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Author Muñoz, E.; Barrio, J.; Bernabeu, J.; Etxebeste, A.; Lacasta, C.; Llosa, G.; Ros, A.; Roser, J.; Oliver, J.F.
Title Study and comparison of different sensitivity models for a two-plane Compton camera Type Journal Article
Year 2018 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 63 Issue 13 Pages 135004 - 19pp
Keywords Compton camera imaging; MLEM; Monte Carlo simulations; image quality
Abstract Given the strong variations in the sensitivity of Compton cameras for the detection of events originating from different points in the field of view (FoV), sensitivity correction is often necessary in Compton image reconstruction. Several approaches for the calculation of the sensitivity matrix have been proposed in the literature. While most of these models are easily implemented and can be useful in many cases, they usually assume high angular coverage over the scattered photon, which is not the case for our prototype. In this work, we have derived an analytical model that allows us to calculate a detailed sensitivity matrix, which has been compared to other sensitivity models in the literature. Specifically, the proposed model describes the probability of measuring a useful event in a two-plane Compton camera, including the most relevant physical processes involved. The model has been used to obtain an expression for the system and sensitivity matrices for iterative image reconstruction. These matrices have been validated taking Monte Carlo simulations as a reference. In order to study the impact of the sensitivity, images reconstructed with our sensitivity model and with other models have been compared. Images have been reconstructed from several simulated sources, including point-like sources and extended distributions of activity, and also from experimental data measured with Na-22 sources. Results show that our sensitivity model is the best suited for our prototype. Although other models in the literature perform successfully in many scenarios, they are not applicable in all the geometrical configurations of interest for our system. In general, our model allows to effectively recover the intensity of point-like sources at different positions in the FoV and to reconstruct regions of homogeneous activity with minimal variance. Moreover, it can be employed for all Compton camera configurations, including those with low angular coverage over the scatterer.
Address [Munoz, Enrique; Barrio, John; Bernabeu, Jose; Etxebeste, Ane; Lacasta, Carlos; Llosa, Gabriela; Ros, Ana; Roser, Jorge; Oliver, Josep F.] Univ Valencia, CSIC, Inst Fis Corpuscular, IFIC, Valencia, Spain, Email: Enrique.Munoz@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000436390800004 Approved no
Is ISI yes International Collaboration (up) no
Call Number IFIC @ pastor @ Serial 3639
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Author Roser, J.; Muñoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J.F.
Title Image reconstruction for a multi-layer Compton telescope: an analytical model for three interaction events Type Journal Article
Year 2020 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 65 Issue 14 Pages 145005 - 17pp
Keywords Compton camera; Compton imaging; hadron therapy; image reconstruction; lm-mlem; monte carlo simulations; multi-layer Compton telescope
Abstract Compton Cameras are electronically collimated photon imagers suitable for sub-MeV to few MeV gamma-ray detection. Such features are desirable to enablein vivorange verification in hadron therapy, through the detection of secondary Prompt Gammas. A major concern with this technique is the poor image quality obtained when the incoming gamma-ray energy is unknown. Compton Cameras with more than two detector planes (multi-layer Compton Cameras) have been proposed as a solution, given that these devices incorporate more signal sequences of interactions to the conventional two interaction events. In particular, three interaction events convey more spectral information as they allow inferring directly the incident gamma-ray energy. A three-layer Compton Telescope based on continuous Lanthanum (III) Bromide crystals coupled to Silicon Photomultipliers is being developed at the IRIS group of IFIC-Valencia. In a previous work we proposed a spectral reconstruction algorithm for two interaction events based on an analytical model for the formation of the signal. To fully exploit the capabilities of our prototype, we present here an extension of the model for three interaction events. Analytical expressions of the sensitivity and the System Matrix are derived and validated against Monte Carlo simulations. Implemented in a List Mode Maximum Likelihood Expectation Maximization algorithm, the proposed model allows us to obtain four-dimensional (energy and position) images by using exclusively three interaction events. We are able to recover the correct spectrum and spatial distribution of gamma-ray sources when ideal data are employed. However, the uncertainties associated to experimental measurements result in a degradation when real data from complex structures are employed. Incorrect estimation of the incident gamma-ray interaction positions, and missing deposited energy associated with escaping secondaries, have been identified as the causes of such degradation by means of a detailed Monte Carlo study. As expected, our current experimental resolution and efficiency to three interaction events prevents us from correctly recovering complex structures of radioactive sources. However, given the better spectral information conveyed by three interaction events, we expect an improvement of the image quality of conventional Compton imaging when including such events. In this regard, future development includes the incorporation of the model assessed in this work to the two interaction events model in order to allow using simultaneously two and three interaction events in the image reconstruction.
Address [Roser, J.; Munoz, E.; Barrientos, L.; Barrio, J.; Bernabeu, J.; Borja-Lloret, M.; Etxebeste, A.; Llosa, G.; Ros, A.; Viegas, R.; Oliver, J. F.] Inst Fis Corpuscular IFIC CSIC UVEG, Valencia, Spain, Email: Jorge.Roser@ific.uv.es
Corporate Author Thesis
Publisher Iop Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000552701600001 Approved no
Is ISI yes International Collaboration (up) no
Call Number IFIC @ pastor @ Serial 4481
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Author Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Muñoz, E.; Ros, A.; Viegas, R.; Llosa, G.
Title Joint image reconstruction algorithm in Compton cameras Type Journal Article
Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 67 Issue 15 Pages 155009 - 15pp
Keywords Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope
Abstract Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging.
Address [Roser, J.; Barrientos, L.; Bernabeu, J.; Borja-Lloret, M.; Munoz, E.; Ros, A.; Viegas, R.; Llosa, G.] CSIC UV, Inst Fis Corpuscular IFIC, Valencia, Spain, Email: Jorge.Roser@ific.uv.es
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000827830200001 Approved no
Is ISI yes International Collaboration (up) no
Call Number IFIC @ pastor @ Serial 5298
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Author Borys, D. et al; Brzezinski, K.
Title ProTheRaMon-a GATE simulation framework for proton therapy range monitoring using PET imaging Type Journal Article
Year 2022 Publication Physics in Medicine and Biology Abbreviated Journal Phys. Med. Biol.
Volume 67 Issue 22 Pages 224002 - 15pp
Keywords proton therapy; GATE; Monte Carlo simulations; J-PET; medical imaging
Abstract Objective. This paper reports on the implementation and shows examples of the use of the ProTheRaMon framework for simulating the delivery of proton therapy treatment plans and range monitoring using positron emission tomography (PET). ProTheRaMon offers complete processing of proton therapy treatment plans, patient CT geometries, and intra-treatment PET imaging, taking into account therapy and imaging coordinate systems and activity decay during the PET imaging protocol specific to a given proton therapy facility. We present the ProTheRaMon framework and illustrate its potential use case and data processing steps for a patient treated at the Cyclotron Centre Bronowice (CCB) proton therapy center in Krakow, Poland. Approach. The ProTheRaMon framework is based on GATE Monte Carlo software, the CASToR reconstruction package and in-house developed Python and bash scripts. The framework consists of five separated simulation and data processing steps, that can be further optimized according to the user's needs and specific settings of a given proton therapy facility and PET scanner design. Main results. ProTheRaMon is presented using example data from a patient treated at CCB and the J-PET scanner to demonstrate the application of the framework for proton therapy range monitoring. The output of each simulation and data processing stage is described and visualized. Significance. We demonstrate that the ProTheRaMon simulation platform is a high-performance tool, capable of running on a computational cluster and suitable for multi-parameter studies, with databases consisting of large number of patients, as well as different PET scanner geometries and settings for range monitoring in a clinical environment. Due to its modular structure, the ProTheRaMon framework can be adjusted for different proton therapy centers and/or different PET detector geometries. It is available to the community via github (Borys et al 2022).
Address [Borys, Damian] Silesian Tech Univ, Dept Syst Biol & Engn, Gliwice, Poland, Email: damin.borys@polsl.pl
Corporate Author Thesis
Publisher IOP Publishing Ltd Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9155 ISBN Medium
Area Expedition Conference
Notes WOS:000885248200001 Approved no
Is ISI yes International Collaboration (up) no
Call Number IFIC @ pastor @ Serial 5416
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Author AGATA Collaboration (Soderstrom, P.A. et al); Gadea, A.
Title Interaction position resolution simulations and in-beam measurements of the AGATA HPGe detectors Type Journal Article
Year 2011 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 638 Issue 1 Pages 96-109
Keywords gamma-ray tracking; AGATA; Monte Carlo simulations; HPGe detectors; Fusion-evaporation reactions
Abstract The interaction position resolution of the segmented HPGe detectors of an AGATA triple cluster detector has been studied through Monte Carlo simulations and in an in-beam experiment. A new method based on measuring the energy resolution of Doppler-corrected gamma-ray spectra at two different target to detector distances is described. This gives the two-dimensional position resolution in the plane perpendicular to the direction of the emitted gamma-ray. The gamma-ray tracking was used to determine the full energy of the gamma-rays and the first interaction point, which is needed for the Doppler correction. Five different heavy-ion induced fusion-evaporation reactions and a reference reaction were selected for the simulations. The results of the simulations show that the method works very well and gives a systematic deviation of <1 mm in the FVVHM of the interaction position resolution for the gamma-ray energy range from 60 keV to 5 MeV. The method was tested with real data from an in-beam measurement using a (30)5i beam at 64 MeV on a thin C-12 target. Pulse-shape analysis of the digitized detector waveforms and gamma-ray tracking was performed to determine the position of the first interaction point, which was used for the Doppler corrections. Results of the dependency of the interaction position resolution on the gamma-ray energy and on the energy, axial location and type of the first interaction point, are presented. The FVVHM of the interaction position resolution varies roughly linearly as a function of gamma-ray energy from 8.5 mm at 250 key to 4 mm at 1.5 MeV, and has an approximately constant value of about 4 mm in the gamma-ray energy range from 1.5 to 4 MeV.
Address [Soderstrom, P. -A.; Nyberg, J.; Al-Adili, A.; Atac, A.; Veyssiere, C.] Uppsala Univ, Dept Phys & Astron, SE-75121 Uppsala, Sweden, Email: P-A.Soderstrom@physics.uu.se
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes ISI:000290082600015 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 619
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Author Hornillos, M.B.G.; Gorlychev, V.; Caballero, R.; Cortes, G.; Poch, A.; Pretel, C.; Calvino, F.; Tain, J.L.; Algora, A.; Agramunt, J.; Cano-Ott, D.; Martinez, T.; Mendoza, E.; Rissanen, J.; Aysto, J.; Jokinen, A.; Eronen, T.; Moore, I.; Penttila, H.
Title Monte Carlo Simulations for the Study of a Moderated Neutron Detector Type Journal Article
Year 2011 Publication Journal of the Korean Physical Society Abbreviated Journal J. Korean Phys. Soc.
Volume 59 Issue 2 Pages 1573-1576
Keywords Monte Carlo simulations; GEANT4; MCNPX; Beta delayed neutron emission; Neutron detector
Abstract This work presents the Monte Carlo simulations performed with the MCNPX and GEANT4 codes for the design of a BEta deLayEd Neutron detector, BELEN-20. This detector will be used for the study of beta delayed neutron emission and consists of a block of polyethylene with dimensions 90 x 90 x 80 cm(3) and 20 cylindrical (3)He gas counters. The results of these simulations have been validated experimentally with a (252)Cf source in the laboratory at UPC, Barcelona. Also the first experiment with this detector has been carried out in November 2009 in JYFL, Finland. In this experiment the neutron emission probability after beta decay of the fission products (88)Br, (94,95)Rb, and (138)I has been measured; this data is still under analysis. Simulations with MCNPX and GEANT4 have been performed in order to obtain the efficiency of the BELEN-20 detector for each of the above nuclei using the neutron energy distribution corresponding to each nucleus.
Address [Hornillos, MBG; Gorlychev, V; Caballero, R; Cortes, G; Poch, A; Pretel, C; Calvino, F] Univ Politecn Cataluna, Seccio Engn Nucl, E-08028 Barcelona, Spain, Email: belen.gomez@upc.edu
Corporate Author Thesis
Publisher Korean Physical Soc Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0374-4884 ISBN Medium
Area Expedition Conference
Notes WOS:000294080700028 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ elepoucu @ Serial 733
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Author Langer, C.; Algora, A.; Couture, A.; Csatlos, M.; Gulyas, J.; Heil, M.; Krasznahorkay, A.; O'Donnell, J.M.; Plag, R.; Reifarth, R.; Stuhl, L.; Sonnabend, K.; Tornyi, T.; Tovesson, F.
Title Simulations and developments of the Low Energy Neutron detector Array LENA Type Journal Article
Year 2011 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 659 Issue 1 Pages 411-418
Keywords Monte Carlo simulations; Charge-exchange reactions; Scintillation detectors; Neutron detector
Abstract Prototypes of the Low Energy Neutron detector Array (LENA) have been tested and compared with detailed GEANT simulations. LENA will consist of plastic scintillation bars with the dimensions 1000 x 45 x 10 mm(3). The tests have been performed with gamma-ray sources and neutrons originating from the neutron-induced fission of (235)U. The simulations agreed very well with the measured response and were therefore used to simulate the response to mono-energetic neutrons with different detection thresholds. LENA will be used to detect low-energy neutrons from (p,n)-type reactions with low momentum transfer foreseen at the R(3)B and EXL setups at FAIR, Darmstadt.
Address [Langer, C.; Heil, M.; Plag, R.; Reifarth, R.] GSI Helmholtzzentrum Schwerionenforsch GmbH, D-64291 Darmstadt, Germany, Email: c.langer@gsi.de
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000297826100057 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 833
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Author Campanario, F.; Kubocz, M.
Title Higgs boson CP-properties of the gluonic contributions in Higgs plus three jet production via gluon fusion at the LHC Type Journal Article
Year 2014 Publication Journal of High Energy Physics Abbreviated Journal J. High Energy Phys.
Volume 10 Issue 10 Pages 173 - 16pp
Keywords QCD Phenomenology; Monte Carlo Simulations
Abstract in high energy hadronic collisions, a general CP-violating Higgs boson Phi with accompanying jets can be efficiently produced via gluon fusion, which is mediated by heavy quark loops. In this article, we study the dominant sub-channel gg -> ggg Phi of the gluon fusion production process with triple real emission corrections at order alpha(5)(s). We go beyond the heavy top-quark approximation and include the full mass dependence of the top- and bottom-quark contributions. Furthermore, in a specific model we demonstrate the features of our program and show the impact of bottom-quark loop contributions in combination with large values of tan beta on differential distributions sensitive to CP-rneasurements of the Higgs boson.
Address [Campanario, Francisco] Univ Valencia CSIC, IFIC, Div Theory, E-46100 Valencia, Spain, Email: francisco.campanario@ific.uv.es;
Corporate Author Thesis
Publisher Springer Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1029-8479 ISBN Medium
Area Expedition Conference
Notes WOS:000344652800003 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 2007
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Author Guadilla, V. et al; Algora, A.; Tain, J.L.; Agramunt, J.; Jordan, D.; Monserrate, M.; Montaner-Piza, A.; Orrigo, S.E.A.; Rubio, B.; Valencia, E.
Title Characterization of a cylindrical plastic beta-detector with Monte Carlo simulations of optical photons Type Journal Article
Year 2017 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 854 Issue Pages 134-138
Keywords Plastic scintillators; Monte Carlo simulations; Total absorption spectroscopy; Optical photons
Abstract In this work we report on the Monte Carlo study performed to understand and reproduce experimental measurements of a new plastic beta-detector with cylindrical geometry. Since energy deposition simulations differ from the experimental measurements for such a geometry, we show how the simulation of production and transport of optical photons does allow one to obtain the shapes of the experimental spectra. Moreover, taking into account the computational effort associated with this kind of simulation, we develop a method to convert the simulations of energy deposited into light collected, depending only on the interaction point in the detector. This method represents a useful solution when extensive simulations have to be done, as in the case of the calculation of the response function of the spectrometer in a total absorption gamma-ray spectroscopy analysis.
Address [Guadilla, V.; Algora, A.; Tain, J. L.; Agramunt, J.; Gelletly, W.; Jordan, D.; Monserrate, M.; Montaner-Piza, A.; Orrigo, S. E. A.; Rubio, B.; Valencia, E.] Univ Valencia, CSIC, Inst Fis Corpuscular, E-46071 Valencia, Spain, Email: victor.guadilla@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000398869100018 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 3052
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Author Guadilla, V. et al; Tain, J.L.; Algora, A.; Agramunt, J.; Gelletly, W.; Jordan, D.; Monserrate, M.; Montaner-Piza, A.; Orrigo, S.E.A.; Rubio, B.; Valencia, E.
Title Characterization and performance of the DTAS detector Type Journal Article
Year 2018 Publication Nuclear Instruments & Methods in Physics Research A Abbreviated Journal Nucl. Instrum. Methods Phys. Res. A
Volume 910 Issue Pages 79-89
Keywords beta decay; Total absorption gamma-ray spectrometer; Exotic nuclei; NaI(Tl) detector; Non-proportional scintillation light yield; Monte Carlo simulations
Abstract DTAS is a segmented total absorption y-ray spectrometer developed for the DESPEC experiment at FAIR. It is composed of up to eighteen NaI(Tl) crystals. In this work we study the performance of this detector with laboratory sources and also under real experimental conditions. We present a procedure to reconstruct offline the sum of the energy deposited in all the crystals of the spectrometer, which is complicated by the effect of NaI(Tl) light-yield non-proportionality. The use of a system to correct for time variations of the gain in individual detector modules, based on a light pulse generator, is demonstrated. We describe also an event-based method to evaluate the summing-pileup electronic distortion in segmented spectrometers. All of this allows a careful characterization of the detector with Monte Carlo simulations that is needed to calculate the response function for the analysis of total absorption gamma-ray spectroscopy data. Special attention was paid to the interaction of neutrons with the spectrometer, since they are a source of contamination in studies of beta-delayed neutron emitting nuclei.
Address [Guadilla, V; Tain, J. L.; Algora, A.; Agramunt, J.; Gelletly, W.; Jordan, D.; Monserrate, M.; Montaner-Piza, A.; Orrigo, S. E. A.; Rubio, B.; Valencia, E.] CSIC Univ Valencia, Inst Fis Corpuscular, E-46071 Valencia, Spain, Email: guadilla@ific.uv.es
Corporate Author Thesis
Publisher Elsevier Science Bv Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-9002 ISBN Medium
Area Expedition Conference
Notes WOS:000453652500010 Approved no
Is ISI yes International Collaboration (up) yes
Call Number IFIC @ pastor @ Serial 3847
Permanent link to this record