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Author Ortiz Arciniega, J.L.; Carrio, F.; Valero, A. url  doi
openurl 
  Title FPGA implementation of a deep learning algorithm for real-time signal reconstruction in particle detectors under high pile-up conditions Type Journal Article
  Year 2019 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 14 Issue Pages P09002 - 13pp  
  Keywords Data processing methods; Pattern recognition; cluster finding; calibration and fitting methods; Simulation methods and programs  
  Abstract The analog signals generated in the read-out electronics of particle detectors are shaped prior to the digitization in order to improve the signal to noise ratio (SNR). The real amplitude of the analog signal is then obtained using digital filters, which provides information about the energy deposited in the detector. The classical digital filters have a good performance in ideal situations with Gaussian electronic noise and no pulse shape distortion. However, high-energy particle colliders, such as the Large Hadron Collider (LHC) at CERN, can produce multiple simultaneous events, which produce signal pileup. The performance of classical digital filters deteriorates in these conditions since the signal pulse shape gets distorted. In addition, this type of experiments produces a high rate of collisions, which requires high throughput data acquisitions systems. In order to cope with these harsh requirements, new read-out electronics systems are based on high-performance FPGAs, which permit the utilization of more advanced real-time signal reconstruction algorithms. In this paper, a deep learning method is proposed for real-time signal reconstruction in high pileup particle detectors. The performance of the new method has been studied using simulated data and the results are compared with a classical FIR filter method. In particular, the signals and FIR filter used in the ATLAS Tile Calorimeter are used as benchmark. The implementation, resources usage and performance of the proposed Neural Network algorithm in FPGA are also presented.  
  Address [Ortiz Arciniega, J. L.] Univ Valencia, Avinguda Univ S-N, Burjassot, Spain, Email: orarjo@alumni.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000486990000002 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 4150  
Permanent link to this record
 

 
Author Roser, J.; Muñoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J.F. doi  openurl
  Title Image reconstruction for a multi-layer Compton telescope: an analytical model for three interaction events Type Journal Article
  Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 65 Issue 14 Pages 145005 - 17pp  
  Keywords Compton camera; Compton imaging; hadron therapy; image reconstruction; lm-mlem; monte carlo simulations; multi-layer Compton telescope  
  Abstract Compton Cameras are electronically collimated photon imagers suitable for sub-MeV to few MeV gamma-ray detection. Such features are desirable to enablein vivorange verification in hadron therapy, through the detection of secondary Prompt Gammas. A major concern with this technique is the poor image quality obtained when the incoming gamma-ray energy is unknown. Compton Cameras with more than two detector planes (multi-layer Compton Cameras) have been proposed as a solution, given that these devices incorporate more signal sequences of interactions to the conventional two interaction events. In particular, three interaction events convey more spectral information as they allow inferring directly the incident gamma-ray energy. A three-layer Compton Telescope based on continuous Lanthanum (III) Bromide crystals coupled to Silicon Photomultipliers is being developed at the IRIS group of IFIC-Valencia. In a previous work we proposed a spectral reconstruction algorithm for two interaction events based on an analytical model for the formation of the signal. To fully exploit the capabilities of our prototype, we present here an extension of the model for three interaction events. Analytical expressions of the sensitivity and the System Matrix are derived and validated against Monte Carlo simulations. Implemented in a List Mode Maximum Likelihood Expectation Maximization algorithm, the proposed model allows us to obtain four-dimensional (energy and position) images by using exclusively three interaction events. We are able to recover the correct spectrum and spatial distribution of gamma-ray sources when ideal data are employed. However, the uncertainties associated to experimental measurements result in a degradation when real data from complex structures are employed. Incorrect estimation of the incident gamma-ray interaction positions, and missing deposited energy associated with escaping secondaries, have been identified as the causes of such degradation by means of a detailed Monte Carlo study. As expected, our current experimental resolution and efficiency to three interaction events prevents us from correctly recovering complex structures of radioactive sources. However, given the better spectral information conveyed by three interaction events, we expect an improvement of the image quality of conventional Compton imaging when including such events. In this regard, future development includes the incorporation of the model assessed in this work to the two interaction events model in order to allow using simultaneously two and three interaction events in the image reconstruction.  
  Address [Roser, J.; Munoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J. F.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: Jorge.Roser@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000552701600001 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 4481  
Permanent link to this record
 

 
Author Gimenez-Alventosa, V.; Gimenez, V.; Oliver, S. doi  openurl
  Title PenRed: An extensible and parallel Monte-Carlo framework for radiation transport based on PENELOPE Type Journal Article
  Year 2021 Publication Computer Physics Communications Abbreviated Journal Comput. Phys. Commun.  
  Volume 267 Issue Pages 108065 - 12pp  
  Keywords Radiation transport; Monte Carlo simulation; Electron-photon showers; Parallel computing; MPI; Medical physics  
  Abstract Monte Carlo methods provide detailed and accurate results for radiation transport simulations. Unfortunately, the high computational cost of these methods limits its usage in real-time applications. Moreover, existing computer codes do not provide a methodology for adapting these kinds of simulations to specific problems without advanced knowledge of the corresponding code system, and this restricts their applicability. To help solve these current limitations, we present PenRed, a general-purpose, standalone, extensible and modular framework code based on PENELOPE for parallel Monte Carlo simulations of electron-photon transport through matter. It has been implemented in C++ programming language and takes advantage of modern object-oriented technologies. In addition, PenRed offers the capability to read and process DICOM images as well as to construct and simulate image-based voxelized geometries, so as to facilitate its usage in medical applications. Our framework has been successfully verified against the original PENELOPE Fortran code. Furthermore, the implemented parallelism has been tested showing a significant improvement in the simulation time without any loss in precision of results. Program summary Program title: PenRed: Parallel Engine for Radiation Energy Deposition. CPC Library link to program files: https://doi .org /10 .17632/rkw6tvtngy.1 Licensing provision: GNU Affero General Public License (AGPL). Programming language: C++ standard 2011. Nature of problem: Monte Carlo simulations usually require a huge amount of computation time to achieve low statistical uncertainties. In addition, many applications necessitate particular characteristics or the extraction of specific quantities from the simulation. However, most available Monte Carlo codes do not provide an efficient parallel and truly modular structure which allows users to easily customise their code to suit their needs without an in-depth knowledge of the code system. Solution method: PenRed is a fully parallel, modular and customizable framework for Monte Carlo simulations of the passage of radiation through matter. It is based on the PENELOPE [1] code system, from which inherits its unique physics models and tracking algorithms for charged particles. PenRed has been coded in C++ following an object-oriented programming paradigm restricted to the C++11 standard. Our engine implements parallelism via a double approach: on the one hand, by using standard C++ threads for shared memory, improving the access and usage of the memory, and, on the other hand, via the MPI standard for distributed memory infrastructures. Notice that both kinds of parallelism can be combined together in the same simulation. Moreover, both threads and MPI processes, can be balanced using the builtin load balance system (RUPER-LB [30]) to maximise the performance on heterogeneous infrastructures. In addition, PenRed provides a modular structure with methods designed to easily extend its functionality. Thus, users can create their own independent modules to adapt our engine to their needs without changing the original modules. Furthermore, user extensions will take advantage of the builtin parallelism without any extra effort or knowledge of parallel programming. Additional comments including restrictions and unusual features: PenRed has been compiled in linux systems withg++ of GCC versions 4.8.5, 7.3.1, 8.3.1 and 9; clang version 3.4.2 and intel C++ compiler (icc) version 19.0.5.281. Since it is a C++11-standard compliant code, PenRed should be able to compile with any compiler with C++11 support. In addition, if the code is compiled without MPI support, it does not require any non standard library. To enable MPI capabilities, the user needs to install whatever available MPI implementation, such as openMPI [24] or mpich [25], which can be found in the repositories of any linux distribution. Finally, to provide DICOM processing support, PenRed can be optionally compiled using the dicom toolkit (dcmtk) [32] library. Thus, PenRed has only two optional dependencies, an MPI implementation and the dcmtk library.  
  Address [Gimenez-Alventosa, V] Univ Politecn Valencia, Inst Instrumentac Imagen Mol I3M, Ctr Mixto CSIC, Cami Vera S-N, Valencia 46022, Spain, Email: vicent.gimenez@i3m.upv.es;  
  Corporate Author Thesis  
  Publisher Elsevier Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0010-4655 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000678508900001 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 4907  
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Author Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Muñoz, E.; Ros, A.; Viegas, R.; Llosa, G. doi  openurl
  Title Joint image reconstruction algorithm in Compton cameras Type Journal Article
  Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 67 Issue 15 Pages 155009 - 15pp  
  Keywords Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope  
  Abstract Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging.  
  Address [Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Munoz, E.; Ros, A.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Jorge.Roser@ific.uv.es  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000827830200001 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 5298  
Permanent link to this record
 

 
Author Borys, D. et al; Brzezinski, K. doi  openurl
  Title ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging Type Journal Article
  Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 67 Issue 22 Pages 224002 - 15pp  
  Keywords proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging  
  Abstract Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022).  
  Address [Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl  
  Corporate Author Thesis  
  Publisher IOP Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000885248200001 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 5416  
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