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Author |
Carrasco-Ribelles, L.A.; Pardo-Mas, J.R.; Tortajada, S.; Saez, C.; Valdivieso, B.; Garcia-Gomez, J.M. |
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Title |
Predicting morbidity by local similarities in multi-scale patient trajectories |
Type |
Journal Article |
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Year |
2021 |
Publication |
Journal of Biomedical Informatics |
Abbreviated Journal |
J. Biomed. Inform. |
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Volume |
120 |
Issue |
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Pages |
103837 - 9pp |
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Keywords |
Patient trajectory; Risk prediction; Local alignment; Dynamic programming; Diabetes; Cardiovascular disease |
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Abstract |
Patient Trajectories (PTs) are a method of representing the temporal evolution of patients. They can include information from different sources and be used in socio-medical or clinical domains. PTs have generally been used to generate and study the most common trajectories in, for instance, the development of a disease. On the other hand, healthcare predictive models generally rely on static snapshots of patient information. Only a few works about prediction in healthcare have been found that use PTs, and therefore benefit from their temporal dimension. All of them, however, have used PTs created from single-source information. Therefore, the use of longitudinal multi-scale data to build PTs and use them to obtain predictions about health conditions is yet to be explored. Our hypothesis is that local similarities on small chunks of PTs can identify similar patients concerning their future morbidities. The objectives of this work are (1) to develop a methodology to identify local similarities between PTs before the occurrence of morbidities to predict these on new query individuals; and (2) to validate this methodology on risk prediction of cardiovascular diseases (CVD) occurrence in patients with diabetes. We have proposed a novel formal definition of PTs based on sequences of longitudinal multi-scale data. Moreover, a dynamic programming methodology to identify local alignments on PTs for predicting future morbidities is proposed. Both the proposed methodology for PT definition and the alignment algorithm are generic to be applied on any clinical domain. We validated this solution for predicting CVD in patients with diabetes and we achieved a precision of 0.33, a recall of 0.72 and a specificity of 0.38. Therefore, the proposed solution in the diabetes use case can result of utmost utility to secondary screening. |
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Address |
[Carrasco-Ribelles, Lucia A.; Pardo-Mas, Jose Ramon; Saez, Carlos; Garcia-Gomez, Juan M.] Univ Politecn Valencia, Biomed Data Sci Lab BDSLAB, Inst Tecnol Informat & Comunicac ITACA, Camino Vera S-N, Valencia 46022, Spain, Email: lucarri@etsii.upv.es; |
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Publisher |
Academic Press Inc Elsevier Science |
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English |
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ISSN  |
1532-0464 |
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Notes |
WOS:000683527500003 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
4934 |
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Author |
Berenguer, A.; Coves, A.; Gimeno, B.; Bronchalo, E.; Boria, V.E. |
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Title |
Experimental Study of the Multipactor Effect in a Partially Dielectric-Loaded Rectangular Waveguide |
Type |
Journal Article |
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Year |
2019 |
Publication |
IEEE Microwave and Wireless Components Letters |
Abbreviated Journal |
IEEE Microw. Wirel. Compon. Lett. |
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Volume |
29 |
Issue |
9 |
Pages |
595-597 |
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Keywords |
Dielectric; multipactor effect; rectangular waveguide; RF breakdown; Secondary Electron Yield (SEY); waveguide transformer |
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Abstract |
This letter presents the experimental study of the multipactor threshold in a partially dielectric-loaded rectangular waveguide, whose results validate a multipactor model recently developed by the authors, which includes the charge distribution appearing on the dielectric surface during the multipactor discharge. First, the variation of the multipactor RF voltage threshold has been theoretically analyzed in different waveguide configurations: in an empty waveguide, and also in the cases of a one-sided and two-sided dielectric-loaded waveguides. To reach this aim, an in-house Monte Carlo simulation tool has been developed. The Secondary Electron Yield (SEY) of the metallic and dielectric materials used in the numerical simulations have been measured experimentally. Finally, an aluminum WR-75 symmetric E-plane rectangular waveguide transformer has been designed and fabricated, in which several multipaction tests have been carried out to validate the in-house software tool, demonstrating an excellent agreement between the simulation results and the experimental data. |
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Address |
[Berenguer, Andres; Coves, Angela; Bronchalo, Enrique] Univ Miguel Hernandez Elche, Dept Commun Engn, Elche 03202, Spain, Email: angela.coves@umh.es |
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Publisher |
Ieee-Inst Electrical Electronics Engineers Inc |
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English |
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ISSN |
1531-1309 |
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Conference |
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Notes |
WOS:000489754400009 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
4170 |
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Author |
Carbone, C.; Mena, O.; Verde, L. |
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Title |
Cosmological parameters degeneracies and non-Gaussian halo bias |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
07 |
Issue |
7 |
Pages |
020 - 17pp |
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Keywords |
power spectrum; redshift surveys; galaxy clusters; cosmological parameters from LSS |
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Abstract |
We study the impact of the cosmological parameters uncertainties on the measurements of primordial non-Gaussianity through the large-scale non-Gaussian halo bias effect. While this is not expected to be an issue for the standard Lambda CDM model, it may not be the case for more general models that modify the large-scale shape of the power spectrum. We consider the so-called local non-Gaussianity model, parametrized by the f(NL) non-Gaussianity parameter which is zero for a Gaussian case, and make forecasts on f(NL) from planned surveys, alone and combined with a Planck CMB prior. In particular, we consider EUCLID- and LSST-like surveys and forecast the correlations among f(NL) and the running of the spectral index alpha(s), the dark energy equation of state w, the effective sound speed of dark energy perturbations c(s)(2), the total mass of massive neutrinos M-nu = Sigma m(nu), and the number of extra relativistic degrees of freedom N-nu(rel). Neglecting CMB information on f(NL) and scales k > 0.03h/Mpc, we find that, if N-nu(rel) is assumed to be known, the uncertainty on cosmological parameters increases the error on f(NL) by 10 to 30% depending on the survey. Thus the f(NL) constraint is remarkable robust to cosmological model uncertainties. On the other hand, if N-nu(rel) is simultaneously constrained from the data, the f(NL) error increases by similar to 80%. Finally, future surveys which provide a large sample of galaxies or galaxy clusters over a volume comparable to the Hubble volume can measure primordial non-Gaussianity of the local form with a marginalized 1-sigma error of the order Delta f(NL) similar to 2 – 5, after combination with CMB priors for the remaining cosmological parameters. These results are competitive with CMB bispectrum constraints achievable with an ideal CMB experiment. |
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Address |
[Carbone, Carmelita] Univ Bologna, Dipartimento Astron, I-40127 Bologna, Italy, Email: carmelita.carbone@unibo.it |
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Publisher |
Iop Publishing Ltd |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000283573200010 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
347 |
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Author |
Wagner, C.; Verde, L.; Boubekeur, L. |
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Title |
N-body simulations with generic non-Gaussian initial conditions I: power spectrum and halo mass function |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
10 |
Issue |
10 |
Pages |
022 - 24pp |
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Keywords |
power spectrum; cosmological simulations; initial conditions and eternal universe; galaxy clusters |
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Abstract |
We address the issue of setting up generic non-Gaussian initial conditions for N-body simulations. We consider inflationary-motivated primordial non-Gaussianity where the perturbations in the Bardeen potential are given by a dominant Gaussian part plus a non-Gaussian part specified by its bispectrum. The approach we explore here is suitable for any bispectrum, i.e. it does not have to be of the so-called separable or factorizable form. The procedure of generating a non-Gaussian field with a given bispectrum (and a given power spectrum for the Gaussian component) is not univocal, and care must be taken so that higher-order corrections do not leave a too large signature on the power spectrum. This is so far a limiting factor of our approach. We then run N-body simulations for the most popular inflationary-motivated non-Gaussian shapes. The halo mass function and the non-linear power spectrum agree with theoretical analytical approximations proposed in the literature, even if they were so far developed and tested only for a particular shape (the local one). We plan to make the simulations outputs available to the community via the non-Gaussian simulations comparison project web site http://icc.ub.edu/similar to liciaverde/NGSCP.html. |
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Address |
[Wagner, Christian; Verde, Licia] Univ Barcelona, ICCUB IEEC, E-08028 Barcelona, Spain, Email: cwagner@icc.ub.edu |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000283577600013 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ elepoucu @ |
Serial |
339 |
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Author |
Jimenez, R.; Kitching, T.; Pena-Garay, C.; Verde, L. |
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Title |
Can we measure the neutrino mass hierarchy in the sky? |
Type |
Journal Article |
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Year |
2010 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
05 |
Issue |
5 |
Pages |
035 - 14pp |
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Keywords |
cosmological neutrinos; neutrino masses from cosmology; power spectrum; gravitational lensing |
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Abstract |
Cosmological probes are steadily reducing the total neutrino mass window, resulting in constraints on the neutrino-mass degeneracy as the most significant outcome. In this work we explore the discovery potential of cosmological probes to constrain the neutrino hierarchy, and point out some subtleties that could yield spurious claims of detection. This has an important implication for next generation of double beta decay experiments, that will be able to achieve a positive signal in the case of degenerate or inverted hierarchy of Majorana neutrinos. We find that cosmological experiments that nearly cover the whole sky could in principle distinguish the neutrino hierarchy by yielding 'substantial' evidence for one scenario over the another, via precise measurements of the shape of the matter power spectrum from large scale structure and weak gravitational lensing. |
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Address |
[Jimenez, Raul; Verde, Licia] Univ Barcelona, ICREA, E-08028 Barcelona, Spain, Email: raul.jimenez@icc.ub.edu |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
ISI:000279490800005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
418 |
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Author |
Agarwalla, S.K.; Blennow, M.; Fernandez-Martinez, E.; Mena, O. |
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Title |
Neutrino probes of the nature of light dark matter |
Type |
Journal Article |
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Year |
2011 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
09 |
Issue |
9 |
Pages |
004 - 19pp |
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Keywords |
dark matter experiments; neutrino detectors |
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Abstract |
Dark matter particles gravitationally trapped inside the Sun may annihilate into Standard Model particles, producing a flux of neutrinos. The prospects of detecting these neutrinos in future multi-kt neutrino detectors designed for other physics searches are explored here. We study the capabilities of a 34/100 kt liquid argon detector and a 100 kt magnetized iron calorimeter detector. These detectors are expected to determine the energy and the direction of the incoming neutrino with unprecedented precision allowing for tests of the dark matter nature at very low dark matter masses, in the range of 10-25 GeV. By suppressing the atmospheric background with angular cuts, these techniques would be sensitive to dark matter-nucleon spin-dependent cross sections at the fb level, reaching down to a few ab for the most favorable annihilation channels and detector technology. |
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Address |
[Agarwalla, Sanjib Kumar; Mena, Olga] Univ Politecn Valencia, CSIC, Inst Fis Corpuscular, E-46071 Valencia, Spain, Email: Sanjib.Agarwalla@ific.uv.es |
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Corporate Author |
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Thesis |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000296767000004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ elepoucu @ |
Serial |
858 |
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Author |
Bertone, G.; Cumberbatch, D.; Ruiz de Austri, R.; Trotta, R. |
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Title |
Dark Matter searches: the nightmare scenario |
Type |
Journal Article |
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Year |
2012 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
01 |
Issue |
1 |
Pages |
004 - 24pp |
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Keywords |
dark matter theory; dark matter experiments; neutrino detectors; solar and atmospheric neutrinos |
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Abstract |
The unfortunate case where the Large Hadron Collider (LHC) fails to discover physics Beyond the Standard Model (BSM) is sometimes referred to as the “Nightmare scenario” of particle physics. We study the consequences of this hypothetical scenario for Dark Matter (DM), in the framework of the constrained Minimal Supersymmetric Standard Model (cMSSM). We evaluate the surviving regions of the cMSSM parameter space after null searches at the LHC, using several different LHC configurations, and study the consequences for DM searches with ton-scale direct detectors and the IceCube neutrino telescope. We demonstrate that ton-scale direct detection experiments will be able to conclusively probe the cMSSM parameter space that would survive null searches at the LHC with 100 fb(-1) of integrated luminosity at 14TeV. We also demonstrate that IceCube (80 strings plus DeepCore) will be able to probe as much as similar or equal to 17% of the currently favoured parameter space after 5 years of observation. |
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Address |
[Bertone, Gianfranco] Univ Zurich, Inst Theoret Phys, CH-8057 Zurich, Switzerland, Email: bertone@iap.fr |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000300403300004 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
937 |
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Author |
Fornengo, N.; Lineros, R.A.; Regis, M.; Taoso, M. |
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Title |
Cosmological radio emission induced by WIMP Dark Matter |
Type |
Journal Article |
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Year |
2012 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
03 |
Issue |
3 |
Pages |
033 - 27pp |
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Keywords |
dark matter theory; power spectrum |
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Abstract |
We present a detailed analysis of the radio synchrotron emission induced by WIMP dark matter annihilations and decays in extragalactic halos. We compute intensity, angular correlation, and source counts and discuss the impact on the expected signals of dark matter clustering, as well as of other astrophysical uncertainties as magnetic fields and spatial diffusion. Bounds on dark matter microscopic properties are then derived, and, depending on the specific set of assumptions, they are competitive with constraints from other indirect dark matter searches. At GHz frequencies, dark matter sources can become a significant fraction of the total number of sources with brightness below the microJansky level. We show that, at this level of fluxes (which are within the reach of the next-generation radio surveys), properties of the faint edge of differential source counts, as well as angular correlation data, can become an important probe for WIMPs. |
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Address |
[Fornengo, N.; Regis, M.] Univ Turin, Dipartimento Fis Teor, I-10125 Turin, Italy, Email: fornengo@to.infn.it; |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000302949600033 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
999 |
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Author |
Herrero-Garcia, J.; Schwetz, T.; Zupan, J. |
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Title |
On the annual modulation signal in dark matter direct detection |
Type |
Journal Article |
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Year |
2012 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
03 |
Issue |
3 |
Pages |
005 - 28pp |
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Keywords |
dark matter theory; dark matter experiments; dark matter detectors |
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Abstract |
We derive constraints on the annual modulation signal in Dark Matter (DM) direct detection experiments in terms of the unmodulated event rate. A general bound independent of the details of the DM distribution follows from the assumption that the motion of the earth around the sun is the only source of time variation. The bound is valid for a very general class of particle physics models and also holds in the presence of an unknown unmodulated background. More stringent bounds are obtained, if modest assumptions on symmetry properties of the DM halo are adopted. We illustrate the bounds by applying them to the annual modulation signals reported by the DAMA and CoGeNT experiments in the framework of spin-independent elastic scattering. While the DAMA signal satisfies our bounds, severe restrictions on the DM mass can be set for CoGeNT. |
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Address |
[Herrero-Garcia, Juan; Schwetz, Thomas] Max Planck Inst Kernphys, D-69029 Heidelberg, Germany, Email: juan.a.herrero@uv.es; |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1475-7516 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000302949600005 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
1000 |
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Author |
de Putter, R.; Wagner, C.; Mena, O.; Verde, L.; Percival, W.J. |
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Title |
Thinking outside the box: effects of modes larger than the survey on matter power spectrum covariance |
Type |
Journal Article |
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Year |
2012 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
04 |
Issue |
4 |
Pages |
019 - 31pp |
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Keywords |
galaxy clustering; power spectrum; cosmological simulations; dark matter simulations |
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Abstract |
Accurate power spectrum (or correlation function) covariance matrices are a crucial requirement for cosmological parameter estimation from large scale structure surveys. In order to minimize reliance on computationally expensive mock catalogs, it is important to have a solid analytic understanding of the different components that make up a covariance matrix. Considering the matter power spectrum covariance matrix, it has recently been found that there is a potentially dominant effect on mildly non-linear scales due to power in modes of size equal to and larger than the survey volume. This beat coupling effect has been derived analytically in perturbation theory and while it has been tested with simulations, some questions remain unanswered. Moreover, there is an additional effect of these large modes, which has so far not been included in analytic studies, namely the effect on the estimated average density which enters the power spectrum estimate. In this article, we work out analytic, perturbation theory based expressions including both the beat coupling and this local average effect and we show that while, when isolated, beat coupling indeed causes large excess covariance in agreement with the literature, in a realistic scenario this is compensated almost entirely by the local average effect, leaving only similar to 10% of the excess. We test our analytic expressions by comparison to a suite of large N-body simulations, using both full simulation boxes and subboxes thereof to study cases without beat coupling, with beat coupling and with both beat coupling and the local average effect. For the variances, we find excellent agreement with the analytic expressions for k < 0.2 hMpc(-1) at z = 0.5, while the correlation coefficients agree to beyond k = 0.4 hMpc(-1). As expected, the range of agreement increases towards higher redshift and decreases slightly towards z = 0. We finish by including the large-mode effects in a full covariance matrix description for arbitrary survey geometry and confirming its validity using simulations. This may be useful as a stepping stone towards building an actual galaxy (or other tracer's) power spectrum covariance matrix. |
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Address |
[de Putter, Roland; Wagner, Christian; Verde, Lica] Univ Barcelona IEEC UB, ICC, Barcelona 08028, Spain, Email: rdeputter@berkeley.edu; |
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Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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English |
Summary Language |
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| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1475-7516 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
WOS:000303665000019 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
1016 |
|
| Permanent link to this record |
