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Author |
Brzezinski, K. et al |
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Title |
Detection of range shifts in proton beam therapy using the J-PET scanner: a patient simulation study |
Type |
Journal Article |
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Year |
2023 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
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Volume |
68 |
Issue |
14 |
Pages |
145016 - 17pp |
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Keywords |
proton therapy; positron emission tomography; in vivo range verification; J-PET; Monte Carlo |
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Abstract |
Objective. The Jagiellonian positron emission tomography (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasibility of using J-PET for range monitoring by means of a detailed Monte Carlo simulation study of 95 patients who underwent proton therapy at the Cyclotron Centre Bronowice (CCB) in Krakow, Poland. Approach. Discrepancies between prescribed and delivered treatments were artificially introduced in the simulations by means of shifts in patient positioning and in the Hounsfield unit to the relative proton stopping power calibration curve. A dual-layer, cylindrical J-PET geometry was simulated in an in-room monitoring scenario and a triple-layer, dual-head geometry in an in-beam protocol. The distribution of range shifts in reconstructed PET activity was visualized in the beam's eye view. Linear prediction models were constructed from all patients in the cohort, using the mean shift in reconstructed PET activity as a predictor of the mean proton range deviation. Main results. Maps of deviations in the range of reconstructed PET distributions showed agreement with those of deviations in dose range in most patients. The linear prediction model showed a good fit, with coefficient of determination r (2) = 0.84 (in-room) and 0.75 (in-beam). Residual standard error was below 1 mm: 0.33 mm (in-room) and 0.23 mm (in-beam). Significance. The precision of the proposed prediction models shows the sensitivity of the proposed J-PET scanners to shifts in proton range for a wide range of clinical treatment plans. Furthermore, it motivates the use of such models as a tool for predicting proton range deviations and opens up new prospects for investigations into the use of intra-treatment PET images for predicting clinical metrics that aid in the assessment of the quality of delivered treatment. |
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Address |
[Brzezinski, Karol; Gajewski, Jan; Kopec, Renata; Olko, Pawel; Stasica, Paulina; Rucinski, Antoni] Polish Acad Sci, Inst Nucl Phys, Krakow, Poland, Email: karol.brzezinski@ific.uv.es |
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IOP Publishing Ltd |
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English |
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0031-9155 |
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Notes |
WOS:001026535700001 |
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no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5616 |
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Author |
Gisbert, H.; Pich, A. |
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Title |
Direct CP violation in K-0 -> pi pi : Standard Model Status |
Type |
Journal Article |
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Year |
2018 |
Publication |
Reports on Progress in Physics |
Abbreviated Journal |
Rep. Prog. Phys. |
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Volume |
81 |
Issue |
7 |
Pages |
076201 - 22pp |
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Keywords |
Kaon decays; CP violation; Standard Model |
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Abstract |
In 1988 the NA31 experiment presented the first evidence of direct CP violation in the K-0 -> pi pi decay amplitudes. A clear signal with a 7.2 sigma statistical significance was later established with the full data samples from the NA31, E731, NA48 and KTeV experiments, confirming that CP violation is associated with a Delta S = 1 quark transition, as predicted by the Standard Model. However, the theoretical prediction for the measured ratio epsilon'/epsilon has been a subject of strong controversy along the years. Although the underlying physics was already clarified in 2001, the recent release of improved lattice data has revived again the theoretical debate. We review the current status, discussing in detail the different ingredients that enter into the calculation of this observable and the reasons why seemingly contradictory predictions were obtained in the past by several groups. An update of the Standard Model prediction is presented and the prospects for future improvements are analysed. Taking into account all known short-distance and long-distance contributions, one obtains Re (epsilon' / epsilon) = (15 +/- 7) . 10(-4), in good agreement with the experimental measurement. |
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Address |
[Gisbert, Hector; Pich, Antonio] Univ Valencia, CSIC, IFIC, Dept Fis Teor, Apt Correus 22085, E-46071 Valencia, Spain, Email: Antonio.Pich@ific.uv.es |
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Iop Publishing Ltd |
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English |
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0034-4885 |
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Notes |
WOS:000436545600001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
3641 |
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Author |
Curtin, D. et al; Hirsch, M. |
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Title |
Long-lived particles at the energy frontier: the MATHUSLA physics case |
Type |
Journal Article |
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Year |
2019 |
Publication |
Reports on Progress in Physics |
Abbreviated Journal |
Rep. Prog. Phys. |
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Volume |
82 |
Issue |
11 |
Pages |
116201 - 133pp |
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Keywords |
Large Hadron Collider; long-lived particles; hierarchy problem; dark matter; baryogenesis; neutrinos; simplified models |
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Abstract |
We examine the theoretical motivations for long-lived particle (LLP) signals at the LHC in a comprehensive survey of standard model (SM) extensions. LLPs are a common prediction of a wide range of theories that address unsolved fundamental mysteries such as naturalness, dark matter, baryogenesis and neutrino masses, and represent a natural and generic possibility for physics beyond the SM (BSM). In most cases the LLP lifetime can be treated as a free parameter from the μm scale up to the Big Bang Nucleosynthesis limit of similar to 10(7) m. Neutral LLPs with lifetimes above similar to 100 m are particularly difficult to probe, as the sensitivity of the LHC main detectors is limited by challenging backgrounds, triggers, and small acceptances. MATHUSLA is a proposal for a minimally instrumented, large-volume surface detector near ATLAS or CMS. It would search for neutral LLPs produced in HL-LHC collisions by reconstructing displaced vertices (DVs) in a low-background environment, extending the sensitivity of the main detectors by orders of magnitude in the long-lifetime regime. We study the LLP physics opportunities afforded by a MATHUSLA-like detector at the HL-LHC, assuming backgrounds can be rejected as expected. We develop a model-independent approach to describe the sensitivity of MATHUSLA to BSM LLP signals, and compare it to DV and missing energy searches at ATLAS or CMS. We then explore the BSM motivations for LLPs in considerable detail, presenting a large number of new sensitivity studies. While our discussion is especially oriented towards the long-lifetime regime at MATHUSLA, this survey underlines the importance of a varied LLP search program at the LHC in general. By synthesizing these results into a general discussion of the top-down and bottom-up motivations for LLP searches, it is our aim to demonstrate the exceptional strength and breadth of the physics case for the construction of the MATHUSLA detector. |
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Address |
[Curtin, David] Univ Toronto, Dept Phys, Toronto, ON M5S 1A7, Canada, Email: dcurtin@physics.utoronto.ca |
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Publisher |
Iop Publishing Ltd |
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English |
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ISSN |
0034-4885 |
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Notes |
WOS:000499698000001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4215 |
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Permanent link to this record |
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Author |
Kasieczka, G. et al; Sanz, V. |
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Title |
The LHC Olympics 2020: a community challenge for anomaly detection in high energy physics |
Type |
Journal Article |
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Year |
2021 |
Publication |
Reports on Progress in Physics |
Abbreviated Journal |
Rep. Prog. Phys. |
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Volume |
84 |
Issue |
12 |
Pages |
124201 - 64pp |
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Keywords |
anomaly detection; machine learning; unsupervised learning; weakly supervised learning; semisupervised learning; beyond the standard model; model-agnostic methods |
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Abstract |
A new paradigm for data-driven, model-agnostic new physics searches at colliders is emerging, and aims to leverage recent breakthroughs in anomaly detection and machine learning. In order to develop and benchmark new anomaly detection methods within this framework, it is essential to have standard datasets. To this end, we have created the LHC Olympics 2020, a community challenge accompanied by a set of simulated collider events. Participants in these Olympics have developed their methods using an R&D dataset and then tested them on black boxes: datasets with an unknown anomaly (or not). Methods made use of modern machine learning tools and were based on unsupervised learning (autoencoders, generative adversarial networks, normalizing flows), weakly supervised learning, and semi-supervised learning. This paper will review the LHC Olympics 2020 challenge, including an overview of the competition, a description of methods deployed in the competition, lessons learned from the experience, and implications for data analyses with future datasets as well as future colliders. |
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Address |
[Kasieczka, Gregor] Univ Hamburg, Inst Expt Phys, Hamburg, Germany, Email: gregor.kasieczka@uni-hamburg.de; |
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Publisher |
IOP Publishing Ltd |
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English |
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ISSN |
0034-4885 |
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Notes |
WOS:000727698500001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5039 |
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Permanent link to this record |
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Author |
Borsato, M. et al; Zurita, J.; Henry, L.; Jashal, B.K.; Oyanguren, A. |
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Title |
Unleashing the full power of LHCb to probe stealth new physics |
Type |
Journal Article |
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Year |
2022 |
Publication |
Reports on Progress in Physics |
Abbreviated Journal |
Rep. Prog. Phys. |
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Volume |
85 |
Issue |
2 |
Pages |
024201 - 45pp |
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Keywords |
LHCb; stealth physics; BSM physics; hidden sectors; long-lived particles; dark matter |
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Abstract |
In this paper, we describe the potential of the LHCb experiment to detect stealth physics. This refers to dynamics beyond the standard model that would elude searches that focus on energetic objects or precision measurements of known processes. Stealth signatures include long-lived particles and light resonances that are produced very rarely or together with overwhelming backgrounds. We will discuss why LHCb is equipped to discover this kind of physics at the Large Hadron Collider and provide examples of well-motivated theoretical models that can be probed with great detail at the experiment. |
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Address |
[Borsato, M.] Heidelberg Univ, Phys Inst, Heidelberg, Germany, Email: xabier.cid.vidal@cern.ch |
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Publisher |
IOP Publishing Ltd |
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Language |
English |
Summary Language |
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Series Editor |
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Series Volume |
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ISSN |
0034-4885 |
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Conference |
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Notes |
WOS:000762056700001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5151 |
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Permanent link to this record |
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Author |
AbdusSalam, S.S. et al; Eberhardt, O. |
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Title |
Simple and statistically sound recommendations for analysing physical theories |
Type |
Journal Article |
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Year |
2022 |
Publication |
Reports on Progress in Physics |
Abbreviated Journal |
Rep. Prog. Phys. |
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Volume |
85 |
Issue |
5 |
Pages |
052201 - 11pp |
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Keywords |
particle physics; statistics; methodology |
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Abstract |
Physical theories that depend on many parameters or are tested against data from many different experiments pose unique challenges to statistical inference. Many models in particle physics, astrophysics and cosmology fall into one or both of these categories. These issues are often sidestepped with statistically unsound ad hoc methods, involving intersection of parameter intervals estimated by multiple experiments, and random or grid sampling of model parameters. Whilst these methods are easy to apply, they exhibit pathologies even in low-dimensional parameter spaces, and quickly become problematic to use and interpret in higher dimensions. In this article we give clear guidance for going beyond these procedures, suggesting where possible simple methods for performing statistically sound inference, and recommendations of readily-available software tools and standards that can assist in doing so. Our aim is to provide any physicists lacking comprehensive statistical training with recommendations for reaching correct scientific conclusions, with only a modest increase in analysis burden. Our examples can be reproduced with the code publicly available at Zenodo. |
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Address |
[AbdusSalam, Shehu S.; Fowlie, Andrew] Shahid Beheshti Univ, Dept Phys, Tehran, Iran, Email: andrew.j.fowlie@njnu.edu.cn |
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Publisher |
IOP Publishing Ltd |
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English |
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ISSN |
0034-4885 |
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Conference |
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Notes |
WOS:000791574900001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
5221 |
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Permanent link to this record |
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Author |
Kogler, R.; Nachman, B.; Schmidt, A.; Asquith, L.; Winkels, E.; Campanelli, M.; Delitzsch, C.; Harris, P.; Hinzmann, A.; Kar, D.; McLean, C.; Pilot, J.; Takahashi, Y.; Tran, N.; Vernieri, C.; Vos, M. |
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Title |
Jet substructure at the Large Hadron Collider |
Type |
Journal Article |
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Year |
2019 |
Publication |
Reviews of Modern Physics |
Abbreviated Journal |
Rev. Mod. Phys. |
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Volume |
91 |
Issue |
4 |
Pages |
045003 - 44pp |
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Keywords |
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Abstract |
Jet substructure has emerged to play a central role at the Large Hadron Collider, where it has provided numerous innovative ways to search for new physics and to probe the standard model, particularly in extreme regions of phase space. This review focuses on the development and use of state-of-the-art jet substructure techniques by the ATLAS and CMS experiments. |
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Address |
[Kogler, Roman; Hinzmann, Andreas] Univ Hamburg, Hamburg, Germany, Email: roman.kogler@uni-hamburg.de; |
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Publisher |
Amer Physical Soc |
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English |
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ISSN |
0034-6861 |
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Conference |
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Notes |
WOS:000505698100001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
4238 |
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Permanent link to this record |
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Author |
de Azcarraga, J.A. |
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Title |
The new Spanish educational legislation: why public education will not improve |
Type |
Journal Article |
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Year |
2022 |
Publication |
Revista Española de Pedagogía |
Abbreviated Journal |
Rev. Esp. Pedagog. |
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Volume |
80 |
Issue |
281 |
Pages |
111-129 |
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Keywords |
Forthcoming Spanish educational legislation; primary school; secondary education; universities |
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Abstract |
This paper provides some reasons that explain, in the view of the author, why the present eagerness of the Spanish Educational Authorities to reform all levels of education, from primary school to the universities, will not improve the quality of the Spanish educational system. |
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Address |
[Adolfo de Azcarraga, Jose] Univ Valencia, Fis Teor, Valencia, Spain, Email: j.a.de.azcarraga@ific.uv.es |
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Publisher |
Univ Int Rioja-Unir |
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Language |
Spanish |
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ISSN |
0034-9461 |
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Conference |
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Notes |
WOS:000752024500007 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
5125 |
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Permanent link to this record |
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Author |
Garcilazo, H.; Valcarce, A.; Vijande, J. |
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Title |
Stable bound states of N's, Lambda's and Xi's |
Type |
Journal Article |
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Year |
2017 |
Publication |
Revista Mexicana de Fisica |
Abbreviated Journal |
Rev. Mex. Fis. |
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Volume |
63 |
Issue |
5 |
Pages |
411-422 |
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Keywords |
Baryon-Baryon interactions; Faddeev equations; variational approaches |
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Abstract |
We review our recent work about the stability of strange few-body systems containing N's, Lambda's, and Xi's. We make use of local central Yukawa-type Malfliet-Tjon interactions reproducing the low-energy parameters and phase shifts of the nucleon-nucleon system and the latest updates of the hyperon-nucleon and hyperon-hyperon ESCO8c Nijmegen potentials. We solve the three-and four-body bound-state problems by means of Faddeev equations and a generalized Gaussian variational method, respectively. The hypertriton, Lambda np(I)J(P) = (1/2)1/2(+), is bound by 144 keV; the recently discussed Lambda nn (I)J(P) = (1/2)1/2(+) system is unbound, as well as the Lambda Lambda nn (I)J(P) = (1)0(+) system, being just above threshold. Our results indicate that the Xi NN, Xi Xi N and Xi Xi NN systems with maximal isospin might be bound. |
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Address |
[Garcilazo, H.] Inst Politecn Nacl, Escuela Super Fis & Matemat, Edificio 9, Mexico City 07738, DF, Mexico, Email: humberto@esfm.ipn.mx; |
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Publisher |
Soc Mexicana Fisica |
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English |
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ISSN |
0035-001x |
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Notes |
WOS:000410015700003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3291 |
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Permanent link to this record |
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Author |
ANTARES Collaboration (Bhandari, S. et al); Barrios-Marti, J.; Coleiro, A.; Hernandez-Rey, J.J.; Illuminati, G.; Tönnis, C.; Zornoza, J.D.; Zuñiga, J. |
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Title |
The SUrvey for Pulsars and Extragalactic Radio Bursts – II. New FRB discoveries and their follow-up |
Type |
Journal Article |
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Year |
2018 |
Publication |
Monthly Notices of the Royal Astronomical Society |
Abbreviated Journal |
Mon. Not. Roy. Astron. Soc. |
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Volume |
475 |
Issue |
2 |
Pages |
1427-1446 |
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Keywords |
radiation mechanisms: general; methods: data analysis; methods: observational; surveys; intergalactic medium; radio continuum: general |
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Abstract |
We report the discovery of four Fast Radio Bursts (FRBs) in the ongoing SUrvey for Pulsars and Extragalactic Radio Bursts at the Parkes Radio Telescope: FRBs 150610, 151206, 151230 and 160102. Our real-time discoveries have enabled us to conduct extensive, rapid multimessenger follow-up at 12 major facilities sensitive to radio, optical, X-ray, gamma-ray photons and neutrinos on time-scales ranging from an hour to a few months post-burst. No counterparts to the FRBs were found and we provide upper limits on afterglow luminosities. None of the FRBs were seen to repeat. Formal fits to all FRBs show hints of scattering while their intrinsic widths are unresolved in time. FRB 151206 is at low Galactic latitude, FRB 151230 shows a sharp spectral cut-off, and FRB 160102 has the highest dispersion measure (DM = 2596.1 +/- 0.3 pc cm(-3)) detected to date. Three of the FRBs have high dispersion measures (DM > 1500 pc cm(-3)), favouring a scenario where the DMis dominated by contributions from the intergalactic medium. The slope of the Parkes FRB source counts distribution with fluences > 2 Jy ms is alpha = – 2.2(-1.2)(+0.6) and still consistent with a Euclidean distribution (alpha = -3/2). We also find that the all-sky rate is 1.7(-0.9)(+1.5) x 10(3)FRBs/(4 pi sr)/day above similar to 2 Jy ms and there is currently no strong evidence for a latitude- dependent FRB sky rate. |
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Address |
[Bhandari, S.; Keane, E. F.; Barr, E. D.; Jameson, A.; Petroff, E.; Bailes, M.; Flynn, C.; Jankowski, F.; Krishnan, V. Venkatraman; Morello, V.; van Straten, W.; Andreoni, I.; Cooke, J.; Pritchard, T.] Swinburne Univ Technol, Ctr Astrophys & Supercomp, Mail H30,POB 218, Hawthorn, Vic 3122, Australia, Email: shivanibhandari58@gmail.com |
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Publisher |
Oxford Univ Press |
Place of Publication |
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English |
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ISSN |
0035-8711 |
ISBN |
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Notes |
WOS:000427345900001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
3518 |
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Permanent link to this record |