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Author Brzezinski, K.; Oliver, J.F.; Gillam, J.; Rafecas, M. doi  openurl
  Title Study of a high-resolution PET system using a Silicon detector probe Type Journal Article
  Year 2014 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 59 Issue 20 Pages 6117-6140  
  Keywords PET; high-resolution imaging; Si detectors; PET insert  
  Abstract A high-resolution silicon detector probe, in coincidence with a conventional PET scanner, is expected to provide images of higher quality than those achievable using the scanner alone. Spatial resolution should improve due to the finer pixelization of the probe detector, while increased sensitivity in the probe vicinity is expected to decrease noise. A PET-probe prototype is being developed utilizing this principle. The system includes a probe consisting of ten layers of silicon detectors, each a 80 x 52 array of 1 x 1 x 1 mm(3) pixels, to be operated in coincidence with a modern clinical PET scanner. Detailed simulation studies of this system have been performed to assess the effect of the additional probe information on the quality of the reconstructed images. A grid of point sources was simulated to study the contribution of the probe to the system resolution at different locations over the field of view (FOV). A resolution phantom was used to demonstrate the effect on image resolution for two probe positions. A homogeneous source distribution with hot and cold regions was used to demonstrate that the localized improvement in resolution does not come at the expense of the overall quality of the image. Since the improvement is constrained to an area close to the probe, breast imaging is proposed as a potential application for the novel geometry. In this sense, a simplified breast phantom, adjacent to heart and torso compartments, was simulated and the effect of the probe on lesion detectability, through measurements of the local contrast recovery coefficient-to-noise ratio (CNR), was observed. The list-mode ML-EM algorithm was used for image reconstruction in all cases. As expected, the point spread function of the PET-probe system was found to be non-isotropic and vary with position, offering improvement in specific regions. Increase in resolution, of factors of up to 2, was observed in the region close to the probe. Images of the resolution phantom showed visible improvement in resolution when including the probe in the simulations. The image quality study demonstrated that contrast and spill-over ratio in other areas of the FOV were not sacrificed for this enhancement. The CNR study performed on the breast phantom indicates increased lesion detectability provided by the probe.  
  Address [Brzezinski, K.; Oliver, J. F.; Gillam, J.; Rafecas, M.] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46980 Valencia, Spain, Email: brzezinski@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000343092300011 Approved no  
  Is ISI yes International Collaboration (up) yes  
  Call Number IFIC @ pastor @ Serial 1963  
Permanent link to this record
 

 
Author Muñoz, E.; Barrio, J.; Etxebeste, A.; Ortega, P.G.; Lacasta, C.; Oliver, J.F.; Solaz, C.; Llosa, G. doi  openurl
  Title Performance evaluation of MACACO: a multilayer Compton camera Type Journal Article
  Year 2017 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.  
  Volume 62 Issue 18 Pages 7321-7341  
  Keywords Compton imaging; Compton camera; continuous LaBr3 crystal; silicon photomultiplier; hadron therapy  
  Abstract Compton imaging devices have been proposed and studied for a wide range of applications. We have developed a Compton camera prototype which can be operated with two or three detector layers based on monolithic lanthanum bromide (LaBr3) crystals coupled to silicon photomultipliers (SiPMs), to be used for proton range verification in hadron therapy. In this work, we present the results obtained with our prototype in laboratory tests with radioactive sources and in simulation studies. Images of a Na-22 and an Y-88 radioactive sources have been successfully reconstructed. The full width half maximum of the reconstructed images is below 4 mm for a Na-22 source at a distance of 5 cm.  
  Address [Munoz, Enrique; Barrio, John; Etxebeste, Ane; Ortega, Pablo G.; Lacasta, Carlos; Oliver, Josep F.; Solaz, Carles; Llosa, Gabriela] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0031-9155 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000408229900003 Approved no  
  Is ISI yes International Collaboration (up) yes  
  Call Number IFIC @ pastor @ Serial 3253  
Permanent link to this record
 

 
Author Doncel, M.; Cederwall, B.; Gadea, A.; Gerl, J.; Kojouharov, I.; Martin, S.; Palit, R.; Quintana, B. doi  openurl
  Title Performance and imaging capabilities of the DEGAS high-resolution gamma-ray detector array for the DESPEC experiment at FAIR Type Journal Article
  Year 2017 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 873 Issue Pages 36-38  
  Keywords Gamma spectroscopy; Imaging; Position-sensitive Ge detectors  
  Abstract Monte Carlo simulations of one of the possible configurations of the imaging phase for the DEGAS spectrometer situated at the DESPEC/NUSTAR experiment have been performed. The geometry consists of the coupling of the high-resolution gamma spectroscopy array, AGATA, with a high-resolution segmented planar detector utilized as an implantation detector in a compact configuration. The sensitivity and performance of the array in terms of efficiency and imaging capability is deduced.  
  Address [Doncel, M.] Univ Liverpool, Dept Phys, Oliver Lodge Lab, Liverpool, Merseyside, England, Email: doncel@liverpool.ac.uk  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000413823100008 Approved no  
  Is ISI yes International Collaboration (up) yes  
  Call Number IFIC @ pastor @ Serial 3349  
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Author NEXT Collaboration (Simon, A. et al); Gomez-Cadenas, J. J.; Alvarez, V.; Benlloch-Rodriguez, J. M.; Botas, A.; Carcel, S.; Carrion, J.V.; Diaz, J.; Felkai, R.; Ferrario, P.; Laing, A.; Liubarsky, I.; Lopez-March, N.; Martin-Albo, J.; Martinez, A.; Muñoz Vidal, J.; Musti, M.; Nebot-Guinot, M.; Novella, P.; Palmeiro, B.; Perez, J.; Querol, M.; Renner, J.; Rodriguez, J.; Sorel, M.; Torrent, J.; Yahlali, N. url  doi
openurl 
  Title Application and performance of an ML-EM algorithm in NEXT Type Journal Article
  Year 2017 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 12 Issue Pages P08009 - 22pp  
  Keywords Gaseous imaging and tracking detectors; Image reconstruction in medical imaging; Time projection Chambers (TPC); Medical-image reconstruction methods and algorithms; computer-aided software  
  Abstract The goal of the NEXT experiment is the observation of neutrinoless double beta decay in Xe-136 using a gaseous xenon TPC with electroluminescent amplification and specialized photodetector arrays for calorimetry and tracking. The NEXT Collaboration is exploring a number of reconstruction algorithms to exploit the full potential of the detector. This paper describes one of them: the Maximum Likelihood Expectation Maximization (ML-EM) method, a generic iterative algorithm to find maximum-likelihood estimates of parameters that has been applied to solve many different types of complex inverse problems. In particular, we discuss a bi-dimensional version of the method in which the photosensor signals integrated over time are used to reconstruct a transverse projection of the event. First results show that, when applied to detector simulation data, the algorithm achieves nearly optimal energy resolution (better than 0.5% FWHM at the Q value of 136Xe) for events distributed over the full active volume of the TPC.  
  Address [Simon, A.; Gomez-Cadenas, J. J.; Alvarez, V.; Benlloch-Rodriguez, J. M.; Botas, A.; Carcel, S.; Carrion, J. V.; Diaz, J.; Felkai, R.; Ferrario, P.; Laing, A.; Liubarsky, I.; Lopez-March, N.; Martin-Albo, J.; Martinez, A.; Munoz Vidal, J.; Musti, M.; Nebot-Guinot, M.; Novella, P.; Palmeiro, B.; Perez, J.; Querol, M.; Renner, J.; Rodriguez, J.; Sorel, M.; Torrent, J.; Yahlali, N.] CSIC, Inst Fis Corpuscular IFIC, Calle Catedrat Jose Beltran 2, Valencia 46980, Spain, Email: ander.simon@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000414159500009 Approved no  
  Is ISI yes International Collaboration (up) yes  
  Call Number IFIC @ pastor @ Serial 3358  
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Author Muñoz, E.; Barrio, J.; Bemmerer, D.; Etxebeste, A.; Fiedler, F.; Hueso-Gonzalez, F.; Lacasta, C.; Oliver, J.F.; Romer, K.; Solaz, C.; Wagner, L.; Llosa, G. doi  openurl
  Title Tests of MACACO Compton telescope with 4.44 MeV gamma rays Type Journal Article
  Year 2018 Publication Journal of Instrumentation Abbreviated Journal J. Instrum.  
  Volume 13 Issue Pages P05007 - 13pp  
  Keywords Compton imaging; Instrumentation for hadron therapy; Gamma detectors (scintillators, CZT, HPG, HgI etc); Photon detectors for UV, visible and IR photons (solid state) (PIN diodes, APDs, Si PMTs, G APDs, CCDs, EBCCDs, EMCCDs etc)  
  Abstract Hadron therapy offers the possibility of delivering a large amount of radiation dose to tumors with minimal absorption by the surrounding healthy tissue. In order to fully exploit the advantages of this technique, the use of real-time beam monitoring devices becomes mandatory. Compton imaging devices can be employed to map the distribution of prompt gamma emission during the treatment and thus assess its correct delivery. The Compton telescope prototype developed at IFIC-Valencia for this purpose is made of three layers of LaBr3 crystals coupled to silicon photomultipliers. The system has been tested in a 4.44 MeV gamma field at the 3 MV Tandetron accelerator at HZDR, Dresden. Images of the target with the system in three different positions separated by 10 mm were successfully reconstructed. This indicates the ability of MACACO for imaging the prompt gamma rays emitted at such energies.  
  Address [Munoz, E.; Barrio, J.; Etxebeste, A.; Lacasta, C.; Oliver, J. F.; Solaz, C.; Llosa, G.] Univ Valencia, CSIC, Inst Fis Corpuscular, Parque Cient,C Catedrat Jose Beltran 2, E-46980 Paterna, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es  
  Corporate Author Thesis  
  Publisher Iop Publishing Ltd Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1748-0221 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000431716900001 Approved no  
  Is ISI yes International Collaboration (up) yes  
  Call Number IFIC @ pastor @ Serial 3575  
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