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Author Magan, D.L.P.; Caballero, L.; Domingo-Pardo, C.; Agramunt-Ros, J.; Albiol, F.; Casanovas, A.; Gonzalez, A.; Guerrero, C.; Lerendegui-Marco, J.; Tarifeño-Saldivia, A. url  doi
openurl 
  Title First tests of the applicability of gamma-ray imaging for background discrimination in time-of-flight neutron capture measurements Type Journal Article
  Year 2016 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 823 Issue Pages 107-119  
  Keywords Neutron capture cross-sections; gamma-ray imaging; Total energy detectors; Pulse-height weighting technique; Time-of-flight method  
  Abstract In this work we explore for the first time the applicability of using gamma-ray imaging in neutron capture measurements to identify and suppress spatially localized background. For this aim, a pinhole gamma camera is assembled, tested and characterized in terms of energy and spatial performance. It consists of a monolithic CeBr3 scintillating crystal coupled to a position-sensitive photomultiplier and readout through an integrated circuit AMIC2GR. The pinhole collimator is a massive carven block of lead. A series of dedicated measurements with calibrated sources and with a neutron beam incident on a Au-197 sample have been carried out at n_TOF, achieving an enhancement of a factor of two in the signal-to-background ratio when selecting only those events coming from the direction of the sample.  
  Address [Perez Magan, D. L.; Caballero, L.; Domingo-Pardo, C.; Agramunt-Ros, J.; Albiol, F.; Tarifeno-Saldivia, A.] Univ Valencia, CSIC, IFIC, E-46071 Valencia, Spain, Email: domingo@ific.uv.es  
  Corporate Author Thesis  
  Publisher Elsevier Science Bv Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000374661600015 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 2665  
Permanent link to this record
 

 
Author Balibrea-Correa, J.; Lerendegui-Marco, J.; Ladarescu, I.; Guerrero, C.; Rodriguez-Gonzalez, T.; Jimenez-Ramos, M.C.; Fernandez-Martinez, B.; Domingo-Pardo, C. url  doi
openurl 
  Title Hybrid in-beam PET- and Compton prompt-gamma imaging aimed at enhanced proton-range verification Type Journal Article
  Year 2022 Publication European Physical Journal Plus Abbreviated Journal Eur. Phys. J. Plus  
  Volume 137 Issue 11 Pages 1258 - 18pp  
  Keywords  
  Abstract We report on a hybrid in-beam PET and prompt-gamma Compton imaging system aimed at quasi real-time ion-range verification in proton-therapy treatments. Proof-of-concept experiments were carried out at the radiobiology beam line of the CNA cyclotron facility using a set of two synchronous Compton imagers and different target materials. The time structure of the 18 MeV proton beam was shaped with a series of beam-on and beam-off intervals, thereby mimicking a pulsed proton beam on a long time scale. During beam-on intervals, Compton imagingwas performed utilizing the high energy. -rays promptly emitted from the nuclear reactions occurring in the targets. In the course of the beam-off intervals in situ positron-emission tomography was accomplished with the same imagers using the beta+ decay of activated nuclei. The targets used were stacks of different materials covering also various proton ranges and energies. A systematic study on the performance of these two complementary imaging techniques is reported and the experimental results interpreted on the basis ofMonte Carlo calculations. The results demonstrate the possibility to combine both imaging techniques in a concomitant way, where high-efficiency prompt-gamma imaging is complemented with the high spatial accuracy of PET. Empowered by these results we suggest that a pulsed beam with a suitable duty cycle, in conjunction with in situ Compton- and PET-imaging may help to attain complementary information and quasi real-time range monitoring with high accuracy.  
  Address [Balibrea-Correa, J.; Lerendegui-Marco, J.; Ladarescu, I; Domingo-Pardo, C.] Univ Valencia, CSIC, Inst Fis Corpuscular, Valencia, Spain, Email: javier.balibrea@ific.uv.es  
  Corporate Author Thesis  
  Publisher Springer Heidelberg Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2190-5444 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000886327900002 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 5420  
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Author Mendoza, E.; Alcayne, V.; Cano-Ott, D.; Gonzalez-Romero, E.; Martinez, T.; de Rada, A.P.; Sanchez-Caballero, A.; Balibrea-Correa, J.; Domingo-Pardo, C.; Lerendegui-Marco, J.; Calvino, F.; Guerrero, C. doi  openurl
  Title Neutron capture measurements with high efficiency detectors and the Pulse Height Weighting Technique Type Journal Article
  Year 2023 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A  
  Volume 1047 Issue Pages 167894 - 16pp  
  Keywords Neutron capture; Total energy detector; Pulse height weighting technique; 7-ray cascades  
  Abstract Neutron capture cross section measurements in time-of-flight facilities are usually performed by detecting the prompt 7-rays emitted in the capture reactions. One of the difficulties to be addressed in these measurements is that the emitted 7-rays may change with the neutron energy, and therefore also the detection efficiency. To deal with this situation, many measurements use the so called Total Energy Detection (TED) technique, usually in combination with the Pulse Height Weighting Technique (PHWT). With it, it is sought that the detection efficiency depends only on the total energy of the 7-ray cascade, which does not vary much with the neutron energy. This technique was developed in the 1960s and has been used in many neutron capture experiments to date. One of the requirements of the technique is that 7-ray detectors have a low efficiency. This has meant that the PHWT has been used with experimental setups with low detection efficiencies. However, this condition does not have to be fulfilled by the experimental system as a whole. The main goal of this work is to show that it is possible to measure with a high efficiency detection system that uses the PHWT, and how to analyze the measured data.  
  Address [Mendoza, E.; Alcayne, V; Cano-Ott, D.; Gonzalez-Romero, E.; Martinez, T.; Perez de Rada, A.; Sanchez-Caballero, A.] Ctr Invest Energet Medioambientales & Tecnol CIEM, Madrid, Spain, Email: emilio.mendoza@ciemat.es  
  Corporate Author Thesis  
  Publisher Elsevier Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0168-9002 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:000908431800002 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 5468  
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Author Penas, J.; Alejo, A.; Bembibre, A.; Apiñaniz, J.I.; Garcia-Garcia, E.; Guerrero, C.; Henares, J.L.; Hernandez-Palmero, I.; Mendez, C.; Millan-Callado, M.A.; Puyuelo-Valdes, P.; Seimetz, M.; Benlliure, J. doi  openurl
  Title Production of carbon-11 for PET preclinical imaging using a high-repetition rate laser-driven proton source Type Journal Article
  Year 2024 Publication Scientific Reports Abbreviated Journal Sci Rep  
  Volume 14 Issue 1 Pages 11448 - 12pp  
  Keywords  
  Abstract Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.  
  Address [Penas, Juan; Alejo, Aaron; Bembibre, Adrian; Benlliure, Jose] Univ Santiago de Compostela, Inst Galego Fis Altas Enerxias IGFAE, Santiago De Compostela 15782, Spain, Email: j.benlliure@usc.es  
  Corporate Author Thesis  
  Publisher Nature Portfolio Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2045-2322 ISBN Medium  
  Area Expedition Conference  
  Notes WOS:001228252900017 Approved no  
  Is ISI yes International Collaboration (up) no  
  Call Number IFIC @ pastor @ Serial 6143  
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Author Colonna, N.; Belloni, F.; Berthoumieux, E.; Calviani, M.; Domingo-Pardo, C.; Guerrero, C.; Karadimos, D.; Lederer, C.; Massimi, C.; Paradela, C.; Plag, R.; Praena, J.; Sarmento, R. doi  openurl
  Title Advanced nuclear energy systems and the need of accurate nuclear data: the n_TOF project at CERN Type Journal Article
  Year 2010 Publication Energy & Environmental Science Abbreviated Journal Energy Environ. Sci.  
  Volume 3 Issue 12 Pages 1910-1917  
  Keywords  
  Abstract To satisfy the world's constantly increasing demand for energy, a suitable mix of different energy sources has to be devised. In this scenario, an important role could be played by nuclear energy, provided that major safety, waste and proliferation issues affecting current nuclear reactors are satisfactorily addressed. To this purpose, a large effort has been under way for a few years towards the development of advanced nuclear systems with the aim of closing the fuel cycle. Generation IV reactors, with full or partial waste recycling capability, accelerator driven systems, as well as new fuel cycles are the main options being investigated. The design of advanced systems requires improvements in basic nuclear data, such as cross-sections for neutron-induced reactions on actinides. In this paper, the main concepts of advanced reactor systems are described, together with the related needs of new and accurate nuclear data. The present activity in this field at the neutron facility n_TOF at CERN is discussed.  
  Address [Colonna, N.] Ist Nazl Fis Nucl, Sez Bari, I-70126 Bari, Italy, Email: nicola.colonna@ba.infn.it  
  Corporate Author Thesis  
  Publisher Royal Soc Chemistry Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1754-5692 ISBN Medium  
  Area Expedition Conference  
  Notes ISI:000284590900007 Approved no  
  Is ISI yes International Collaboration (up) yes  
  Call Number IFIC @ elepoucu @ Serial 319  
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