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Author |
Soriano, A.; Gonzalez, A.; Orero, A.; Moliner, L.; Carles, M.; Sanchez, F.; Benlloch, J.M.; Correcher, C.; Carrilero, V.; Seimetz, M. |
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Title |
Attenuation correction without transmission scan for the MAMMI breast PET |
Type |
Journal Article |
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Year |
2011 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
648 |
Issue |
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Pages |
S75-S78 |
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Keywords |
Breast PET; Attenuation correction |
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Abstract |
Whole-body Positron Emission Tomography (PET) scanners are required in order to span large Fields of View (FOV). Therefore, reaching the sensitivity and spatial resolution required for early stage breast tumor detection is not straightforward. MAMMI is a dedicated breast PET scanner with a ring geometry designed to provide PET images with a spatial resolution as high as 1.5 mm, being able to detect small breast tumors ( < 1 cm). The patient lays down in prone position during the scan, thus making possible to image the whole breast, up to regions close to the base of the pectoral without the requirement of breast compression. Attenuation correction (AC) for PET data improves the image quality and the quantitative accuracy of radioactivity distribution determination. In dedicated, high resolution breast cancer scanners, this correction would enhance the proper diagnosis in early disease stages. In whole-body PET scanners, AC is usually taken into account with the use of transmission scans, either by external radioactive rod sources or by Computed Tomography (CT). This considerably increases the radiation dose administered to the patient and time needed for the exploration. In this work we propose a method for breast shape identification by means of PET image segmentation. The breast shape identification will be used for the determination of the AC. For the case of a specific breast PET scanner the procedure we propose should provide AC similar to that obtained by transmission scans as we take advantage of the breast anatomical simplicity. Experimental validation of the proposed approach with a dedicated breast PET prototype is also presented. The main advantage of this method is an important dose reduction since the transmission scan is not required. |
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Address |
[Soriano, A.; Orero, A.; Moliner, L.; Carles, M.; Sanchez, F.; Benlloch, J. M.] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Paterna, Spain, Email: soriano@ific.uv.es |
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Elsevier Science Bv |
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Language |
English |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Edition |
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ISSN |
0168-9002 |
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Conference |
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Notes |
WOS:000305376900021 |
Approved |
no |
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Is ISI |
yes |
International Collaboration  |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
1069 |
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Author |
Herrero, V.; Toledo, J.; Catala, J.M.; Esteve, R.; Gil, A.; Lorca, D.; Monzo, J.M.; Sanchis, F.; Verdugo, A. |
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Title |
Readout electronics for the SiPM tracking plane in the NEXT-1 prototype |
Type |
Journal Article |
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Year |
2012 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
695 |
Issue |
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Pages |
229-232 |
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Keywords |
Neutrino less double beta decay; Xenon gas TPC; SiPM readout; Front-end electronics; Gated integrator |
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Abstract |
NEXT is a new experiment to search for neutrinoless double beta decay using a 100 kg radio-pure high-pressure gaseous xenon TPC with electroluminescence readout. A large-scale prototype with a SiPM tracking plane has been built. The primary electron paths can be reconstructed from time-resolved measurements of the light that arrives to the SiPM plane. Our approach is to measure how many photons have reached each SiPM sensor each microsecond with a gated integrator. We have designed and tested a 16-channel front-end board that includes the analog paths and a digital section. Each analog path consists of three different stages: a transimpedance amplifier, a gated integrator and an offset and gain control stage. Measurements show good linearity and the ability to detect single photoelectrons. |
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Address |
[Herrero, V.; Toledo, J.; Catala, J. M.; Esteve, R.; Monzo, J. M.; Sanchis, F.] Univ Politecn Valencia, CIEMAT, Ctr Mixto, I3M, Valencia 46022, Spain, Email: jtoledo@eln.upv.es |
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Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
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Conference |
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Notes |
WOS:000311469900049 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
1237 |
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Author |
Gil, A.; Diaz, J.; Gomez-Cadenas, J.J.; Herrero, V.; Rodriguez, J.; Serra, L.; Toledo, J.; Esteve, R.; Monzo, J.M.; Monrabal, F.; Yahlali, N. |
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Title |
Front-end electronics for accurate energy measurement of double beta decays |
Type |
Journal Article |
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Year |
2012 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
695 |
Issue |
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Pages |
407-409 |
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Keywords |
Front-end electronics; Xenon gas TPC; Energy measurement; Electroluminiscence; Double-beta decay |
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Abstract |
NEXT, a double beta decay experiment that will operate in Canfranc Underground Laboratory (Spain), aims at measuring the neutrinoless double-beta decay of the 136Xe isotope using a TPC filled with enriched Xenon gas at high pressure operated in electroluminescence mode. One technological challenge of the experiment is to achieve resolution better than 1% in the energy measurement using a plane of UV sensitive photomultipliers readout with appropriate custom-made front-end electronics. The front-end is designed to be sensitive to the single photo-electron to detect the weak primary scintillation light produced in the chamber, and also to be able to cope with the electroluminescence signal (several hundred times higher and with a duration of microseconds). For efficient primary scintillation detection and precise energy measurement of the electroluminescent signals the front-end electronics features low noise and adequate amplification. The signal shaping provided allows the digitization of the signals at a frequency as low as 40 MHz. |
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Address |
[Gil, A.; Diaz, J.; Gomez-Cadenas, J. J.; Rodriguez, J.; Serra, L.; Monrabal, F.; Yahlali, N.] Inst Fis Corpuscular CSIC UV, Valencia 46071, Spain, Email: alejandro.gil@ific.uv.es |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
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Conference |
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Notes |
WOS:000311469900092 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
1238 |
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Author |
Llosa, G. |
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Title |
Recent developments in photodetection for medical applications |
Type |
Journal Article |
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Year |
2015 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
787 |
Issue |
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Pages |
353-357 |
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Keywords |
Detectors; Photodetectors; Medical applications; PET; SPECT; Hadron Therapy |
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Abstract |
The use of the most advanced technology in medical imaging results in the development of high performance detectors that can significantly improve the performance of the medical devices employed in hospitals. Scintillator crystals coupled to photodetectors remain to be essential detectors in terms of performance and cost for medical imaging applications in different imaging modalities. Recent advances in photodetectors result in an increase of the performance of the medical scanners. Solid state detectors can provide substantial performance improvement, but are more complex to integrate into clinical detectors due mainly to their higher cost. Solid state photodetectors (APDs, SiPMs) have made new detector concepts possible and have led to improvements in different imaging modalities. Recent advances in detectors for medical imaging are revised. |
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Address |
UVEG, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: gabriela.llosa@ific.uv.es |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Conference |
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Notes |
WOS:000354869900079 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2233 |
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Author |
Hernandez-Prieto, A.; Quintana, B.; Martin, S.; Domingo-Pardo, C. |
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Title |
Study of accuracy in the position determination with SALSA, a gamma-scanning system for the characterization of segmented HPGe detectors |
Type |
Journal Article |
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Year |
2016 |
Publication |
Nuclear Instruments & Methods in Physics Research A |
Abbreviated Journal |
Nucl. Instrum. Methods Phys. Res. A |
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Volume |
823 |
Issue |
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Pages |
98-106 |
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Keywords |
gamma-Camera; Virtual collimation; SAlamanca Lyso-based Scanning Array (SALSA); Segmented HPGe detectors |
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Abstract |
Accurate characterization of the electric response of segmented high-purity germanium (HPGe) detectors as a function of the interaction position is one of the current goals of the Nuclear Physics community seeking to perform gamma-ray tracking or even imaging with these detectors. For this purpose, scanning devices must be developed to achieve the signal-position association with the highest precision. With a view to studying the accuracy achieved with SALSA, the SAlamanca Lyso-based Scanning Array, here we report a detailed study on the uncertainty sources and their effect in the position determination inside the HPGe detector to be scanned. The optimization performed on the design of SALSA, aimed at minimizing the effect of the uncertainty sources, afforded an intrinsic uncertainty of 2 mm for large coaxial detectors and 1 mm for planar ones. |
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Address |
[Hernandez-Prieto, A.; Quintana, B.; Martin, S.] Univ Salamanca, Dept Fis Fundamental, Lab Radiac Ionizantes, C Espejo S-N, E-37008 Salamanca, Spain, Email: alvaro.prieto@usal.es |
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Corporate Author |
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Thesis |
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Publisher |
Elsevier Science Bv |
Place of Publication |
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Editor |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0168-9002 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
WOS:000374661600014 |
Approved |
no |
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Is ISI |
yes |
International Collaboration |
no |
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Call Number |
IFIC @ pastor @ |
Serial |
2664 |
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| Permanent link to this record |
