| |
Records |
Links |
|
Author |
NEMO-3 Collaboration (Argyriades, J. et al); Martin-Albo, J.; Novella, P. |
|
| |
Title |
Measurement of the two neutrino double beta decay half-life of Zr-96 with the NEMO-3 detector |
Type |
Journal Article |
| |
Year |
2010 |
Publication |
Nuclear Physics A |
Abbreviated Journal |
Nucl. Phys. A |
|
| |
Volume |
847 |
Issue |
3-4 |
Pages |
168-179 |
|
| |
Keywords |
RADIOACTIVITY Zr-96(2 beta); measured E-beta,E- E-gamma, beta beta-, beta gamma-coin; deduced T-1/2 for 2 nu beta beta-decay, NEMO-3 detector |
|
| |
Abstract |
Using 9.4 g of Zr-96 isotope and 1221 days of data from the NEMO-3 detector corresponding (0 0.031 kg y, the obtained 2 nu beta beta decay half-life measurement is T-1/2(2 nu) = [2.35 +/- 0.14(stat) +/- 0.16(syst)] x 10(19) yr. Different characteristics of the final state electrons have been studied, such as the energy sum, individual electron energy, and angular distribution. The 2v nuclear matrix element is extracted using the measured 2 nu beta beta half-life and is M-2 nu = 0.049 +/- 0.002. Constraints on 0 nu beta beta decay have also been set. |
|
| |
Address |
[Basharina-Freshville, A.; Chapon, A.; Daraktchieva, Z.; Flack, R.; Kauer, M.; King, S.; Saakyan, R.; Thomas, J.; Vasiliev, V.] UCL, London WC1E 6BT, England, Email: kauer@hep.ucl.ac.uk |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Elsevier Science Bv |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0375-9474 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000283955700003 |
Approved |
no |
|
| |
Is ISI  |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ elepoucu @ |
Serial |
337 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
CDF Collaboration (Aaltonen, T. et al); Cabrera, S. |
|
| |
Title |
Search for New Bottomlike Quark Pair Decays Q(Q)over-bar -> (tW +/-)((t)over-barW +/- in Same-Charge Dileption Events |
Type |
Journal Article |
| |
Year |
2010 |
Publication |
Physical Review Letters |
Abbreviated Journal |
Phys. Rev. Lett. |
|
| |
Volume |
104 |
Issue |
9 |
Pages |
091801 - 8pp |
|
| |
Keywords |
|
|
| |
Abstract |
We report the most restrictive direct limits on masses of fourth- generation down- type quarks b0, and quarklike composite fermions (B or T5= 3), decaying promptly to tW -/+. We search for a significant excess of events with two same- charge leptons (e, mu), several hadronic jets, and missing transverse energy. An analysis of data from pp collisions with an integrated luminosity of 2: 7 fb = 1 collected with the CDF II detector at Fermilab yields no evidence for such a signal, setting mass limits mb0, mB > 338 GeV= c2 and mT5= 3 > 365 GeV= c2 at 95% confidence level. |
|
| |
Address |
[Aaltonen, T.; Mehtala, P.; Orava, R.; Osterberg, K.; Saarikko, H.; van Remortel, N.] Univ Helsinki, Dept Phys, Div High Energy Phys, FIN-00014 Helsinki, Finland |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Amer Physical Soc |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0031-9007 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000275252500010 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
295 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Marco-Hernandez, R. |
|
| |
Title |
Development of a beam test telescope based on the Alibava readout system |
Type |
Journal Article |
| |
Year |
2011 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
|
| |
Volume |
6 |
Issue |
|
Pages |
C01002 - 7pp |
|
| |
Keywords |
Particle tracking detectors; Data acquisition circuits; Front-end electronics for detector readout; Digital electronic circuits |
|
| |
Abstract |
A telescope for a beam test have been developed as a result of a collaboration among the University of Liverpool, Centro Nacional de Microelectronica (CNM) of Barcelona and Instituto de Fisica Corpuscular (IFIC) of Valencia. This system is intended to carry out both analogue charge collection and spatial resolution measurements with different types of microstrip or pixel silicon detectors in a beam test environment. The telescope has four XY measurement as well as trigger planes (XYT board) and it can accommodate up to twelve devices under test (DUT board). The DUT board uses two Beetle ASICs for the readout of chilled silicon detectors. The board could operate in a self-triggering mode. The board features a temperature sensor and it can be mounted on a rotary stage. A peltier element is used for cooling the DUT. Each XYT board measures the track space points using two silicon strip detectors connected to two Beetle ASICs. It can also trigger on the particle tracks in the beam test. The board includes a CPLD which allows for the synchronization of the trigger signal to a common clock frequency, delaying and implementing coincidence with other XYT boards. An Alibava mother board is used to read out and to control each XYT/DUT board from a common trigger signal and a common clock signal. The Alibava board has a TDC on board to have a time stamp of each trigger. The data collected by each Alibava board is sent to a master card by means of a local data/address bus following a custom digital protocol. The master board distributes the trigger, clock and reset signals. It also merges the data streams from up to sixteen Alibava boards. The board has also a test channel for testing in a standard mode a XYT or DUT board. This board is implemented with a Xilinx development board and a custom patch board. The master board is connected with the DAQ software via 100M Ethernet. Track based alignment software has also been developed for the data obtained with the DAQ software. |
|
| |
Address |
[Marco-Hernandez, R.; Alibava Collaboration] CSIC UV, Inst Fis Corpuscular, E-46980 Paterna, Valencia, Spain, Email: rmarco@ific.uv.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Iop Publishing Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1748-0221 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000291345600007 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
no |
|
| |
Call Number |
IFIC @ elepoucu @ |
Serial |
644 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Linhart, V.; Burdette, D.; Chessi, E.; Cindro, V.; Clinthorne, N.H.; Cochran, E.; Grosicar, B.; Honscheid, K.; Kagan, H.; Lacasta, C.; Llosa, G.; Mikuz, M.; Stankova, V.; Studen, A.; Weilhammer, P.; Zontar, D. |
|
| |
Title |
Spectroscopy study of imaging devices based on silicon Pixel Array Detector coupled to VATAGP7 read-out chips |
Type |
Journal Article |
| |
Year |
2011 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
|
| |
Volume |
6 |
Issue |
|
Pages |
C01092 - 8pp |
|
| |
Keywords |
Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA); Compton imaging |
|
| |
Abstract |
Spectroscopic and timing response studies have been conducted on a detector module consisting of a silicon Pixel Array Detector bonded on two VATAGP7 read-out chips manufactured by Gamma-Medica Ideas using laboratory gamma sources and the internal calibration facilities (the calibration system of the read-out chips). The performed tests have proven that the chips have (i) non-linear calibration curves which can be approximated by power functions, (ii) capability to measure the energy of photons with energy resolution better than 2 keV (exact range and resolution depend on experimental setup), (iii) the internal calibration facility which provides 6 out of 16 available internal calibration charges within our region of interest (spanning the Compton edge of 511 keV photons). The peaks induced by the internal calibration facility are suitable for a fit of the calibration curves. However, they are not suitable for measurements of equivalent noise charge because their full width at half maximum varies with their amplitude. These facts indicate that the VATAGP7 chips are useful and precise tools for a wide variety of spectroscopic devices. We have also explored time walk of the module and peaking time of the spectroscopy signals provided by the chips. We have observed that (iv) the time walk is caused partly by the peaking time of the signals provided by the fast shaper of the chips and partly by the timing uncertainty related to the varying position of the photon interaction, (v) the peaking time of the spectroscopy signals provided by the chips increases with increasing pulse height. |
|
| |
Address |
[Linhart, V.; Lacasta, C.; Llosa, G.; Stankova, V.] UVEG, CSIC, IFIC, Expt Phys Dept,Inst Fis Corpuscular, E-46071 Valencia, Spain, Email: Vladimir.Linhart@ific.uv.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Iop Publishing Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1748-0221 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000291345600097 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ elepoucu @ |
Serial |
645 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
ATLAS Collaboration (Aad, G. et al); Amoros, G.; Cabrera Urban, S.; Castillo Gimenez, V.; Costa, M.J.; Escobar, C.; Ferrer, A.; Fuster, J.; Garcia, C.; Gonzalez de la Hoz, S.; Hernandez Jimenez, Y.; Higon-Rodriguez, E.; Irles Quiles, A.; Kaci, M.; Lacasta, C.; Lacuesta, V.R.; Marti-Garcia, S.; Miñano, M.; Mitsou, V.A.; Moles-Valls, R.; Moreno Llacer, M.; Oliver Garcia, E.; Perez Garcia-Estañ, M.T.; Ros, E.; Salt, J.; Solans, C.A.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valladolid Gallego, E.; Valls Ferrer, J.A.; Villaplana Perez, M.; Vos, M.; Wildauer, A. |
|
| |
Title |
Search for pair production of first or second generation leptoquarks in proton-proton collisions at sqrt(s)=7 TeV using the ATLAS detector at the LHC |
Type |
Journal Article |
| |
Year |
2011 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
|
| |
Volume |
83 |
Issue |
11 |
Pages |
112006 - 24pp |
|
| |
Keywords |
|
|
| |
Abstract |
This paper describes searches for the pair production of first or second generation scalar leptoquarks using 35 pb(-1) of proton-proton collision data recorded by the ATLAS detector at root s = 7 TeV. Leptoquarks are searched in events with two oppositely-charged muons or electrons and at least two jets, and in events with one muon or electron, missing transverse momentum and at least two jets. After event selection, the observed yields are consistent with the predicted backgrounds. Leptoquark production is excluded at the 95% CL for masses M-LQ < 376 (319) GeV and M-LQ < 422 (362) GeV for first and second generation scalar leptoquarks, respectively, when assuming the branching fraction of a leptoquark to a charged lepton is equal to 1.0 (0.5). |
|
| |
Address |
[Aad, G.; Ahles, F.; Beckingham, M.; Bernhard, R.; Bitenc, U.; Bruneliere, R.; Caron, S.; Carpentieri, C.; Christov, A.; Dahlhoff, A.; Dietrich, J.; Eckert, S.; Fehling-Kaschek, M.; Flechl, M.; Glatzer, J.; Hartert, J.; Heldmann, M.; Herten, G.; Horner, S.; Jakobs, K.; Ketterer, C.; Kollefrath, M.; Kononov, A. I.; Kuehn, S.; Lai, S.; Landgraf, U.; Lohwasser, K.; Ludwig, I.; Ludwig, J.; Lumb, D.; Mahboubi, K.; Meinhardt, J.; Mohr, W.; Nilsen, H.; Parzefall, U.; Bueso, X. Portell; Rammensee, M.; Runge, K.; Rurikova, Z.; Schmidt, E.; Schumacher, M.; Siegert, F.; Stoerig, K.; Sundermann, J. E.; Temming, K. K.; Thoma, S.; Tobias, J.; Tsiskaridze, V.; Venturi, M.; Vivarelli, I.; von Radziewski, H.; Warsinsky, M.; Weiser, C.; Werner, M.; Wiik, L. A. M.; Winkelmann, S.; Xie, S.; Zimmermann, S.] Univ Freiburg, Fak Math & Phys, Freiburg, Germany |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Amer Physical Soc |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1550-7998 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000291658800002 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
648 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Pierre Auger Collaboration (Abreu, P. et al); Pastor, S. |
|
| |
Title |
The Pierre Auger Observatory scaler mode for the study of solar activity modulation of galactic cosmic rays |
Type |
Journal Article |
| |
Year |
2011 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
|
| |
Volume |
6 |
Issue |
|
Pages |
P01003 - 16pp |
|
| |
Keywords |
Cherenkov detectors; Large detector systems for particle and astroparticle physics; Particle detectors |
|
| |
Abstract |
Since data-taking began in January 2004, the Pierre Auger Observatory has been recording the count rates of low energy secondary cosmic ray particles for the self-calibration of the ground detectors of its surface detector array. After correcting for atmospheric effects, modulations of galactic cosmic rays due to solar activity and transient events are observed. Temporal variations related with the activity of the heliosphere can be determined with high accuracy due to the high total count rates. In this study, the available data are presented together with an analysis focused on the observation of Forbush decreases, where a strong correlation with neutron monitor data is found. |
|
| |
Address |
[Abreu, P.; Andringa, S.; Assis, P.; Brogueira, P.; Cazon, L.; Conceicao, R.; Goncalves, P.; Pimenta, M.; Santo, C. E.; Santos, E.; Tome, B.] LIP, P-1000 Lisbon, Portugal |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Iop Publishing Ltd |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1748-0221 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000291345600003 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
646 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
HADES Collaboration (Agakishiev, G. et al); Diaz, J.; Gil, A. |
|
| |
Title |
In-medium effects on K-0 mesons in relativistic heavy-ion collisions |
Type |
Journal Article |
| |
Year |
2010 |
Publication |
Physical Review C |
Abbreviated Journal |
Phys. Rev. C |
|
| |
Volume |
82 |
Issue |
4 |
Pages |
044907 - 9pp |
|
| |
Keywords |
|
|
| |
Abstract |
We present the transverse momentum spectra and rapidity distributions of pi(-) and K-S(0) in Ar + KCl reactions at a beam kinetic energy of 1.756 A GeV measured with the High Acceptance Di-Electron Spectrometer (HADES). The reconstructed K-S(0) sample is characterized by good event statistics for a wide range in momentum and rapidity. We compare the experimental pi(-) and K-S(0) distributions to predictions by the Isospin Quantum Molecular Dynamics (IQMD) model. The model calculations show that K-S(0) at low transverse momenta constitute a particularly well-suited tool to investigate the kaon in-medium potential. Our K-S(0) data suggest a strong repulsive in-medium K-0 potential of about 40 MeV strength. |
|
| |
Address |
[Agakishiev, G.; Destefanis, M.; Gilardi, C.; Kirschner, D.; Kuehn, W.; Lange, J. S.; Metag, V.; Mishra, D.; Pechenov, V.; Pechenova, O.; Cavalcanti, T. Perez; Spataro, S.; Spruck, B.] Univ Giessen, Inst Phys 2, D-35392 Giessen, Germany, Email: laura.fabbietti@ph.tum.de |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Amer Physical Soc |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0556-2813 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000283648400009 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ elepoucu @ |
Serial |
334 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
CDF Collaboration (Aaltonen, T. et al); Cabrera, S. |
|
| |
Title |
Measurement of the top quark mass in the dilepton channel using m(T2) at CDF |
Type |
Journal Article |
| |
Year |
2010 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
|
| |
Volume |
81 |
Issue |
3 |
Pages |
031102 - 9pp |
|
| |
Keywords |
|
|
| |
Abstract |
We present measurements of the top quark mass using m(T2), a variable related to the transverse mass in events with two missing particles. We use the template method applied to t (t) over bar dilepton events produced in p (p) over bar collisions at Fermilab's Tevatron Collider and collected by the CDF detector. From a data sample corresponding to an integrated luminosity of 3.4 fb(-1), we select 236 t (t) over bar candidate events. Using the m(T2) distribution, we measure the top quark mass to be M-top = 168.0(-4.0)(4.8)(stat) +/- 2.9(syst) GeV/c(2). By combining m(T2) with the reconstructed top quark mass distributions based on a neutrino weighting method, we measure M-top = 169.3 +/- 2.7(stat) +/- 3.2(syst) GeV/c(2). This is the first application of the m(T2) variable in a mass measurement at a hadron collider. |
|
| |
Address |
[Aaltonen, T.; Mehtala, P.; Orava, R.; Osterberg, K.; Saarikko, H.; van Remortel, N.] Univ Helsinki, Div High Energy Phys, Dept Phys, FIN-00014 Helsinki, Finland |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Amer Physical Soc |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1550-7998 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000275069000002 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ pastor @ |
Serial |
296 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Aguilar-Saavedra, J.A.; Bernabeu, J. |
|
| |
Title |
W polarisation beyond helicity fractions in top quark decays |
Type |
Journal Article |
| |
Year |
2010 |
Publication |
Nuclear Physics B |
Abbreviated Journal |
Nucl. Phys. B |
|
| |
Volume |
840 |
Issue |
1-2 |
Pages |
349-378 |
|
| |
Keywords |
|
|
| |
Abstract |
We calculate the density matrix for the decay of a polarised top quark into a polarised W boson and a massive 17 quark, for the most general Wth vertex arising from dimension-six gauge-invariant effective operators. We show that, in addition to the well-known W helicity fractions, for polarised top decays it is worth defining and studying the transverse and normal W polarisation fractions, that is, the W polarisation alone two directions orthogonal to its momentum. In particular, a rather simple forward-backward asymmetry in the normal direction is found to be very sensitive to complex phases in one of the Wth anomalous couplings. This asymmetry, which indicates a normal W polarisation, can be generated for example by a P-odd. T-odd transition electric dipole moment. We also investigate the angular distribution of decay products in the top quark rest frame, calculating the spin analysing powers for a general Wth vertex. Finally we show that, using a combined fit to top decay observables and the t W cross section, at LHC it will be possible to obtain model-independent measurements of all the (complex) Wth couplings as well as the single top polarisation. Implications for spin correlations in top pair production are also discussed. |
|
| |
Address |
[Aguilar-Saavedra, J. A.] Univ Granada, Dept Fis Teor & Cosmos, E-18071 Granada, Spain, Email: jaas@ugr.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Elsevier Science Bv |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0550-3213 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000281832900013 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ elepoucu @ |
Serial |
370 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Sanjuan, R.; Nebot, M.; Chirico, N.; Mansky, L.M.; Belshaw, R. |
|
| |
Title |
Viral Mutation Rates |
Type |
Journal Article |
| |
Year |
2010 |
Publication |
Journal of Virology |
Abbreviated Journal |
J. Virol. |
|
| |
Volume |
84 |
Issue |
19 |
Pages |
9733-9748 |
|
| |
Keywords |
|
|
| |
Abstract |
Accurate estimates of virus mutation rates are important to understand the evolution of the viruses and to combat them. However, methods of estimation are varied and often complex. Here, we critically review over 40 original studies and establish criteria to facilitate comparative analyses. The mutation rates of 23 viruses are presented as substitutions per nucleotide per cell infection (s/n/c) and corrected for selection bias where necessary, using a new statistical method. The resulting rates range from 10(-8) to 10(-6) s/n/c for DNA viruses and from 10(-6) to 10(-4) s/n/c for RNA viruses. Similar to what has been shown previously for DNA viruses, there appears to be a negative correlation between mutation rate and genome size among RNA viruses, but this result requires further experimental testing. Contrary to some suggestions, the mutation rate of retroviruses is not lower than that of other RNA viruses. We also show that nucleotide substitutions are on average four times more common than insertions/deletions (indels). Finally, we provide estimates of the mutation rate per nucleotide per strand copying, which tends to be lower than that per cell infection because some viruses undergo several rounds of copying per cell, particularly double-stranded DNA viruses. A regularly updated virus mutation rate data set will be available at www.uv.es/rsanjuan/virmut. |
|
| |
Address |
[Sanjuan, Rafael] Univ Valencia, Inst Cavanilles Biodiversitat & Biol Evolutiva, Dept Genet, Valencia 46980, Spain, Email: rafael.sanjuan@uv.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
Amer Soc Microbiology |
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0022-538x |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
ISI:000282641800008 |
Approved |
no |
|
| |
Is ISI |
yes |
International Collaboration |
yes |
|
| |
Call Number |
IFIC @ elepoucu @ |
Serial |
371 |
|
| Permanent link to this record |
