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Botella-Soler, V., Valderrama, M., Crepon, B., Navarro, V., & Le Van Quyen, M. (2012). Large-Scale Cortical Dynamics of Sleep Slow Waves. PLoS One, 7(2), e30757–10pp.
Abstract: Slow waves constitute the main signature of sleep in the electroencephalogram (EEG). They reflect alternating periods of neuronal hyperpolarization and depolarization in cortical networks. While recent findings have demonstrated their functional role in shaping and strengthening neuronal networks, a large-scale characterization of these two processes remains elusive in the human brain. In this study, by using simultaneous scalp EEG and intracranial recordings in 10 epileptic subjects, we examined the dynamics of hyperpolarization and depolarization waves over a large extent of the human cortex. We report that both hyperpolarization and depolarization processes can occur with two different characteristic time durations which are consistent across all subjects. For both hyperpolarization and depolarization waves, their average speed over the cortex was estimated to be approximately 1 m/s. Finally, we characterized their propagation pathways by studying the preferential trajectories between most involved intracranial contacts. For both waves, although single events could begin in almost all investigated sites across the entire cortex, we found that the majority of the preferential starting locations were located in frontal regions of the brain while they had a tendency to end in posterior and temporal regions.
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Valderrama, M., Crepon, B., Botella-Soler, V., Martinerie, J., Hasboun, D., Alvarado-Rojas, C., et al. (2012). Human Gamma Oscillations during Slow Wave Sleep. PLoS One, 7(4), e33477–14pp.
Abstract: Neocortical local field potentials have shown that gamma oscillations occur spontaneously during slow-wave sleep (SWS). At the macroscopic EEG level in the human brain, no evidences were reported so far. In this study, by using simultaneous scalp and intracranial EEG recordings in 20 epileptic subjects, we examined gamma oscillations in cerebral cortex during SWS. We report that gamma oscillations in low (30-50 Hz) and high (60-120 Hz) frequency bands recurrently emerged in all investigated regions and their amplitudes coincided with specific phases of the cortical slow wave. In most of the cases, multiple oscillatory bursts in different frequency bands from 30 to 120 Hz were correlated with positive peaks of scalp slow waves (“IN-phase'' pattern), confirming previous animal findings. In addition, we report another gamma pattern that appears preferentially during the negative phase of the slow wave (”ANTI-phase'' pattern). This new pattern presented dominant peaks in the high gamma range and was preferentially expressed in the temporal cortex. Finally, we found that the spatial coherence between cortical sites exhibiting gamma activities was local and fell off quickly when computed between distant sites. Overall, these results provide the first human evidences that gamma oscillations can be observed in macroscopic EEG recordings during sleep. They support the concept that these high-frequency activities might be associated with phasic increases of neural activity during slow oscillations. Such patterned activity in the sleeping brain could play a role in off-line processing of cortical networks.
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Borja, E. F., Garay, I., & Vidotto, F. (2012). Learning about Quantum Gravity with a Couple of Nodes. Symmetry Integr. Geom., 8, 015–44pp.
Abstract: Loop Quantum Gravity provides a natural truncation of the infinite degrees of freedom of gravity, obtained by studying the theory on a given finite graph. We review this procedure and we present the construction of the canonical theory on a simple graph, formed by only two nodes. We review the U(N) framework, which provides a powerful tool for the canonical study of this model, and a formulation of the system based on spinors. We consider also the covariant theory, which permits to derive the model from a more complex formulation, paying special attention to the cosmological interpretation of the theory.
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Bates, R. L. et al, Bernabeu Verdú, J., Civera, J. V., Gonzalez, F., Lacasta, C., & Sanchez, J. (2012). The ATLAS SCT grounding and shielding concept and implementation. J. Instrum., 7, P03005.
Abstract: This paper describes the design and implementation of the grounding and shielding system for the ATLAS SemiConductor Tracker (SCT). The mitigation of electromagnetic interference and noise pickup through power lines is the critical design goal as they have the potential to jeopardize the electrical performance. We accomplish this by adhering to the ATLAS grounding rules, by avoiding ground loops and isolating the different subdetectors. Noise sources are identified and design rules to protect the SCT against them are described. A rigorous implementation of the design was crucial to achieve the required performance. This paper highlights the location, connection and assembly of the different components that affect the grounding and shielding system: cables, filters, cooling pipes, shielding enclosure, power supplies and others. Special care is taken with the electrical properties of materials and joints. The monitoring of the grounding system during the installation period is also discussed. Finally, after connecting more than four thousand SCT modules to all of their services, electrical, mechanical and thermal within the wider ATLAS experimental environment, dedicated tests show that noise pickup is minimised.
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NEXT Collaboration(Alvarez, V. et al), Agramunt, J., Ball, M., Bayarri, J., Carcel, S., Cervera-Villanueva, A., et al. (2012). SiPMs coated with TPB: coating protocol and characterization for NEXT. J. Instrum., 7, P02010.
Abstract: Silicon photomultipliers (SiPM) are the photon detectors chosen for the tracking read-out in NEXT, a neutrinoless beta beta decay experiment which uses a high pressure gaseous xenon time projection chamber (TPC). The reconstruction of event track and topology in this gaseous detector is a key handle for background rejection. Among the commercially available sensors that can be used for tracking, SiPMs offer important advantages, mainly high gain, ruggedness, cost-effectiveness and radio-purity. Their main drawback, however, is their non sensitivity in the emission spectrum of the xenon scintillation (peak at 175 nm). This is overcome by coating these sensors with the organic wavelength shifter tetraphenyl butadiene (TPB). In this paper we describe the protocol developed for coating the SiPMs with TPB and the measurements performed for characterizing the coatings as well as the performance of the coated sensors in the UV-VUV range.
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