Abstract: The International Fusion Materials Irradiation Facility- DEMO Oriented Neutron Source (IFMIF-DONES) is a scientific infrastructure aimed to provide an intense neutron source for the qualification of materials to be used in future fusion power reactors. Its implementation is critical for the construction of the fusion DEMOnstration Power Plant (DEMO). IFMIF-DONES is a unique facility requiring a broad set of technologies. Although most of the necessary technologies have already been validated, there are still some aspects that introduce risks in the evolution of the project. In order to mitigate these risks, a consortium of companies, with the support of research centres and the funding of the CDTI (Centre for the Development of Industrial Technology and Innovation), has launched the DONES EVO Programme, which comprises six lines of research: center dot Improvement of signal transmission and integrity (planning and integration risks) center dot Optimisation of RF conditioning processes (planning and reliability risks) center dot Development of a reliable beam extraction device (reliability risks) center dot Development of technologies for the production of medical isotopes (reliability risks) center dot Improvement of critical parts of the lithium purification system (safety and reliability risks) center dot Validation of the manufacture of critical components with special materials (reliability risk). DONES EVO will focus on developing the appropriate response to the risks identified in the IFMIFDONES project through research and prototyping around the associated technologies.

Abstract: Urgent theoretical progress is needed in order to provide an estimate in the Standard Model of the recent measurement by LHCb of direct CP violation in charm-meson two-body decays. Rescattering effects must be taken into account for a meaningful theoretical description of the amplitudes involved in such category of observables, as signaled by the presence of large strong phases. We discuss the computation of the latter effects based on a two-channel coupled dispersion relation, which exploits isospin-zero phase shifts and inelasticity parametrizations of data coming from the rescattering processes ππ→ππ, πK→πK, and ππ→K¯K. The determination of the subtraction constants of the dispersive integrals relies on the leading contributions to the transition amplitudes from the 1/NC counting, where NC is the number of QCD colors. Furthermore, we use the measured values of the branching ratios to help in selecting the nonperturbative inputs in the isospin limit, from which we predict values for the CP asymmetries. We find that the predicted level of CP violation is much below the experimental value.

Abstract: Current cosmological tensions show that it is crucial to test the predictions from the canonical ACDM paradigm at different cosmic times. One very appealing test of structure formation in the Universe is the growth rate of structure in our universe f, usually parametrized via the growth index gamma, with f equivalent to Omega(m)(a)gamma and gamma similar or equal to 0.55 in the standard ACDM case. Recent studies have claimed a suppression of the growth of structure from a variety of cosmological observations, characterized by gamma > 0.55. By employing different self-consistent growth parametrizations schemes, we show here that gamma < 0.55, obtaining instead an enhanced growth of structure today. This preference reaches the 3 sigma significance using cosmic microwave background observations, supernova Ia and baryon acoustic oscillation measurements. The addition of cosmic microwave background lensing data relaxes such a preference to the 2 sigma level, since a larger lensing effect can always be compensated with a smaller structure growth, or, equivalently, with gamma > 0.55. We have also included the lensing amplitude AL as a free parameter in our data analysis, showing that the preference for AL > 1 still remains, except for some particular parametrizations when lensing observations are included. We also do not find any significant preference for an oscillatory dependence of AL, AL + Am sin l. To further reassess the effects of a nonstandard growth, we have computed by means of N-body simulations the dark matter density fields, the dark matter halo mass functions and the halo density profiles for different values of gamma. Future observations from the Square Kilometer Array, reducing by a factor of 3 the current errors on the gamma parameter, further confirm or refute with a strong statistical significance the deviation of the growth index from its standard value.

Abstract: Most advanced medical imaging techniques, such as positron-emission tomography (PET), require tracers that are produced in conventional particle accelerators. This paper focuses on the evaluation of a potential alternative technology based on laser-driven ion acceleration for the production of radioisotopes for PET imaging. We report for the first time the use of a high-repetition rate, ultra-intense laser system for the production of carbon-11 in multi-shot operation. Proton bunches with energies up to 10-14 MeV were systematically accelerated in long series at pulse rates between 0.1 and 1 Hz using a PW-class laser. These protons were used to activate a boron target via the 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} B(p,n) 11 \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$<^>{11}$$\end{document} C nuclear reaction. A peak activity of 234 kBq was obtained in multi-shot operation with laser pulses with an energy of 25 J. Significant carbon-11 production was also achieved for lower pulse energies. The experimental carbon-11 activities measured in this work are comparable to the levels required for preclinical PET, which would be feasible by operating at the repetition rate of current state-of-the-art technology (10 Hz). The scalability of next-generation laser-driven accelerators in terms of this parameter for sustained operation over time could increase these overall levels into the clinical PET range.

Abstract: The production of eta and eta' mesons is studied in proton -proton and proton -lead collisions collected with the LHCb detector. Proton -proton collisions are studied at center -of -mass energies of 5.02 and 13 TeV and proton -lead collisions are studied at a center -of -mass energy per nucleon of 8.16 TeV. The studies are performed in center -of -mass (c.m.) rapidity regions 2.5 < y(c.m.) < 3.5 (forward rapidity) and -4.0 < y(c.m.) < -3.0 (backward rapidity) defined relative to the proton beam direction. The eta and eta' production cross sections are measured differentially as a function of transverse momentum for 1.5 < p(T) < 10 GeV and 3 < p(T) < 10 GeV, respectively. The differential cross sections are used to calculate nuclear modification factors. The nuclear modification factors for eta and eta' mesons agree at both forward and backward rapidity, showing no significant evidence of mass dependence. The differential cross sections of eta mesons are also used to calculate eta/pi 0 cross-section ratios, which show evidence of a deviation from the world average. These studies offer new constraints on mass -dependent nuclear effects in heavy -ion collisions, as well as eta and eta' meson fragmentation.