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Roser, J., Barrientos, L., Bernabeu, J., Borja-Lloret, M., Muñoz, E., Ros, A., et al. (2022). Joint image reconstruction algorithm in Compton cameras. Phys. Med. Biol., 67(15), 155009–15pp.
Abstract: Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging.
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Borys, D. et al, & Brzezinski, K. (2022). ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging. Phys. Med. Biol., 67(22), 224002–15pp.
Abstract: Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022).
Keywords: proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging
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Borja-Lloret, M., Barrientos, L., Bernabeu, J., Lacasta, C., Muñoz, E., Ros, A., et al. (2023). Influence of the background in Compton camera images for proton therapy treatment monitoring. Phys. Med. Biol., 68(14), 144001–16pp.
Abstract: Objective. Background events are one of the most relevant contributions to image degradation in Compton camera imaging for hadron therapy treatment monitoring. A study of the background and its contribution to image degradation is important to define future strategies to reduce the background in the system. Approach. In this simulation study, the percentage of different kinds of events and their contribution to the reconstructed image in a two-layer Compton camera have been evaluated. To this end, GATE v8.2 simulations of a proton beam impinging on a PMMA phantom have been carried out, for different proton beam energies and at different beam intensities. Main results. For a simulated Compton camera made of Lanthanum (III) Bromide monolithic crystals, coincidences caused by neutrons arriving from the phantom are the most common type of background produced by secondary radiations in the Compton camera, causing between 13% and 33% of the detected coincidences, depending on the beam energy. Results also show that random coincidences are a significant cause of image degradation at high beam intensities, and their influence in the reconstructed images is studied for values of the time coincidence windows from 500 ps to 100 ns. Significance. Results indicate the timing capabilities required to retrieve the fall-off position with good precision. Still, the noise observed in the image when no randoms are considered make us consider further background rejection methods.
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Alekhin, S. et al, & Hernandez, P. (2016). A facility to search for hidden particles at the CERN SPS: the SHiP physics case. Rep. Prog. Phys., 79(12), 124201–137pp.
Abstract: This paper describes the physics case for a new fixed target facility at CERN SPS. The SHiP (search for hidden particles) experiment is intended to hunt for new physics in the largely unexplored domain of very weakly interacting particles with masses below the Fermi scale, inaccessible to the LHC experiments, and to study tau neutrino physics. The same proton beam setup can be used later to look for decays of tau-leptons with lepton flavour number non-conservation, tau -> 3 μand to search for weakly-interacting sub-GeV dark matter candidates. We discuss the evidence for physics beyond the standard model and describe interactions between new particles and four different portals-scalars, vectors, fermions or axion-like particles. We discuss motivations for different models, manifesting themselves via these interactions, and how they can be probed with the SHiP experiment and present several case studies. The prospects to search for relatively light SUSY and composite particles at SHiP are also discussed. We demonstrate that the SHiP experiment has a unique potential to discover new physics and can directly probe a number of solutions of beyond the standard model puzzles, such as neutrino masses, baryon asymmetry of the Universe, dark matter, and inflation.
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Curtin, D. et al, & Hirsch, M. (2019). Long-lived particles at the energy frontier: the MATHUSLA physics case. Rep. Prog. Phys., 82(11), 116201–133pp.
Abstract: We examine the theoretical motivations for long-lived particle (LLP) signals at the LHC in a comprehensive survey of standard model (SM) extensions. LLPs are a common prediction of a wide range of theories that address unsolved fundamental mysteries such as naturalness, dark matter, baryogenesis and neutrino masses, and represent a natural and generic possibility for physics beyond the SM (BSM). In most cases the LLP lifetime can be treated as a free parameter from the μm scale up to the Big Bang Nucleosynthesis limit of similar to 10(7) m. Neutral LLPs with lifetimes above similar to 100 m are particularly difficult to probe, as the sensitivity of the LHC main detectors is limited by challenging backgrounds, triggers, and small acceptances. MATHUSLA is a proposal for a minimally instrumented, large-volume surface detector near ATLAS or CMS. It would search for neutral LLPs produced in HL-LHC collisions by reconstructing displaced vertices (DVs) in a low-background environment, extending the sensitivity of the main detectors by orders of magnitude in the long-lifetime regime. We study the LLP physics opportunities afforded by a MATHUSLA-like detector at the HL-LHC, assuming backgrounds can be rejected as expected. We develop a model-independent approach to describe the sensitivity of MATHUSLA to BSM LLP signals, and compare it to DV and missing energy searches at ATLAS or CMS. We then explore the BSM motivations for LLPs in considerable detail, presenting a large number of new sensitivity studies. While our discussion is especially oriented towards the long-lifetime regime at MATHUSLA, this survey underlines the importance of a varied LLP search program at the LHC in general. By synthesizing these results into a general discussion of the top-down and bottom-up motivations for LLP searches, it is our aim to demonstrate the exceptional strength and breadth of the physics case for the construction of the MATHUSLA detector.
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Kasieczka, G. et al, & Sanz, V. (2021). The LHC Olympics 2020: a community challenge for anomaly detection in high energy physics. Rep. Prog. Phys., 84(12), 124201–64pp.
Abstract: A new paradigm for data-driven, model-agnostic new physics searches at colliders is emerging, and aims to leverage recent breakthroughs in anomaly detection and machine learning. In order to develop and benchmark new anomaly detection methods within this framework, it is essential to have standard datasets. To this end, we have created the LHC Olympics 2020, a community challenge accompanied by a set of simulated collider events. Participants in these Olympics have developed their methods using an R&D dataset and then tested them on black boxes: datasets with an unknown anomaly (or not). Methods made use of modern machine learning tools and were based on unsupervised learning (autoencoders, generative adversarial networks, normalizing flows), weakly supervised learning, and semi-supervised learning. This paper will review the LHC Olympics 2020 challenge, including an overview of the competition, a description of methods deployed in the competition, lessons learned from the experience, and implications for data analyses with future datasets as well as future colliders.
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de Azcarraga, J. A. (2022). The new Spanish educational legislation: why public education will not improve. Rev. Esp. Pedagog., 80(281), 111–129.
Abstract: This paper provides some reasons that explain, in the view of the author, why the present eagerness of the Spanish Educational Authorities to reform all levels of education, from primary school to the universities, will not improve the quality of the Spanish educational system.
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Garcilazo, H., Valcarce, A., & Vijande, J. (2017). Stable bound states of N's, Lambda's and Xi's. Rev. Mex. Fis., 63(5), 411–422.
Abstract: We review our recent work about the stability of strange few-body systems containing N's, Lambda's, and Xi's. We make use of local central Yukawa-type Malfliet-Tjon interactions reproducing the low-energy parameters and phase shifts of the nucleon-nucleon system and the latest updates of the hyperon-nucleon and hyperon-hyperon ESCO8c Nijmegen potentials. We solve the three-and four-body bound-state problems by means of Faddeev equations and a generalized Gaussian variational method, respectively. The hypertriton, Lambda np(I)J(P) = (1/2)1/2(+), is bound by 144 keV; the recently discussed Lambda nn (I)J(P) = (1/2)1/2(+) system is unbound, as well as the Lambda Lambda nn (I)J(P) = (1)0(+) system, being just above threshold. Our results indicate that the Xi NN, Xi Xi N and Xi Xi NN systems with maximal isospin might be bound.
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Reid, B. A. et al, & de Putter, R. (2012). The clustering of galaxies in the SDSS-III Baryon Oscillation Spectroscopic Survey: measurements of the growth of structure and expansion rate at z=0.57 from anisotropic clustering. Mon. Not. Roy. Astron. Soc., 426(4), 2719–2737.
Abstract: We analyse the anisotropic clustering of massive galaxies from the Sloan Digital Sky Survey III Baryon Oscillation Spectroscopic Survey (BOSS) Data Release 9 (DR9) sample, which consists of 264-283 galaxies in the redshift range 0.43 < z < 0.7 spanning 3275 deg(2). Both peculiar velocities and errors in the assumed redshiftdistance relation (AlcockPaczynski effect) generate correlations between clustering amplitude and orientation with respect to the line of sight. Together with the sharp baryon acoustic oscillation (BAO) standard ruler, our measurements of the broad-band shape of the monopole and quadrupole correlation functions simultaneously constrain the comoving angular diameter distance (2190 +/- 61 Mpc) to z = 0.57, the Hubble expansion rate at z = 0.57 (92.4 +/- 4.5 km s(-1) Mpc(-1)) and the growth rate of structure at that same redshift (d(sigma 8)/d ln a = 0.43 +/- 0.069). Our analysis provides the best current direct determination of both DA and H in galaxy clustering data using this technique. If we further assume a cold dark matter expansion history, our growth constraint tightens to d(sigma 8)/d ln a = 0.415 +/- 0.034. In combination with the cosmic microwave background, our measurements of D-A,H and d(sigma 8)/d ln a all separately require dark energy at z > 0.57, and when combined imply Omega(A) = 0.74 +/- 0.016, independent of the Universe's evolution at z < 0.57. All of these constraints assume scale-independent linear growth, and assume general relativity to compute both O(10 per cent) non-linear model corrections and our errors. In our companion paper, Samushia et al., we explore further cosmological implications of these observations.
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Anderson, L. et al, de Putter, R., & Mena, O. (2012). The clustering of galaxies in the SDSS-III Baryon Oscillation Spectroscopic Survey: baryon acoustic oscillations in the Data Release 9 spectroscopic galaxy sample. Mon. Not. Roy. Astron. Soc., 427(4), 3435–3467.
Abstract: We present measurements of galaxy clustering from the Baryon Oscillation Spectroscopic Survey (BOSS), which is part of the Sloan Digital Sky Survey III (SDSS-III). These use the Data Release 9 (DR9) CMASS sample, which contains 264 283 massive galaxies covering 3275 square degrees with an effective redshift z = 0.57 and redshift range 0.43 < z < 0.7. Assuming a concordance Lambda CDM cosmological model, this sample covers an effective volume of 2.2 Gpc(3), and represents the largest sample of the Universe ever surveyed at this density, (n) over bar approximate to 3 x 10(-4) h(-3) Mpc(3). We measure the angle-averaged galaxy correlation function and power spectrum, including density-field reconstruction of the baryon acoustic oscillation (BAO) feature. The acoustic features are detected at a significance of 5 sigma in both the correlation function and power spectrum. Combining with the SDSS-II luminous red galaxy sample, the detection significance increases to 6.7 sigma. Fitting for the position of the acoustic features measures the distance to z = 0.57 relative to the sound horizon D-V/r(s) = 13.67 +/ 0.22 at z = 0.57. Assuming a fiducial sound horizon of 153.19 Mpc, which matches cosmic microwave background constraints, this corresponds to a distance D-V (z = 0.57) = 2094 +/- 34 Mpc. At 1.7 per cent, this is the most precise distance constraint ever obtained from a galaxy survey. We place this result alongside previous BAO measurements in a cosmological distance ladder and find excellent agreement with the current supernova measurements. We use these distance measurements to constrain various cosmological models, finding continuing support for a flat Universe with a cosmological constant.
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