| Records |
| Author |
Resta-Lopez, J. |
| Title |
Nonlinear protection of beam delivery systems for multi-TeV linear colliders |
Type |
Journal Article |
| Year |
2013 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
| Volume |
8 |
Issue |
|
Pages |
P11010 - 19pp |
| Keywords |
Beam Optics; Beam dynamics; Accelerator Subsystems and Technologies; Accelerator modelling and simulations (multi-particle dynamics; single-particle dynamics) |
| Abstract |
The post-linac energy collimation system of future e(+)e(-) multi-TeV linear colliders is designed to fulfil an essential function of protection of the Beam Delivery System (BDS) against miss-steered or errant beams likely generated by failure modes in the main linac. For the case of the Compact Linear Collider (CLIC), the energy collimators are required to withstand the impact of a full bunch train in case of failure. This condition makes the design of the energy collimation system especially challenging, if we take into account the need to dispose of an unprecedented transverse beam energy density per beam of the order of GJ/mm(2), when assuming the nominal CLIC beam parameters at 3 TeV centre-of-mass energy, which translates into an extremely high damage potential of uncontrolled beams. This leads to research activities involving new collimator materials and novel collimation techniques. The increase of the transverse spot size at the collimators using nonlinear magnets is a potential solution to guarantee the survival of the collimators. In this paper we present an alternative nonlinear optics based on a multipole magnet pair for energy collimation. In order to preserve an acceptable luminosity performance, we carefully study the general conditions for self-cancellation of optical aberrations between two multipoles. This nonlinear optics scheme is adapted to the requirements of the post-linac energy collimation system for the CLIC BDS, and its performance is investigated by means of beam tracking simulations. Although applied to the CLIC case, this nonlinear protection system could be adapted to other future colliders. |
| Address |
Univ Valencia, Inst Fis Corpuscular IFIC, Ctr Mixto CSIC, Inst Invest Paterna, Valencia 46071, Spain, Email: resta@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1748-0221 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000329193500035 |
Approved |
no |
| Is ISI |
yes |
International Collaboration  |
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| Call Number |
IFIC @ pastor @ |
Serial |
1697 |
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| Author |
Aguiar, P.; Rafecas, M.; Ortuño, J.E.; Kontaxakis, G.; Santos, A.; Pavia, J.; Rosetti, M. |
| Title |
Geometrical and Monte Carlo projectors in 3D PET reconstruction |
Type |
Journal Article |
| Year |
2010 |
Publication |
Medical Physics |
Abbreviated Journal |
Med. Phys. |
| Volume |
37 |
Issue |
11 |
Pages |
5691-5702 |
| Keywords |
3D PET; iterative reconstruction; list-mode reconstruction; ray-tracing techniques; Monte Carlo simulation; system response matrix |
| Abstract |
Purpose: In the present work, the authors compare geometrical and Monte Carlo projectors in detail. The geometrical projectors considered were the conventional geometrical Siddon ray-tracer (S-RT) and the orthogonal distance-based ray-tracer (OD-RT), based on computing the orthogonal distance from the center of image voxel to the line-of-response. A comparison of these geometrical projectors was performed using different point spread function (PSF) models. The Monte Carlo-based method under consideration involves an extensive model of the system response matrix based on Monte Carlo simulations and is computed off-line and stored on disk. Methods: Comparisons were performed using simulated and experimental data of the commercial small animal PET scanner rPET. Results: The results demonstrate that the orthogonal distance-based ray-tracer and Siddon ray-tracer using PSF image-space convolutions yield better images in terms of contrast and spatial resolution than those obtained after using the conventional method and the multiray-based S-RT. Furthermore, the Monte Carlo-based method yields slight improvements in terms of contrast and spatial resolution with respect to these geometrical projectors. Conclusions: The orthogonal distance-based ray-tracer and Siddon ray-tracer using PSF image-space convolutions represent satisfactory alternatives to factorizing the system matrix or to the conventional on-the-fly ray-tracing methods for list-mode reconstruction, where an extensive modeling based on Monte Carlo simulations is unfeasible. |
| Address |
[Aguiar, Pablo] Univ Santiago de Compostela, Dept Fis Particulas, Complexo Hosp Univ Santiago de Compostela, Fdn IDICHUS IDIS, Santiago De Compostela, Spain, Email: pablo.aguiar.fernandez@sergas.es |
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Thesis |
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| Publisher |
Amer Assoc Physicists Medicine Amer Inst Physics |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0094-2405 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
ISI:000283747600015 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ elepoucu @ |
Serial |
338 |
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| Author |
Wagner, C.; Verde, L.; Boubekeur, L. |
| Title |
N-body simulations with generic non-Gaussian initial conditions I: power spectrum and halo mass function |
Type |
Journal Article |
| Year |
2010 |
Publication |
Journal of Cosmology and Astroparticle Physics |
Abbreviated Journal |
J. Cosmol. Astropart. Phys. |
| Volume |
10 |
Issue |
10 |
Pages |
022 - 24pp |
| Keywords |
power spectrum; cosmological simulations; initial conditions and eternal universe; galaxy clusters |
| Abstract |
We address the issue of setting up generic non-Gaussian initial conditions for N-body simulations. We consider inflationary-motivated primordial non-Gaussianity where the perturbations in the Bardeen potential are given by a dominant Gaussian part plus a non-Gaussian part specified by its bispectrum. The approach we explore here is suitable for any bispectrum, i.e. it does not have to be of the so-called separable or factorizable form. The procedure of generating a non-Gaussian field with a given bispectrum (and a given power spectrum for the Gaussian component) is not univocal, and care must be taken so that higher-order corrections do not leave a too large signature on the power spectrum. This is so far a limiting factor of our approach. We then run N-body simulations for the most popular inflationary-motivated non-Gaussian shapes. The halo mass function and the non-linear power spectrum agree with theoretical analytical approximations proposed in the literature, even if they were so far developed and tested only for a particular shape (the local one). We plan to make the simulations outputs available to the community via the non-Gaussian simulations comparison project web site http://icc.ub.edu/similar to liciaverde/NGSCP.html. |
| Address |
[Wagner, Christian; Verde, Licia] Univ Barcelona, ICCUB IEEC, E-08028 Barcelona, Spain, Email: cwagner@icc.ub.edu |
| Corporate Author |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1475-7516 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
ISI:000283577600013 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ elepoucu @ |
Serial |
339 |
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| Author |
Olleros, P.; Caballero, L.; Domingo-Pardo, C.; Babiano, V.; Ladarescu, I.; Calvo, D.; Gramage, P.; Nacher, E.; Tain, J.L.; Tolosa, A. |
| Title |
On the performance of large monolithic LaCl3(Ce) crystals coupled to pixelated silicon photosensors |
Type |
Journal Article |
| Year |
2018 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
| Volume |
13 |
Issue |
|
Pages |
P03014 - 17pp |
| Keywords |
Compton imaging; Detector modelling and simulations I (interaction of radiation with matter interaction of photons with matter interaction of hadrons with matter etc); Gamma detectors (scintillators CZT HPG HgI etc); Instrumentation and methods for time-of-flight (TOF); spectroscopy |
| Abstract |
We investigate the performance of large area radiation detectors, with high energy-and spatial-resolution, intended for the development of a Total Energy Detector with gamma-ray imaging capability, so-called i-TED. This new development aims for an enhancement in detection sensitivity in time-of-flight neutron capture measurements, versus the commonly used C6D6 liquid scintillation total-energy detectors. In this work, we study in detail the impact of the readout photosensor on the energy response of large area (50 x 50 mm(2)) monolithic LaCl3(Ce) crystals, in particular when replacing a conventional mono-cathode photomultiplier tube by an 8 x 8 pixelated silicon photomultiplier. Using the largest commercially available monolithic SiPM array (25 cm(2)), with a pixel size of 6 x 6 mm(2), we have measured an average energy resolution of 3.92% FWHM at 662 keV for crystal thick-nesses of 10, 20 and 30 mm. The results are confronted with detailed Monte Carlo (MC) calculations, where optical processes and properties have been included for the reliable tracking of the scintillation photons. After the experimental validation of the MC model, we use our MC code to explore the impact of a smaller photosensor segmentation on the energy resolution. Our optical MC simulations predict only a marginal deterioration of the spectroscopic performance for pixels of 3 x 3 mm(2). |
| Address |
[Olleros, P.; Caballero, L.; Domingo-Pardo, C.; Babiano, V.; Ladarescu, I.; Calvo, D.; Gramage, P.; Tain, J. L.; Tolosa, A.] Univ Valencia, CSIC, Inst Fis Corpuscular, C Catedrat Jose Beltran 2, Paterna 46980, Spain, Email: Luis.Caballero@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1748-0221 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000428146300004 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
3542 |
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| Author |
Muñoz, E.; Barrio, J.; Bernabeu, J.; Etxebeste, A.; Lacasta, C.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F. |
| Title |
Study and comparison of different sensitivity models for a two-plane Compton camera |
Type |
Journal Article |
| Year |
2018 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
63 |
Issue |
13 |
Pages |
135004 - 19pp |
| Keywords |
Compton camera imaging; MLEM; Monte Carlo simulations; image quality |
| Abstract |
Given the strong variations in the sensitivity of Compton cameras for the detection of events originating from different points in the field of view (FoV), sensitivity correction is often necessary in Compton image reconstruction. Several approaches for the calculation of the sensitivity matrix have been proposed in the literature. While most of these models are easily implemented and can be useful in many cases, they usually assume high angular coverage over the scattered photon, which is not the case for our prototype. In this work, we have derived an analytical model that allows us to calculate a detailed sensitivity matrix, which has been compared to other sensitivity models in the literature. Specifically, the proposed model describes the probability of measuring a useful event in a two-plane Compton camera, including the most relevant physical processes involved. The model has been used to obtain an expression for the system and sensitivity matrices for iterative image reconstruction. These matrices have been validated taking Monte Carlo simulations as a reference. In order to study the impact of the sensitivity, images reconstructed with our sensitivity model and with other models have been compared. Images have been reconstructed from several simulated sources, including point-like sources and extended distributions of activity, and also from experimental data measured with Na-22 sources. Results show that our sensitivity model is the best suited for our prototype. Although other models in the literature perform successfully in many scenarios, they are not applicable in all the geometrical configurations of interest for our system. In general, our model allows to effectively recover the intensity of point-like sources at different positions in the FoV and to reconstruct regions of homogeneous activity with minimal variance. Moreover, it can be employed for all Compton camera configurations, including those with low angular coverage over the scatterer. |
| Address |
[Munoz, Enrique; Barrio, John; Bernabeu, Jose; Etxebeste, Ane; Lacasta, Carlos; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, IFIC, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es |
| Corporate Author |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0031-9155 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000436390800004 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
3639 |
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| Author |
Ortiz Arciniega, J.L.; Carrio, F.; Valero, A. |
| Title |
FPGA implementation of a deep learning algorithm for real-time signal reconstruction in particle detectors under high pile-up conditions |
Type |
Journal Article |
| Year |
2019 |
Publication |
Journal of Instrumentation |
Abbreviated Journal |
J. Instrum. |
| Volume |
14 |
Issue |
|
Pages |
P09002 - 13pp |
| Keywords |
Data processing methods; Pattern recognition; cluster finding; calibration and fitting methods; Simulation methods and programs |
| Abstract |
The analog signals generated in the read-out electronics of particle detectors are shaped prior to the digitization in order to improve the signal to noise ratio (SNR). The real amplitude of the analog signal is then obtained using digital filters, which provides information about the energy deposited in the detector. The classical digital filters have a good performance in ideal situations with Gaussian electronic noise and no pulse shape distortion. However, high-energy particle colliders, such as the Large Hadron Collider (LHC) at CERN, can produce multiple simultaneous events, which produce signal pileup. The performance of classical digital filters deteriorates in these conditions since the signal pulse shape gets distorted. In addition, this type of experiments produces a high rate of collisions, which requires high throughput data acquisitions systems. In order to cope with these harsh requirements, new read-out electronics systems are based on high-performance FPGAs, which permit the utilization of more advanced real-time signal reconstruction algorithms. In this paper, a deep learning method is proposed for real-time signal reconstruction in high pileup particle detectors. The performance of the new method has been studied using simulated data and the results are compared with a classical FIR filter method. In particular, the signals and FIR filter used in the ATLAS Tile Calorimeter are used as benchmark. The implementation, resources usage and performance of the proposed Neural Network algorithm in FPGA are also presented. |
| Address |
[Ortiz Arciniega, J. L.] Univ Valencia, Avinguda Univ S-N, Burjassot, Spain, Email: orarjo@alumni.uv.es |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1748-0221 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
WOS:000486990000002 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
4150 |
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| Author |
Roser, J.; Muñoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J.F. |
| Title |
Image reconstruction for a multi-layer Compton telescope: an analytical model for three interaction events |
Type |
Journal Article |
| Year |
2020 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
65 |
Issue |
14 |
Pages |
145005 - 17pp |
| Keywords |
Compton camera; Compton imaging; hadron therapy; image reconstruction; lm-mlem; monte carlo simulations; multi-layer Compton telescope |
| Abstract |
Compton Cameras are electronically collimated photon imagers suitable for sub-MeV to few MeV gamma-ray detection. Such features are desirable to enablein vivorange verification in hadron therapy, through the detection of secondary Prompt Gammas. A major concern with this technique is the poor image quality obtained when the incoming gamma-ray energy is unknown. Compton Cameras with more than two detector planes (multi-layer Compton Cameras) have been proposed as a solution, given that these devices incorporate more signal sequences of interactions to the conventional two interaction events. In particular, three interaction events convey more spectral information as they allow inferring directly the incident gamma-ray energy. A three-layer Compton Telescope based on continuous Lanthanum (III) Bromide crystals coupled to Silicon Photomultipliers is being developed at the IRIS group of IFIC-Valencia. In a previous work we proposed a spectral reconstruction algorithm for two interaction events based on an analytical model for the formation of the signal. To fully exploit the capabilities of our prototype, we present here an extension of the model for three interaction events. Analytical expressions of the sensitivity and the System Matrix are derived and validated against Monte Carlo simulations. Implemented in a List Mode Maximum Likelihood Expectation Maximization algorithm, the proposed model allows us to obtain four-dimensional (energy and position) images by using exclusively three interaction events. We are able to recover the correct spectrum and spatial distribution of gamma-ray sources when ideal data are employed. However, the uncertainties associated to experimental measurements result in a degradation when real data from complex structures are employed. Incorrect estimation of the incident gamma-ray interaction positions, and missing deposited energy associated with escaping secondaries, have been identified as the causes of such degradation by means of a detailed Monte Carlo study. As expected, our current experimental resolution and efficiency to three interaction events prevents us from correctly recovering complex structures of radioactive sources. However, given the better spectral information conveyed by three interaction events, we expect an improvement of the image quality of conventional Compton imaging when including such events. In this regard, future development includes the incorporation of the model assessed in this work to the two interaction events model in order to allow using simultaneously two and three interaction events in the image reconstruction. |
| Address |
[Roser, J.; Munoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J. F.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: Jorge.Roser@ific.uv.es |
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Thesis |
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| Publisher |
Iop Publishing Ltd |
Place of Publication |
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| Language |
English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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0031-9155 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
WOS:000552701600001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
4481 |
| Permanent link to this record |
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| Author |
Gimenez-Alventosa, V.; Gimenez, V.; Oliver, S. |
| Title |
PenRed: An extensible and parallel Monte-Carlo framework for radiation transport based on PENELOPE |
Type |
Journal Article |
| Year |
2021 |
Publication |
Computer Physics Communications |
Abbreviated Journal |
Comput. Phys. Commun. |
| Volume |
267 |
Issue |
|
Pages |
108065 - 12pp |
| Keywords |
Radiation transport; Monte Carlo simulation; Electron-photon showers; Parallel computing; MPI; Medical physics |
| Abstract |
Monte Carlo methods provide detailed and accurate results for radiation transport simulations. Unfortunately, the high computational cost of these methods limits its usage in real-time applications. Moreover, existing computer codes do not provide a methodology for adapting these kinds of simulations to specific problems without advanced knowledge of the corresponding code system, and this restricts their applicability. To help solve these current limitations, we present PenRed, a general-purpose, standalone, extensible and modular framework code based on PENELOPE for parallel Monte Carlo simulations of electron-photon transport through matter. It has been implemented in C++ programming language and takes advantage of modern object-oriented technologies. In addition, PenRed offers the capability to read and process DICOM images as well as to construct and simulate image-based voxelized geometries, so as to facilitate its usage in medical applications. Our framework has been successfully verified against the original PENELOPE Fortran code. Furthermore, the implemented parallelism has been tested showing a significant improvement in the simulation time without any loss in precision of results. Program summary Program title: PenRed: Parallel Engine for Radiation Energy Deposition. CPC Library link to program files: https://doi .org /10 .17632/rkw6tvtngy.1 Licensing provision: GNU Affero General Public License (AGPL). Programming language: C++ standard 2011. Nature of problem: Monte Carlo simulations usually require a huge amount of computation time to achieve low statistical uncertainties. In addition, many applications necessitate particular characteristics or the extraction of specific quantities from the simulation. However, most available Monte Carlo codes do not provide an efficient parallel and truly modular structure which allows users to easily customise their code to suit their needs without an in-depth knowledge of the code system. Solution method: PenRed is a fully parallel, modular and customizable framework for Monte Carlo simulations of the passage of radiation through matter. It is based on the PENELOPE [1] code system, from which inherits its unique physics models and tracking algorithms for charged particles. PenRed has been coded in C++ following an object-oriented programming paradigm restricted to the C++11 standard. Our engine implements parallelism via a double approach: on the one hand, by using standard C++ threads for shared memory, improving the access and usage of the memory, and, on the other hand, via the MPI standard for distributed memory infrastructures. Notice that both kinds of parallelism can be combined together in the same simulation. Moreover, both threads and MPI processes, can be balanced using the builtin load balance system (RUPER-LB [30]) to maximise the performance on heterogeneous infrastructures. In addition, PenRed provides a modular structure with methods designed to easily extend its functionality. Thus, users can create their own independent modules to adapt our engine to their needs without changing the original modules. Furthermore, user extensions will take advantage of the builtin parallelism without any extra effort or knowledge of parallel programming. Additional comments including restrictions and unusual features: PenRed has been compiled in linux systems withg++ of GCC versions 4.8.5, 7.3.1, 8.3.1 and 9; clang version 3.4.2 and intel C++ compiler (icc) version 19.0.5.281. Since it is a C++11-standard compliant code, PenRed should be able to compile with any compiler with C++11 support. In addition, if the code is compiled without MPI support, it does not require any non standard library. To enable MPI capabilities, the user needs to install whatever available MPI implementation, such as openMPI [24] or mpich [25], which can be found in the repositories of any linux distribution. Finally, to provide DICOM processing support, PenRed can be optionally compiled using the dicom toolkit (dcmtk) [32] library. Thus, PenRed has only two optional dependencies, an MPI implementation and the dcmtk library. |
| Address |
[Gimenez-Alventosa, V] Univ Politecn Valencia, Inst Instrumentac Imagen Mol I3M, Ctr Mixto CSIC, Cami Vera S-N, Valencia 46022, Spain, Email: vicent.gimenez@i3m.upv.es; |
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| Publisher |
Elsevier |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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0010-4655 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
WOS:000678508900001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
4907 |
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| Author |
Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Muñoz, E.; Ros, A.; Viegas, R.; Llosa, G. |
| Title |
Joint image reconstruction algorithm in Compton cameras |
Type |
Journal Article |
| Year |
2022 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
67 |
Issue |
15 |
Pages |
155009 - 15pp |
| Keywords |
Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope |
| Abstract |
Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging. |
| Address |
[Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Munoz, E.; Ros, A.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Jorge.Roser@ific.uv.es |
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| Publisher |
IOP Publishing Ltd |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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0031-9155 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
WOS:000827830200001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
5298 |
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| Author |
Borys, D. et al; Brzezinski, K. |
| Title |
ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging |
Type |
Journal Article |
| Year |
2022 |
Publication |
Physics in Medicine and Biology |
Abbreviated Journal |
Phys. Med. Biol. |
| Volume |
67 |
Issue |
22 |
Pages |
224002 - 15pp |
| Keywords |
proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging |
| Abstract |
Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022). |
| Address |
[Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl |
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| Publisher |
IOP Publishing Ltd |
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| Language |
English |
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| ISSN |
0031-9155 |
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| Notes |
WOS:000885248200001 |
Approved |
no |
| Is ISI |
yes |
International Collaboration |
no |
| Call Number |
IFIC @ pastor @ |
Serial |
5416 |
| Permanent link to this record |
