Abstract: We investigate the eta' photoproduction off the nucleon with a particular interest in the effect of the final-state interaction (FSI) of the eta' meson and nucleon (eta' N) based on the three-flavor linear sigma model. We find an enhancement in the cross section of the eta' photoproduction near the eta' N-threshold energy owing to the eta' N FSI. With the eta' meson at forward angles, the energy dependence near the eta' N threshold is well reproduced with the eta' N FSI. The cross section at backward angles can also be a good probe to investigate the strength of the eta' N interaction.