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Author Alves, J.M.; Botella, F.J.; Branco, G.C.; Nebot, M. url  doi
openurl 
  Title Extending trinity to the scalar sector through discrete flavoured symmetries Type Journal Article
  Year 2020 Publication European Physical Journal C Abbreviated Journal Eur. Phys. J. C  
  Volume 80 Issue 8 Pages 710 - 14pp  
  Keywords  
  Abstract We conjecture the existence of a relation between elementary scalars and fermions, making it plausible the existence of three Higgs doublets. We introduce a Trinity Principle (TP) which, given the fact that there are no massless quarks, requires the existence of a minimum of three Higgs doublets. The TP states that each row of the mass matrix of a quark of a given charge should receive the contribution from one and only one scalar doublet and furthermore a given scalar doublet should contribute to one and only one row of the mass matrix of a quark of a given charge. This principle is analogous to the Natural Flavour Conservation (NFC) of Glashow and Weinberg with the key distinction that NFC required the introduction of a flavour blind symmetry, while the TP requires a flavoured symmetry, to be implemented in a natural way. We provide two examples which satisfy the Trinity Principle based on Z(3) and Z(2) x Z(2)' flavoured symmetries, and show that they are the minimal multi-Higgs extensions of the Standard Model where CP can be imposed as a symmetry of the full Lagrangian and broken by the vacuum, without requiring soft-breaking terms. We show that the vacuum phases are sufficient to generate a complex CKM matrix, in agreement with experiment. The above mentioned flavoured symmetries lead to a strong reduction in the number of parameters in the Yukawa interactions, enabling a control of the Scalar Flavour Changing Neutral Couplings (SFCNC). We analyse some of the other physical implications of the two models, including an estimate of the enhancement of the Baryon Asymmetry of the Universe provided by the new sources of CP violation, and a discussion of the strength of their tree-level SFCNC.  
  Address [Alves, Joao M.; Branco, Gustavo C.; Nebot, Miguel] Univ Lisboa UL, Inst Super Tecn IST, Dept Fis, Ave Rovisco Pais 1, P-1049001 Lisbon, Portugal, Email: j.magalhaes.alves@tecnico.ulisboa.pt;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 1434-6044 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000561119300002 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 4503  
Permanent link to this record
 

 
Author Alves, J.M.; Botella, F.J.; Branco, G.C.; Cornet-Gomez, F.; Nebot, M. url  doi
openurl 
  Title The framework for a common origin of delta(CKM) and delta S-PMN Type Journal Article
  Year 2021 Publication European Physical Journal C Abbreviated Journal Eur. Phys. J. C  
  Volume 81 Issue 8 Pages 727 - 11pp  
  Keywords  
  Abstract We analyse a possible connection between CP violations in the quark and lepton sectors, parametrised by the CKM and PMNS phases. If one assumes that CP breaking arises from complexYukawa couplings, both in the quark and lepton sectors, the above connection is not possible in general, sinceYukawa couplings in the two sectors have independent flavour structures. We show that both the CKM and PMNS phases can instead be generated by a vacuum phase in a class of two Higgs doublet models, and in this case a connection may be established. This scenario requires the presence of scalar FCNC at tree level, both in the quark and lepton sectors. The appearance of these FCNC is an obstacle and a blessing. An obstacle since one has to analyse which models are able to conform to the strict experimental limits on FCNC, both in the quark and lepton sectors. A blessing, because this class of models is falsifiable since FCNC arise at a level which can be probed experimentally in the near future, specially in the processes h up arrow e(+/-) t +/- and t -> hc. The connection between CP violations in CKM and PMNS is explicitely illustrated in models with Minimal Flavour Violation.  
  Address [Alves, Joao M.; Branco, Gustavo C.] Univ Lisbon, Inst Super Tecn, CFTP, Av Rovisco Pais 1, P-1049001 Lisbon, Portugal, Email: j.magalhaes.alves@tecnico.ulisboa.pt;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 1434-6044 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000685140600003 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 4938  
Permanent link to this record
 

 
Author Botella, F.J.; Cornet-Gomez, F.; Miro, C.; Nebot, M. url  doi
openurl 
  Title Muon and electron g-2 anomalies in a flavor conserving 2HDM with an oblique view on the CDF M-W value Type Journal Article
  Year 2022 Publication European Physical Journal C Abbreviated Journal Eur. Phys. J. C  
  Volume 82 Issue 10 Pages 915 - 25pp  
  Keywords  
  Abstract We consider a type I or type X two Higgs doublets model with a modified lepton sector. The generalized lepton sector is also flavor conserving but with the new Yukawa couplings completely decoupled from lepton mass proportionality. The model is one loop stable under renormalization group evolution and it allows to reproduce the g – 2 muon anomaly together with the different scenarios one can consider for the electron g – 2 anomaly, related to the Cesium and/or to the Rubidium recoilmeasurements of the fine structure constant. Thorough parameter space analyses are performed to constrain all the model parameters in the different scenarios, either including or not including the recent CDF measurement of the W boson mass. For light new scalars with masses in the 0.2-1.0 TeV range, the muon anomaly receives dominant one loop contributions; it is for heavy new scalars with masses above 1.2 TeV that two loop Barr-Zee diagrams are needed. The electron g-2 anomaly, if any, must always be obtained with the two loop contributions. The final allowed regions are quite sensitive to the assumptions about perturbativity of Yukawa couplings, which influence unexpected observables like the allowed scalar mass ranges. On that respect, intermediate scalar masses, highly constrained by direct LHC searches, are allowed provided that the new lepton Yukawa couplings are fully scrutinized, including values up to 250 GeV. In the framework of a complete model, fully numerically analysed, we show the implications of the recent M-W measurement.  
  Address [Botella, Francisco J.; Cornet-Gomez, Fernando; Miro, Carlos; Nebot, Miguel] Univ Valencia, Dept Fis Teor, CSIC, Burjassot 46100, Spain, Email: Francisco.J.Botella@uv.es;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 1434-6044 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000873885900002 Approved no  
  Is ISI yes International Collaboration yes  
  Call Number IFIC @ pastor @ Serial 5395  
Permanent link to this record
 

 
Author Alves, J.M.; Botella, F.J.; Miro, C.; Nebot, M. url  doi
openurl 
  Title Spontaneous CP violation and μ-τ symmetry intwo-Higgs-doublet models with flavour conservation Type Journal Article
  Year 2023 Publication European Physical Journal C Abbreviated Journal Eur. Phys. J. C  
  Volume 83 Issue 10 Pages 940 - 12pp  
  Keywords  
  Abstract In multi-Higgs-doublet models, requiring simultaneously that (i) CP violation only arises spontaneously, (ii)tree level scalar flavour changing couplings are absent and (iii) the fermion mixing matrix is CP violating, can only be achieved in a very specific manner. A general approach with new clarifying insights on the question is presented. Considering the quark sector, that peculiar possibility is not viable on phenomenological grounds. We show that, considering the lepton sector, it is highly interesting and leads to viable models with mu-tau symmetric PMNS matrices. Phenomenological implications of the models, both for Dirac and Majorana (in a type I seesaw scenario) neutrinos, are analysed.  
  Address [Miro, Carlos] Univ Valencia, Dept Fis Teor, CSIC, Valencia 46100, Spain, Email: j.magalhaes.alves@tecnico.ulisboa.pt;  
  Corporate Author Thesis  
  Publisher Springer Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 1434-6044 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001087967500002 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 5759  
Permanent link to this record
 

 
Author Sanjuan, R.; Nebot, M.; Peris, J.B.; Alcami, J. doi  openurl
  Title Immune Activation Promotes Evolutionary Conservation of T-Cell Epitopes in HIV-1 Type Journal Article
  Year 2013 Publication Plos Biology Abbreviated Journal PLoS. Biol.  
  Volume 11 Issue 4 Pages e1001523 - 10pp  
  Keywords  
  Abstract The immune system should constitute a strong selective pressure promoting viral genetic diversity and evolution. However, HIV shows lower sequence variability at T-cell epitopes than elsewhere in the genome, in contrast with other human RNA viruses. Here, we propose that epitope conservation is a consequence of the particular interactions established between HIV and the immune system. On one hand, epitope recognition triggers an anti-HIV response mediated by cytotoxic T-lymphocytes (CTLs), but on the other hand, activation of CD4(+) helper T lymphocytes (T-H cells) promotes HIV replication. Mathematical modeling of these opposite selective forces revealed that selection at the intrapatient level can promote either T-cell epitope conservation or escape. We predict greater conservation for epitopes contributing significantly to total immune activation levels (immunodominance), and when T-H cell infection is concomitant to epitope recognition (transinfection). We suggest that HIV-driven immune activation in the lymph nodes during the chronic stage of the disease may offer a favorable scenario for epitope conservation. Our results also support the view that some pathogens draw benefits from the immune response and suggest that vaccination strategies based on conserved T-H epitopes may be counterproductive.  
  Address Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolut, Valencia, Spain, Email: rafael.sanjuan@uv.es  
  Corporate Author Thesis  
  Publisher Public Library Science Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN (up) 1545-7885 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000318687800003 Approved no  
  Is ISI yes International Collaboration no  
  Call Number IFIC @ pastor @ Serial 1446  
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