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Author Assam, I.; Vijande, J.; Ballester, F.; Perez-Calatayud, J.; Poppe, B.; Siebert, F.A.
Title Evaluation of dosimetric effects of metallic artifact reduction and tissue assignment on Monte Carlo dose calculations for I-125 prostate implants Type Journal Article
Year 2022 Publication Medical Physics Abbreviated Journal Med. Phys.
Volume 49 Issue Pages 6195-6208
Keywords metallic artifact reduction; Monte Carlo dosimetry; post-implant CT; prostate brachytherapy; tissue assignment schemes; voxelized virtual patient model
Abstract Purpose Monte Carlo (MC) simulation studies, aimed at evaluating the magnitude of tissue heterogeneity in I-125 prostate permanent seed implant brachytherapy (BT), customarily use clinical post-implant CT images to generate a virtual representation of a realistic patient model (virtual patient model). Metallic artifact reduction (MAR) techniques and tissue assignment schemes (TAS) are implemented on the post-implant CT images to mollify metallic artifacts due to BT seeds and to assign tissue types to the voxels corresponding to the bright seed spots and streaking artifacts, respectively. The objective of this study is to assess the combined influence of MAR and TAS on MC absorbed dose calculations in post-implant CT-based phantoms. The virtual patient models used for I-125 prostate implant MC absorbed dose calculations in this study are derived from the CT images of an external radiotherapy prostate patient without BT seeds and prostatic calcifications, thus averting the need to implement MAR and TAS. Methods The geometry of the IsoSeed I25.S17plus source is validated by comparing the MC calculated results of the TG-43 parameters for the line source approximation with the TG-43U1S2 consensus data. Four MC absorbed dose calculations are performed in two virtual patient models using the egs_brachy MC code: (1) TG-43-based D-w,w-TG(43), (2) D-w,D-w-MBDC that accounts for interseed scattering and attenuation (ISA), (3) D-m,D-m that examines ISA and tissue heterogeneity by scoring absorbed dose in tissue, and (4) D-w,D-m that unlike D-m,D-m scores absorbed dose in water. The MC absorbed doses (1) and (2) are simulated in a TG-43 patient phantom derived by assigning the densities of every voxel to 1.00 g cm(-3) (water), whereas MC absorbed doses (3) and (4) are scored in the TG-186 patient phantom generated by mapping the mass density of each voxel to tissue according to a CT calibration curve. The MC absorbed doses calculated in this study are compared with VariSeed v8.0 calculated absorbed doses. To evaluate the dosimetric effect of MAR and TAS, the MC absorbed doses of this work (independent of MAR and TAS) are compared to the MC absorbed doses of different I-125 source models from previous studies that were calculated with different MC codes using post-implant CT-based phantoms generated by implementing MAR and TAS on post-implant CT images. Results The very good agreement of TG-43 parameters of this study and the published consensus data within 3% validates the geometry of the IsoSeed I25.S17plus source. For the clinical studies, the TG-43-based calculations show a D-90 overestimation of more than 4% compared to the more realistic MC methods due to ISA and tissue composition. The results of this work generally show few discrepancies with the post-implant CT-based dosimetry studies with respect to the D-90 absorbed dose metric parameter. These discrepancies are mainly Type B uncertainties due to the different I-125 source models and MC codes. Conclusions The implementation of MAR and TAS on post-implant CT images have no dosimetric effect on the I-125 prostate MC absorbed dose calculation in post-implant CT-based phantoms.
Address [Assam, Isong; Siebert, Frank-Andre] UKSH, Clin Radiotherapy Radiooncol, Campus Kiel, Kiel, Germany, Email: Isong.Assam@uksh.de
Corporate Author Thesis
Publisher Wiley Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0094-2405 ISBN Medium
Area Expedition Conference
Notes WOS:000835807200001 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 5321
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Author Fischer, O. et al; Pich, A.
Title Unveiling hidden physics at the LHC Type Journal Article
Year 2022 Publication European Physical Journal C Abbreviated Journal Eur. Phys. J. C
Volume 82 Issue 8 Pages 665 - 58pp
Keywords
Abstract The field of particle physics is at the crossroads. The discovery of a Higgs-like boson completed the Standard Model (SM), but the lacking observation of convincing resonances Beyond the SM (BSM) offers no guidance for the future of particle physics. On the other hand, the motivation for New Physics has not diminished and is, in fact, reinforced by several striking anomalous results in many experiments. Here we summarise the status of the most significant anomalies, including the most recent results for the flavour anomalies, the multi-lepton anomalies at the LHC, the Higgs-like excess at around 96 GeV, and anomalies in neutrino physics, astrophysics, cosmology, and cosmic rays. While the LHC promises up to 4 ab(-1) of integrated luminosity and far-reaching physics programmes to unveil BSM physics, we consider the possibility that the latter could be tested with present data, but that systemic shortcomings of the experiments and their search strategies may preclude their discovery for several reasons, including: final states consisting in soft particles only, associated production processes, QCD-like final states, close-by SM resonances, and SUSY scenarios where no missing energy is produced. New search strategies could help to unveil the hidden BSM signatures, devised by making use of the CERN open data as a new testing ground. We discuss the CERN open data with its policies, challenges, and potential usefulness for the community. We showcase the example of the CMS collaboration, which is the only collaboration regularly releasing some of its data. We find it important to stress that individuals using public data for their own research does not imply competition with experimental efforts, but rather provides unique opportunities to give guidance for further BSM searches by the collaborations. Wide access to open data is paramount to fully exploit the LHCs potential.
Address [Fischer, Oliver] Univ Liverpool, Dept Math Sci, Liverpool L69 7ZL, Merseyside, England, Email: oliver.fischer@liverpool.ac.uk
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1434-6044 ISBN Medium
Area Expedition Conference
Notes WOS:000835701100003 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 5322
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Author ATLAS Collaboration (Aad, G. et al); Amos, K.R.; Aparisi Pozo, J.A.; Bailey, A.J.; Cabrera Urban, S.; Cardillo, F.; Castillo Gimenez, V.; Costa, M.J.; Didenko,, M.; Escobar, C.; Estrada Pastor, O.; Fiorini, L.; Fullana Torregrosa, E.; Fuster, J.; Garcia, C.; Garcia Navarro, J.E.; Gonzalez de la Hoz, S.; Gonzalvo Rodriguez, G.R.; Guerrero Rojas, J.G.R.; Higon-Rodriguez, E.; Lacasta, C.; Lozano Bahilo, J.J.; Mamuzic, J.; Marti-Garcia, S.; Martinez Agullo, P.; Miralles Lopez, M.; Mitsou, V.A.; Monsonis Romero, L.; Moreno Llacer, M.; Navarro-Gonzalez, J.; Poveda, J.; Prades Ibañez, A.; Ruiz-Martinez, A.; Sabatini, P.; Salt, J.; Sanchez Sebastian, V.; Sayago Galvan, I.; Soldevila, U.; Sanchez, J.; Torro Pastor, E.; Valero, A.; Valls Ferrer, J.A.; Villaplana Perez, M.; Vos, M.
Title A search for an unexpected asymmetry in the production of e(+)mu(-) and e(-)mu(+) pairs in proton-proton collisions recorded by the ATLAS detector at root s=13 TeV Type Journal Article
Year 2022 Publication Physics Letters B Abbreviated Journal Phys. Lett. B
Volume 830 Issue Pages 137106 - 22pp
Keywords
Abstract This search, a type not previously performed at ATLAS, uses a comparison of the production cross sections for e(+)mu(-) and e(-)mu(+) pairs to constrain physics processes beyond the Standard Model. It uses 139 fb(-1) of proton-proton collision data recorded at root s = 13 TeV at the LHC. Targeting sources of new physics which prefer final states containing e(+)mu(-) and e(-)mu(+), the search contains two broad signal regions which are used to provide model-independent constraints on the ratio of cross sections at the 2% level. The search also has two special selections targeting supersymmetric models and leptoquark signatures. Observations using one of these selections are able to exclude, at 95% confidence level, singly produced smuons with masses up to 640 GeV in a model in which the only other light sparticle is a neutralino when the R-parity-violating coupling lambda(23)(1)' is close to unity. Observations using the other selection exclude scalar leptoquarks with masses below 1880 GeV when g(1R)(eu) = g(1R)(mu c) = 1, at 95% confidence level. The limit on the coupling reduces to g(1R)(eu) = g(1R)(mu c) = 0.46 for a mass of 1420 GeV.
Address [Jackson, P.; Kong, A. X. Y.; Potti, H.; Ruggeri, T. A.; Sharma, A. S.; White, M. J.] Univ Adelaide, Dept Phys, Adelaide, SA, Australia
Corporate Author Thesis
Publisher Elsevier Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0370-2693 ISBN Medium
Area Expedition Conference
Notes WOS:000833528800001 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 5324
Permanent link to this record
 

 
Author Villanueva-Domingo, P.; Villaescusa-Navarro, F.; Angles-Alcazar, D.; Genel, S.; Marinacci, F.; Spergel, D.N.; Hernquist, L.; Vogelsberger, M.; Dave, R.; Narayanan, D.
Title Inferring Halo Masses with Graph Neural Networks Type Journal Article
Year 2022 Publication Astrophysical Journal Abbreviated Journal Astrophys. J.
Volume 935 Issue 1 Pages 30 - 15pp
Keywords
Abstract Understanding the halo-galaxy connection is fundamental in order to improve our knowledge on the nature and properties of dark matter. In this work, we build a model that infers the mass of a halo given the positions, velocities, stellar masses, and radii of the galaxies it hosts. In order to capture information from correlations among galaxy properties and their phase space, we use Graph Neural Networks (GNNs), which are designed to work with irregular and sparse data. We train our models on galaxies from more than 2000 state-of-the-art simulations from the Cosmology and Astrophysics with MachinE Learning Simulations project. Our model, which accounts for cosmological and astrophysical uncertainties, is able to constrain the masses of the halos with a similar to 0.2 dex accuracy. Furthermore, a GNN trained on a suite of simulations is able to preserve part of its accuracy when tested on simulations run with a different code that utilizes a distinct subgrid physics model, showing the robustness of our method. The PyTorch Geometric implementation of the GNN is publicly available on GitHub (https://github.com/PabloVD/HaloGraphNet).
Address [Villanueva-Domingo, Pablo] Univ Valencia, Inst Fis Corpuscular IFIC, CSIC, E-46980 Paterna, Spain, Email: pablo.villanueva.domingo@gmail.com;
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0004-637x ISBN Medium
Area Expedition Conference
Notes WOS:000838320900001 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 5325
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Author MoEDAL Collaboration (Acharya, B. et al); Musumeci,E.; Mitsou, V.A.; Papavassiliou, J.; Ruiz de Austri, R.; Santra, A.; Vento, V.; Vives, O.
Title Search for highly-ionizing particles in pp collisions at the LHC's Run-1 using the prototype MoEDAL detector Type Journal Article
Year 2022 Publication European Physical Journal C Abbreviated Journal Eur. Phys. J. C
Volume 82 Issue 8 Pages 694 - 16pp
Keywords
Abstract A search for highly electrically charged objects (HECOs) and magnetic monopoles is presented using 2.2 fb(-1) of p – p collision data taken at a centre of mass energy (E-CM) of 8 TeV by the MoEDAL detector during LHC's Run-1. The data were collected using MoEDAL's prototype Nuclear Track Detectord array and the Trapping Detector array. The results are interpreted in terms of Drell-Yan pair production of stable HECO and monopole pairs with three spin hypotheses (0, 1/2 and 1). The search provides constraints on the direct production of magnetic monopoles carrying one to four Dirac magnetic charges and with mass limits ranging from 590 GeV/c(2) to 1 TeV/c(2). Additionally, mass limits are placed on HECOs with charge in the range 10e to 180e, where e is the charge of an electron, for masses between 30 GeV/c(2) and 1 TeV/c(2).
Address [Acharya, B.; Alexandre, J.; Ellis, J. R.; Fairbairn, M.; Mavromatos, N. E.; Sakellariadou, M.; Sarkar, S.] Kings Coll London, Phys Dept, Theoret Particle Phys & Cosmol Grp, London, England, Email: Laura.Patrizii@bo.infn.il;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1434-6044 ISBN Medium
Area Expedition Conference
Notes WOS:000838674800001 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 5326
Permanent link to this record