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Beaulieu, L., Ballester, F., Granero, D., Tedgren, A. C., Haworth, A., Lowenstein, J. R., et al. (2023). AAPM WGDCAB Report 372: A joint AAPM, ESTRO, ABG, and ABS report on commissioning of model-based dose calculation algorithms in brachytherapy. Med. Phys., 50(8), e946–e960.
Abstract: The introduction of model-based dose calculation algorithms (MBDCAs) in brachytherapy provides an opportunity for a more accurate dose calculation and opens the possibility for novel, innovative treatment modalities. The joint AAPM, ESTRO, and ABG Task Group 186 (TG-186) report provided guidance to early adopters. However, the commissioning aspect of these algorithms was described only in general terms with no quantitative goals. This report, from the Working Group on Model-Based Dose Calculation Algorithms in Brachytherapy, introduced a field-tested approach to MBDCA commissioning. It is based on a set of well-characterized test cases for which reference Monte Carlo (MC) and vendor-specific MBDCA dose distributions are available in a Digital Imaging and Communications in Medicine-Radiotherapy (DICOM-RT) format to the clinical users. The key elements of the TG-186 commissioning workflow are now described in detail, and quantitative goals are provided. This approach leverages the well-known Brachytherapy Source Registry jointly managed by the AAPM and the Imaging and Radiation Oncology Core (IROC) Houston Quality Assurance Center (with associated links at ESTRO) to provide open access to test cases as well as step-by-step user guides. While the current report is limited to the two most widely commercially available MBDCAs and only for Ir-192-based afterloading brachytherapy at this time, this report establishes a general framework that can easily be extended to other brachytherapy MBDCAs and brachytherapy sources. The AAPM, ESTRO, ABG, and ABS recommend that clinical medical physicists implement the workflow presented in this report to validate both the basic and the advanced dose calculation features of their commercial MBDCAs. Recommendations are also given to vendors to integrate advanced analysis tools into their brachytherapy treatment planning system to facilitate extensive dose comparisons. The use of the test cases for research and educational purposes is further encouraged.
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Fletcher, E. M., Ballester, F., Beaulieu, L., Morrison, H., Poher, A., Rivard, M. J., et al. (2024). Generation and comparison of 3D dosimetric reference datasets for COMS eye plaque brachytherapy using model-based dose calculations. Med. Phys., 51, 694–706.
Abstract: PurposeA joint Working Group of the American Association of Physicists in Medicine (AAPM), the European Society for Radiotherapy and Oncology (ESTRO), and the Australasian Brachytherapy Group (ABG) was created to aid in the transition from the AAPM TG-43 dose calculation formalism, the current standard, to model-based dose calculations. This work establishes the first test cases for low-energy photon-emitting brachytherapy using model-based dose calculation algorithms (MBDCAs).Acquisition and Validation MethodsFive test cases are developed: (1) a single model 6711 125I brachytherapy seed in water, 13 seeds (2) individually and (3) in combination in water, (4) the full Collaborative Ocular Melanoma Study (COMS) 16-mm eye plaque in water, and (5) the full plaque in a realistic eye phantom. Calculations are done with four Monte Carlo (MC) codes and a research version of a commercial treatment planning system (TPS). For all test cases, local agreement of MC codes was within & SIM;2.5% and global agreement was & SIM;2% (4% for test case 5). MC agreement was within expected uncertainties. Local agreement of TPS with MC was within 5% for test case 1 and & SIM;20% for test cases 4 and 5, and global agreement was within 0.4% for test case 1 and 10% for test cases 4 and 5.Data Format and Usage NotesDose distributions for each set of MC and TPS calculations are available online () along with input files and all other information necessary to repeat the calculations.Potential ApplicationsThese data can be used to support commissioning of MBDCAs for low-energy brachytherapy as recommended by TGs 186 and 221 and AAPM Report 372. This work additionally lays out a sample framework for the development of test cases that can be extended to other applications beyond eye plaque brachytherapy.
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Piriz, G. H., Gonzalez-Sprinberg, G. A., Ballester, F., & Vijande, J. (2024). Dosimetry of Large Field Valencia applicators for Cobalt-60-based brachytherapy. Med. Phys., , 5pp.
Abstract: BackgroundNon-melanoma skin cancer is one of the most common types of cancer and one of the main approaches is brachytherapy. For small lesions, the treatment of this cancer with brachytherapy can be done with two commercial applicators, one of these is the Large Field Valencia Applicators (LFVA).PurposeThe aim of this study is to test the capabilities of the LFVA to use clinically 60Co sources instead of the 192Ir ones. This study was designed for the same dwell positions and weights for both sources.MethodsThe Penelope Monte Carlo code was used to evaluate dose distribution in a water phantom when a 60Co source is considered. The LFVA design and the optimized dwell weights reported for the case of 192Ir are maintained with the only exception of the dwell weight of the central position, that was increased. 2D dose distributions, field flatness, symmetry and the leakage dose distribution around the applicator were calculated.ResultsWhen comparing the dose distributions of both sources, field flatness and symmetry remain unchanged. The only evident difference is an increase of the penumbra regions for all depths when using the 60Co source. Regarding leakage, the maximum dose within the air volume surrounding the applicator is in the order of 20% of the prescription dose for the 60Co source, but it decreases to less than 5% at about 1 cm distance.ConclusionsFlatness and symmetry remains unaltered as compared with 192Ir sources, while an increase in leakage has been observed. This proves the feasibility of using the LFVA in a larger range of clinical applications.
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Fanchiotti, H., Garcia Canal, C. A., Mayosky, M., Veiga, A., & Vento, V. (2023). The Geometric Phase in Classical Systems and in the Equivalent Quantum Hermitian and Non-Hermitian PT-Symmetric Systems. Braz. J. Phys., 53(6), 143–11pp.
Abstract: The decomplexification procedure allows one to show mathematically (stricto sensu) the equivalence (isomorphism) between the quantum dynamics of a system with a finite number of basis states and a classical dynamics system. This unique way of connecting different dynamics was used in the past to analyze the relationship between the well-known geometric phase present in the quantum evolution discovered by Berry and its generalizations, with their analogs, the Hannay phases, in the classical domain. In here, this analysis is carried out for several quantum hermitian and non-hermitian PT-symmetric Hamiltonians and compared with the Hannay phase analysis in their classical isomorphic equivalent systems. As the equivalence ends in the classical domain with oscillator dynamics, we exploit the analogy to propose resonant electric circuits coupled with a gyrator, to reproduce the geometric phase coming from the theoretical solutions, in simulated laboratory experiments.
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Garcia Canal, C. A., Tarutina, T., & Vento, V. (2023). Analysis of Nuclear Effects in Structure Functions and Their Connection with the Binding Energy of Nuclei. Braz. J. Phys., 53(6), 161–8pp.
Abstract: We describe nuclear effects in structure functions of nuclei in DIS by means of a multiplicative factor beta(A)(x) which differentiates the structure function of the bound nucleons from that of the free nucleons. Our analysis determines that beta(A)(x) establishes a relation between the quark-gluon dynamics expressed by the bound nucleon structure functions and the nuclear dynamics as described by the well-known semi-empirical Bethe-Weizsacker mass formula. This relation corroborates a connection between the underlying quark-gluon dynamics and the phenomenological nuclear dynamics.
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PTOLEMY Collaboration(Betti, M. G. et al), de Salas, P. F., Gariazzo, S., & Pastor, S. (2019). A design for an electromagnetic filter for precision energy measurements at the tritium endpoint. Prog. Part. Nucl. Phys., 106, 120–131.
Abstract: We present a detailed description of the electromagnetic filter for the PTOLEMY project to directly detect the Cosmic Neutrino Background (CNB). Starting with an initial estimate for the orbital magnetic moment, the higher-order drift process of E x B is configured to balance the gradient-B drift motion of the electron in such a way as to guide the trajectory into the standing voltage potential along the mid-plane of the filter. As a function of drift distance along the length of the filter, the filter zooms in with exponentially increasing precision on the transverse velocity component of the electron kinetic energy. This yields a linear dimension for the total filter length that is exceptionally compact compared to previous techniques for electromagnetic filtering. The parallel velocity component of the electron kinetic energy oscillates in an electrostatic harmonic trap as the electron drifts along the length of the filter. An analysis of the phase-space volume conservation validates the expected behavior of the filter from the adiabatic invariance of the orbital magnetic moment and energy conservation following Liouville's theorem for Hamiltonian systems. (C) 2019 Elsevier B.V. All rights reserved.
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Davesne, D., Pastore, A., & Navarro, J. (2021). Linear response theory with finite-range interactions. Prog. Part. Nucl. Phys., 120, 103870–55pp.
Abstract: This review focuses on the calculation of infinite nuclear matter response functions using phenomenological finite-range interactions, equipped or not with tensor terms. These include Gogny and Nakada families, which are commonly used in the literature. Because of the finite-range, the main technical difficulty stems from the exchange terms of the particle-hole interaction. We first present results based on the so-called Landau and Landau-like approximations of the particle-hole interaction. Then, we review two methods which in principle provide numerically exact response functions. The first one is based on a multipolar expansion of both the particle-hole interaction and the particle-hole propagator and the second one consists in a continued fraction expansion of the response function. The numerical precision can be pushed to any degree of accuracy, but it is actually shown that two or three terms suffice to get converged results. Finally, we apply the formalism to the determination of possible finite-size instabilities induced by a finite-range interaction.
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Pich, A. (2021). Precision physics with inclusive QCD processes. Prog. Part. Nucl. Phys., 117, 103846–41pp.
Abstract: The inclusive production of hadrons through electroweak currents can be rigorously analysed with short-distance theoretical tools. The associated observables are insensitive to the involved infrared behaviour of the strong interaction, allowing for very precise tests of Quantum Chromodynamics. The theoretical predictions for sigma(e(+)e(-) -> hadrons) and the hadronic decay widths of the tau lepton and the Z, W and Higgs bosons have reached an impressive accuracy of O(alpha(4)(s)). Precise experimental measurements of the Z and tau hadronic widths have made possible the accurate determination of the strong coupling at two very different energy scales, providing a highly significant experimental verification of asymptotic freedom. A detailed discussion of the theoretical description of these processes and their current phenomenological status is presented. The most precise determinations of alpha(s) from other sources are also briefly reviewed and compared with the fully-inclusive results.
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Addazi, A. et al, Martinez-Mirave, P., Mitsou, V. A., Palomares-Ruiz, S., Tortola, M., & Zornoza, J. D. (2022). Quantum gravity phenomenology at the dawn of the multi-messenger era-A review. Prog. Part. Nucl. Phys., 125, 103948–119pp.
Abstract: The exploration of the universe has recently entered a new era thanks to the multi-messenger paradigm, characterized by a continuous increase in the quantity and quality of experimental data that is obtained by the detection of the various cosmic messengers (photons, neutrinos, cosmic rays and gravitational waves) from numerous origins. They give us information about their sources in the universe and the properties of the intergalactic medium. Moreover, multi-messenger astronomy opens up the possibility to search for phenomenological signatures of quantum gravity. On the one hand, the most energetic events allow us to test our physical theories at energy regimes which are not directly accessible in accelerators; on the other hand, tiny effects in the propagation of very high energy particles could be amplified by cosmological distances. After decades of merely theoretical investigations, the possibility of obtaining phenomenological indications of Planck-scale effects is a revolutionary step in the quest for a quantum theory of gravity, but it requires cooperation between different communities of physicists (both theoretical and experimental). This review, prepared within the COST Action CA18108 “Quantum gravity phenomenology in the multi-messenger approach”, is aimed at promoting this cooperation by giving a state-of-the art account of the interdisciplinary expertise that is needed in the effective search of quantum gravity footprints in the production, propagation and detection of cosmic messengers.
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Albaladejo, M., Bibrzycki, L., Dawid, S. M., Fernandez-Ramirez, C., Gonzalez-Solis, S., Hiller Blin, A. N., et al. (2022). Novel approaches in hadron spectroscopy. Prog. Part. Nucl. Phys., 127, 103981–75pp.
Abstract: The last two decades have witnessed the discovery of a myriad of new and unexpected hadrons. The future holds more surprises for us, thanks to new-generation experiments. Understanding the signals and determining the properties of the states requires a parallel theoretical effort. To make full use of available and forthcoming data, a careful amplitude modeling is required, together with a sound treatment of the statistical uncertainties, and a systematic survey of the model dependencies. We review the contributions made by the Joint Physics Analysis Center to the field of hadron spectroscopy.
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