garcia] Univ La Plata, Dept Phys, Cc 67, RA-1900 La Plata, Argentina, Email: ttarutina@gmail.com |
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Springer |
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English |
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ISSN |
0103-9733 |
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Notes |
WOS:001087936700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5766 |
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Permanent link to this record |
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Author |
Fujita, Y.; Rubio, B.; Gelletly, W. |
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Title |
Spin-isospin excitations probed by strong, weak and electro-magnetic interactions |
Type |
Journal Article |
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Year |
2011 |
Publication |
Progress in Particle and Nuclear Physics |
Abbreviated Journal |
Prog. Part. Nucl. Phys. |
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Volume |
66 |
Issue |
3 |
Pages |
549-606 |
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Keywords |
Gamow-Teller transitions; beta decay; Charge-exchange reactions; Isospin symmetry; High resolution; Proton-rich nuclei |
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Abstract |
Gamow-Teller (GT) transitions are the most common weak interaction processes of spin-isospin (sigma tau) type in atomic nuclei. They are of interest not only in nuclear physics but also in astrophysics; they play an important role in supernovae explosions and nucleosynthesis. The direct study of weak decay processes, however, gives relatively limited information about GT transitions and the states excited via GT transitions (GT states); beta decay can only access states at excitation energies lower than the decay Q-value, and neutrino-induced reactions have very small cross-sections. However, one should note that beta decay has a direct access to the absolute GT transition strengths B(GT) from a study of half-lives, Q(beta)-values and branching ratios. They also provide information on GT transitions in nuclei far-from-stability. Studies of M1 gamma transitions provide similar information. In contrast, the complementary charge-exchange (CE) reactions, such as the (p, n) or ((3)He, t) reactions at intermediate beam energies and 0 degrees, can selectively excite GT states up to high excitation energies in the final nucleus. It has been found empirically that there is a close proportionality between the cross-sections at 0 degrees and the transition strengths B(GT) in these CE reactions. Therefore, CE reactions are useful tools to study the relative values of B(GT) strengths up to high excitation energies. In recent ((3)He, t) measurements, one order-of-magnitude improvement in the energy resolution has been achieved. This has made it possible to make one-to-one comparisons of GT transitions studied in CE reactions and beta decays. Thus GT strengths in ((3)He, t) reactions can be normalised by the beta-decay values. In addition, comparisons with closely related M1 transitions studied in gamma decay or electron inelastic scattering [(e, e')1, and furthermore with “spin” M I transitions that can be studied by proton inelastic scattering [(p, p')[ have now been made possible. In these comparisons, the isospin quantum number T and associated symmetry structure in the same mass A nuclei (isobars) play a key role. Isospin symmetry can extend our scope even to the structures of unstable nuclei that are far from reach at present unstable beam factories. |
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Address |
[Fujita, Y] Osaka Univ, Dept Phys, Osaka 5600043, Japan, Email: fujita@rcnp.osaka-u.ac.jp |
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Elsevier Science Bv |
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ISSN |
0146-6410 |
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Notes |
WOS:000292473100003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
692 |
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Permanent link to this record |
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Author |
Pich, A. |
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Title |
Precision tau physics |
Type |
Journal Article |
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Year |
2014 |
Publication |
Progress in Particle and Nuclear Physics |
Abbreviated Journal |
Prog. Part. Nucl. Phys. |
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Volume |
75 |
Issue |
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Pages |
41-85 |
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Keywords |
Electroweak and strong interactions; Leptons; Standard Model |
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Abstract |
Precise measurements of the lepton properties provide stringent tests of the Standard Model and accurate determinations of its parameters. We overview the present status of tau physics, highlighting the most recent developments, and discuss the prospects for future improvements. The leptonic decays of the tau lepton probe the structure of the weak currents and the universality of their couplings to the W boson. The universality of the leptonic Z couplings has also been tested through Z -> l(+)l(-) decays. The hadronic tau decay modes constitute an ideal tool for studying low-energy effects of the strong interaction in very clean conditions. Accurate determinations of the QCD coupling and the Cabibbo mixing V-us have been obtained with tau data. The large mass of the tau opens the possibility to study many kinematically-allowed exclusive decay modes and extract relevant dynamical information. Violations of flavour and CP conservation laws can also be searched for with tau decays. Related subjects such as μdecays, the electron and muon anomalous magnetic moments, neutrino mixing and B-meson decays into tau leptons are briefly covered. Being one the fermions most strongly coupled to the scalar sector, the tau lepton is playing now a very important role at the LHC as a tool to test the Higgs properties and search for new physics at higher scales. |
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Address |
Univ Valencia, CSIC, Dept Fis Teor, IFIC, E-46071 Valencia, Spain, Email: pich@ific.uv.es |
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Elsevier Science Bv |
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English |
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ISSN |
0146-6410 |
ISBN |
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Conference |
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Notes |
WOS:000332350600002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
1716 |
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Permanent link to this record |
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Author |
Davesne, D.; Pastore, A.; Navarro, J. |
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Title |
Linear response theory with finite-range interactions |
Type |
Journal Article |
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Year |
2021 |
Publication |
Progress in Particle and Nuclear Physics |
Abbreviated Journal |
Prog. Part. Nucl. Phys. |
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Volume |
120 |
Issue |
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Pages |
103870 - 55pp |
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Keywords |
Linear response theory; Finite-range interactions; Gogny and Nakada interactions; Finite size instabilities; Continued fraction approximation; Multipolar expansion |
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Abstract |
This review focuses on the calculation of infinite nuclear matter response functions using phenomenological finite-range interactions, equipped or not with tensor terms. These include Gogny and Nakada families, which are commonly used in the literature. Because of the finite-range, the main technical difficulty stems from the exchange terms of the particle-hole interaction. We first present results based on the so-called Landau and Landau-like approximations of the particle-hole interaction. Then, we review two methods which in principle provide numerically exact response functions. The first one is based on a multipolar expansion of both the particle-hole interaction and the particle-hole propagator and the second one consists in a continued fraction expansion of the response function. The numerical precision can be pushed to any degree of accuracy, but it is actually shown that two or three terms suffice to get converged results. Finally, we apply the formalism to the determination of possible finite-size instabilities induced by a finite-range interaction. |
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[Davesne, D.] Univ Lyon, F-69003 Lyon, France, Email: alessandro.pastore@york.ac.uk |
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Elsevier |
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English |
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ISSN |
0146-6410 |
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Notes |
WOS:000674530100008 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4910 |
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Permanent link to this record |
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Author |
Albaladejo, M.; Bibrzycki, L.; Dawid, S.M.; Fernandez-Ramirez, C.; Gonzalez-Solis, S.; Hiller Blin, A.N.; Jackura, A.W.; Mathieu, V.; Mikhasenko, M.; Make, V.I.; Passemar, E.; Pilloni, A.; Rodas, A.; Silva-Castro, J.A.; Smith, W.A.; Szczepaniak, A.P.; Winney, D. |
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Title |
Novel approaches in hadron spectroscopy |
Type |
Journal Article |
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Year |
2022 |
Publication |
Progress in Particle and Nuclear Physics |
Abbreviated Journal |
Prog. Part. Nucl. Phys. |
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Volume |
127 |
Issue |
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Pages |
103981 - 75pp |
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Keywords |
Hadron spectroscopy; Exotic hadrons; Three-body scattering; Resonance production |
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Abstract |
The last two decades have witnessed the discovery of a myriad of new and unexpected hadrons. The future holds more surprises for us, thanks to new-generation experiments. Understanding the signals and determining the properties of the states requires a parallel theoretical effort. To make full use of available and forthcoming data, a careful amplitude modeling is required, together with a sound treatment of the statistical uncertainties, and a systematic survey of the model dependencies. We review the contributions made by the Joint Physics Analysis Center to the field of hadron spectroscopy. |
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Address |
[Albaladejo, Miguel; Blin, Astrid N. Hiller; Jackura, Andrew W.; Mokeev, Victor, I; Passemar, Emilie; Rodas, Arkaitz; Szczepaniak, Adam P.] Thomas Jefferson Natl Accelerator Facil, Theory Ctr & Phys Div, Newport News, VA 23606 USA, Email: alessandro.pilloni@unime.it |
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Elsevier |
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0146-6410 |
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Notes |
WOS:000883770300003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5422 |
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Permanent link to this record |
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Author |
Bernabeu, J.; Martinez-Vidal, F. |
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Title |
Time-Reversal Violation |
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Year |
2015 |
Publication |
Annual Review of Nuclear and Particle Science |
Abbreviated Journal |
Annu. Rev. Nucl. Part. Sci. |
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Volume |
65 |
Issue |
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Pages |
403-427 |
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Keywords |
time reversal; CP violation; T-odd products; electric dipole moments; B mesons; K mesons; EPR entanglement |
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Abstract |
The violation of CP symmetry between matter and antimatter in the neutral K and B meson systems is well established, with a high degree of consistency between all available experimental measurements and with the Standard Model of particle physics. On the basis of the up-to-now-unbroken CPT symmetry, the violation of CP symmetry strongly suggests that the behavior of these particles under weak interactions must also be asymmetric under time reversal T. Many searches for T violation have been performed and proposed using different observables and experimental approaches. These include T-odd observables, such as triple products in weak decays, and genuine observables, such as permanent electric dipole moments of nondegenerate stationary states and the breaking of the reciprocity relation. We discuss the conceptual basis of the required exchange of initial and final states with unstable particles, using quantum entanglement and the decay as a filtering measurement, for the case of neutral B and K mesons. Using this method, the BaBar experiment at SLAC has clearly observed T violation in B mesons. |
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Address |
[Bernabeu, Jose; Martinez-Vidal, Fernando] Univ Valencia, CSIC, IFIC, E-46071 Valencia, Spain |
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Annual Reviews |
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0163-8998 |
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Notes |
WOS:000363473100017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2430 |
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Permanent link to this record |
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Author |
Scandale, W et al; Lari, L. |
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Title |
Deflection of high energy protons by multiple volume reflections in a modified multi-strip silicon deflector |
Type |
Journal Article |
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Year |
2014 |
Publication |
Nuclear Instruments & Methods in Physics Research B |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. B |
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Volume |
338 |
Issue |
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Pages |
108-111 |
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Keywords |
Accelerator; Beam collimation; Crystal; Channeling; Volume reflection |
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Abstract |
The effect of multiple volume reflections in one crystal was observed in each of several bent silicon strips for 400 GeV/c protons. This considerably increased the particle deflections. Some particles were also deflected due to channeling in one of the subsequent strips. As a result, the incident beam was strongly spread because of opposite directions of the deflections. A modified multi-strip deflector produced by periodic grooves on the surface of a thick silicon plate was used for these measurements. This technique provides perfect mutual alignment between crystal strips. Such multi-strip deflector may be effective for collider beam halo collimation and a study is planned at the CERN SPS circulating beam. |
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Address |
[Scandale, W.; Arduini, G.; Butcher, M.; Cerutti, F.; Gilardoni, S.; Lari, L.; Lechner, A.; Losito, R.; Masi, A.; Mereghetti, A.; Metral, E.; Mirarchi, D.; Montesano, S.; Redaelli, S.; Schoofs, P.; Smirnov, G.] CERN, European Org Nucl Res, CH-1211 Geneva 23, Switzerland |
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Thesis |
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Publisher |
Elsevier Science Bv |
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Language |
English |
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Original Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-583x |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000343390400016 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1974 |
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Permanent link to this record |