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Blanes-Selva, V., Ruiz-Garcia, V., Tortajada, S., Benedi, J. M., Valdivieso, B., & Garcia-Gomez, J. M. (2021). Design of 1-year mortality forecast at hospital admission: A machine learning approach. Health Inform. J., 27(1), 13pp.
Abstract: Palliative care is referred to a set of programs for patients that suffer life-limiting illnesses. These programs aim to maximize the quality of life (QoL) for the last stage of life. They are currently based on clinical evaluation of the risk of 1-year mortality. The main aim of this work is to develop and validate machine-learning-based models to predict the exitus of a patient within the next year using data gathered at hospital admission. Five machine-learning techniques were applied using a retrospective dataset. The evaluation was performed with five metrics computed by a resampling strategy: Accuracy, the area under the ROC curve, Specificity, Sensitivity, and the Balanced Error Rate. All models reported an AUC ROC from 0.857 to 0.91. Specifically, Gradient Boosting Classifier was the best model, producing an AUC ROC of 0.91, a sensitivity of 0.858, a specificity of 0.808, and a BER of 0.1687. Information from standard procedures at hospital admission combined with machine learning techniques produced models with competitive discriminative power. Our models reach the best results reported in the state of the art. These results demonstrate that they can be used as an accurate data-driven palliative care criteria inclusion.
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Caron, S., Eckner, C., Hendriks, L., Johannesson, G., Ruiz de Austri, R., & Zaharijas, G. (2023). Mind the gap: the discrepancy between simulation and reality drives interpretations of the Galactic Center Excess. J. Cosmol. Astropart. Phys., 06(6), 013–56pp.
Abstract: The Galactic Center Excess (GCE) in GeV gamma rays has been debated for over a decade, with the possibility that it might be due to dark matter annihilation or undetected point sources such as millisecond pulsars (MSPs). This study investigates how the gamma-ray emission model (-yEM) used in Galactic center analyses affects the interpretation of the GCE's nature. To address this issue, we construct an ultra-fast and powerful inference pipeline based on convolutional Deep Ensemble Networks. We explore the two main competing hypotheses for the GCE using a set of-yEMs with increasing parametric freedom. We calculate the fractional contribution (fsrc) of a dim population of MSPs to the total luminosity of the GCE and analyze its dependence on the complexity of the ryEM. For the simplest ryEM, we obtain fsrc = 0.10 f 0.07, while the most complex model yields fsrc = 0.79 f 0.24. In conclusion, we find that the statement about the nature of the GCE (dark matter or not) strongly depends on the assumed ryEM. The quoted results for fsrc do not account for the additional uncertainty arising from the fact that the observed gamma-ray sky is out-of-distribution concerning the investigated ryEM iterations. We quantify the reality gap between our ryEMs using deep-learning-based One-Class Deep Support Vector Data Description networks, revealing that all employed ryEMs have gaps to reality. Our study casts doubt on the validity of previous conclusions regarding the GCE and dark matter, and underscores the urgent need to account for the reality gap and consider previously overlooked “out of domain” uncertainties in future interpretations.
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n_TOF Collaboration(Patronis, N. et al), Babiano-Suarez, V., Balibrea Correa, J., Domingo-Pardo, C., Ladarescu, I., & Lerendegui-Marco, J. (2023). Status report of the n_TOF facility after the 2nd CERN long shutdown period. EPJ Tech. Instrum., 10(1), 13–10pp.
Abstract: During the second long shutdown period of the CERN accelerator complex (LS2, 2019-2021), several upgrade activities took place at the nTOF facility. The most important have been the replacement of the spallation target with a next generation nitrogen-cooled lead target. Additionally, a new experimental area, at a very short distance from the target assembly (the NEAR Station) was established. In this paper, the core commissioning actions of the new installations are described. The improvement in the nTOF infrastructure was accompanied by several detector development projects. All these upgrade actions are discussed, focusing mostly on the future perspectives of the n_TOF facility. Furthermore, some indicative current and future measurements are briefly reported.
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LHCb Collaboration(Aaij, R. et al), Jaimes Elles, S. J., Jashal, B. K., Martinez-Vidal, F., Oyanguren, A., Rebollo De Miguel, M., et al. (2023). Measurement of the CKM angle γ using the B± → D*h± channels. J. High Energy Phys., 12(12), 013–32pp.
Abstract: A measurement of the CP-violating observables from B -> (DK +/-)-K-* and B-+/- -> D-*pi(+/-) decays is presented, where D-*(D) is an admixture of D-*0 and D-0 (D-0 and (0)) states and is reconstructed through the decay chains D-*-> D pi(0)/gamma and D -> KS0 pi+pi-/KS0K+K-. The measurement is performed by analysing the signal yield variation across the D decay phase space and is independent of any amplitude model. The data sample used was collected by the LHCb experiment in proton-proton collisions and corresponds to a total integrated luminosity of 9 fb(-1) at centre-of-mass energies of 7, 8 and 13 TeV. The CKM angle gamma is determined to be (69(-14)(+13))degrees using the measured CP-violating observables. The hadronic parameters r(B)(D)*(K +/-),r(B)(D)*(pi +/-),delta(D)(B)*(K +/-),delta(D)(B)*(pi +/-), which are the ratios and strong phase differences between favoured and suppressed B-+/- decays, are also reported.
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ANTARES Collaboration(Adrian-Martinez, S. et al), Aguilar, J. A., Bigongiari, C., Dornic, D., Emanuele, U., Gomez-Gonzalez, J. P., et al. (2011). First Search For Point Sources Of High-Energy Cosmic Neutrinos With The Antares Neutrino Telescope. Astrophys. J. Lett., 743(1), L14–6pp.
Abstract: Results are presented of a search for cosmic sources of high-energy neutrinos with the ANTARES neutrino telescope. The data were collected during 2007 and 2008 using detector configurations containing between 5 and 12 detection lines. The integrated live time of the analyzed data is 304 days. Muon tracks are reconstructed using a likelihood-based algorithm. Studies of the detector timing indicate a median angular resolution of 0.5 +/- 0.1 deg. The neutrino flux sensitivity is 7.5 x 10(-8)(E(v)/GeV)(-2) GeV(-1) s(-1) cm(-2) for the part of the sky that is always visible (delta < -48 deg), which is better than limits obtained by previous experiments. No cosmic neutrino sources have been observed.
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ANTARES Collaboration(Adrian-Martinez, S. et al), Barrios-Marti, J., Hernandez-Rey, J. J., Lambard, G., Mangano, S., Sanchez-Losa, A., et al. (2015). Search for muon-neutrino emission from GeV and TeV gamma-ray flaring blazars using five years of data of the ANTARES telescope. J. Cosmol. Astropart. Phys., 12(12), 014–27pp.
Abstract: The ANTARES telescope is well-suited for detecting astrophysical transient neutrino sources as it can observe a full hemisphere of the sky at all times with a high duty cycle. The background due to atmospheric particles can be drastically reduced, and the point-source sensitivity improved, by selecting a narrow time window around possible neutrino production periods. Blazars, being radio-loud active galactic nuclei with their jets pointing almost directly towards the observer, are particularly attractive potential neutrino point sources, since they are among the most likely sources of the very high-energy cosmic rays. Neutrinos and gamma rays may be produced in hadronic interactions with the surrounding medium. Moreover, blazars generally show high time variability in their light curves at different wavelengths and on various time scales. This paper presents a time-dependent analysis applied to a selection of flaring gamma-ray blazars observed by the FERMI/LAT experiment and by TeV Cherenkov telescopes using five years of ANTARES data taken from 2008 to 2012. The results are compatible with fluctuations of the background. Upper limits on the neutrino fluence have been produced and compared to the measured gamma-ray spectral energy distribution.
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Llosa, G., Trovato, M., Barrio, J., Etxebeste, A., Muñoz, E., Lacasta, C., et al. (2016). First Images of a Three-layer compton Telescope prototype for Treatment Monitoring in hadron Therapy. Front. Oncol., 6, 14–6pp.
Abstract: A Compton telescope for dose monitoring in hadron therapy is under development at IFIC. The system consists of three layers of LaBr3 crystals coupled to silicon photomulti-plier arrays. Na-22 sources have been successfully imaged reconstructing the data with an ML-EM code. Calibration and temperature stabilization are necessary for the prototype operation at low coincidence rates. A spatial resolution of 7.8 mm FWHM has been obtained in the first imaging tests.
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Gariazzo, S., de Salas, P. F., & Pastor, S. (2019). Thermalisation of sterile neutrinos in the early universe in the 3+1 scheme with full mixing matrix. J. Cosmol. Astropart. Phys., 07(7), 014–30pp.
Abstract: In the framework of a 3+1 scheme with an additional inert state, we consider the thermalisation of sterile neutrinos in the early Universe taking into account the full 4 x 4 mixing matrix. The evolution of the neutrino energy distributions is found solving the momentum-dependent kinetic equations with full diagonal collision terms, as in previous analyses of flavour neutrino decoupling in the standard case. The degree of thermalisation of the sterile state is shown in terms of the effective number of neutrinos, N-eff, and its dependence on the three additional mixing angles (theta(14), theta(24), theta(34)) and on the squared mass difference Delta m(41)(2) is discussed. Our results are relevant for fixing the contribution of a fourth light neutrino species to the cosmological energy density, whose value is very well constrained by the final Planck analysis. For the preferred region of active-sterile mixing parameters from short-baseline neutrino experiments, we find that the fourth state is fully thermalised (N-eff similar or equal to 4).
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Stadler, J., Boehm, C., & Mena, O. (2019). Comprehensive study of neutrino-dark matter mixed damping. J. Cosmol. Astropart. Phys., 08(8), 014–23pp.
Abstract: Mixed damping is a physical effect that occurs when a heavy species is coupled to a relativistic fluid which is itself free streaming. As a cross-case between collisional damping and free-streaming, it is crucial in the context of neutrino-dark matter interactions. In this work, we establish the parameter space relevant for mixed damping, and we derive an analytical approximation for the evolution of dark matter perturbations in the mixed damping regime to illustrate the physical processes responsible for the suppression of cosmological perturbations. Although extended Boltzmann codes implementing neutrino-dark matter scattering terms automatically include mixed damping, this effect has not been systematically studied. In order to obtain reliable numerical results, it is mandatory to reconsider several aspects of neutrino-dark matter interactions, such as the initial conditions, the ultra-relativistic fluid approximation and high order multiple moments in the neutrino distribution. Such a precise treatment ensures the correct assessment of the relevance of mixed damping in neutrino-dark matter interactions.
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HAWC Collaboration(Albert, A. et al), & Salesa Greus, F. (2020). HAWC and Fermi-LAT Detection of Extended Emission from the Unidentified Source 2HWC J2006+341. Astrophys. J. Lett., 903(1), L14–6pp.
Abstract: The discovery of the TeV point source 2HWC J2006+341 was reported in the second HAWC gamma-ray catalog. We present a follow-up study of this source here. The TeV emission is best described by an extended source with a soft spectrum. At GeV energies, an extended source is significantly detected in Fermi-LAT data. The matching locations, sizes, and spectra suggest that both gamma-ray detections correspond to the same source. Different scenarios for the origin of the emission are considered and we rule out an association to the pulsar PSR J2004+3429 due to extreme energetics required, if located at a distance of 10.8 kpc.
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