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Author |
Penas, J.; Alejo, A.; Bembibre, A.; Apiñaniz, J.I.; Garcia-Garcia, E.; Guerrero, C.; Henares, J.L.; Hernandez-Palmero, I.; Mendez, C.; Millan-Callado, M.A.; Puyuelo-Valdes, P.; Seimetz, M.; Benlliure, J. |
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Title |
Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source |
Type |
Journal Article |
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Year |
2024 |
Publication |
Scientific Reports |
Abbreviated Journal |
Sci Rep |
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Volume |
14 |
Issue |
1 |
Pages |
11448 - 12pp |
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Abstract |
Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range. |
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Address |
[Penas, Juan; Alejo, Aaron; Bembibre, Adrian; Benlliure, Jose] Univ Santiago de Compostela, Inst Galego Fis Altas Enerxias IGFAE, Santiago De Compostela 15782, Spain, Email: j.benlliure@usc.es |
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Publisher |
Nature Portfolio |
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English |
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ISSN |
2045-2322 |
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Notes |
WOS:001228252900017 |
Approved |
no |
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Is ISI  |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
6143 |
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Author |
Martinez-Mirave, P.; Tamborra, I.; Tortola, M. |
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Title |
The Sun and core-collapse supernovae are leading probes of the neutrino lifetime |
Type |
Journal Article |
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Year |
2024 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
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Volume |
05 |
Issue |
5 |
Pages |
002 - 39pp |
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Keywords |
neutrino properties; solar and atmospheric neutrinos; supernova neutrinos |
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Abstract |
The large distances travelled by neutrinos emitted from the Sun and core -collapse supernovae together with the characteristic energy of such neutrinos provide ideal conditions to probe their lifetime, when the decay products evade detection. We investigate the prospects of probing invisible neutrino decay capitalising on the detection of solar and supernova neutrinos as well as the diffuse supernova neutrino background (DSNB) in the next -generation neutrino observatories Hyper-Kamiokande, DUNE, JUNO, DARWIN, and RES-NOVA. We find that future solar neutrino data will be sensitive to values of the lifetime -to -mass ratio tau 1 /m 1 and tau 2 /m 2 of O(10 – 1 -10 – 2 ) s/eV. From a core -collapse supernova explosion at 10 kpc, lifetime -to -mass ratios of the three mass eigenstates of O(10 5 ) s/eV could be tested. After 20 years of data taking, the DSNB would extend the sensitivity reach of tau 1 /m 1 to 10 8 s/eV. These results promise an improvement of about 6-15 orders of magnitude on the values of the decay parameters with respect to existing limits. |
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Address |
[Martinez-Mirave, Pablo; Tamborra, Irene] Univ Copenhagen, Niels Bohr Inst, Niels Bohr Int Acad, Blegdamsvej 17, DK-2100 Copenhagen, Denmark, Email: pablo.mirave@nbi.ku.dk; |
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Publisher |
IOP Publishing Ltd |
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English |
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Edition |
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ISSN |
1475-7516 |
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Conference |
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Notes |
WOS:001217801000002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6144 |
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Author |
Gorkavenko, V.; Jashal, B.K.; Kholoimov, V.; Kyselov, Y.; Mendoza, D.; Ovchynnikov, M.; Oyanguren, A.; Svintozelskyi, V.; Zhuo, J.H. |
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Title |
LHCb potential to discover long-lived new physics particles with lifetimes above 100 ps |
Type |
Journal Article |
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Year |
2024 |
Publication |
European Physical Journal C |
Abbreviated Journal |
Eur. Phys. J. C |
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Volume |
84 |
Issue |
6 |
Pages |
608 - 15pp |
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Keywords |
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Abstract |
For years, it has been believed that the main LHC detectors can play only a limited role of a lifetime frontier experiment exploring the parameter space of long-lived particles (LLPs)-hypothetical particles with tiny couplings to the Standard Model. This paper demonstrates that the LHCb experiment may become a powerful lifetime frontier experiment if it uses the new Downstream algorithm reconstructing tracks that do not allow hits in the LHCb vertex tracker. In particular, for many LLP scenarios, LHCb may be as sensitive as the proposed experiments beyond the main LHC detectors for various LLP models, including heavy neutral leptons, dark scalars, dark photons, and axion-like particles. |
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Address |
[Gorkavenko, Volodymyr; Kholoimov, Valerii; Kyselov, Yehor; Svintozelskyi, Volodymyr] Taras Shevchenko Natl Univ Kyiv, Kiev, Ukraine, Email: gorkavol@gmail.com; |
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Publisher |
Springer |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1434-6044 |
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Conference |
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Notes |
WOS:001246005200001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6145 |
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Author |
Centelles Chulia, S.; Miranda, O.G.; Valle, J.W.F. |
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Title |
Leptonic neutral-current probes in a short-distance DUNE-like setup |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review D |
Abbreviated Journal |
Phys. Rev. D |
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Volume |
109 |
Issue |
11 |
Pages |
115007 - 12pp |
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Keywords |
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Abstract |
Precision measurements of neutrino -electron scattering may provide a viable way to test the nonminimal form of the charged and neutral current weak interactions within a hypothetical near -detector setup for the Deep Underground Neutrino Experiment (DUNE). Although low -statistics, these processes are clean and provide information complementing the results derived from oscillation studies. They could shed light on the scale of neutrino mass generation in low -scale seesaw schemes. |
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Address |
[Chulia, Salvador Centelles] Max Planck Inst Kernphys, Saupfercheckweg 1, D-69117 Heidelberg, Germany, Email: chulia@mpi-hd.mpg.de; |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
2470-0010 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001243878300001 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6146 |
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Author |
Das, B. et al; Algora, A. |
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Title |
Broken seniority symmetry in the semimagic proton mid-shell nucleus 95Rh |
Type |
Journal Article |
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Year |
2024 |
Publication |
Physical Review Research |
Abbreviated Journal |
Phys. Rev. Res. |
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Volume |
6 |
Issue |
2 |
Pages |
L022038 - 7pp |
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Keywords |
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Abstract |
Lifetime measurements of low-lying excited states in the semimagic ( N = 50) nucleus 95 Rh have been performed by means of the fast -timing technique. The experiment was carried out using gamma -ray detector arrays consisting of LaBr 3 (Ce) scintillators and germanium detectors integrated into the DESPEC experimental setup commissioned for the Facility for Antiproton and Ion Research ( FAIR ) Phase -0, Darmstadt, Germany. The excited states in 95 Rh were populated primarily via the /3 decays of 95 Pd nuclei, produced in the projectile fragmentation of a 850 MeV / nucleon 124 Xe beam impinging on a 4 g / cm 2 9 Be target. The deduced electromagnetic E2 transition strengths for the gamma -ray cascade within the multiplet structure depopulating from the isomeric I pi = 21 / 2 + state are found to exhibit strong deviations from predictions of standard shell model calculations which feature approximately conserved seniority symmetry. In particular, the observation of a strongly suppressed E2 strength for the 13 / 2 + -> 9 / 2 + ground state transition cannot be explained by calculations employing standard interactions. This remarkable result may require revision of the nucleon-nucleon interactions employed in state-of-the-art theoretical model calculations, and might also point to the need for including three-body forces in the Hamiltonian. |
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Address |
[Das, B.; Cederwall, B.; Qi, C.; Aktas, O.; Liotta, R.; Vasiljevic, J.] KTH Royal Inst Technol, S-10691 Stockholm, Sweden, Email: b.das@gsi.de; |
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Publisher |
Amer Physical Soc |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
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ISBN |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:001240855200002 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
yes |
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Call Number |
IFIC @ pastor @ |
Serial |
6147 |
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