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Valdes-Cortez, C., Niatsetski, Y., Perez-Calatayud, J., Ballester, F., & Vijande, J. (2022). A Monte Carlo study of the relative biological effectiveness in surface brachytherapy. Med. Phys., 49, 5576–5588.
Abstract: Purpose This work aims to simulate clustered DNA damage from ionizing radiation and estimate the relative biological effectiveness (RBE) for radionuclide (rBT)- and electronic (eBT)-based surface brachytherapy through a hybrid Monte Carlo (MC) approach, using realistic models of the sources and applicators. Methods Damage from ionizing radiation has been studied using the Monte Carlo Damage Simulation algorithm using as input the primary electron fluence simulated using a state-of-the-art MC code, PENELOPE-2018. Two Ir-192 rBT applicators, Valencia and Leipzig, one Co-60 source with a Freiburg Flap applicator (reference source), and two eBT systems, Esteya and INTRABEAM, have been included in this study implementing full realizations of their geometries as disclosed by the manufacturer. The role played by filtration and tube kilovoltage has also been addressed. Results For rBT, an RBE value of about 1.01 has been found for the applicators and phantoms considered. In the case of eBT, RBE values for the Esteya system show an almost constant RBE value of about 1.06 for all depths and materials. For INTRABEAM, variations in the range of 1.12-1.06 are reported depending on phantom composition and depth. Modifications in the Esteya system, filtration, and tube kilovoltage give rise to variations in the same range. Conclusions Current clinical practice does not incorporate biological effects in surface brachytherapy. Therefore, the same absorbed dose is administered to the patients independently on the particularities of the rBT or eBT system considered. The almost constant RBE values reported for rBT support that assumption regardless of the details of the patient geometry, the presence of a flattening filter in the applicator design, or even significant modifications in the photon energy spectra above 300 keV. That is not the case for eBT, where a clear dependence on the eBT system and the characteristics of the patient geometry are reported. A complete study specific for each eBT system, including detailed applicator characteristics (size, shape, filtering, among others) and common anatomical locations, should be performed before adopting an existing RBE value.
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Agaras, M. N. et al, & Fiorini, L. (2023). Laser calibration of the ATLAS Tile Calorimeter during LHC Run 2. J. Instrum., 18(6), P06023–35pp.
Abstract: This article reports the laser calibration of the hadronic Tile Calorimeter of the ATLAS experiment in the LHC Run 2 data campaign. The upgraded Laser II calibration system is described. The system was commissioned during the first LHC Long Shutdown, exhibiting a stability better than 0.8% for the laser light monitoring. The methods employed to derive the detector calibration factors with data from the laser calibration runs are also detailed. These allowed to correct for the response fluctuations of the 9852 photomultiplier tubes of the Tile Calorimeter with a total uncertainty of 0.5% plus a luminosity-dependent sub-dominant term. Finally, we report the regular monitoring and performance studies using laser events in both standalone runs and during proton collisions. These studies include channel timing and quality inspection, and photomultiplier linearity and response dependence on anode current.
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Marco-Hernandez, R., Alves, D., Angoletta, M. E., Marqversen, O., Molendijk, J., Oponowicz, E., et al. (2017). The AD and ELENA orbit, trajectory and intensity measurement systems. J. Instrum., 12, P07024–24pp.
Abstract: This paper describes the new Antiproton Decelerator (AD) orbit measurement system and the Extra Low ENergy Antiproton ring (ELENA) orbit, trajectory and intensity measurement system. The AD machine at European Organization for Nuclear Research (CERN) is presently being used to decelerate antiprotons from 3.57 GeV/c to 100 MeV/c for matter vs anti-matter comparative studies. The ELENA machine, presently under commissioning, has been designed to provide an extra deceleration stage down to 13.7 MeV/c. The AD orbit system is based on 32 horizontal and 27 vertical electrostatic Beam Position Monitor (BPM) fitted with existing low noise front-end amplifiers while the ELENA system consists of 24 BPMs equipped with new low-noise head amplifiers. In both systems the front-end amplifiers generate a difference (delta) and a sum (sigma) signal which are sent to the digital acquisition system, placed tens of meters away from the AD or ELENA rings, where they are digitized and further processed. The beam position is calculated by dividing the difference signal by the sum signal either using directly the raw digitized data for measuring the turn-by-turn trajectory in the ELENA system or after down-mixing the signals to baseband for the orbit measurement in both machines. The digitized sigma signal will be used in the ELENA system to calculate the bunched beam intensity and the Schottky parameters with coasting beam after passing through different signal processing chain. The digital acquisition arrangement for both systems is based on the same hardware, also used in the ELENA Low Level Radio Frequency (LLRF) system, which follows the VME Switched Serial (VXS) enhancement of the Versa Module Eurocard 64x extension (VME64x) standard and includes VITA 57 standard Field Programmable Gate Array Mezzanine Card (FMC). The digital acquisition Field Programmable Gate Array (FPGA) andDigital Signal Processor (DSP) firmware sharesmany common functionalities with the LLRF system but has been tailored for this measurement application in particular. Specific control and acquisition software has been developed for these systems. Both systems are installed in AD and ELENA. The AD orbit system currently measures the orbit in AD while the ELENA system is being used in the commissioning of the ELENA ring.
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Ortiz Arciniega, J. L., Carrio, F., & Valero, A. (2019). FPGA implementation of a deep learning algorithm for real-time signal reconstruction in particle detectors under high pile-up conditions. J. Instrum., 14, P09002–13pp.
Abstract: The analog signals generated in the read-out electronics of particle detectors are shaped prior to the digitization in order to improve the signal to noise ratio (SNR). The real amplitude of the analog signal is then obtained using digital filters, which provides information about the energy deposited in the detector. The classical digital filters have a good performance in ideal situations with Gaussian electronic noise and no pulse shape distortion. However, high-energy particle colliders, such as the Large Hadron Collider (LHC) at CERN, can produce multiple simultaneous events, which produce signal pileup. The performance of classical digital filters deteriorates in these conditions since the signal pulse shape gets distorted. In addition, this type of experiments produces a high rate of collisions, which requires high throughput data acquisitions systems. In order to cope with these harsh requirements, new read-out electronics systems are based on high-performance FPGAs, which permit the utilization of more advanced real-time signal reconstruction algorithms. In this paper, a deep learning method is proposed for real-time signal reconstruction in high pileup particle detectors. The performance of the new method has been studied using simulated data and the results are compared with a classical FIR filter method. In particular, the signals and FIR filter used in the ATLAS Tile Calorimeter are used as benchmark. The implementation, resources usage and performance of the proposed Neural Network algorithm in FPGA are also presented.
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Gomez-Cadenas, J. J., Benlloch-Rodriguez, J. M., Ferrario, P., Monrabal, F., Rodriguez, J., & Toledo, J. F. (2016). Investigation of the coincidence resolving time performance of a PET scanner based on liquid xenon: a Monte Carlo study. J. Instrum., 11, P09011–18pp.
Abstract: The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the coincidence resolving time (CRT) of the gammas is sufficiently good. The best commercial PET-TOF system today (based in LYSO crystals and digital SiPMs), is the VEREOS of Philips, boasting a CRT of 316 ps (FWHM). In this paper we present a Monte Carlo investigation of the CRT performance of a PET scanner exploiting the scintillating properties of liquid xenon. We find that an excellent CRT of 70 ps (depending on the PDE of the sensor) can be obtained if the scanner is instrumented with silicon photomultipliers (SiPMs) sensitive to the ultraviolet light emitted by xenon. Alternatively, a CRT of 160 ps can be obtained instrumenting the scanner with (much cheaper) blue-sensitive SiPMs coated with a suitable wavelength shifter. These results show the excellent time of flight capabilities of a PET device based in liquid xenon.
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ATLAS Collaboration(Aad, G. et al), Aparisi Pozo, J. A., Bailey, A. J., Cabrera Urban, S., Castillo, F. L., Castillo Gimenez, V., et al. (2020). Performance of the ATLAS muon triggers in Run 2. J. Instrum., 15(9), P09015–57pp.
Abstract: The performance of the ATLAS muon trigger system is evaluated with proton-proton (pp) and heavy-ion (HI) collision data collected in Run 2 during 2015-2018 at the Large Hadron Collider. It is primarily evaluated using events containing a pair of muons from the decay of Z bosons to cover the intermediate momentum range between 26 GeV and 100 GeV. Overall, the efficiency of the single-muon triggers is about 68% in the barrel region and 85% in the endcap region. The p(T) range for efficiency determination is extended by using muons from decays of J/psi mesons, W bosons, and top quarks. The performance in HI collision data is measured and shows good agreement with the results obtained in pp collisions. The muon trigger shows uniform and stable performance in good agreement with the prediction of a detailed simulation. Dedicated multi-muon triggers with kinematic selections provide the backbone to beauty, quarkonia, and low-mass physics studies. The design, evolution and performance of these triggers are discussed in detail.
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NEXT Collaboration(Rogers, L. et al), Alvarez, V., Benlloch-Rodriguez, J. M., Botas, A., Carcel, S., Carrion, J. V., et al. (2018). High voltage insulation and gas absorption of polymers in high pressure argon and xenon gases. J. Instrum., 13, P10002–19pp.
Abstract: High pressure gas time projection chambers (HPGTPCs) are made with a variety of materials, many of which still await proper characterization in high pressure noble gas environments. As HPGTPCs increase in size toward ton-scale detectors, assemblies become larger and more complex, creating a need for detailed understanding of how structural supports and high voltage insulators behave. This includes identification of materials with predictable mechanical properties and without surface charge accumulation that may lead to field deformation or sparking. This paper explores the mechanical and electrical effects of high pressure gas environments on insulating polymers PTFE, HDPE, PEEK, POM and UHMW in argon and xenon, including studying gas absorption, swelling and high voltage insulation strength.
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T2K Collaboration(Abe, K. et al), Antonova, M., Cervera-Villanueva, A., Molina Bueno, L., & Novella, P. (2022). Scintillator ageing of the T2K near detectors fro 2010 to 2021. J. Instrum., 17(10), P10028–36pp.
Abstract: The T2K experiment widely uses plastic scintillator as a target for neutrino interactions and an active medium for the measurement of charged particles produced in neutrino interactions at its near detector complex. Over 10 years of operation the measured light yield recorded by the scintillator based subsystems has been observed to degrade by 0.9-2.2% per year. Extrapolation of the degradation rate through to 2040 indicates the recorded light yield should remain above the lower threshold used by the current reconstruction algorithms for all subsystems. This will allow the near detectors to continue contributing to important physics measurements during the T2K-II and Hyper-Kamiokande eras. Additionally, work to disentangle the degradation of the plastic scintillator and wavelength shifting fibres shows that the reduction in light yield can be attributed to the ageing of the plastic scintillator. The long component of the attenuation length of the wavelength shifting fibres was observed to degrade by 1.3-5.4% per year, while the short component of the attenuation length did not show any conclusive degradation.
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NEXT Collaboration(Monrabal, F. et al), Laing, A., Alvarez, V., Benlloch-Rodriguez, J. M., Carcel, S., Carrion, J. V., et al. (2018). The NEXT White (NEW) detector. J. Instrum., 13, P12010–38pp.
Abstract: Conceived to host 5 kg of xenon at a pressure of 15 bar in the fiducial volume, the NEXT-White apparatus is currently the largest high pressure xenon gas TPC using electroluminescent amplification in the world. It is also a 1:2 scale model of the NEXT-100 detector for Xe-136 beta beta 0 nu decay searches, scheduled to start operations in 2019. Both detectors measure the energy of the event using a plane of photomultipliers located behind a transparent cathode. They can also reconstruct the trajectories of charged tracks in the dense gas of the TPC with the help of a plane of silicon photomultipliers located behind the anode. A sophisticated gas system, common to both detectors, allows the high gas purity needed to guarantee a long electron lifetime. NEXT-White has been operating since October 2016 at the Laboratorio Subterraneo de Canfranc (LSC), in Spain. This paper describes the detector and associated infrastructures, as well as the main aspects of its initial operation.
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Al Kharusi, S. et al, & Colomer, M. (2021). SNEWS 2.0: a next-generation supernova early warning system for multi-messenger astronomy. New J. Phys., 23(3), 031201–34pp.
Abstract: The next core-collapse supernova in the Milky Way or its satellites will represent a once-in-a-generation opportunity to obtain detailed information about the explosion of a star and provide significant scientific insight for a variety of fields because of the extreme conditions found within. Supernovae in our galaxy are not only rare on a human timescale but also happen at unscheduled times, so it is crucial to be ready and use all available instruments to capture all possible information from the event. The first indication of a potential stellar explosion will be the arrival of a bright burst of neutrinos. Its observation by multiple detectors worldwide can provide an early warning for the subsequent electromagnetic fireworks, as well as signal to other detectors with significant backgrounds so they can store their recent data. The supernova early warning system (SNEWS) has been operating as a simple coincidence between neutrino experiments in automated mode since 2005. In the current era of multi-messenger astronomy there are new opportunities for SNEWS to optimize sensitivity to science from the next galactic supernova beyond the simple early alert. This document is the product of a workshop in June 2019 towards design of SNEWS 2.0, an upgraded SNEWS with enhanced capabilities exploiting the unique advantages of prompt neutrino detection to maximize the science gained from such a valuable event.
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