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Author |
Muñoz, E.; Ros, A.; Borja-Lloret, M.; Barrio, J.; Dendooven, P.; Oliver, J.F.; Ozoemelam, I.; Roser, J.; Llosa, G. |
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Title |
Proton range verification with MACACO II Compton camera enhanced by a neural network for event selection |
Type |
Journal Article |
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Year |
2021 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
11 |
Issue |
1 |
Pages |
9325 - 12pp |
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Keywords |
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Abstract |
The applicability extent of hadron therapy for tumor treatment is currently limited by the lack of reliable online monitoring techniques. An active topic of investigation is the research of monitoring systems based on the detection of secondary radiation produced during treatment. MACACO, a multi-layer Compton camera based on LaBr3 scintillator crystals and SiPMs, is being developed at IFIC-Valencia for this purpose. This work reports the results obtained from measurements of a 150 MeV proton beam impinging on a PMMA target. A neural network trained on Monte Carlo simulations is used for event selection, increasing the signal to background ratio before image reconstruction. Images of the measured prompt gamma distributions are reconstructed by means of a spectral reconstruction code, through which the 4.439 MeV spectral line is resolved. Images of the emission distribution at this energy are reconstructed, allowing calculation of the distal fall-off and identification of target displacements of 3 mm. |
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Address |
[Munoz, Enrique; Ros, Ana; Borja-Lloret, Marina; Barrio, John; Oliver, Josep F.; Roser, Jorge; Llosa, Gabriela] Univ Valencia, Inst Fis Corpuscular IFIC, CSIC, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es |
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Nature Research |
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English |
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2045-2322 |
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Notes |
WOS:000651603500001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4836 |
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Author |
Angles-Castillo, A.; Perez, A. |
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Title |
A quantum walk simulation of extra dimensions with warped geometry |
Type |
Journal Article |
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Year |
2022 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
12 |
Issue |
1 |
Pages |
1926 - 12pp |
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Abstract |
We investigate the properties of a quantum walk which can simulate the behavior of a spin 1/2 particle in a model with an ordinary spatial dimension, and one extra dimension with warped geometry between two branes. Such a setup constitutes a 1+ 1 dimensional version of the Randall-Sundrum model, which plays an important role in high energy physics. In the continuum spacetime limit, the quantum walk reproduces the Dirac equation corresponding to the model, which allows to anticipate some of the properties that can be reproduced by the quantum walk. In particular, we observe that the probability distribution becomes, at large time steps, concentrated near the “low energy” brane, and can be approximated as the lowest eigenstate of the continuum Hamiltonian that is compatible with the symmetries of the model. In this way, we obtain a localization effect whose strength is controlled by a warp coefficient. In other words, here localization arises from the geometry of the model, at variance with the usual effect that is originated from random irregularities, as in Anderson localization. In summary, we establish an interesting correspondence between a high energy physics model and localization in quantum walks. |
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Address |
[Angles-Castillo, Andreu] Univ Valencia, CSIC, Dept Fis Teor, Valencia 46100, Spain, Email: andreu.angles@ific.uv.es |
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Nature Portfolio |
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English |
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2045-2322 |
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Conference |
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Notes |
WOS:000751472600024 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5107 |
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Author |
Lerendegui-Marco, J.; Balibrea-Correa, J.; Babiano-Suarez, V.; Ladarescu, I.; Domingo-Pardo, C. |
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Title |
Towards machine learning aided real-time range imaging in proton therapy |
Type |
Journal Article |
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Year |
2022 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
12 |
Issue |
1 |
Pages |
2735 - 17pp |
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Abstract |
Compton imaging represents a promising technique for range verification in proton therapy treatments. In this work, we report on the advantageous aspects of the i-TED detector for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that have been specifically designed for neutron-capture nuclear physics experiments, which are characterized by gamma-ray energies spanning up to 5-6 MeV, rather low gamma-ray emission yields and very intense neutron induced gamma-ray backgrounds. Our developments to cope with these three aspects are concomitant with those required in the field of hadron therapy, especially in terms of high efficiency for real-time monitoring, low sensitivity to neutron backgrounds and reliable performance at the high gamma-ray energies. We find that signal-to-background ratios can be appreciably improved with i-TED thanks to its light-weight design and the low neutron-capture cross sections of its LaCl3 crystals, when compared to other similar systems based on LYSO, CdZnTe or LaBr3. Its high time-resolution (CRT similar to 500 ps) represents an additional advantage for background suppression when operated in pulsed HT mode. Each i-TED Compton module features two detection planes of very large LaCl3 monolithic crystals, thereby achieving a high efficiency in coincidence of 0.2% for a point-like 1 MeV gamma-ray source at 5 cm distance. This leads to sufficient statistics for reliable image reconstruction with an array of four i-TED detectors assuming clinical intensities of 10(8) protons per treatment point. The use of a two-plane design instead of three-planes has been preferred owing to the higher attainable efficiency for double time-coincidences than for threefold events. The loss of full-energy events for high energy gamma-rays is compensated by means of machine-learning based algorithms, which allow one to enhance the signal-to-total ratio up to a factor of 2. |
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Address |
[Lerendegui-Marco, Jorge; Balibrea-Correa, Javier; Babiano-Suarez, Victor; Ladarescu, Ion; Domingo-Pardo, Cesar] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: jorge.lerendegui@ific.uv.es |
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Nature Portfolio |
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English |
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ISSN |
2045-2322 |
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Conference |
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Notes |
WOS:000757537100018 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5136 |
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Author |
Tortajada, S.; Albiol, F.; Caballero, L.; Albiol, A.; Leganes-Nieto, J.L. |
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Title |
A portable geometry-independent tomographic system for gamma-ray, a next generation of nuclear waste characterization |
Type |
Journal Article |
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Year |
2023 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
13 |
Issue |
1 |
Pages |
12284 - 10pp |
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Keywords |
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Abstract |
One of the main activities of the nuclear industry is the characterisation of radioactive waste based on the detection of gamma radiation. Large volumes of radioactive waste are classified according to their average activity, but often the radioactivity exceeds the maximum allowed by regulators in specific parts of the bulk. In addition, the detection of the radiation is currently based on static detection systems where the geometry of the bulk is fixed and well known. Furthermore, these systems are not portable and depend on the transport of waste to the places where the detection systems are located. However, there are situations where the geometry varies and where moving waste is complex. This is especially true in compromised situations.We present a new model for nuclear waste management based on a portable and geometry-independent tomographic system for three-dimensional image reconstruction for gamma radiation detection. The system relies on a combination of a gamma radiation camera and a visible camera that allows to visualise radioactivity using augmented reality and artificial computer vision techniques. This novel tomographic system has the potential to be a disruptive innovation in the nuclear industry for nuclear waste management. |
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Address |
[Tortajada, Salvador; Albiol, Francisco; Caballero, Luis] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Paterna Valencia, Spain, Email: s.tortajada@ific.uv.es |
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Publisher |
Nature Portfolio |
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English |
Summary Language |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2045-2322 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001041587900052 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5612 |
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Author |
Penas, J.; Alejo, A.; Bembibre, A.; Apiñaniz, J.I.; Garcia-Garcia, E.; Guerrero, C.; Henares, J.L.; Hernandez-Palmero, I.; Mendez, C.; Millan-Callado, M.A.; Puyuelo-Valdes, P.; Seimetz, M.; Benlliure, J. |
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Title |
Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source |
Type |
Journal Article |
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Year |
2024 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
14 |
Issue |
1 |
Pages |
11448 - 12pp |
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Keywords |
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Abstract |
Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range. |
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Address |
[Penas, Juan; Alejo, Aaron; Bembibre, Adrian; Benlliure, Jose] Univ Santiago de Compostela, Inst Galego Fis Altas Enerxias IGFAE, Santiago De Compostela 15782, Spain, Email: j.benlliure@usc.es |
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Publisher |
Nature Portfolio |
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English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISSN |
2045-2322 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001228252900017 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
6143 |
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Author |
Ureña, J.; Sojo, A.; Bermejo-Vega, J.; Manzano, D. |
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Title |
Entanglement detection with classical deep neural networks |
Type |
Journal Article |
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Year |
2024 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
14 |
Issue |
1 |
Pages |
18109 - 11pp |
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Keywords |
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Abstract |
In this study, we introduce an autonomous method for addressing the detection and classification of quantum entanglement, a core element of quantum mechanics that has yet to be fully understood. We employ a multi-layer perceptron to effectively identify entanglement in both two- and three-qubit systems. Our technique yields impressive detection results, achieving nearly perfect accuracy for two-qubit systems and over 90% accuracy for three-qubit systems. Additionally, our approach successfully categorizes three-qubit entangled states into distinct groups with a success rate of up to 77%. These findings indicate the potential for our method to be applied to larger systems, paving the way for advancements in quantum information processing applications. |
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Address |
[Urena, Julio] CSIC, Inst Fis Corpuscular IF, Valencia 46980, Spain, Email: manzano@onsager.ugr.es |
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Publisher |
Nature Portfolio |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISSN |
2045-2322 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001284942100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
6230 |
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Author |
ANTARES Collaboration (Albert, A. et al); Barrios-Marti, J.; Coleiro, A.; Colomer, M.; Hernandez-Rey, J.J.; Illuminati, G.; Khan-Chowdhury, N.R.; Lotze, M.; Zornoza, J.D.; Zuñiga, J. |
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Title |
The search for neutrinos from TXS 0506+056 with the ANTARES telescope |
Type |
Journal Article |
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Year |
2018 |
Publication |
Astrophysical Journal Letters |
Abbreviated Journal |
Astrophys. J. Lett. |
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Volume |
863 |
Issue |
2 |
Pages |
L30 - 6pp |
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Keywords |
astroparticle physics; elementary particles; galaxies: active |
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Abstract |
The results of three different searches for neutrino candidates, associated with the IceCube-170922A event or from the direction of TXS 0506+056, by the ANTARES neutrino telescope, are presented. The first search refers to the online follow-up of the IceCube alert; the second is based on the standard time-integrated method employed by the Collaboration to search for point-like neutrino sources; the third uses information from the IceCube time-dependent analysis that reported bursting activity centered on 2014 December 13, as input for an ANTARES time-dependent analysis. The online follow-up and the time-dependent analysis yield no events related to the source. The time-integrated study performed over a period from 2007 to 2017 fits 1.03 signal events, which corresponds to a p-value of 3.4% (not considering trial factors). Only for two other astrophysical objects in our candidate list has a smaller p-value been found. When considering that 107 sources have been investigated, the post-trial p-value for TXS 0506+056 corresponds to 87%. |
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Address |
[Albert, A.; Drouhin, D.; Ruiz, T. Gregoire; Organokov, M.; Pradier, T.] Univ Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg, France, Email: antares.spokesperson@in2p3.fr |
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Corporate Author |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2041-8205 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000442002100004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3697 |
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| Permanent link to this record |
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Author |
ANTARES and IceCube Collaborations (Albert, A. et al); Barrios-Marti, J.; Coleiro, A.; Colomer, M.; Hernandez-Rey, J.J.; Illuminati, G.; Khan-Chowdhury, N.R.; Lotze, M.; Zornoza, J.D.; Zuñiga, J. |
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Title |
Joint Constraints on Galactic Diffuse Neutrino Emission from the ANTARES and IceCube Neutrino Telescopes |
Type |
Journal Article |
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Year |
2018 |
Publication |
Astrophysical Journal Letters |
Abbreviated Journal |
Astrophys. J. Lett. |
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Volume |
868 |
Issue |
2 |
Pages |
L20 - 7pp |
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Keywords |
cosmic rays; diffusion; Galaxy: disk; gamma rays: diffuse background; neutrinos |
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Abstract |
The existence of diffuse Galactic neutrino production is expected from cosmic-ray interactions with Galactic gas and radiation fields. Thus, neutrinos are a unique messenger offering the opportunity to test the products of Galactic cosmic-ray interactions up to energies of hundreds of TeV. Here we present a search for this production using ten years of Astronomy with a Neutrino Telescope and Abyss environmental RESearch (ANTARES) track and shower data, as well as seven years of IceCube track data. The data are combined into a joint likelihood test for neutrino emission according to the KRA(gamma) model assuming a 5 PeV per nucleon Galactic cosmic-ray cutoff. No significant excess is found. As a consequence, the limits presented in this Letter start constraining the model parameter space for Galactic cosmic-ray production and transport. |
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Address |
[Albert, A.; Drouhin, D.; Ruiz, R. Gracia; Organokov, M.; Pradier, T.] Univ Strasbourg, CNRS, IPHC UMR 7178, F-67000 Strasbourg, France, Email: antares.spokeperson@in2p3.fr; |
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Corporate Author |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2041-8205 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000450844500004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3807 |
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Author |
HAWC Collaboration (Albert, A. et al); Salesa Greus, F. |
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Title |
HAWC J2227+610 and Its Association with G106.3+2.7, a New Potential Galactic PeVatron |
Type |
Journal Article |
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Year |
2020 |
Publication |
Astrophysical Journal Letters |
Abbreviated Journal |
Astrophys. J. Lett. |
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Volume |
896 |
Issue |
2 |
Pages |
L29 - 9pp |
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Keywords |
Gamma-ray astronomy; Gamma-ray sources; Gamma-rays; Cosmic ray sources; Supernova remnants; Gamma-ray observatories |
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Abstract |
We present the detection of very-high-energy gamma-ray emission above 100 TeV from HAWC J2227+610 with the High-Altitude Water Cherenov Gamma-Ray Observatory (HAWC) observatory. Combining our observations with previously published results by the Very Energetic Radiation Imaging Telescope Array System (VERTIAS), we interpret the gamma-ray emission from HAWC J2227+610 as emission from protons with a lower limit in their cutoff energy of 800 TeV. The most likely source of the protons is the associated supernova remnant G106.3+2.7, making it a good candidate for a Galactic PeVatron. However, a purely leptonic origin of the observed emission cannot be excluded at this time. |
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Address |
[Albert, A.; Dingus, B. L.; Harding, J. P.; Malone, K.; Sinnis, G.] Los Alamos Natl Lab, Phys Div, Los Alamos, NM 87545 USA, Email: hfleisch@mtu.edu |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2041-8205 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000542724600001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4445 |
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Author |
HAWC Collaboration (Albert, A. et al); Salesa Greus, F. |
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Title |
HAWC and Fermi-LAT Detection of Extended Emission from the Unidentified Source 2HWC J2006+341 |
Type |
Journal Article |
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Year |
2020 |
Publication |
Astrophysical Journal Letters |
Abbreviated Journal |
Astrophys. J. Lett. |
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Volume |
903 |
Issue |
1 |
Pages |
L14 - 6pp |
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Keywords |
Gamma-rays; Interstellar medium |
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Abstract |
The discovery of the TeV point source 2HWC J2006+341 was reported in the second HAWC gamma-ray catalog. We present a follow-up study of this source here. The TeV emission is best described by an extended source with a soft spectrum. At GeV energies, an extended source is significantly detected in Fermi-LAT data. The matching locations, sizes, and spectra suggest that both gamma-ray detections correspond to the same source. Different scenarios for the origin of the emission are considered and we rule out an association to the pulsar PSR J2004+3429 due to extreme energetics required, if located at a distance of 10.8 kpc. |
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Address |
[Albert, A.; Dingus, B. L.; Durocher, M.; Harding, J. P.; Malone, K.] Los Alamos Natl Lab, Phys Div, Los Alamos, NM USA, Email: miguel.araya@ucr.ac.cr |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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English |
Summary Language |
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Original Title |
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Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
2041-8205 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000584890800001 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
4591 |
|
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