Du, M. L., Filin, A., Baru, V., Dong, X. K., Epelbaum, E., Guo, F. K., et al. (2023). Role of Left-Hand Cut Contributions on Pole Extractions from Lattice Data: Case Study for Tcc(3875)+. Phys. Rev. Lett., 131(13), 131903–7pp.
Abstract: We discuss recent lattice data for the T-cc(3875)(+) state to stress, for the first time, a potentially strong impact of left-hand cuts from the one-pion exchange on the pole extraction for near-threshold exotic states. In particular, if the left-hand cut is located close to the two-particle threshold, which happens naturally in the DD* system for the pion mass exceeding its physical value, the effective-range expansion is valid only in a very limited energy range up to the cut and as such is of little use to reliably extract the poles. Then, an accurate extraction of the pole locations requires the one-pion exchange to be implemented explicitly into the scattering amplitudes. Our findings are general and potentially relevant for a wide class of hadronic near-threshold states.
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ATLAS Collaboration(Aad, G. et al), Amos, K. R., Aparisi Pozo, J. A., Bailey, A. J., Bouchhar, N., Cabrera Urban, S., et al. (2023). Measurement of Suppression of Large-Radius Jets and Its Dependence on Substructure in Pb plus Pb Collisions at √sNN=5.02 TeV with the ATLAS Detector. Phys. Rev. Lett., 131(17), 172301–22pp.
Abstract: This letter presents a measurement of the nuclear modification factor of large-radius jets in root s(NN) = 5.02 TeV Pb thorn Pb collisions by the ATLAS experiment. The measurement is performed using 1.72 nb(-1) and 257 pb(-1) of Pb thorn Pb and pp data, respectively. The large-radius jets are reconstructed with the anti-kt algorithm using a radius parameter of R = 1.0, by reclustering anti-k(t) R = 0.2 jets, and are measured over the transverse momentum (p(T)) kinematic range of 158 < p(T) < 1000 GeV and absolute pseudorapidity |y| < 2.0. The large-radius jet constituents are further reclustered using the k(t) algorithm in order to obtain the splitting parameters, root d(12) and Delta R-12, which characterize the transverse momentum scale and angular separation for the hardest splitting in the jet, respectively. The nuclear modification factor, R-AA, obtained by comparing the Pb thorn Pb jet yields to those in pp collisions, is measured as a function of jet transverse momentum (p(T)) and root d(12) or Delta R-12. A significant difference in the quenching of large-radius jets having single subjet and those with more complex substructure is observed. Systematic comparison of jet suppression in terms of R-AA for different jet definitions is also provided. Presented results support the hypothesis that jets with hard internal splittings lose more energy through quenching and provide a new perspective for understanding the role of jet structure in jet suppression.
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Figueroa, D. G., Pieroni, M., Ricciardone, A., & Simakachorn, P. (2024). Cosmological Background Interpretation of Pulsar Timing Array Data. Phys. Rev. Lett., 132(17), 171002–9pp.
Abstract: We discuss the interpretation of the detected signal by pulsar timing array (PTA) observations as a gravitational wave background of cosmological origin. We combine NANOGrav 15-years and EPTADR2new datasets and confront them against backgrounds from supermassive black hole binaries (SMBHBs), and cosmological signals from inflation, cosmic (super)strings, first-order phase transitions, Gaussian and non-Gaussian large scalar fluctuations, and audible axions. We find that scalar-induced, and to a lesser extent audible axion and cosmic superstring signals, provide a better fit than SMBHBs. These results depend, however, on modeling assumptions, so further data and analysis are needed to reach robust conclusions. Independently of the signal origin, the data strongly constrain the parameter space of cosmological signals, for example, setting an upper bound on primordial non-Gaussianity at PTA scales as jfnlj less than or similar to 2.34 at 95% C.L.
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LHCb Collaboration(Aaij, R. et al), Jaimes Elles, S. J., Jashal, B. K., Martinez Vidal, F., Oyanguren, A., Rebollo De Miguel, M., et al. (2023). Search for Rare Decays of D0 Mesons into Two Muons. Phys. Rev. Lett., 131(4), 041804–13pp.
Abstract: A search for the very rare D-0 -> mu(+)mu(-) decay is performed using data collected by the LHCb experiment in proton-proton collisions at root s = 7, 8, and 13 TeV, corresponding to an integrated luminosity of 9 fb(-1). The search is optimized for D-0 mesons from D*(+) -> D-0 pi(+) decays but is also sensitive to D-0 mesons from other sources. No evidence for an excess of events over the expected background is observed. An upper limit on the branching fraction of this decay is set at B(D-0 -> mu(+)mu(-)) < 3.1 x 10(-9) at a 90% C.L. This represents the world's most stringent limit, constraining models of physics beyond the standard model.
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Etxebeste, A., Barrio, J., Muñoz, E., Oliver, J. F., Solaz, C., & Llosa, G. (2016). 3D position determination in monolithic crystals coupled to SiPMs for PET. Phys. Med. Biol., 61(10), 3914–3934.
Abstract: The interest in using continuous monolithic crystals in positron emission tomography (PET) has grown in the last years. Coupled to silicon photomultipliers (SiPMs), the detector can combine high sensitivity and high resolution, the two main factors to be maximized in a positron emission tomograph. In this work, the position determination capability of a detector comprised of a 12 x 12 x 10 mm(3) LYSO crystal coupled to an 8 x 8-pixel array of SiPMs is evaluated. The 3D interaction position of.-rays is estimated using an analytical model of the light distribution including reflections on the facets of the crystal. Monte Carlo simulations have been performed to evaluate different crystal reflectors and geometries. The method has been characterized and applied to different cases. Intrinsic resolution obtained with the position estimation method used in this work, applied to experimental data, achieves sub-millimetre resolution values. Average resolution over the detector surface for 5 mm thick crystal is similar to 0.9 mm FWHM and similar to 1.2 mm FWHM for 10 mm thick crystal. Depth of interaction resolution is close to 2 mm FWHM in both cases, while the FWTM is similar to 5.3 mm for 5 mm thick crystal and similar to 9.6 mm for 10 mm thick crystal.
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Solevi, P., Muñoz, E., Solaz, C., Trovato, M., Dendooven, P., Gillam, J. E., et al. (2016). Performance of MACACO Compton telescope for ion-beam therapy monitoring: first test with proton beams. Phys. Med. Biol., 61(14), 5149–5165.
Abstract: In order to exploit the advantages of ion-beam therapy in a clinical setting, delivery verification techniques are necessary to detect deviations from the planned treatment. Efforts are currently oriented towards the development of devices for real-time range monitoring. Among the different detector concepts proposed, Compton cameras are employed to detect prompt gammas and represent a valid candidate for real-time range verification. We present the first on-beam test of MACACO, a Compton telescope (multi-layer Compton camera) based on lanthanum bromide crystals and silicon photo-multipliers. The Compton telescope was first characterized through measurements and Monte Carlo simulations. The detector linearity was measured employing Na-22 and Am-Be sources, obtaining about 10% deviation from linearity at 3.44 MeV. A spectral image reconstruction algorithm was tested on synthetic data. Point-like sources emitting gamma rays with energy between 2 and 7 MeV were reconstructed with 3-5 mm resolution. The two-layer Compton telescope was employed to measure radiation emitted from a beam of 150 MeV protons impinging on a cylindrical PMMA target. Bragg-peak shifts were achieved via adjustment of the PMMA target location and the resulting measurements used during image reconstruction. Reconstructed Bragg peak profiles proved sufficient to observe peak-location differences within 10 mm demonstrating the potential of the MACACO Compton Telescope as a monitoring device for ion-beam therapy.
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Muñoz, E., Barrio, J., Etxebeste, A., Ortega, P. G., Lacasta, C., Oliver, J. F., et al. (2017). Performance evaluation of MACACO: a multilayer Compton camera. Phys. Med. Biol., 62(18), 7321–7341.
Abstract: Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm.
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Gimenez-Alventosa, V., Gimenez, V., Ballester, F., Vijande, J., & Andreo, P. (2018). Correction factors for ionization chamber measurements with the 'Valencia' and 'large field Valencia' brachytherapy applicators. Phys. Med. Biol., 63(12), 125004–10pp.
Abstract: Treatment of small skin lesions using HDR brachytherapy applicators is a widely used technique. The shielded applicators currently available in clinical practice are based on a tungsten-alloy cup that collimates the source-emitted radiation into a small region, hence protecting nearby tissues. The goal of this manuscript is to evaluate the correction factors required for dose measurements with a plane-parallel ionization chamber typically used in clinical brachytherapy for the 'Valencia' and 'large field Valencia' shielded applicators. Monte Carlo simulations have been performed using the PENELOPE-2014 system to determine the absorbed dose deposited in a water phantom and in the chamber active volume with a Type A uncertainty of the order of 0.1%. The average energies of the photon spectra arriving at the surface of the water phantom differ by approximately 10%, being 384 keV for the 'Valencia' and 343 keV for the 'large field Valencia'. The ionization chamber correction factors have been obtained for both applicators using three methods, their values depending on the applicator being considered. Using a depth-independent global chamber perturbation correction factor and no shift of the effective point of measurement yields depth-dose differences of up to 1% for the 'Valencia' applicator. Calculations using a depth-dependent global perturbation factor, or a shift of the effective point of measurement combined with a constant partial perturbation factor, result in differences of about 0.1% for both applicators. The results emphasize the relevance of carrying out detailed Monte Carlo studies for each shielded brachytherapy applicator and ionization chamber.
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Muñoz, E., Barrio, J., Bernabeu, J., Etxebeste, A., Lacasta, C., Llosa, G., et al. (2018). Study and comparison of different sensitivity models for a two-plane Compton camera. Phys. Med. Biol., 63(13), 135004–19pp.
Abstract: Given the strong variations in the sensitivity of Compton cameras for the detection of events originating from different points in the field of view (FoV), sensitivity correction is often necessary in Compton image reconstruction. Several approaches for the calculation of the sensitivity matrix have been proposed in the literature. While most of these models are easily implemented and can be useful in many cases, they usually assume high angular coverage over the scattered photon, which is not the case for our prototype. In this work, we have derived an analytical model that allows us to calculate a detailed sensitivity matrix, which has been compared to other sensitivity models in the literature. Specifically, the proposed model describes the probability of measuring a useful event in a two-plane Compton camera, including the most relevant physical processes involved. The model has been used to obtain an expression for the system and sensitivity matrices for iterative image reconstruction. These matrices have been validated taking Monte Carlo simulations as a reference. In order to study the impact of the sensitivity, images reconstructed with our sensitivity model and with other models have been compared. Images have been reconstructed from several simulated sources, including point-like sources and extended distributions of activity, and also from experimental data measured with Na-22 sources. Results show that our sensitivity model is the best suited for our prototype. Although other models in the literature perform successfully in many scenarios, they are not applicable in all the geometrical configurations of interest for our system. In general, our model allows to effectively recover the intensity of point-like sources at different positions in the FoV and to reconstruct regions of homogeneous activity with minimal variance. Moreover, it can be employed for all Compton camera configurations, including those with low angular coverage over the scatterer.
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Etxebeste, A., Barrio, J., Bernabeu, J., Lacasta, C., Llosa, G., Muñoz, E., et al. (2019). Study of sensitivity and resolution for full ring PET prototypes based on continuous crystals and analytical modeling of the light distribution. Phys. Med. Biol., 64(3), 035015–17pp.
Abstract: Sensitivity and spatial resolution are the main parameters to maximize in the performance of a PET scanner. For this purpose, detectors consisting of a combination of continuous crystals optically coupled to segmented photodetectors have been employed. With the use of continuous crystals the sensitivity is increased with respect to the pixelated crystals. In addition, spatial resolution is no longer limited to the crystal size. The main drawback is the difficulty in determining the interaction position. In this work, we present the characterization of the performance of a full ring based on cuboid continuous crystals coupled to SiPMs. To this end, we have employed the simulations developed in a previous work for our experimental detector head. Sensitivity could be further enhanced by using tapered crystals. This enhancement is obtained by increasing the solid angle coverage, reducing the wedge-shaped gaps between contiguous detectors. The performance of the scanners based on both crystal geometries was characterized following NEMA NU 4-2008 standardized protocol in order to compare them. An average sensitivity gain over the entire axial field of view of 13.63% has been obtained with tapered geometry while similar performance of the spatial resolution has been proven with both scanners. The activity at which NECR and true peak occur is smaller and the peak value is greater for tapered crystals than for cuboid crystals. Moreover, a higher degree of homogeneity was obtained in the sensitivity map due to the tighter packing of the crystals, which reduces the gaps and results in a better recovery of homogeneous regions than for the cuboid configuration. Some of the results obtained, such as spatial resolution, depend on the interaction position estimation and may vary if other method is employed.
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