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Author Hueso-Gonzalez, F.; Ballester, F.; Perez-Calatayud, J.; Siebert, F.A.; Vijande, J.
Title Towards clinical application of RayStretch for heterogeneity corrections in LDR permanent I-125 prostate brachytherapy Type Journal Article
Year 2017 Publication Brachytherapy Abbreviated Journal Brachytherapy
Volume 16 Issue 3 Pages 616-623
Keywords Brachytherapy; Low-dose rate; Heterogeneities; Prostate; Calcifications; Dosimetry
Abstract PURPOSE: RayStretch is a simple algorithm proposed for heterogeneity corrections in low-dose-rate brachytherapy. It is built on top of TG-43 consensus data, and it has been validated with Monte Carlo (MC) simulations. In this study, we take a real clinical prostate implant with 71 1251 seeds as reference and we apply RayStretch to analyze its performance in worst-case scenarios. METHODS AND MATERIALS: To do so, we design two cases where large calcifications are located in the prostate lobules. RayStretch resilience under various calcification density values is also explored. Comparisons against MC calculations are performed. RESULTS: Dose volume histogram related parameters like prostate D-90, rectum D-2cc, or urethra D-10 obtained with RayStretch agree within a few percent with the detailed MC results for all cases considered. CONCLUSIONS: The robustness and compatibility of RayStretch with commercial treatment planning systems indicate its applicability in clinical practice for dosimetric corrections in prostate calcifications. Its use during intraoperative ultrasound planning is foreseen.
Address [Hueso-Gonzalez, Fernando] Target Systemelekt GmbH, Wuppertal, Germany, Email: javier.vijande@uv.es
Corporate Author Thesis
Publisher Elsevier Science Inc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 1538-4721 ISBN Medium
Area Expedition Conference
Notes WOS:000402231600019 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3151
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Author Zhao, X.; McLain, M.A.; Vijande, J.; Ferrando, A.; Carr, L.D.; Garcia-March, M.A.
Title Nonequilibrium quantum dynamics of partial symmetry breaking for ultracold bosons in an optical lattice ring trap Type Journal Article
Year 2019 Publication New Journal of Physics Abbreviated Journal New J. Phys.
Volume 21 Issue Pages 043042 - 13pp
Keywords partial symmetry breaking; ultracold boson; ring trap; nonequilibrium quantum dynamics
Abstract A vortex in a Bose-Einstein condensate on a ring undergoes quantum dynamics in response to a quantum quench in terms of partial symmetry breaking from a uniform lattice to a biperiodic one. Neither the current, a macroscopic measure, nor fidelity, a microscopic measure, exhibit critical behavior. Instead, the symmetry memory succeeds in identifying the critical symmetry breaking at which the system begins to forget its initial symmetry state. We further identify a symmetry energy difference in the low lying excited states which trends with the symmetry memory.
Address [Zhao, Xinxin] Peking Univ, Int Ctr Quantum Mat, Sch Phys, Beijing 100871, Peoples R China, Email: zhaoxinxin@pku.edu.cn;
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 1367-2630 ISBN Medium
Area Expedition Conference
Notes WOS:000465987600002 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 3995
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Author Oliver, S.; Vijande, J.; Tejedor-Aguilar, N.; Miro, R.; Rovira-Escutia, J.J.; Ballester, F.; Juste, B.; Carmona, V.; Felici, G.; Verdu, G.; Sanchis, E.; Conde, A.; Perez-Calatayud, J.
Title Monte Carlo flattening filter design to high energy intraoperative electron beam homogenization Type Journal Article
Year 2023 Publication Radiation Physics and Chemistry Abbreviated Journal Radiat. Phys. Chem.
Volume 212 Issue Pages 111102 - 6pp
Keywords Intraoperative radiotherapy; Electron portable LinAc; Flattening filter; Dosimetry; Monte Carlo
Abstract Intraoperative radiotherapy using mobile linear accelerators is used for a wide variety of malignancies. However, when large fields are used in combination with high energies, a deterioration of the flatness dose profile is measured with respect to smaller fields and lower energies. Indeed, for the LIAC HWL of Sordina, this deterioration is observed for the 12 MeV beam combined with 10 cm (or larger) diameter applicator. Aimed to solve this problem, a flattening filter has been designed and validated evaluating the feasibility of its usage at the upper part of the applicator. The design of the filter was based on Monte Carlo simulations because of its accuracy in modeling components of clinical devices, among other purposes. The LIAC 10 cm diameter applicator was modeled and simulated independently by two different research groups using two different MC codes, reproducing the heterogeneity of the 12 MeV energy beam. Then, an iterative process of filter design was carried out. Finally, the MC designed conical filter with the optimal size and height to obtain the desired flattened beam was built in-house using a 3D printer. During the experimental validation of the applicator-filter, percentage depth dose, beam profiles, absolute and peripheral dose measurements were performed to demonstrate the effectiveness of the filter addition in the applicator. These measurements conclude that the beam has been flattened, from 5.9% with the standard configuration to 1.6% for the configuration with the filter, without significant increase of the peripheral dose. Consequently, the new filter-applicator LIAC configuration can be used also in a conventional surgery room. A reduction of 16% of the output dose and a reduction of 1.1 mm in the D50 of the percentage depth dose was measured with respect to the original configuration. This work is a proof-of-concept that demonstrates that it is possible to add a filter able to flatten the beam delivered by the Sordina LIAC HWL. Future studies will focus on more refined technical solutions fully compatible with the integrity of the applicator, including its sterilization, to be safely introduced in the clinical practice.
Address [Oliver, S.; Miro, R.; Juste, B.; Verdu, G.] Univ Polite cn Vale ncia, Inst Segur Ind Radiofis & Medioambiental ISIRYM, Cami Vera S-N, Valencia 46022, Spain, Email: gverdu@iqn.upv.es
Corporate Author Thesis
Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0969-806x ISBN Medium
Area Expedition Conference
Notes WOS:001026194900001 Approved no
Is ISI yes International Collaboration yes
Call Number IFIC @ pastor @ Serial 5578
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Author Vijande, J.; Granero, D.; Perez-Calatayud, J.; Ballester, F.
Title Monte Carlo dosimetric study of the medium dose rate CSM40 source Type Journal Article
Year 2013 Publication Applied Radiation and Isotopes Abbreviated Journal Appl. Radiat. Isot.
Volume 82 Issue Pages 283-288
Keywords Brachytherapy; Cs-137 seed; TG-43 based dosimetry; Monte Carlo
Abstract The Cs-137 medium dose rate (MDR) CSM40 source model (Eckert & Ziegler BEBIG, Germany) is in clinical use but no dosimetric dataset has been published. This study aims to obtain dosimetric data for the CSM40 source for its use in clinical practice as required by the American Association of Physicists in Medicine (AAPM) and the European Society for Radiotherapy and Oncology (ESTRO). Penelope2008 and Geant4 Monte Carlo codes were used to characterize this source dosimetrically. It was located in an unbounded water phantom with composition and mass density as recommended by AAPM and ESTRO. Due to the low photon energies of Cs-137, absorbed dose was approximated by collisional kerma. Additional simulations were performed to obtain the air-kerma strength, sic. Mass-energy absorption coefficients in water and air were consistently derived and used to calculate collisional kerma. Results performed with both radiation transport codes showed agreement typically within 0.05%. Dose rate constant, radial dose function and anisotropy function are provided for the CSM40 and compared with published data for other commercially available Cs-137 sources. An uncertainty analysis has been performed. The data provided by this study can be used as input data and verification in the treatment planning systems. (C) 2013 Elsevier Ltd. All rights reserved.
Address [Vijande, J.; Ballester, F.] Univ Valencia, Dept Atom Mol & Nucl Phys, E-46100 Burjassot, Spain, Email: Javier.vijande@uv.es
Corporate Author Thesis
Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0969-8043 ISBN Medium
Area Expedition Conference
Notes WOS:000328804000043 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 1678
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Author Gimenez-Alventosa, V.; Ballester, F.; Vijande, J.
Title VoxelMages: a general-purpose graphical interface for designing geometries and processing DICOM images for PENELOPE Type Journal Article
Year 2016 Publication Applied Radiation And Isotopes Abbreviated Journal Appl. Radiat. Isot.
Volume 118 Issue Pages 251-257
Keywords 87.53.Bn; 87.53.Jw; 87.55.Qr; 87.55.km; 87.55.K
Abstract The design and construction of geometries for Monte Carlo calculations is an error-prone, time-consuming, and complex step in simulations describing particle interactions and transport in the field of medical physics. The software VoxelMages has been developed to help the user in this task. It allows to design complex geometries and to process DICOM image files for simulations with the general-purpose Monte Carlo code PENELOPE in an easy and straightforward way. VoxelMages also allows to import DICOM-RT structure contour information as delivered by a treatment planning system. Its main characteristics, usage and performance benchmarking are described in detail.
Address [Gimenez-Alventosa, V.; Ballester, F.; Vijande, J.] Univ Valencia, Dept Fis Atom Mol & Nucl, E-46100 Valencia, Spain
Corporate Author Thesis
Publisher Pergamon-Elsevier Science Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN (down) 0969-8043 ISBN Medium
Area Expedition Conference
Notes WOS:000390736100039 Approved no
Is ISI yes International Collaboration no
Call Number IFIC @ pastor @ Serial 2904
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